Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways

Journal of Cell Science

Volumn 124, Issue 13, 2011, Pages 2208-2219

  Yokoyama, Akihiko ^a   Ficara, Francesca ^b   Murphy, Mark J ^b   Meisel, Christian ^b   Naresh, Alpana ^b   Kitabayashi, Issay ^a   Cleary, Michael L ^b  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Degradation; MLL; Proteolysis

Indexed keywords

HOMEODOMAIN PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; MUTANT PROTEIN; PHENYLALANINE; PROTEASOME; TYROSINE;

ALLELE; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOPLASM; DEGRADATION KINETICS; GENETIC ENGINEERING; HUMAN; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; T CELL LEUKEMIA;

ANIMALS; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LEUKEMIA, T-CELL; MICE; MICE, KNOCKOUT; MUTATION; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 79960303005     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.080523     Document Type: Article

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