COX-2 Inhibition Improves Immune System Homeostasis and Decreases Liver Damage in Septic Rats

Journal of Surgical Research

Volumn 157, Issue 1, 2009, Pages 43-47

  Li, Bin ^a   Li, Yu Min ^a   Li, Xun ^a   Shi, Bin ^a   He, Ming Yan ^a   Zhu, Xiao Liang ^a   Zhou, Wen Ce ^a   Wachtel, Mitchell S ^b   Frezza, Eldo ^b  

^a LANZHOU UNIVERSITY   (China)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

cyclooxygenase 2; cytokines; liver damage; NS 398; sepsis; T cells

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYCLOOXYGENASE 2; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4 CD8 RATIO; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; HOMEOSTASIS; IMMUNE RESPONSE; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYTOKINES; HEPATOCYTES; HOMEOSTASIS; LIVER DISEASES; MALE; MICROSCOPY, ELECTRON; NITROBENZENES; RATS; RATS, WISTAR; RNA, MESSENGER; SEPSIS; SULFONAMIDES; T-LYMPHOCYTES;

EID: 70349804292     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.12.020     Document Type: Article

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