Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1

Biochemical Pharmacology

Volumn 63, Issue 8, 2002, Pages 1443-1452

  Kluza, Jérôme ^a   Lansiaux, Amélie ^a   Wattez, Nicole ^a   Hildebrand, Marie Paule ^a   Léonce, Stéphane ^b   Pierré, Alain ^b   Hickman, John A ^b   Bailly, Christian ^a  

^a INSERM   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Acronycine; Anticancer drug; Apoptosis; Caspases; Cell cycle; Mitochondria; S23906 1

Indexed keywords

1,2 DIACETOXY 1,2 DIHYDROBENZOACRONYCINE; ACRIDINE ORANGE; ACRONINE; ANTINEOPLASTIC AGENT; CARDIOLIPIN; CASPASE 3; FLUOROCHROME; LIPOCORTIN 5; REACTIVE OXYGEN METABOLITE; S 23906 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CANCER CELL CULTURE; CELL CYCLE; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MELANOMA; MELANOMA CELL; MITOCHONDRION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DNA INTERACTION; SOLID TUMOR; SPECTRUM; TUMOR XENOGRAFT;

ACRONINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL CYCLE; CELL MEMBRANE; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; LEUKEMIA; MELANOMA, EXPERIMENTAL; MEMBRANE POTENTIALS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 0037090938     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00899-7     Document Type: Article

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