Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes

Neuroscience

Volumn 94, Issue 2, 1999, Pages 405-415

  Moore, A N ^a   Kampfl, A W ^b   Zhao, X ^c   Hayes, R L ^c   Dash, P K ^a  

^a W M Keck Ctr Neurbio Lrng M   (United States)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

AP 1 complexes; c Fos; Calcineurin; Caspase; Phosphatases; TRE sequence

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTISENSE OLIGONUCLEOTIDE; CALCINEURIN; CERAMIDE; CYANOGINOSIN LR; CYCLOSPORIN A; METALLOTHIONEIN; OKADAIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; SPHINGOSINE 1 PHOSPHATE; TACROLIMUS; TRANSCRIPTION FACTOR AP 1;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; DEPHOSPHORYLATION; FETUS; HIPPOCAMPUS; IMMUNOREACTIVITY; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; FETUS; GENES, FOS; GENES, JUN; HIPPOCAMPUS; KINETICS; LYSOPHOSPHOLIPIDS; NEURONS; OLIGODEOXYRIBONUCLEOTIDES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PHOSPHOPROTEIN PHOSPHATASE; RATS; REGULATORY SEQUENCES, NUCLEIC ACID; SPHINGOSINE; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

EID: 0032835097     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00288-2     Document Type: Article

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