Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide as well as proinflammatory cytokine production in B16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages

Journal of Experimental Therapeutics and Oncology

Volumn 7, Issue 3, 2008, Pages 207-218

  Guruvayoorappan, Chandrasekharan ^a   Kuttan, Girija ^a  

^a AMALA CANCER RESEARCH CENTRE   (India)

Author keywords

Amentoflavone; Apoptosis; Cytokines; Nitric oxide; Tumor associated macrophages

Indexed keywords

AMENTOFLAVONE; ANTIBODY; CASPASE 3; DNA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; PROTEIN BCL 2; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER PREVENTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA FRAGMENTATION; DRUG ISOLATION; DRUG MECHANISM; GENE EXPRESSION; MELANOMA; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; APOPTOSIS; BIFLAVONOIDS; CASPASE 3; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION, NEOPLASTIC; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 56749184013     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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