-
1
-
-
34250865564
-
CDC25 phosphatases in cancer cells: key players? Good targets?
-
Boutros, R., Lobjois, V. and Ducommun, B. (2007). CDC25 phosphatases in cancer cells: key players? Good targets? Nat. Rev. Cancer 7, 495-507.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
2
-
-
0035799557
-
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
-
Bulavin, D. V., Higashimoto, Y., Popoff, I. J., Gaarde, W. A., Basrur, V., Potapova, O., Appella, E. and Fornace, A. J., Jr. (2001). Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 411, 102-107.
-
(2001)
Nature
, vol.411
, pp. 102-107
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Popoff, I.J.3
Gaarde, W.A.4
Basrur, V.5
Potapova, O.6
Appella, E.7
Fornace Jr., A.J.8
-
3
-
-
3242878502
-
Claspin, a regulator of Chk1 in DNA replication stress pathway
-
Chini, C. C. and Chen, J. (2004). Claspin, a regulator of Chk1 in DNA replication stress pathway. DNA Repair 3, 1033-1037.
-
(2004)
DNA Repair
, vol.3
, pp. 1033-1037
-
-
Chini, C.C.1
Chen, J.2
-
4
-
-
47749141560
-
ATR: an essential regulator of genome integrity
-
Cimprich, K. A. and Cortez, D. (2008). ATR: an essential regulator of genome integrity. Nat. Rev. 9, 616-627.
-
(2008)
Nat. Rev.
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
5
-
-
0034713226
-
Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events
-
De Souza, C. P., Ellem, K. A. and Gabrielli, B. G. (2000). Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events. Exp. Cell Res. 257, 11-21.
-
(2000)
Exp. Cell Res.
, vol.257
, pp. 11-21
-
-
De Souza, C.P.1
Ellem, K.A.2
Gabrielli, B.G.3
-
6
-
-
0037096158
-
From Cdc2 to Cdk1: when did the cell cycle kinase join its cyclin partner?
-
Doree, M. and Hunt, T. (2002). From Cdc2 to Cdk1: when did the cell cycle kinase join its cyclin partner? J. Cell Sci. 115, 2461-2464.
-
(2002)
J Cell Sci
, vol.115
, pp. 2461-2464
-
-
Doree, M.1
Hunt, T.2
-
7
-
-
71749099636
-
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition
-
Enomoto, M., Goto, H., Tomono, Y., Kasahara, K., Tsujimura, K., Kiyono, T. and Inagaki, M. (2009). Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition. J. Biol. Chem. 284, 34223-34230.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34223-34230
-
-
Enomoto, M.1
Goto, H.2
Tomono, Y.3
Kasahara, K.4
Tsujimura, K.5
Kiyono, T.6
Inagaki, M.7
-
8
-
-
0029937532
-
Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells
-
Gabrielli, B. G., De Souza, C. P., Tonks, I. D., Clark, J. M., Hayward, N. K. and Ellem, K. A. (1996). Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells. J. Cell Sci. 109, 1081-1093.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1081-1093
-
-
Gabrielli, B.G.1
De Souza, C.P.2
Tonks, I.D.3
Clark, J.M.4
Hayward, N.K.5
Ellem, K.A.6
-
9
-
-
57049126143
-
Human protein factory for converting the transcriptome into an in vitro-expressed proteome
-
Goshima, N., Kawamura, Y., Fukumoto, A., Miura, A., Honma, R., Satoh, R., Wakamatsu, A., Yamamoto, J., Kimura, K., Nishikawa, T. et al. (2008). Human protein factory for converting the transcriptome into an in vitro-expressed proteome. Nat. Methods 5, 1011-1017.
-
(2008)
Nat. Methods
, vol.5
, pp. 1011-1017
-
-
Goshima, N.1
Kawamura, Y.2
Fukumoto, A.3
Miura, A.4
Honma, R.5
Satoh, R.6
Wakamatsu, A.7
Yamamoto, J.8
Kimura, K.9
Nishikawa, T.10
-
10
-
-
33244490241
-
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition
-
Goto, H., Kiyono, T., Tomono, Y., Kawajiri, A., Urano, T., Furukawa, K., Nigg, E. A. and Inagaki, M. (2006). Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat. Cell Biol. 8, 180-187.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 180-187
-
-
Goto, H.1
Kiyono, T.2
Tomono, Y.3
Kawajiri, A.4
Urano, T.5
Furukawa, K.6
Nigg, E.A.7
Inagaki, M.8
-
11
-
-
56349099694
-
Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation
-
Ikegami, Y., Goto, H., Kiyono, T., Enomoto, M., Kasahara, K., Tomono, Y., Tozawa, K., Morita, A., Kohri, K. and Inagaki, M. (2008). Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation. Biochem. Biophys. Res. Commun. 377, 227-1231.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 1227-1231
-
-
Ikegami, Y.1
Goto, H.2
Kiyono, T.3
Enomoto, M.4
Kasahara, K.5
Tomono, Y.6
Tozawa, K.7
Morita, A.8
Kohri, K.9
Inagaki, M.10
-
12
-
-
0037322744
-
Active cyclin B1-Cdk1 first appears on centrosomes in prophase
-
Jackman, M., Lindon, C., Nigg, E. A. and Pines, J. (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat. Cell Biol. 5, 143-48.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 143-148
-
-
Jackman, M.1
Lindon, C.2
Nigg, E.A.3
Pines, J.4
-
13
-
-
0042242580
-
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345
-
Jiang, K., Pereira, E., Maxfield, M., Russell, B., Goudelock, D. M. and Sanchez, Y. (2003). Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J. Biol. Chem. 278, 25207-25217.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25207-25217
-
-
Jiang, K.1
Pereira, E.2
Maxfield, M.3
Russell, B.4
Goudelock, D.M.5
Sanchez, Y.6
-
14
-
-
0033538847
-
Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis
-
Karlsson, C., Katich, S., Hagting, A., Hoffmann, I. and Pines, J. (1999). Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis. J. Cell Biol. 146, 573-584.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 573-584
-
-
Karlsson, C.1
Katich, S.2
Hagting, A.3
Hoffmann, I.4
Pines, J.5
-
15
-
-
77955849465
-
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage
-
Kasahara, K., Goto, H., Enomoto, M., Tomono, Y., Kiyono, T. and Inagaki, M. (2010). 14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage. EMBO J. 29, 2802-2812.
-
(2010)
EMBO J
, vol.29
, pp. 2802-2812
-
-
Kasahara, K.1
Goto, H.2
Enomoto, M.3
Tomono, Y.4
Kiyono, T.5
Inagaki, M.6
-
16
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M. B. and Bartek, J. (2004). Cell-cycle checkpoints and cancer. Nature 432, 316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
17
-
-
17444434208
-
Facile methods for generating human somatic cell gene knockouts using recombinant adenoassociated viruses
-
Kohli, M., Rago, C., Lengauer, C., Kinzler, K. W. and Vogelstein, B. (2004). Facile methods for generating human somatic cell gene knockouts using recombinant adenoassociated viruses. Nucleic Acids Res. 32, e3.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Kohli, M.1
Rago, C.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
18
-
-
4444345565
-
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
-
Kramer, A., Mailand, N., Lukas, C., Syljuasen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. and Lukas, J. (2004). Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat. Cell Biol. 6, 884-891.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 884-891
-
-
Kramer, A.1
Mailand, N.2
Lukas, C.3
Syljuasen, R.G.4
Wilkinson, C.J.5
Nigg, E.A.6
Bartek, J.7
Lukas, J.8
-
19
-
-
26444493574
-
Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome
-
Lindqvist, A., Kallstrom, H., Lundgren, A., Barsoum, E. and Rosenthal, C. K. (2005). Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. J. Cell Biol. 171, 35-45.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 35-45
-
-
Lindqvist, A.1
Kallstrom, H.2
Lundgren, A.3
Barsoum, E.4
Rosenthal, C.K.5
-
20
-
-
65349102972
-
The decision to enter mitosis: feedback and redundancy in the mitotic entry network
-
Lindqvist, A., Rodriguez-Bravo, V. and Medema, R. H. (2009). The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J. Cell Biol. 185, 193-202.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 193-202
-
-
Lindqvist, A.1
Rodriguez-Bravo, V.2
Medema, R.H.3
-
21
-
-
35848964048
-
DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function
-
Loffler, H., Bochtler, T., Fritz, B., Tews, B., Ho, A. D., Lukas, J., Bartek, J. and Kramer, A. (2007). DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function. Cell Cycle 6, 2541-2548.
-
(2007)
Cell Cycle
, vol.6
, pp. 2541-2548
-
-
Loffler, H.1
Bochtler, T.2
Fritz, B.3
Tews, B.4
Ho, A.D.5
Lukas, J.6
Bartek, J.7
Kramer, A.8
-
22
-
-
11344286593
-
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation
-
Manke, I. A., Nguyen, A., Lim, D., Stewart, M. Q., Elia, A. E. and Yaffe, M. B. (2005). MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation. Mol. Cell 17, 37-48.
-
(2005)
Mol. Cell
, vol.17
, pp. 37-48
-
-
Manke, I.A.1
Nguyen, A.2
Lim, D.3
Stewart, M.Q.4
Elia, A.E.5
Yaffe, M.B.6
-
23
-
-
2342584830
-
Cdc25A regulation: to destroy or not to destroy-is that the only question
-
Neely, K. E. and Piwnica-Worms, H. (2003). Cdc25A regulation: to destroy or not to destroy-is that the only question? Cell Cycle 2, 455-457.
-
(2003)
Cell Cycle
, vol.2
, pp. 455-457
-
-
Neely, K.E.1
Piwnica-Worms, H.2
-
24
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
Nigg, E. A. (2001). Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell Biol. 2, 21-32.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 21-32
-
-
Nigg, E.A.1
-
25
-
-
28244497051
-
Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe
-
Niida, H., Tsuge, S., Katsuno, Y., Konishi, A., Takeda, N. and Nakanishi, M. (2005). Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe. J. Biol. Chem. 280, 39246-39252.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39246-39252
-
-
Niida, H.1
Tsuge, S.2
Katsuno, Y.3
Konishi, A.4
Takeda, N.5
Nakanishi, M.6
-
26
-
-
34147206546
-
Specific role of Chk1 phosphorylations in cell survival and checkpoint activation
-
Niida, H., Katsuno, Y., Banerjee, B., Hande, M. P. and Nakanishi, M. (2007). Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol. Cell. Biol. 27, 2572-2581.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2572-2581
-
-
Niida, H.1
Katsuno, Y.2
Banerjee, B.3
Hande, M.P.4
Nakanishi, M.5
-
27
-
-
0036901957
-
Cyclin dependent kinases and cell cycle control (Nobel lecture)
-
Nurse, P. (2002). Cyclin dependent kinases and cell cycle control (Nobel lecture). Chembiochem 3, 596-603.
-
(2002)
Chembiochem
, vol.3
, pp. 596-603
-
-
Nurse, P.1
-
28
-
-
39149117397
-
Genetic knockouts and knockins in human somatic cells
-
Rago, C., Vogelstein, B. and Bunz, F. (2007). Genetic knockouts and knockins in human somatic cells. Nat. Protoc. 2, 2734-2746.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2734-2746
-
-
Rago, C.1
Vogelstein, B.2
Bunz, F.3
-
29
-
-
34247269029
-
TAO kinases mediate activation of p38 in response to DNA damage
-
Raman, M., Earnest, S., Zhang, K., Zhao, Y. and Cobb, M. H. (2007). TAO kinases mediate activation of p38 in response to DNA damage. EMBO J. 6, 2005-2014.
-
(2007)
EMBO J
, vol.26
, pp. 2005-2014
-
-
Raman, M.1
Earnest, S.2
Zhang, K.3
Zhao, Y.4
Cobb, M.H.5
-
30
-
-
63749131243
-
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
-
Reinhardt, H. C. and Yaffe, M. B. (2009). Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Curr. Opin. Cell iol. 21, 245-255.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 245-255
-
-
Reinhardt, H.C.1
Yaffe, M.B.2
-
31
-
-
33846821915
-
p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
-
Reinhardt, H. C., Aslanian, A. S., Lees, J. A. and Yaffe, M. B. (2007). p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. Cancer Cell 11, 175-189.
-
(2007)
Cancer Cell
, vol.11
, pp. 175-189
-
-
Reinhardt, H.C.1
Aslanian, A.S.2
Lees, J.A.3
Yaffe, M.B.4
-
32
-
-
77957361354
-
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization
-
Reinhardt, H. C., Hasskamp, P., Schmedding, I., Morandell, S., van Vugt, M. A., Wang, X., Linding, R., Ong, S. E., Weaver, D., Carr, S. A. et al. (2010). DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization. Mol. Cell 40, 4-49.
-
(2010)
Mol. Cell
, vol.40
, pp. 34-49
-
-
Reinhardt, H.C.1
Hasskamp, P.2
Schmedding, I.3
Morandell, S.4
van Vugt, M.A.5
Wang, X.6
Linding, R.7
Ong, S.E.8
Weaver, D.9
Carr, S.A.10
-
33
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H. and Elledge, S. J. (1997). Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
34
-
-
38649118240
-
Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression
-
Shimada, M., Niida, H., Zineldeen, D. H., Tagami, H., Tanaka, M., Saito, H. and Nakanishi, M. (2008). Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression. Cell 132, 221-232.
-
(2008)
Cell
, vol.132
, pp. 221-232
-
-
Shimada, M.1
Niida, H.2
Zineldeen, D.H.3
Tagami, H.4
Tanaka, M.5
Saito, H.6
Nakanishi, M.7
-
35
-
-
33645800984
-
Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1)
-
Shiromizu, T., Goto, H., Tomono, Y., Bartek, J., Totsukawa, G., Inoko, A., Nakanishi, M., Matsumura, F. and Inagaki, M. (2006). Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1). Genes Cells 11, 477-485.
-
(2006)
Genes Cells
, vol.11
, pp. 477-485
-
-
Shiromizu, T.1
Goto, H.2
Tomono, Y.3
Bartek, J.4
Totsukawa, G.5
Inoko, A.6
Nakanishi, M.7
Matsumura, F.8
Inagaki, M.9
-
36
-
-
77951753826
-
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry
-
Splinter, D., Tanenbaum, M. E., Lindqvist, A., Jaarsma, D., Flotho, A., Yu, K. L., Grigoriev, I., Engelsma, D., Haasdijk, E. D., Keijzer, N. et al. (2010). Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol. 8, 1000350.
-
(2010)
PLoS Biol
, vol.8
-
-
Splinter, D.1
Tanenbaum, M.E.2
Lindqvist, A.3
Jaarsma, D.4
Flotho, A.5
Yu, K.L.6
Grigoriev, I.7
Engelsma, D.8
Haasdijk, E.D.9
Keijzer, N.10
-
37
-
-
67649576600
-
Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1
-
Tibelius, A., Marhold, J., Zentgraf, H., Heilig, C. E., Neitzel, H., Ducommun, B., Rauch, A., Ho, A. D., Bartek, J. and Kramer, A. (2009). Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1. J. Cell Biol. 185, 1149-1157.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 1149-1157
-
-
Tibelius, A.1
Marhold, J.2
Zentgraf, H.3
Heilig, C.E.4
Neitzel, H.5
Ducommun, B.6
Rauch, A.7
Ho, A.D.8
Bartek, J.9
Kramer, A.10
-
38
-
-
67649253108
-
Chk1 Cterminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity
-
Walker, M., Black, E. J., Oehler, V., Gillespie, D. A. and Scott, M. T. (2009). Chk1 Cterminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene 28, 2314-2323.
-
(2009)
Oncogene
, vol.28
, pp. 2314-2323
-
-
Walker, M.1
Black, E.J.2
Oehler, V.3
Gillespie, D.A.4
Scott, M.T.5
-
39
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao, H. and Piwnica-Worms, H. (2001). ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell. Biol. 21, 4129-4139.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
40
-
-
0034707047
-
The DNA damage response: putting checkpoints in perspective
-
Zhou, B. B. and Elledge, S. J. (2000). The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
|