Synthesis and cytotoxic and antitumor activity of benzo[b]pyrano[3,2- h]acridin-7-one analogues of acronycine

Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2000, Pages 2395-2402

  Costes, Nadine ^a   Le Deit, Hervé ^a   Michel, Sylvie ^a   Tillequin, François ^a   Koch, Michel ^a   Pfeiffer, Bruno ^b   Renard, Pierre ^b   Léonce, Stéphane ^c   Guilbaud, Nicolas ^c   Kraus Berthier, Laurence ^c   Pierré, Alain ^c   Atassi, Ghanem ^c  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b ADIR   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DI O CARBONYL 1,2 DIHYDROXY 6 METHOXY 3,3,14 TRIMETHYL 1,2,3,14 TETRAHYDRO 7H BENZO[B]PYRANO[3,2 H]ACRIDIN 7 ONE; 1,2 DIACETOXY 6 METHOXY 3,3,14 TRIMETHYL 1,2,3,14 TETRAHYDRO 7H BENZO[B]PYRANO[3,2 H]ACRIDIN 7 ONE; ACRONINE; ACRONINE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ESTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL CYCLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; TUMOR;

ACRIDINES; ACRONINE; ANIMALS; ANTINEOPLASTIC AGENTS; BENZOPYRANS; DNA, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; MICE; NEOPLASM TRANSPLANTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033945548     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990972l     Document Type: Article

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