Antioxidative effects of berberine pre-treatment on hydrogen peroxide-induced PC12 cell toxicity

Neural Regeneration Research

Volumn 5, Issue 18, 2010, Pages 1391-1395

  Xu, Daohua ^a   Zhou, Chenhui ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Berberine; Neural regeneration; Oxidative stress; PC12 cells; Reactive oxygen

Indexed keywords

BERBERINE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME RELEASE; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 79960383145     PISSN: 16735374     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2010.18.005     Document Type: Article

References (32)

1. Cedazo-Mínguez A. Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J Cell Mol Med. 2007;11(6):1227-1238.
2. Massaad CA, Amin SK, Hu L, et al. Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease. PLoS One. 2010;5(5):e10561.
3. Mosconi L, Pupi A, De Leon MJ. Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease. Ann N Y Acad Sci. 2008;1147:180-195.
4. Reddy VP, Zhu X, Perry G, et al. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis. 2009;16(4):763-774.
5. Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med. 2008;14(2):45-53.
6. Montiel T, Quiroz-Baez R, Massieu L, et al. Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: protection by antioxidants. Exp Neurol. 2006;200(2):496-508.
7. Baloyannis SJ. Mitochondrial alterations in Alzheimer's disease. J Alzheimers Dis. 2006;9(2):119-126.
8. Choi SJ, Kim MJ, Heo HJ, et al. Ameliorating effect of Gardenia jasminoides extract on amyloid beta peptide-induced neuronal cell deficit. Mol Cells. 2007;24(1):113-118.
9. Allen S, Britton JR, Leonardi-Bee JA. Association between antioxidant vitamins and asthma outcome measures: systematic review and meta-analysis. Thorax. 2009;64(7):610-619.
10. Vingtdeux V, Dreses-Werringloer U, Zhao H, et al. Therapeutic potential of resveratrol in Alzheimer's disease. BMC Neurosci. 2008;9 Suppl 2:S6.
11. Schmeller T, Latz-Brüning B, Wink M. Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores. Phytochemistry. 1997;44(2):257-266.
12. Jeong HW, Hsu KC, Lee JW, et al. Berberine suppresses proinflammatory responses through AMPK activation in macrophages. Am J Physiol Endocrinol Metab. 2009;296(4): 955-964.
13. Kong W, Wei J, Abidi P, et al. Berberine is a novel cholesterollowering drug working through a unique mechanism distinct from statins. Nat Med. 2004;10(12):1344-1351.
14. Hwang JM, Kuo HC, Tseng TH, et al. Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells. Arch Toxicol. 2006;80(2):62-73.
15. Choi MS, Yuk DY, Oh JH, et al. Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis. Anticancer Res. 2008;28(6A):3777-3784.
16. Zhu F, Qian C.Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease. BMC Neurosci. 2006;7:78.
17. Zhang J, Yang JQ, He BC, et al. Berberine and total base from rhizoma coptis chinensis attenuate brain injury in an aluminum-induced rat model of neurodegenerative disease. Saudi Med J. 2009;30(6):760-766.
18. Hirose M, Takatori M, Kuroda Y, et al. Effect of synthetic cell-penetrating peptides on TrkA activity in PC12 cells. J Pharmacol Sci. 2008;106(1):107-113.
19. Xu W, Zha RP, Wang WY, et al. Effects of scutellarin on PKCgamma in PC12 cell injury induced by oxygen and glucose deprivation. Acta Pharmacol Sin. 2007;28(10):1573-1579.
20. Chai XY, Li FF, Bai CC, et al. Three new acylated glycosides from the stems of Casearia velutina and their protective effect against H2O2-induced impairment in PC12 cells. Planta Med. 2010;76(1): 91-93.
21. Hwang SL, Yen GC. Modulation of Akt, JNK, and p38 activation is involved in citrus flavonoid-mediated cytoprotection of PC12 cells challenged by hydrogen peroxide. J Agric Food Chem. 2009;57(6): 2576-2582.
22. Iuvone T, De Filippis D, Esposito G, et al. The spice sage and its active ingredient rosmarinic acid protect PC12 cells from amyloid-beta peptide-induced neurotoxicity. J Pharmacol Exp Ther. 2006;317(3):1143-1149.
23. Aziz DM. Assessment of bovine sperm viability by MTT reduction assay. Anim Reprod Sci. 2006;92(1-2):1-8.
24. Zhao L, Chen Q, Diaz Brinton R. Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons. Exp Biol Med (Maywood). 2002;227(7):509-519.
25. Occhiuto F, Zangla G, Samperi S, et al. The phytoestrogenic isoflavones from Trifolium pratense L. (Red clover) protects human cortical neurons from glutamate toxicity. Phytomedicine. 2008;15(9):676-682.
26. Addabbo F, Montagnani M, Goligorsky MS. Mitochondria and reactive oxygen species. Hypertension. 2009;53(6):885-892.
27. Smith MA, Zhu X, Tabaton M, et al. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010;19(1):363-372.
28. Moreira PI, Sayre LM, Zhu X, et al. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010;610:419-434.
29. Tan Y, Tang Q, Hu BR, et al. Antioxidant properties of berberine on cultured rabbit corpus cavernosum smooth muscle cells injured by hydrogen peroxide. Acta Pharmacol Sin. 2007;28(12):1914-1918.
30. Meeran SM, Katiyar S, Katiyar SK. Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation. Toxicol Appl Pharmacol. 2008;229(1):33-43.
31. Wang L, Tang Y, Huang S. Protective effects of schisandrin B and schisandrin on oxidative damage in PC12 Cells. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2006;10(47):64-67.
32. Pelicano H, Feng L, Zhou Y, et al. Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem. 2003;278(39):37832-37839