Heat shock protein 90 mediates cytoprotection by H2S against chemical hypoxia-induced injury in PC12 cells

Clinical and Experimental Pharmacology and Physiology

Volumn 38, Issue 1, 2011, Pages 42-49

  Meng, Jin Lan ^a,c   Mei, Wei Yi ^b   Dong, Yan Fen ^c   Wang, Jian Hong ^c   Zhao, Chun Mei ^a   Lan, Ai Ping ^a   Yang, Chun Tao ^a   Chen, Pei Xi ^a   Feng, Jian Qiang ^a   Hu, Chen Heng ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Chemical hypoxia; Cytoprotection; Heat shock protein; Hydrogen sulphide; Oxidative stress

Indexed keywords

COBALT CHLORIDE; HEAT SHOCK PROTEIN 90; HYDROGEN SULFIDE; REACTIVE OXYGEN METABOLITE; SODIUM SULFIDE; TANESPIMYCIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; ANOXIA; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; COBALT; CYTOPROTECTION; CYTOTOXINS; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; HSP90 HEAT-SHOCK PROTEINS; HYDROGEN SULFIDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEUROPROTECTIVE AGENTS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES;

EID: 78650658740     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05462.x     Document Type: Article

References (36)

1. Wang R. The gasotransmitter role of hydrogen sulfide. Antioxid. Redox Signal. 2003; 5: 493-501.
2. Kimura Y, Kimura H. Hydrogen sulfide protects neurons from oxidative stress. FASEB J. 2004; 18: 1165-7.
3. Li L, Bhatia M, Zhu YZ et al. Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J. 2005; 19: 1196-8.
4. Whiteman M, Armstrong JS, Chu SH et al. The novel neuromodulator hydrogen sulfide: An endogenous peroxynitrite 'scavenger'? J. Neurochem. 2004; 90: 765-8.
5. Chahl LA. Hydrogen sulphide: An endogenous stimulant of capsaicin-sensitive primary afferent neurons? Br. J. Pharmacol. 2004; 142: 1-2.
6. Laggner H, Muellner MK, Schreier S et al. Hydrogen sulphide: A novel physiological inhibitor of LDL atherogenic modification by HOCl. Free Radic. Res. 2007; 41: 741-7.
7. Tang XQ, Yang CT, Chen J et al. Effect of hydrogen sulphide on β-amyloid-induced damage in PC12 cells. Clin. Exp. Pharmacol. Physiol. 2008; 35: 180-6.
8. Whiteman M, Cheung NS, Zhu YZ et al. Hydrogen sulphide: A novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem. Biophys. Res. Commun. 2005; 326: 794-8.
9. Zhang LM, Jiang CX, Liu DW. Hydrogen sulfide attenuates neuronal injury induced by vascular dementia via inhibiting apoptosis in rats. Neurochem. Res. 2009; 34: 1984-92.
10. Tay AS, Hu LF, Lu M, Wong PT, Bian JS. Hydrogen sulfide protects neurons against hypoxic injury via stimulation of ATP-sensitive potassium channel/protein kinase C/extracellular signal-regulated kinase/heat shock protein 90 pathway. Neuroscience 2010; 167: 277-86.
11. Terasawa K, Minami M, Minami Y. Constantly updated knowledge of Hsp90. J. Biochem. 2005; 137: 443-7.
12. Pandey P, Saleh A, Nakazawa A et al. Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J. 2000; 19: 4310-22.
13. Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P, Rosen N. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function. J. Biol. Chem. 2002; 277: 39858-66.
14. Georgakis GV, Li Y, Younes A. The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9. Br. J. Haematol. 2006; 135: 68-71.
15. Chen JX, Meyrick B. Hypoxia increases Hsp90 binding to eNOS via PI3K-Akt in porcine coronary artery endothelium. Lab. Invest. 2004; 84: 182-90.
16. Kupatt C, Dessy C, Hinkel R et al. Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. Arterioscler. Thromb. Vasc. Biol. 2004; 24: 1435-41.
17. + channel-mediated hypoxic preconditioning. Cardiovasc. Res. 2008; 77: 126-33.
18. Zou W, Yan M, Xu W et al. Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation. J. Neurosci. Res. 2001; 64: 646-53.
19. 2-induced apoptosis in rat PC12 cells. Life Sci. 2007; 80: 1355-63.
20. Roman GC. Vascular dementia revisited. Diagnosis, pathogenesis, treatment, and prevention. Med. Clin. North Am. 2002; 86: 477-99.
21. Chen SL, Yang CT, Yang ZL et al. Hydrogen sulphide protects H9c2 cells against chemical hypoxia-induced injury. Clin. Exp. Pharmacol. Physiol. 2010; 37: 316-21.
22. Hosoki R, Matsuki N, Kimura H. The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem. Biophys. Res. Commun. 1997; 237: 527-31.
23. Reiffenstein RJ, Hulbert WC, Roth SH. Toxicology of hydrogen sulfide. Annu. Rev. Pharmacol. Toxicol. 1992; 32: 109-34.
24. Abe K, Kimura H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J. Neurosci. 1996; 16: 1066-71.
25. Kimura Y, Goto Y, Kimura H. Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid. Redox Signal. 2010; 12: 1-13.
26. Hu LF, Lu M, Wu ZY, Wong PT, Bian JS. Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol. Pharmacol. 2009; 75: 27-34.
27. Yin WL, He JQ, Hu B, Jiang ZS, Tang XQ. Hydrogen sulfide inhibits MPP(+)-induced apoptosis in PC12 cells. Life Sci. 2009; 85: 269-75.
28. Qu K, Chen CP, Halliwell B, Moore PK, Wong PT. Hydrogen sulfide is a mediator of cerebral ischemic damage. Stroke 2006; 37: 889-93.
29. Cheung NS, Peng ZF, Chen MJ, Moore PK, Whiteman M. Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons. Neuropharmacology 2007; 53: 505-14.
30. Li L, Moore PK. Putative biological roles of hydrogen sulfide in health and disease: A breath of not so fresh air? Trends Pharmacol. Sci. 2008; 29: 84-90.
31. Geng B, Chang L, Pan C et al. Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem. Biophys. Res. Commun. 2004; 318: 756-63.
32. Yao M, Nguyen TV, Pike CJ. Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w. J. Neurosci. 2005; 25: 1149-58.
33. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 1999; 341: 233-49.
34. Akao M, O'Rourke B, Teshima Y, Seharaseyon J, Marban E. Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes. Circ. Res. 2003; 92: 186-94.
35. Jha S, Calvert JW, Duranski MR, Ramachandran A, Lefer DJ. Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: Role of antioxidant and antiapoptotic signaling. Am. J. Physiol. Heart Circ. Physiol. 2008; 295: H801-6.
36. Lewis J, Devin A, Miller A et al. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J. Biol. Chem. 2000; 275: 10519-26.