Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation

Biochemical and Biophysical Research Communications

Volumn 377, Issue 4, 2008, Pages 1227-1231

  Ikegami, Yosuke ^a,b   Goto, Hidemasa ^a   Kiyono, Tohru ^c   Enomoto, Masato ^a,d   Kasahara, Kousuke ^a   Tomono, Yasuko ^e   Tozawa, Keiichi ^b   Morita, Akimichi ^b   Kohri, Kenjiro ^b   Inagaki, Masaki ^a,d  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e Shigei Medical Research Institute   (Japan)

Author keywords

ATR; Checkpoint; Chk1; Cyclin dependent kinase 2 (Cdk2); Phosphorylation

Indexed keywords

ALANINE; ATR PROTEIN; CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; DNA; HYDROXYUREA; SERINE;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MITOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ULTRAVIOLET IRRADIATION;

DNA; DNA DAMAGE; DNA REPLICATION; HELA CELLS; HUMANS; HYDROXYUREA; IMMUNOPRECIPITATION; PHOSPHORYLATION; PROTEIN KINASES; SERINE; ULTRAVIOLET RAYS;

EID: 56349099694     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.119     Document Type: Article

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