The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats

Reproductive Toxicology

Volumn 19, Issue 1, 2004, Pages 135-146

  Murono, Eisuke P ^a   Derk, Raymond C ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

HPTE; Leydig cell; Testosterone

Indexed keywords

1,1,1 TRICHLORO 2,2 BIS(4 HYDROXYPHENYL)ETHANE; ALKANE DERIVATIVE; ANDROGEN RECEPTOR; ANTIANDROGEN; CHOLESTEROL; CHORIONIC GONADOTROPIN; ESTROGEN RECEPTOR; HORMONE RECEPTOR STIMULATING AGENT; METHOXYCHLOR; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; LEYDIG CELL; LIPID METABOLISM; MALE; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; TESTOSTERONE SYNTHESIS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ESTROGEN ANTAGONISTS; FLUTAMIDE; INSECTICIDES; LEYDIG CELLS; MALE; METHOXYCHLOR; OXAZOLES; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

EID: 4444220687     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2004.06.010     Document Type: Article

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