The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production

Reproductive Toxicology

Volumn 32, Issue 1, 2011, Pages 77-84

  Akgul, Yucel ^a   Derk, Raymond C ^b   Meighan, Terence ^b   Rao, K Murali Krishna ^b   Murono, Eisuke P ^a,b  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Cholesterol side chain cleavage; HPTE; Luteal cells; Methoxychlor; Ovarian steroidogenesis; P450scc

Indexed keywords

1,1,1 TRICHLORO 2,2 BIS(4 HYDROXYPHENYL)ETHANE; 3',5' DICHLORO 2 HYDROXY 2 METHYLBUT 3 ENANILIDE; 4,4' ISOPROPYLIDENEDIPHENOL; 8 BROMO CYCLIC AMP; ANTIANDROGEN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; ESTRADIOL; FLUTAMIDE; FULVESTRANT; METHOXYCHLOR; MONOBUTYLPHTHALATE; OCTYLPHENOL; PHENOL DERIVATIVE; PROGESTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; LUTEAL CELL; NONHUMAN; PROGESTERONE SYNTHESIS; RAT; REPRODUCTIVE TOXICITY;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; ESTROGENS; FEMALE; GENE EXPRESSION; LUTEAL CELLS; PHENOLS; PROGESTERONE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

RATTUS;

EID: 79960473399     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.05.013     Document Type: Article

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