A diversity-oriented-synthesis protocol for scaffold discovery based on a general synthetic route to spirocycles

Tetrahedron Letters

Volumn 52, Issue 32, 2011, Pages 4204-4206

  Kang, Fu An ^a   Sui, Zhihua ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Diversity oriented synthesis; Drug discovery; Library design; Scaffold discovery; Spirocycle

Indexed keywords

ACORENONE B; AMINOKETONE; FREDERICAMYCIN A; LACTAM; LACTAM DERIVATIVE; MOLECULAR SCAFFOLD; SPIRO COMPOUND; SPIROCYCLIC KETOAMINE; SPIROCYCLIC KETOLACTAM; SPRIOFORNABUXINE; UNCLASSIFIED DRUG; VETIVONE;

ALLYLATION; ARTICLE; CLINICAL PROTOCOL; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROBORATION; HYDROGENATION; OXIDATION;

EID: 79960422784     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.06.020     Document Type: Article

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