The biflavonoid amentoflavone induces apoptosis via suppressing E7 expression, cell cycle arrest at Sub-G 1 phase, and mitochondria-emanated intrinsic pathways in human cervical cancer cells

Journal of Medicinal Food

Volumn 14, Issue 7-8, 2011, Pages 808-816

  Lee, Sojung ^a   Kim, Heejong ^a   Kang, Jeong Woo ^a   Kim, Jung Hee ^a   Lee, Dong Hun ^a   Kim, Man Sub ^a   Yang, Young ^b   Woo, Eun Rhan ^c   Kim, Yang Mi ^a   Hong, Jintae ^d   Yoon, Do Young ^a  

^a Konkuk University   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Chosun University   (South Korea)

^d Chungbuk National University   (South Korea)

Author keywords

antitumor; apoptosis; cell cycle arrest; cervical cancer; flavonoids

Indexed keywords

AMENTOFLAVONE; CASPASE 3; CASPASE 9; CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; CYCLINE; CYCLOOXYGENASE 2; CYTOCHROME C; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 32; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN E7; PROTEIN KINASE B; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDICINAL PLANT; MITOCHONDRIA EMANATED INTRINSIC PATHWAY; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SELAGINELLA TAMARISCINA; SIGNAL TRANSDUCTION; UTERINE CERVIX CANCER;

APOPTOSIS; BIFLAVONOIDS; CELL CYCLE; DOWN-REGULATION; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN PAPILLOMAVIRUS 16; HUMANS; MITOCHONDRIA; PAPILLOMAVIRUS E7 PROTEINS; PLANT EXTRACTS; SELAGINELLACEAE; SIGNAL TRANSDUCTION; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS; SELAGINELLA TAMARISCINA;

EID: 79960452032     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2010.1428     Document Type: Article

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