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Volumn 132, Issue 1, 2011, Pages 30-38

The interaction between HCV and nuclear receptor-mediated pathways

Author keywords

Autophagy; Hepatitis; Liver; Retinoic acid; Retinoic acid receptor; Steatosis

Indexed keywords

ALITRETINOIN; ANTIVIRUS AGENT; BEZAFIBRATE; CLOFIBRATE; FARNESOID X RECEPTOR; FENOFIBRATE; LIVER X RECEPTOR; PEGINTERFERON; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; RIBAVIRIN; ROSIGLITAZONE;

EID: 79960596493     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.05.005     Document Type: Review
Times cited : (6)

References (111)
  • 1
    • 21744438136 scopus 로고    scopus 로고
    • Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses
    • DOI 10.1002/jmv.20388
    • M.Y. Abdalla, I.M. Ahmad, D.R. Spitz, W.N. Schmidt, and B.E. Britigan Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses J Med Virol 76 2005 489 497 (Pubitemid 40943258)
    • (2005) Journal of Medical Virology , vol.76 , Issue.4 , pp. 489-497
    • Abdalla, M.Y.1    Ahmad, I.M.2    Spitz, D.R.3    Schmidt, W.N.4    Britigan, B.E.5
  • 2
    • 0034987263 scopus 로고    scopus 로고
    • Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
    • DOI 10.1053/jhep.2001.24432
    • L.E. Adinolfi, M. Gambardella, A. Andreana, M.F. Tripodi, R. Utili, and G. Ruggiero Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity Hepatology 33 2001 1358 1364 (Pubitemid 32496971)
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1358-1364
    • Adinolfi, L.E.1    Gambardella, M.2    Andreana, A.3    Tripodi, M.-F.4    Utili, R.5    Ruggiero, G.6
  • 3
    • 33748933183 scopus 로고    scopus 로고
    • Hepatitis C virus entry: Molecular biology and clinical implications
    • DOI 10.1002/hep.21321
    • H. Barth, T.J. Liang, and T.F. Baumert Hepatitis C virus entry: Molecular biology and clinical implications Hepatology 44 2006 527 535 (Pubitemid 44433708)
    • (2006) Hepatology , vol.44 , Issue.3 , pp. 527-535
    • Barth, H.1    Liang, T.J.2    Baumert, T.F.3
  • 4
    • 79953179826 scopus 로고    scopus 로고
    • Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease
    • S.W. Beaven, K. Wroblewski, J. Wang, C. Hong, S. Bensinger, and H. Tsukamoto Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease Gastroenterology 2010
    • (2010) Gastroenterology
    • Beaven, S.W.1    Wroblewski, K.2    Wang, J.3    Hong, C.4    Bensinger, S.5    Tsukamoto, H.6
  • 5
    • 77949725830 scopus 로고    scopus 로고
    • Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
    • K.D. Bissig, S.F. Wieland, P. Tran, M. Isogawa, T.T. Le, and F.V. Chisari Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment J Clin Invest 120 2010 924 930
    • (2010) J Clin Invest , vol.120 , pp. 924-930
    • Bissig, K.D.1    Wieland, S.F.2    Tran, P.3    Isogawa, M.4    Le, T.T.5    Chisari, F.V.6
  • 6
    • 77951430085 scopus 로고    scopus 로고
    • Gene expression profiling indicates the roles of host oxidative stress, apoptosis, lipid metabolism, and intracellular transport genes in the replication of hepatitis C virus
    • S. Blackham, A. Baillie, F. Al-Hababi, K. Remlinger, S. You, and R. Hamatake Gene expression profiling indicates the roles of host oxidative stress, apoptosis, lipid metabolism, and intracellular transport genes in the replication of hepatitis C virus J Virol 84 2010 5404 5414
    • (2010) J Virol , vol.84 , pp. 5404-5414
    • Blackham, S.1    Baillie, A.2    Al-Hababi, F.3    Remlinger, K.4    You, S.5    Hamatake, R.6
  • 7
    • 39549107777 scopus 로고    scopus 로고
    • All-trans retinoic acid for treatment of chronic hepatitis C
    • DOI 10.1111/j.1478-3231.2007.01666.x
    • W.O. Bocher, C. Wallasch, T. Hohler, and P.R. Galle All-trans retinoic acid for treatment of chronic hepatitis C Liver Int 28 2008 347 354 (Pubitemid 351279582)
    • (2008) Liver International , vol.28 , Issue.3 , pp. 347-354
    • Bocher, W.O.1    Wallasch, C.2    Hohler, T.3    Galle, P.R.4
  • 8
    • 47649114826 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner
    • DOI 10.1111/j.1600-0854.2008.00767.x
    • S. Boulant, M.W. Douglas, L. Moody, A. Budkowska, P. Targett-Adams, and J. McLauchlan Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner Traffic 9 2008 1268 1282 (Pubitemid 352016286)
    • (2008) Traffic , vol.9 , Issue.8 , pp. 1268-1282
    • Boulant, S.1    Douglas, M.W.2    Moody, L.3    Budkowska, A.4    Targett-Adams, P.5    McLauchlan, J.6
  • 9
    • 35448947488 scopus 로고    scopus 로고
    • Hepatitis C virus infection: In vivo and in vitro models
    • DOI 10.1111/j.1365-2893.2007.00918.x
    • V. Brass, D. Moradpour, and H.E. Blum Hepatitis C virus infection: In vivo and in vitro models J Viral Hepat 14 Suppl 1 2007 64 67 (Pubitemid 47624115)
    • (2007) Journal of Viral Hepatitis , vol.14 , Issue.SUPPL. 1 , pp. 64-67
    • Brass, V.1    Moradpour, D.2    Blum, H.E.3
  • 10
    • 59449097794 scopus 로고    scopus 로고
    • Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor
    • R. Bruck, S. Weiss, H. Aeed, M. Pines, Z. Halpern, and I. Zvibel Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor Dig Dis Sci 54 2009 292 299
    • (2009) Dig Dis Sci , vol.54 , pp. 292-299
    • Bruck, R.1    Weiss, S.2    Aeed, H.3    Pines, M.4    Halpern, Z.5    Zvibel, I.6
  • 11
    • 77953960796 scopus 로고    scopus 로고
    • Hepatitis C virus evasion of adaptive immune responses: A model for viral persistence
    • K.P. Burke, and A.L. Cox Hepatitis C virus evasion of adaptive immune responses: A model for viral persistence Immunol Res 47 2010 216 227
    • (2010) Immunol Res , vol.47 , pp. 216-227
    • Burke, K.P.1    Cox, A.L.2
  • 13
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • P. Chambon A decade of molecular biology of retinoic acid receptors FASEB J 10 1996 940 954 (Pubitemid 26285969)
    • (1996) FASEB Journal , vol.10 , Issue.9 , pp. 940-954
    • Chambon, P.1
  • 14
    • 35348837827 scopus 로고    scopus 로고
    • Bile acids promote the expression of hepatitis C virus in replicon-harboring cells
    • DOI 10.1128/JVI.00795-07
    • K.O. Chang, and D.W. George Bile acids promote the expression of hepatitis C virus in replicon-harboring cells J Virol 81 2007 9633 9640 (Pubitemid 350067669)
    • (2007) Journal of Virology , vol.81 , Issue.18 , pp. 9633-9640
    • Chang, K.-O.1    George, D.W.2
  • 17
    • 31644451456 scopus 로고    scopus 로고
    • Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor α and carnitine palmitoyl acyl-CoA transferase 1A
    • Y. Cheng, S. Dharancy, M. Malapel, and P. Desreumaux Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor alpha and carnitine palmitoyl acyl-CoA transferase 1A World J Gastroenterol 11 2005 7591 7596 (Pubitemid 43168421)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.48 , pp. 7591-7596
    • Cheng, Y.1    Dharancy, S.2    Malapel, M.3    Desreumaux, P.4
  • 20
    • 72049095072 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in chronic hepatitis C
    • M.W. Douglas, and J. George Molecular mechanisms of insulin resistance in chronic hepatitis C World J Gastroenterol 15 2009 4356 4364
    • (2009) World J Gastroenterol , vol.15 , pp. 4356-4364
    • Douglas, M.W.1    George, J.2
  • 21
    • 69549135689 scopus 로고    scopus 로고
    • The autophagy machinery is required to initiate hepatitis C virus replication
    • M. Dreux, P. Gastaminza, S.F. Wieland, and F.V. Chisari The autophagy machinery is required to initiate hepatitis C virus replication Proc Natl Acad Sci USA 106 2009 14046 14051
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14046-14051
    • Dreux, M.1    Gastaminza, P.2    Wieland, S.F.3    Chisari, F.V.4
  • 22
    • 40749143642 scopus 로고    scopus 로고
    • Early steps of the hepatitis C virus life cycle
    • DOI 10.1111/j.1462-5822.2007.01107.x
    • J. Dubuisson, F. Helle, and L. Cocquerel Early steps of the hepatitis C virus life cycle Cell Microbiol 10 2008 821 827 (Pubitemid 351386938)
    • (2008) Cellular Microbiology , vol.10 , Issue.4 , pp. 821-827
    • Dubuisson, J.1    Helle, F.2    Cocquerel, L.3
  • 24
    • 33644509858 scopus 로고    scopus 로고
    • Hepatitis C-identifying patients with progressive liver injury
    • J.J. Feld, and T.J. Liang Hepatitis C-identifying patients with progressive liver injury Hepatology 43 2006 S194 S206
    • (2006) Hepatology , vol.43
    • Feld, J.J.1    Liang, T.J.2
  • 27
    • 77956225515 scopus 로고    scopus 로고
    • Telaprevir: A new hope in the treatment of chronic hepatitis C?
    • A.J. Fowell, and K.L. Nash Telaprevir: A new hope in the treatment of chronic hepatitis C? Adv Ther 27 2010 512 522
    • (2010) Adv Ther , vol.27 , pp. 512-522
    • Fowell, A.J.1    Nash, K.L.2
  • 28
    • 33745193547 scopus 로고    scopus 로고
    • Effects of bezafibrate in patients with chronic hepatitis C virus infection: Combination with interferon and ribavirin
    • N. Fujita, M. Kaito, M. Kai, R. Sugimoto, H. Tanaka, and S. Horiike Effects of bezafibrate in patients with chronic hepatitis C virus infection: Combination with interferon and ribavirin J Viral Hepat 13 2006 441 448
    • (2006) J Viral Hepat , vol.13 , pp. 441-448
    • Fujita, N.1    Kaito, M.2    Kai, M.3    Sugimoto, R.4    Tanaka, H.5    Horiike, S.6
  • 29
    • 19644401237 scopus 로고    scopus 로고
    • Reduction of serum HCV RNA titer by bezafibrate therapy in patients with chronic hepatitis C [2]
    • DOI 10.1111/j.1572-0241.2004.40695-3.x
    • N. Fujita, M. Kaito, H. Tanaka, S. Horiike, and Y. Adachi Reduction of serum HCV RNA titer by bezafibrate therapy in patients with chronic hepatitis C Am J Gastroenterol 99 2004 2280 (Pubitemid 39524721)
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.11 , pp. 2280
    • Fujita, N.1    Kaito, M.2    Tanaka, H.3    Horiike, S.4    Adachi, Y.5
  • 31
    • 23944485662 scopus 로고    scopus 로고
    • Evasion of intracellular host defence by hepatitis C virus
    • DOI 10.1038/nature04078
    • M. Gale Jr., and E.M. Foy Evasion of intracellular host defence by hepatitis C virus Nature 436 2005 939 945 (Pubitemid 41191669)
    • (2005) Nature , vol.436 , Issue.7053 , pp. 939-945
    • Gale Jr., M.1    Foy, E.M.2
  • 32
    • 39749098739 scopus 로고    scopus 로고
    • Cellular determinants of hepatitis c virus assembly, maturation, degradation, and secretion
    • DOI 10.1128/JVI.02053-07
    • P. Gastaminza, G. Cheng, S. Wieland, J. Zhong, W. Liao, and F.V. Chisari Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion J Virol 82 2008 2120 2129 (Pubitemid 351293514)
    • (2008) Journal of Virology , vol.82 , Issue.5 , pp. 2120-2129
    • Gastaminza, P.1    Cheng, G.2    Wieland, S.3    Zhong, J.4    Liao, W.5    Chisari, F.V.6
  • 34
    • 1942533537 scopus 로고    scopus 로고
    • Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-alpha activator fenofibrate
    • DOI 10.1074/jbc.M400346200
    • P. Gervois, R. Kleemann, A. Pilon, F. Percevault, W. Koenig, and B. Staels Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-alpha activator fenofibrate J Biol Chem 279 2004 16154 16160 (Pubitemid 38509307)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.16 , pp. 16154-16160
    • Gervois, P.1    Kleemann, R.2    Pilon, A.3    Percevault, F.4    Koenig, W.5    Staels, B.6    Kooistra, T.7
  • 35
    • 77951602823 scopus 로고    scopus 로고
    • Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells
    • C.K. Glass, and K. Saijo Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells Nat Rev Immunol 10 2010 365 376
    • (2010) Nat Rev Immunol , vol.10 , pp. 365-376
    • Glass, C.K.1    Saijo, K.2
  • 36
    • 40049088000 scopus 로고    scopus 로고
    • PPARalpha: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
    • F.J. Gonzalez, and Y.M. Shah PPARalpha: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators Toxicology 246 2008 2 8
    • (2008) Toxicology , vol.246 , pp. 2-8
    • Gonzalez, F.J.1    Shah, Y.M.2
  • 37
    • 77955515860 scopus 로고    scopus 로고
    • Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection
    • C. Guevin, D. Manna, C. Belanger, K.V. Konan, P. Mak, and P. Labonte Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection Virology 405 2010 1 7
    • (2010) Virology , vol.405 , pp. 1-7
    • Guevin, C.1    Manna, D.2    Belanger, C.3    Konan, K.V.4    Mak, P.5    Labonte, P.6
  • 38
    • 77952574852 scopus 로고    scopus 로고
    • Pathogenesis of alcoholic liver disease: The role of nuclear receptors
    • M.A. Gyamfi, and Y.J. Wan Pathogenesis of alcoholic liver disease: The role of nuclear receptors Exp Biol Med (Maywood) 235 2010 547 560
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 547-560
    • Gyamfi, M.A.1    Wan, Y.J.2
  • 40
    • 77953767546 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2
    • C. Hong, S. Duit, P. Jalonen, R. Out, L. Scheer, and V. Sorrentino The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2 J Biol Chem 285 2010 19720 19726
    • (2010) J Biol Chem , vol.285 , pp. 19720-19726
    • Hong, C.1    Duit, S.2    Jalonen, P.3    Out, R.4    Scheer, L.5    Sorrentino, V.6
  • 41
    • 2342644813 scopus 로고    scopus 로고
    • Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
    • DOI 10.1002/hep.20170
    • E. Ip, G. Farrell, P. Hall, G. Robertson, and I. Leclercq Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice Hepatology 39 2004 1286 1296 (Pubitemid 38569050)
    • (2004) Hepatology , vol.39 , Issue.5 , pp. 1286-1296
    • Ip, E.1    Farrell, G.2    Hall, P.3    Robertson, G.4    Leclercq, I.5
  • 42
    • 76749130074 scopus 로고    scopus 로고
    • Disruption of PPARgamma signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy
    • M. Jiang, S. Fernandez, W.G. Jerome, Y. He, X. Yu, and H. Cai Disruption of PPARgamma signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy Cell Death Differ 17 2010 469 481
    • (2010) Cell Death Differ , vol.17 , pp. 469-481
    • Jiang, M.1    Fernandez, S.2    Jerome, W.G.3    He, Y.4    Yu, X.5    Cai, H.6
  • 43
    • 77649274843 scopus 로고    scopus 로고
    • The cell biology of hepatitis C virus
    • M.A. Joyce, and D.L. Tyrrell The cell biology of hepatitis C virus Microbes Infect 12 2010 263 271
    • (2010) Microbes Infect , vol.12 , pp. 263-271
    • Joyce, M.A.1    Tyrrell, D.L.2
  • 45
    • 77950602195 scopus 로고    scopus 로고
    • Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance
    • M. Khattab, M. Emad, A. Abdelaleem, M. Eslam, R. Atef, and Y. Shaker Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance Liver Int 30 2010 447 454
    • (2010) Liver Int , vol.30 , pp. 447-454
    • Khattab, M.1    Emad, M.2    Abdelaleem, A.3    Eslam, M.4    Atef, R.5    Shaker, Y.6
  • 47
    • 69249229453 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma
    • K. Kim, K.H. Kim, E. Ha, J.Y. Park, N. Sakamoto, and J. Cheong Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma FEBS Lett 583 2009 2720 2726
    • (2009) FEBS Lett , vol.583 , pp. 2720-2726
    • Kim, K.1    Kim, K.H.2    Ha, E.3    Park, J.Y.4    Sakamoto, N.5    Cheong, J.6
  • 48
    • 0037438377 scopus 로고    scopus 로고
    • Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
    • DOI 10.1182/blood-2002-06-1762
    • R. Kleemann, P.P. Gervois, L. Verschuren, B. Staels, H.M. Princen, and T. Kooistra Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation Blood 101 2003 545 551 (Pubitemid 36077576)
    • (2003) Blood , vol.101 , Issue.2 , pp. 545-551
    • Kleemann, R.1    Gervois, P.P.2    Verschuren, L.3    Staels, B.4    Princen, H.M.G.5    Kooistra, T.6
  • 49
    • 58849166220 scopus 로고    scopus 로고
    • Steatosis, liver injury, and hepatocarcinogenesis in hepatitis C viral infection
    • K. Koike Steatosis, liver injury, and hepatocarcinogenesis in hepatitis C viral infection J Gastroenterol 44 Suppl 19 2009 82 88
    • (2009) J Gastroenterol , vol.44 , Issue.SUPPL. 19 , pp. 82-88
    • Koike, K.1
  • 50
    • 34249793707 scopus 로고    scopus 로고
    • Structure and function of the atypical orphan nuclear receptor small heterodimer partner
    • DOI 10.1016/S0074-7696(07)61003-1, PII S0074769607610031, A Survey of Cell Biology
    • Y.S. Lee, D. Chanda, J. Sim, Y.Y. Park, and H.S. Choi Structure and function of the atypical orphan nuclear receptor small heterodimer partner Int Rev Cytol 261 2007 117 158 (Pubitemid 46856618)
    • (2007) International Review of Cytology , vol.261 , pp. 117-158
    • Lee, Y.1    Chanda, D.2    Sim, J.3    Park, Y.4    Choi, H.5
  • 51
    • 77953967458 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway
    • Z.H. Li, Q.B. Tang, J. Wang, L. Zhou, W.L. Huang, and R.Y. Liu Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway J Gastroenterol Hepatol 25 2010 1315 1320
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1315-1320
    • Li, Z.H.1    Tang, Q.B.2    Wang, J.3    Zhou, L.4    Huang, W.L.5    Liu, R.Y.6
  • 53
    • 70350132017 scopus 로고    scopus 로고
    • Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism
    • R.K. Lyn, D.C. Kennedy, S.M. Sagan, D.R. Blais, Y. Rouleau, and A.F. Pegoraro Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism Virology 394 2009 130 142
    • (2009) Virology , vol.394 , pp. 130-142
    • Lyn, R.K.1    Kennedy, D.C.2    Sagan, S.M.3    Blais, D.R.4    Rouleau, Y.5    Pegoraro, A.F.6
  • 54
    • 0036147354 scopus 로고    scopus 로고
    • A pharmacoepidemiological assessment of the effect of statins and fibrates on fibrinogen concentration
    • DOI 10.1016/S0021-9150(01)00552-4, PII S0021915001005524
    • P. Maison, L. Mennen, D. Sapinho, B. Balkau, J. Sigalas, and M.C. Chesnier A pharmacoepidemiological assessment of the effect of statins and fibrates on fibrinogen concentration Atherosclerosis 160 2002 155 160 (Pubitemid 34076650)
    • (2002) Atherosclerosis , vol.160 , Issue.1 , pp. 155-160
    • Maison, P.1    Mennen, L.2    Sapinho, D.3    Balkau, B.4    Sigalas, J.5    Chesnier, M.-C.6    Eschwege, E.7
  • 56
    • 0033594810 scopus 로고    scopus 로고
    • PPARα activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
    • N. Marx, G.K. Sukhova, T. Collins, P. Libby, and J. Plutzky PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells Circulation 99 1999 3125 3131 (Pubitemid 29289077)
    • (1999) Circulation , vol.99 , Issue.24 , pp. 3125-3131
    • Marx, N.1    Sukhova, G.K.2    Collins, T.3    Libby, P.4    Plutzky, J.5
  • 60
    • 15744376980 scopus 로고    scopus 로고
    • Expression of gastrointestinal glutathione peroxidase is inversely correlated to the presence of hepatitis C virus subgenomic RNA in human liver cells
    • DOI 10.1074/jbc.M413730200
    • M. Morbitzer, and T. Herget Expression of gastrointestinal glutathione peroxidase is inversely correlated to the presence of hepatitis C virus subgenomic RNA in human liver cells J Biol Chem 280 2005 8831 8841 (Pubitemid 40409572)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 8831-8841
    • Morbitzer, M.1    Herget, T.2
  • 62
    • 0032479423 scopus 로고    scopus 로고
    • Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue- and inducer-specific manner
    • DOI 10.1074/jbc.273.27.16710
    • K. Motojima, P. Passilly, J.M. Peters, F.J. Gonzalez, and N. Latruffe Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner J Biol Chem 273 1998 16710 16714 (Pubitemid 28311694)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.27 , pp. 16710-16714
    • Motojima, K.1    Passilly, P.2    Peters, J.M.3    Gonzalez, F.J.4    Latruffe, N.5
  • 63
    • 22044440709 scopus 로고    scopus 로고
    • Chronic hepatitis C: Genotypes 4 to 9
    • DOI 10.1016/j.cld.2005.05.010, PII S1089326105000425, Hepatitis C Virus
    • M.H. Nguyen, and E.B. Keeffe Chronic hepatitis C: Genotypes 4 to 9 Clin Liver Dis 9 2005 411 426 vi (Pubitemid 40968204)
    • (2005) Clinics in Liver Disease , vol.9 , Issue.3 , pp. 411-426
    • Nguyen, M.H.1    Keeffe, E.B.2
  • 64
    • 1542350630 scopus 로고    scopus 로고
    • NIH Consensus Statement on Management of Hepatitis C: 2002
    • NIH Consensus Statement on Management of Hepatitis C: 2002 NIH Consens State Sci Statements 19 2002 1 46
    • (2002) NIH Consens State Sci Statements , vol.19 , pp. 1-46
  • 65
    • 77953323499 scopus 로고    scopus 로고
    • Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells
    • Y. Nishimura-Sakurai, N. Sakamoto, K. Mogushi, S. Nagaie, M. Nakagawa, and Y. Itsui Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells J Gastroenterol 45 2010 523 536
    • (2010) J Gastroenterol , vol.45 , pp. 523-536
    • Nishimura-Sakurai, Y.1    Sakamoto, N.2    Mogushi, K.3    Nagaie, S.4    Nakagawa, M.5    Itsui, Y.6
  • 66
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • M. Okuda, K. Li, M.R. Beard, L.A. Showalter, F. Scholle, and S.M. Lemon Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein Gastroenterology 122 2002 366 375 (Pubitemid 34116988)
    • (2002) Gastroenterology , vol.122 , Issue.2 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6    Weinman, S.A.7
  • 67
    • 46349099383 scopus 로고    scopus 로고
    • Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin
    • K. Overbeck, D. Genne, A. Golay, and F. Negro Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin J Hepatol 49 2008 295 298
    • (2008) J Hepatol , vol.49 , pp. 295-298
    • Overbeck, K.1    Genne, D.2    Golay, A.3    Negro, F.4
  • 69
    • 34247895578 scopus 로고    scopus 로고
    • The Hepatitis C Virus Life Cycle as a Target for New Antiviral Therapies
    • DOI 10.1053/j.gastro.2007.03.116, PII S0016508507006427
    • J.M. Pawlotsky, S. Chevaliez, and J.G. McHutchison The hepatitis C virus life cycle as a target for new antiviral therapies Gastroenterology 132 2007 1979 1998 (Pubitemid 46695724)
    • (2007) Gastroenterology , vol.132 , Issue.5 , pp. 1979-1998
    • Pawlotsky, J.1    Chevaliez, S.2    McHutchison, J.G.3
  • 70
    • 34248671715 scopus 로고    scopus 로고
    • The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms
    • DOI 10.1002/hep.21634
    • V. Pazienza, S. Clement, P. Pugnale, S. Conzelman, M. Foti, and A. Mangia The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms Hepatology 45 2007 1164 1171 (Pubitemid 46775778)
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1164-1171
    • Pazienza, V.1    Clement, S.2    Pugnale, P.3    Conzelman, S.4    Foti, M.5    Mangia, A.6    Negro, F.7
  • 71
    • 77954168704 scopus 로고    scopus 로고
    • Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-{gamma} in Huh-7 cells
    • V. Pazienza, M. Vinciguerra, A. Andriulli, and A. Mangia Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-{gamma} in Huh-7 cells J Gen Virol 91 2010 1678 1686
    • (2010) J Gen Virol , vol.91 , pp. 1678-1686
    • Pazienza, V.1    Vinciguerra, M.2    Andriulli, A.3    Mangia, A.4
  • 72
    • 4344689449 scopus 로고    scopus 로고
    • Discovery of novel nuclear receptor modulating ligands: An integral role for peptide interaction profiling
    • DOI 10.1016/S1359-6446(04)03201-5, PII S1359644604032015
    • K.H. Pearce, M.A. Iannone, C.A. Simmons, and J.G. Gray Discovery of novel nuclear receptor modulating ligands: An integral role for peptide interaction profiling Drug Discov Today 9 2004 741 751 (Pubitemid 39140801)
    • (2004) Drug Discovery Today , vol.9 , Issue.17 , pp. 741-751
    • Pearce, K.H.1    Iannone, M.A.2    Simmons, C.A.3    Gray, J.G.4
  • 74
    • 60149090028 scopus 로고    scopus 로고
    • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
    • A. Ploss, M.J. Evans, V.A. Gaysinskaya, M. Panis, H. You, and Y.P. de Jong Human occludin is a hepatitis C virus entry factor required for infection of mouse cells Nature 457 2009 882 886
    • (2009) Nature , vol.457 , pp. 882-886
    • Ploss, A.1    Evans, M.J.2    Gaysinskaya, V.A.3    Panis, M.4    You, H.5    De Jong, Y.P.6
  • 75
    • 70449084685 scopus 로고    scopus 로고
    • Towards a small animal model for hepatitis C
    • A. Ploss, and C.M. Rice Towards a small animal model for hepatitis C EMBO Rep 10 2009 1220 1227
    • (2009) EMBO Rep , vol.10 , pp. 1220-1227
    • Ploss, A.1    Rice, C.M.2
  • 76
    • 0035871002 scopus 로고    scopus 로고
    • Differential involvement of peroxisome-proliferator-activated receptors α and δ in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine
    • DOI 10.1042/0264-6021:3550481
    • H. Poirier, I. Niot, M.C. Monnot, O. Braissant, C. Meunier-Durmort, and P. Costet Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine Biochem J 355 2001 481 488 (Pubitemid 32397809)
    • (2001) Biochemical Journal , vol.355 , Issue.2 , pp. 481-488
    • Poirier, H.1    Niot, I.2    Monnot, M.-C.3    Braissant, O.4    Meunier-Durmort, C.5    Costet, P.6    Pineau, T.7    Wahli, W.8    Willson, T.M.9    Besnard, P.10
  • 77
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • J.D. Rabinowitz, and E. White Autophagy and metabolism Science 330 2010 1344 1348
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 78
    • 30744432858 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication
    • DOI 10.1016/j.chembiol.2005.10.006, PII S1074552105003376
    • B. Rakic, S.M. Sagan, M. Noestheden, S. Belanger, X. Nan, and C.L. Evans Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication Chem Biol 13 2006 23 30 (Pubitemid 43099921)
    • (2006) Chemistry and Biology , vol.13 , Issue.1 , pp. 23-30
    • Rakic, B.1    Sagan, S.M.2    Noestheden, M.3    Belanger, S.4    Nan, X.5    Evans, C.L.6    Xie, X.S.7    Pezacki, J.P.8
  • 79
    • 0035658444 scopus 로고    scopus 로고
    • Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis
    • J.K. Reddy Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis Am J Physiol Gastrointest Liver Physiol 281 2001 G1333 G1339
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Reddy, J.K.1
  • 80
    • 37849019211 scopus 로고    scopus 로고
    • Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR
    • C. Scholtes, O. Diaz, V. Icard, A. Kaul, R. Bartenschlager, and V. Lotteau Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR J Hepatol 48 2008 192 199
    • (2008) J Hepatol , vol.48 , pp. 192-199
    • Scholtes, C.1    Diaz, O.2    Icard, V.3    Kaul, A.4    Bartenschlager, R.5    Lotteau, V.6
  • 81
    • 46249111657 scopus 로고    scopus 로고
    • Hepatitis C virus infection: Molecular pathways to metabolic syndrome
    • DOI 10.1002/hep.22269
    • M.Y. Sheikh, J. Choi, I. Qadri, J.E. Friedman, and A.J. Sanyal Hepatitis C virus infection: Molecular pathways to metabolic syndrome Hepatology 47 2008 2127 2133 (Pubitemid 351945577)
    • (2008) Hepatology , vol.47 , Issue.6 , pp. 2127-2133
    • Sheikh, M.Y.1    Choi, J.2    Qadri, I.3    Friedman, J.E.4    Sanyal, A.J.5
  • 82
    • 79251512287 scopus 로고    scopus 로고
    • Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes
    • S. Shrivastava, A. Raychoudhuri, R. Steele, R. Ray, and R.B. Ray Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes Hepatology 53 2011 406 414
    • (2011) Hepatology , vol.53 , pp. 406-414
    • Shrivastava, S.1    Raychoudhuri, A.2    Steele, R.3    Ray, R.4    Ray, R.B.5
  • 84
    • 50249087889 scopus 로고    scopus 로고
    • Perturbation of autophagic pathway by hepatitis C virus
    • D. Sir, C. Liang, W.L. Chen, J.U. Jung, and J.H. Ou Perturbation of autophagic pathway by hepatitis C virus Autophagy 4 2008 830 831
    • (2008) Autophagy , vol.4 , pp. 830-831
    • Sir, D.1    Liang, C.2    Chen, W.L.3    Jung, J.U.4    Ou, J.H.5
  • 85
    • 36749083957 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor α in transgenic mice: Implications for HCV-associated hepatocarcinogenesis
    • DOI 10.1002/ijc.23056
    • N. Tanaka, K. Moriya, K. Kiyosawa, K. Koike, and T. Aoyama Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: Implications for HCV-associated Hepatocarcinogenesis Int J Cancer 122 2008 124 131 (Pubitemid 350209986)
    • (2008) International Journal of Cancer , vol.122 , Issue.1 , pp. 124-131
    • Tanaka, N.1    Moriya, K.2    Kiyosawa, K.3    Koike, K.4    Aoyama, T.5
  • 86
    • 38849184816 scopus 로고    scopus 로고
    • PPARα activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice
    • DOI 10.1172/JCI33594
    • N. Tanaka, K. Moriya, K. Kiyosawa, K. Koike, F.J. Gonzalez, and T. Aoyama PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice J Clin Invest 118 2008 683 694 (Pubitemid 351206557)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.2 , pp. 683-694
    • Tanaka, N.1    Moriya, K.2    Kiyosawa, K.3    Koike, K.4    Gonzalez, F.J.5    Aoyama, T.6
  • 87
    • 79960570338 scopus 로고    scopus 로고
    • Retinoids, retinoic acid receptors, and cancer
    • X.H. Tang, and L.J. Gudas Retinoids, retinoic acid receptors, and cancer Annu Rev Pathol 2010
    • (2010) Annu Rev Pathol
    • Tang, X.H.1    Gudas, L.J.2
  • 88
    • 0035852689 scopus 로고    scopus 로고
    • Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism
    • DOI 10.1073/pnas.041479698
    • H. Tang, and A. McLachlan Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism Proc Natl Acad Sci USA 98 2001 1841 1846 (Pubitemid 32165585)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.4 , pp. 1841-1846
    • Tang, H.1    McLachlan, A.2
  • 91
    • 77149159568 scopus 로고    scopus 로고
    • The bile acid receptor FXR is a modulator of intestinal innate immunity
    • P. Vavassori, A. Mencarelli, B. Renga, E. Distrutti, and S. Fiorucci The bile acid receptor FXR is a modulator of intestinal innate immunity J Immunol 183 2009 6251 6261
    • (2009) J Immunol , vol.183 , pp. 6251-6261
    • Vavassori, P.1    Mencarelli, A.2    Renga, B.3    Distrutti, E.4    Fiorucci, S.5
  • 93
    • 75949122658 scopus 로고    scopus 로고
    • The protective role of pregnane X receptor in lipopolysaccharide/d- galactosamine-induced acute liver injury
    • K. Wang, I. Damjanov, and Y.J. Wan The protective role of pregnane X receptor in lipopolysaccharide/d-galactosamine-induced acute liver injury Lab Invest 90 2010 257 265
    • (2010) Lab Invest , vol.90 , pp. 257-265
    • Wang, K.1    Damjanov, I.2    Wan, Y.J.3
  • 95
    • 0037095629 scopus 로고    scopus 로고
    • 2(I) collagen promoter by retinoic acid and retinoid X receptors
    • DOI 10.1016/S0003-9861(02)00058-9, PII S0003986102000589
    • L. Wang, L.R. Tankersley, M. Tang, J.J. Potter, and E. Mezey Regulation of the murine alpha(2)(I) collagen promoter by retinoic acid and retinoid X receptors Arch Biochem Biophys 401 2002 262 270 (Pubitemid 34848629)
    • (2002) Archives of Biochemistry and Biophysics , vol.401 , Issue.2 , pp. 262-270
    • Wang, L.1    Rennie Tankersley, L.2    Tang, M.3    Potter, J.J.4    Mezey, E.5
  • 96
    • 43249128626 scopus 로고    scopus 로고
    • Nuclear receptors and inflammatory diseases
    • DOI 10.3181/0708-MR-231
    • K. Wang, and Y.J. Wan Nuclear receptors and inflammatory diseases Exp Biol Med (Maywood) 233 2008 496 506 (Pubitemid 351657351)
    • (2008) Experimental Biology and Medicine , vol.233 , Issue.5 , pp. 496-506
    • Wang, K.1    Wan, Y.-J.Y.2
  • 97
    • 79953196869 scopus 로고    scopus 로고
    • A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease
    • M.L. Washburn, M.T. Bility, L. Zhang, G.I. Kovalev, A. Buntzman, and J.A. Frelinger A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease Gastroenterology 140 2011 1334 1344
    • (2011) Gastroenterology , vol.140 , pp. 1334-1344
    • Washburn, M.L.1    Bility, M.T.2    Zhang, L.3    Kovalev, G.I.4    Buntzman, A.5    Frelinger, J.A.6
  • 98
    • 0142123224 scopus 로고    scopus 로고
    • Modulation of Retinoid Signaling by a Cytoplasmic Viral Protein via Sequestration of Sp110b, a Potent Transcriptional Corepressor of Retinoic Acid Receptor, from the Nucleus
    • DOI 10.1128/MCB.23.21.7498-7509.2003
    • K. Watashi, M. Hijikata, A. Tagawa, T. Doi, H. Marusawa, and K. Shimotohno Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus Mol Cell Biol 23 2003 7498 7509 (Pubitemid 37271451)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.21 , pp. 7498-7509
    • Watashi, K.1    Hijikata, M.2    Tagawa, A.3    Doi, T.4    Marusawa, H.5    Shimotohno, K.6
  • 99
    • 77955673008 scopus 로고    scopus 로고
    • Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro
    • S.D. Woodhouse, R. Narayan, S. Latham, S. Lee, R. Antrobus, and B. Gangadharan Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro Hepatology 52 2010 443 453
    • (2010) Hepatology , vol.52 , pp. 443-453
    • Woodhouse, S.D.1    Narayan, R.2    Latham, S.3    Lee, S.4    Antrobus, R.5    Gangadharan, B.6
  • 102
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • L. Yang, P. Li, S. Fu, E.S. Calay, and G.S. Hotamisligil Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance Cell Metab 11 2010 467 478
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 103
    • 36949024511 scopus 로고    scopus 로고
    • The PPARα-humanized mouse: A model to investigate species differences in liver toxicity mediated by PPARα
    • DOI 10.1093/toxsci/kfm206
    • Q. Yang, T. Nagano, Y. Shah, C. Cheung, S. Ito, and F.J. Gonzalez The PPAR alpha-humanized mouse: A model to investigate species differences in liver toxicity mediated by PPAR alpha Toxicol Sci 101 2008 132 139 (Pubitemid 350239017)
    • (2008) Toxicological Sciences , vol.101 , Issue.1 , pp. 132-139
    • Yang, Q.1    Nagano, T.2    Shah, Y.3    Cheung, C.4    Ito, S.5    Gonzalez, F.J.6
  • 104
    • 77949272197 scopus 로고    scopus 로고
    • Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with hepatitis C virus
    • K. Yasui, Y. Harano, H. Mitsuyoshi, K. Tsuji, M. Endo, and T. Nakajima Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with hepatitis C virus J Gastroenterol 45 2010 95 104
    • (2010) J Gastroenterol , vol.45 , pp. 95-104
    • Yasui, K.1    Harano, Y.2    Mitsuyoshi, H.3    Tsuji, K.4    Endo, M.5    Nakajima, T.6
  • 105
    • 0346003777 scopus 로고    scopus 로고
    • Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression
    • DOI 10.1074/jbc.M210062200
    • S. Yu, K. Matsusue, P. Kashireddy, W.Q. Cao, V. Yeldandi, and A.V. Yeldandi Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression J Biol Chem 278 2003 498 505 (Pubitemid 36043602)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.1 , pp. 498-505
    • Yu, S.1    Matsusue, K.2    Kashireddy, P.3    Cao, W.-Q.4    Yeldandi, V.5    Yeldandi, A.V.6    Rao, M.S.7    Gonzalez, F.J.8    Reddy, J.K.9
  • 106
    • 77953806617 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro
    • J. Yu, S. Zhang, E.S. Chu, M.Y. Go, R.H. Lau, and J. Zhao Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro Int J Biochem Cell Biol 42 2010 948 957
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 948-957
    • Yu, J.1    Zhang, S.2    Chu, E.S.3    Go, M.Y.4    Lau, R.H.5    Zhao, J.6
  • 107
    • 67649210759 scopus 로고    scopus 로고
    • Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
    • S. Zhang, J. Wang, Q. Liu, and D.C. Harnish Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis J Hepatol 51 2009 380 388
    • (2009) J Hepatol , vol.51 , pp. 380-388
    • Zhang, S.1    Wang, J.2    Liu, Q.3    Harnish, D.C.4
  • 109
    • 76649100139 scopus 로고    scopus 로고
    • Liver X receptor in cholesterol metabolism
    • C. Zhao, and K. Dahlman-Wright Liver X receptor in cholesterol metabolism J Endocrinol 204 2010 233 240
    • (2010) J Endocrinol , vol.204 , pp. 233-240
    • Zhao, C.1    Dahlman-Wright, K.2
  • 110
    • 33744948052 scopus 로고    scopus 로고
    • A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway
    • DOI 10.1074/jbc.M511116200
    • J. Zhou, Y. Zhai, Y. Mu, H. Gong, H. Uppal, and D. Toma A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway J Biol Chem 281 2006 15013 15020 (Pubitemid 43855205)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.21 , pp. 15013-15020
    • Zhou, J.1    Zhai, Y.2    Mu, Y.3    Gong, H.4    Uppal, H.5    Toma, D.6    Ren, S.7    Evans, R.M.8    Xie, W.9


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