Chiral dihydroxylation of acronycine: Absolute configuration of natural cis-1,2-dihydroxy-1,2-dihydroacronycine and cytotoxicity of (1R,2R)- and (1S,2S)-1,2-diacetoxy-1,2-dihydroacronycine

Journal of Natural Products

Volumn 62, Issue 3, 1999, Pages 490-492

  Costes, Nadine ^a   Michel, Sylvie ^a   Tillequin, François ^a   Koch, Michel ^a   Pierré, Alain ^b   Atassi, Ghanem ^b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIACETOXY 1,2 DIHYDROACRONYCINE; ACRONINE; ANTINEOPLASTIC ALKALOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHIRALITY; DRUG CONFORMATION; DRUG CYTOTOXICITY; ENANTIOMER; LEUKEMIA L 1210; MOUSE; NONHUMAN;

ACRONINE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; HYDROXYLATION; INHIBITORY CONCENTRATION 50; LEUKEMIA L1210; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0032916316     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np980420q     Document Type: Article

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