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Volumn 19, Issue 15, 2011, Pages 4499-4505

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging

(9) Evens, Nele a Vandeputte, Caroline a Muccioli, Giulio G b Lambert, Didier M b Baekelandt, Veerle a Verbruggen, Alfons M a Debyser, Zeger a Van Laere, Koen a Bormans, Guy M a

a UNIVERSITY OF LEUVEN (Belgium)

b UNIVERSITÉ CATHOLIQUE DE LOUVAIN (Belgium)

Author keywords

18F FE GW405833; MicroPET; Neuroinflammation; Type 2 cannabinoid receptor

Indexed keywords

1 (2,3 DICHLOROBENZOYL) 5 (2 FLUORETHOXY) 2 METHYL 3 [2 (4 MORPHOLINYL)ETHYL] 1H INDOLE; 1 (2,3 DICHLOROBENZOYL) 5 HYDROXY 2 METHYL 3 [2 (4 MORPHOLINYL)ETHYL] 1H INDOLE; 1 BROMO 2 FLUOROETHANE 1 (2,3 DICHLOROBENZOYL) 5 METHOXY 2 METHYL 3 [2 (4 MORPHOLINYL)ETHYL] 1H INDOLE F 18; 1 BROMO 2 FLUOROETHANE F 18; CANNABINOID 2 RECEPTOR; CANNABINOID 2 RECEPTOR AGONIST; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DEMETHYLATION; DRUG SCREENING; DRUG SYNTHESIS; HALF LIFE TIME; HISTOLOGY; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; BRAIN; FLUORINE RADIOISOTOPES; HUMANS; INDOLES; MALE; MICE; MORPHOLINES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; RATS; RECEPTOR, CANNABINOID, CB2;

MUS; RATTUS;

EID: 79960563429 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.06.033 Document Type: Article

Times cited : (50)

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