Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism

Cell Death and Differentiation

Volumn 18, Issue 8, 2011, Pages 1356-1365

  Hagen, N ^a   Hans, M ^a   Hartmann, D ^a   Swandulla, D ^a   Van Echten Deckert, G ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

apoptosis; Ca 2+ release; calpain; cis 4 methylsphingosine; neurodegeneration; Sphingosine 1 phosphate

Indexed keywords

CALPAIN; CASPASE; CYCLIN DEPENDENT KINASE 5; GLYCOSPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; TAU PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE REGULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOPLASMIC RETICULUM STRESS; LIPID METABOLISM; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROANATOMY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALDEHYDE-LYASES; ANIMALS; APOPTOSIS; CALCIUM; CALPAIN; CASPASE 12; CASPASE 9; CELL CYCLE; CEREBELLUM; CYCLIN-DEPENDENT KINASE 5; GLYCOSPHINGOLIPIDS; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NERVE DEGENERATION; NEURONS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SIGNAL TRANSDUCTION; SPHINGOSINE; TAU PROTEINS;

MUS; SPHINGOIDEA;

EID: 79960204590     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.7     Document Type: Article

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