Evidence for reduced selection pressure on the hepatitis B virus core gene in hepatitis B e antigen-negative chronic hepatitis B

Journal of General Virology

Volumn 92, Issue 8, 2011, Pages 1800-1808

  Warner, Brook G ^a   Tsai, Peter ^a   Rodrigo, Allen G ^a,b   'Ofanoa, Malakai ^a   Gane, Edward J ^c   Munn, Stephen R ^c   Abbott, William G H ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b DUKE UNIVERSITY   (United States)

^c AUCKLAND CITY HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B CORE ANTIGEN; HLA ANTIGEN CLASS 1;

ADULT; ARTICLE; CODON; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC SELECTION; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HLA SYSTEM; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; NATURAL SELECTION; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; SELECTION PRESSURE; VIRUS IMMUNITY; VIRUS REPLICATION;

ADULT; AMINO ACID SEQUENCE; FEMALE; HEPATITIS B CORE ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; SELECTION, GENETIC;

HEPATITIS B VIRUS;

EID: 79960346980     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.030478-0     Document Type: Article

References (36)

1. Abbott, W. G., Tukuitonga, C. F., Ofanoa, M., Munn, S. R. & Gane, E. J. (2006a). Low-cost, simultaneous, single-sequence genotyping of the HLA-A, HLA-B and HLA-C loci. Tissue Antigens 68, 28-37.
2. Abbott, W. G., Winship, I. M., Gane, E. J., Finau, S. A., Munn, S. R. & Tukuitonga, C. E. (2006b). Genetic diversity and linkage disequilibrium in the Polynesian population of Niue Island. Hum Biol 78, 131-145.
3. Abbott, W. G., Tsai, P., Leung, E., Trevarton, A., Ofanoa, M., Hornell, J., Gane, E. J., Munn, S. R. & Rodrigo, A. G. (2010). Associations between HLA class I alleles and escape mutations in the hepatitis B virus core gene in New Zealand-resident Tongans. J Virol 84, 621-629.
4. Akarca, U. S. & Lok, A. S. (1995). Naturally occurring hepatitis B virus core gene mutations. Hepatology 22, 50-60.
5. Bertoletti, A., Costanzo, A., Chisari, F. V., Levrero, M., Artini, M., Sette, A., Penna, A., Giuberti, T., Fiaccadori, F. & Ferrari, C. (1994). Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. J Exp Med 180, 933-943.
6. Boni, C., Fisicaro, P., Valdatta, C., Amadei, B., Di Vincenzo, P., Giuberti, T., Laccabue, D., Zerbini, A., Cavalli, A. & other authors (2007). Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection. J Virol 81, 4215-4225.
7. Chin, R. & Locarnini, S. (2003). Treatment of chronic hepatitis B: current challenges and future directions. Rev Med Virol 13, 255-272.
8. Crawford, H., Prado, J. G., Leslie, A., Hué, S., Honeyborne, I., Reddy, S., van der Stok, M., Mncube, Z., Brander, C. & other authors (2007). Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection. J Virol 81, 8346-8351.
9. del Guercio, M. F., Sidney, J., Hermanson, G., Perez, C., Grey, H. M., Kubo, R. T. & Sette, A. (1995). Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype. J Immunol 154, 685-693.
10. Durantel, D. & Zoulim, F. (2009). Innate response to hepatitis B virus infection: observations challenging the concept of a stealth virus. Hepatology 50, 1692-1695.
11. Guindon, S., Rodrigo, A. G., Dyer, K. A. & Huelsenbeck, J. P. (2004). Modeling the site-specific variation of selection patterns along lineages. Proc Natl Acad Sci U S A 101, 12957-12962.
12. Günther, S. (2006). Genetic variation in HBV infection: genotypes and mutants. J Clin Virol 36 (Suppl. 1), S3-S11.
13. Hannoun, C., Horal, P. & Lindh, M. (2000). Long-term mutation rates in the hepatitis B virus genome. J Gen Virol 81, 75-83.
14. Hirankarn, N., Manonom, C., Tangkijvanich, P. & Poovorawan, Y. (2007). Association of interleukin-18 gene polymorphism (-607A/A genotype) with susceptibility to chronic hepatitis B virus infection. Tissue Antigens 70, 160-163.
15. Hsu, H. Y., Chang, M. H., Ni, Y. H. & Chen, H. L. (2004). Survey of hepatitis B surface variant infection in children 15 years after a nationwide vaccination programme in Taiwan. Gut 53, 1499-1503.
16. Liaw, Y. F. (2009). Natural history of chronic hepatitis B virus infection and long-term outcome under treatment. Liver Int 29 (Suppl. 1), 100-107.
17. Liaw, Y. F., Leung, N., Kao, J. H., Piratvisuth, T., Gane, E., Han, K. H., Guan, R., Lau, G. K., Locarnini, S. & For the Chronic Hepatitis B Guideline Working Party of the Asian-Pacific Association for the Study of the Liver (2008). Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int 2, 263-283.
18. Lim, S. G., Cheng, Y., Guindon, S., Seet, B. L., Lee, L. Y., Hu, P., Wasser, S., Peter, F. J., Tan, T. & other authors (2007). Viral quasispecies evolution during hepatitis Be antigen seroconversion. Gastroenterology 133, 951-958.
19. Lin, T. M., Chen, C. J., Wu, M. M., Yang, C. S., Chen, J. S., Lin, C. C., Kwang, T. Y., Hsu, S. T., Lin, S. Y. & Hsu, L. C. (1989). Hepatitis B virus markers in Chinese twins. Anticancer Res 9, 737-741.
20. Lok, A. S. & McMahon, B. J. (2007). Chronic hepatitis B. Hepatology 45, 507-539.
21. Lok, A. S., Heathcote, E. J. & Hoofnagle, J. H. (2001). Management of hepatitis B: 2000-summary of a workshop. Gastroenterology 120, 1828-1853.
22. Lok, A. S., Zoulim, F., Locarnini, S., Bartholomeusz, A., Ghany, M. G., Pawlotsky, J. M., Liaw, Y. F., Mizokami, M., Kuiken, C. &Hepatitis B Virus Drug Resistance Working Group (2007). Antiviral drugresistant HBV: standardization of nomenclature and assays and recommendations for management. Hepatology 46, 254-265.
23. Lucifora, J., Durantel, D., Testoni, B., Hantz, O., Levrero, M. & Zoulim, F. (2010). Control of hepatitis B virus replication by innate response of HepaRG cells. Hepatology 51, 63-72.
24. Milich, D. & Liang, T. J. (2003). Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection. Hepatology 38, 1075-1086.
25. Missale, G., Redeker, A., Person, J., Fowler, P., Guilhot, S., Schlicht, H. J., Ferrari, C. & Chisari, F. V. (1993). HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis. J Exp Med 177, 751-762.
26. Publicover, J., Goodsell, A., Nishimura, S., Vilarinho, S., Wang, Z. E., Avanesyan, L., Spolski, R., Leonard, W. J., Cooper, S. & Baron, J. L. (2011). IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B. J Clin Invest 121, 1154-1162.
27. Reijnders, J. G., Perquin, M. J., Zhang, N., Hansen, B. E. & Janssen, H. L. (2010). Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B. Gastroenterology 139, 491-498.
28. Scheuer, P. J. (1970). Liver biopsy in the diagnosis of cirrhosis. Gut 11, 275-278.
29. Sendi, H., Mehrab-Mohseni, M., Shahraz, S., Norder, H., Alavian, S. M., Noorinayer, B., Zali, M. R., Pumpens, P., Bonkovsky, H. L. & Magnius, L. O. (2009). CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA. J Clin Virol 46, 259-264.
30. Sobao, Y., Sugi, K., Tomiyama, H., Saito, S., Fujiyama, S., Morimoto, M., Hasuike, S., Tsubouchi, H., Tanaka, K. & Takiguch, M. (2001). Identification of hepatitis B virus-specific CTL epitopes presented by HLA-A*2402, themost common HLA class I allele in East Asia. J Hepatol 34, 922-929.
31. Visvanathan, K., Skinner, N. A., Thompson, A. J., Riordan, S. M., Sozzi, V., Edwards, R., Rodgers, S., Kurtovic, J., Chang, J. & other authors (2007). Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein. Hepatology 45, 102-110.
32. Whalley, S. A., Brown, D., Webster, G. J., Jacobs, R., Reignat, S., Bertoletti, A., Teo, C. G., Emery, V. & Dusheiko, G. M. (2004). Evolution of hepatitis B virus during primary infection in humans: transient generation of cytotoxic T-cell mutants. Gastroenterology 127, 1131-1138.
33. Wu, J. F., Wu, T. C., Chen, C. H., Ni, Y. H., Chen, H. L., Hsu, H. Y. & Chang, M. H. (2010). Serum levels of interleukin-10 and interleukin- 12 predict early, spontaneous hepatitis B virus e antigen seroconversion. Gastroenterology 138, 165-172, e1-e3.
34. Wu, S., Imazeki, F., Kurbanov, F., Fukai, K., Arai, M., Kanda, T., Yonemitsu, Y., Tanaka, Y., Mizokami, M. & Yokosuka, O. (2011). Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion. J Hepatol 54, 19-25.
35. Yamashiro, T., Nagayama, K., Enomoto, N., Watanabe, H., Miyagi, T., Nakasone, H., Sakugawa, H. & Watanabe, M. (2004). Quantitation of the level of hepatitis delta virus RNA in serum, by real-time polymerase chain reaction and its possible correlation with the clinical stage of liver disease. J Infect Dis 189, 1151-1157.
36. Yang, Z., Wong, W. S. & Nielsen, R. (2005). Bayes empirical bayes inference of amino acid sites under positive selection. Mol Biol Evol 22, 1107-1118.