Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis

Molecular Cell

Volumn 38, Issue 6, 2010, Pages 853-863

  Milne, Thomas A ^a   Kim, Jaehoon ^a   Wang, Gang G ^a   Stadler, Sonja C ^a   Basrur, Venkatesha ^c   Whitcomb, Sarah J ^a   Wang, Zhanxin ^b   Ruthenburg, Alexander J ^a   Elenitoba Johnson, Kojo S J ^c   Roeder, Robert G ^a   Allis, C David ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

DNA; HUMDISEASE; PROTEINS

Indexed keywords

DNA; HYBRID PROTEIN; MLL1 FUSION PROTEIN; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; MLL AF9 FUSION PROTEIN, MOUSE; MLL PROTEIN, MOUSE; MLL-AF9 FUSION PROTEIN, MOUSE; NUCLEAR PROTEIN; ONCOPROTEIN; PAF1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LEUKEMOGENESIS; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; WILD TYPE; ANIMAL; CELL LINE; GENE LOCUS; GENETICS; HUMAN; LEUKEMIA; METABOLISM; POINT MUTATION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

ANIMALS; CELL LINE; GENETIC LOCI; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA; MICE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT;

EID: 77953913196     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.05.011     Document Type: Article

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