Synthesis of new tetracyclic 7-oxo-pyrido[3,2,1-de]acridine derivatives

Tetrahedron

Volumn 67, Issue 33, 2011, Pages 5883-5893

  Chen, Ching Huang ^a   Lin, Yi Wen ^a   Kakadiya, Rajesh ^a   Kumar, Amit ^a   Chen, Yu Ting ^a   Lee, Te Chang ^a   Su, Tsann Long ^a,b  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Acridine; Acronycine; Cyclization; Eaton's reagent; Ullmann condensation

Indexed keywords

10 HYDROXY 4,5,6,11 TETRAMETHOXY 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 10 O ACETYL 4,5,6,11 TETRAMETHOXY 1,2 DIHYDROPYRIDO[3,2,1 DE]ACRIDINE 3,7 DIONE; 2 (7 METHOXY 4 OXO 3,4 DIHYDROQUINOLIN 1(2H) YL)BENZOIC ACID; 2,3 DIACETYL 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 2,3 DIACETYL 6 METHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 2,3 DIHYDROXY 3,4,5 TRIMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 2,3 DIHYDROXY 4,5,6,11 TETRAMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 2,3 DIHYDROXY 6 METHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 2,3,10 TRIHYDROXY 4,5,6,11 TETRAMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3 (1,2,3,5 TETRAMETHOXY 9 OXO 9H ACRIDIN 10 YL)PROPIONIC ACID; 3 (6 ACETOXY 1,2,3,5 TETRAMETHOXY 9 OXO 9H ACRIDIN 10 YL)PROPIONIC ACID; 3 (6 HYDROXY 1,2,3,5 TETRAMETHOXY 9 OXO 9H ACRIDIN 10 YL)PROPIONIC ACID; 3 ACETYL 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3 ACETYL 6 METHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3 HYDROXY 4,5,6 TRIMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3 HYDROXY 4,5,6,11 TETRAMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3 HYDROXY 6 METHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 3,10 DIHYDROXY 4,5,6,11 TETRAMETHOXY 2,3 DIHYDRO 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 4,5,6 TRIMETHOXY 1,2 DIHYDROPYRIDO[3,2,1 DE]ACRIDIN 3,7 DIONE; 4,5,6 TRIMETHOXY 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 4,5,6,11 TETRAMETHOXY 1,2 DIHYDROPYRIDO[3,2,1 DE]ACRIDINE 3,7 DIONE; 4,5,6,11 TETRAMETHOXY 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 6 METHOXY 1,2 DIHYDROPYRIDO[3,2,1 DE]ACRIDINE 3,7 DIONE; 6 METHOXY 1H PYRIDO[3,2,1 DE]ACRIDIN 7 ONE; 7 OXO PYRIDO[3,2,1 DE]ACRIDINE DERIVATIVE; ACID ANHYDRIDE; ACRIDINE DERIVATIVE; PROPIONIC ACID DERIVATIVE; PYRIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CYCLIZATION; CYTOTOXICITY; DIHYDROXYLATION; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LYMPHATIC LEUKEMIA; PRIORITY JOURNAL;

EID: 79960261361     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.06.062     Document Type: Article

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