Hyperpolarizing inhibition develops without trophic support by GABA in cultured rat midbrain neurons

Journal of Physiology

Volumn 550, Issue 3, 2003, Pages 719-730

  Titz, Stefan ^a   Hans, Michael ^b   Kelsch, Wolfgang ^a   Lewen, Andrea ^a   Swandulla, Dieter ^b   Misgeld, Ulrich ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM ION; CHLORIDE ION; POTASSIUM ION; CHLORIDE; GRAMICIDIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CHLORIDE CURRENT; CHLORIDE TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ELECTRIC POTENTIAL; EMBRYO; GABAERGIC TRANSMISSION; HYPERPOLARIZATION; HYPOTHESIS; MESENCEPHALON; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; TROPHIC LEVEL; BRAIN DEVELOPMENT; CALCIUM TRANSPORT; CELL TRANSPORT; DEPOLARIZATION; FEMALE; GABAERGIC SYSTEM; PERFORATED PATCH CLAMP; POTASSIUM TRANSPORT; RECEPTOR BLOCKING; SYNAPTIC POTENTIAL;

ANIMALS; CALCIUM SIGNALING; CELLS, CULTURED; CHLORIDE CHANNELS; ELECTROPHYSIOLOGY; FEMALE; FLUORESCENT DYES; FURA-2; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GRAMICIDIN; MESENCEPHALON; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHLORIDE; PREGNANCY; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SYNAPSES;

EID: 0041474565     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.041863     Document Type: Article

References (53)

1. Abe Y, Furukawa K, Itoyama Y & Akaike N (1994). Glycine response in acutely dissociated ventromedial hypothalamic neuron of the rat: new approach with gramicidin perforated patch-clamp technique. J Neurophysiol 72, 1530-1537.
2. Barker JL, Behar T, Li YX, Liu QY, Ma W, Maric D, Maric I, Schaffner AE, Serafini R, Smith SV, Somogyi R, Vautrin JY, Wen XL & Xian H (1998). GABAergic cells and signals in CNS development. Perspect Dev Neurobiol 5, 305-322.
3. Ben-Ari Y, Cherubini E, Corradetti R & Gaiarsa J-L (1989). Giant synaptic potentials in immature rat CA3 hippocampal neurones. J Physiol 416, 303-325.
4. Bormann J, Hamill OP & Sakmann B (1987). Mechanism of anion permeation through channels gated by glycine and γ-aminobutyric acid in mouse cultured spinal neurones. J Physiol 385, 243-286.
5. Chen G, Trombley PQ & van den Pol AN (1996). Excitatory actions of GABA in developing rat hypothalamic neurones. J Physiol 494, 451-464.
6. Choi DW (1992). Excitotoxic cell death. J Neurobiol 23, 1261-1276.
7. - cotransporter expression in rat neocortex. Develop Brain Res 109, 281-292.
8. Delpire E (2000). Cation-chloride cotransporters in neuronal communication. News Physiol Sci 15, 309-312.
9. Ebihara S, Shirato K, Harata N & Akaike N (1995). Gramicidin-perforated patch recording: GABA response in mammalian neurones with intact intracellular chloride. J Physiol 484, 77-86.
10. 2+ signalling in developing rat cerebellar Purkinje neurones. J Physiol 536, 429-437.
11. Ganguly K, Schinder AF, Wong ST & Poo M (2001). GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 105, 521-532.
12. Garaschuk O, Hanse E & Konnerth A (1998). Developmental profile and synaptic origin of early network oscillations in the CA1 region of rat neonatal hippocampus. J Physiol 507, 219-236.
13. Hübner CA, Lorke DE & Hermans-Borgmeyer I (2001a). Expression of the Na-K-2Cl-cotransporter NKCC1 during mouse development. Mech Dev 102, 267-269.
14. Hübner CA, Stein V, Hermans-Borgmeyer I, Meyer T, Ballanyi K & Jentsch TJ (2001b). Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Neuron 30, 515-524.
15. A receptor-mediated presynaptic depolarization in excitatory nerve terminals. J Neurosci 21, 5962-5972.
16. - accumulation and depletion in cultured rat midbrain neurons. J Neurosci 19, 4695-4704.
17. Jarolimek W & Misgeld U (1992). On the inhibitory actions of baclofen and γ-aminobutyric acid in rat ventral midbrain culture. J Physiol 451, 419-443.
18. B receptor-mediated inhibition of tetrodotoxin-resistant GABA release in rodent hippocampal CA1 pyramidal cells. J Neurosci 17, 1025-1032.
19. A receptor- mediated IPSPs of rat neocortical neurones. J Physiol 464, 273-289.
20. Kakazu Y, Akaike N, Komiyama S & Nabekura I (1999). Regulation of intracellular chloride by cotransporters in developing lateral superior olive neurons. J Neurosci 19, 2843-2851.
21. Kelsch W, Hormuzdi S, Straube E, Lewen A, Monyer H & Misgeld U (2001). Insulin-like growth factor 1 and a cytosolic tyrosine kinase activate chloride outward transport during maturation of hippocampal neurons. J Neurosci 21, 8339-8347.
22. Kennedy RT, Thompson JE & Vickroy TW (2002). In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis. J Neurosci Meth 114, 39-49.
23. Kneussel M & Betz H (2000). Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: the membrane activation model. Trends Neurosci 23, 429-435.
24. Kobayashi S, Morgans CW, Casey JR & Kopito RR (1994). AE3 anion exchanger isoforms in the vertebrate retina: developmental regulation and differential expression in neurons and glia. J Neurosci 14, 6266-6279.
25. 2+ channel activator, FPL 64176, in GH3 cells. Mol Pharmacol 42, 666-670.
26. Kyrozis A & Reichling DB (1995). Perforated-patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration. J Neurosci Meth 57, 27-35.
27. A activation inhibits AMPA-kainate receptor-mediated bursting in the newborn (P0-P2) rat hippocampus. J Neurophysiol 83, 359-366.
28. 2+ rise in pyramidal cells and interneurons from rat neonatal hippocampal slices. J Physiol 487, 319-329.
29. Lerma J, Herranz AS, Herreras O, Abraira V & Martín Del Río R (1986). In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis. Brain Res 384, 145-155.
30. Li Y-X, Schaffner AE, Walton MK & Barker JL (1998). Astrocytes regulate developmental changes in the chloride ion gradient of embryonic rat ventral spinal cord neurons in culture. J Physiol 509, 847-858.
31. Lipton SA & Kater SB (1989). Neurotransmitter regulation of neuronal outgrowth, plasticity and survival. Trends Neurosci 12, 265-270.
32. LoTurco JJ, Owens DF, Heath MjS, Davies MBE & Kriegstein AR (1995). GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis. Neuron 15, 1287-1298.
33. - channels. J Neurosci 21, 2343-2360.
34. Marty S, Berninger B, Carroll P & Thoenen H (1996). GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron 16, 565-570.
35. - cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysis. Eur J Neurosci 15, 233-245.
36. Misgeld U, Deisz RA, Dodt HU & Lux HD (1986). The role of chloride transport in postsynaptic inhibition of hippocampal neurons. Science 232, 1413-1415.
37. 2+ elevating to depressing. J Neurosci 15, 5065-5077.
38. Obrietan K & van den Pol AN (1996). Growth cone calcium elevation by GABA. J Comp Neurol 372, 167-175.
39. Owens DF, Boyce LH, Davis MBE & Kriegstein AR (1996). Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging. J Neurosci 16, 6414-6423.
40. Payne JA, Stevenson TJ & Donaldson LF (1996). Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform. J Biol Chem 271, 16245-16252.
41. Plotkin MD, Snyder EY, Hebert SC & Delpire E (1997). Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain. J Neurobiol 33, 781-795.
42. Reichling DB, Kyrozis A, Wang J & MacDermott AB (1994). Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons. J Physiol 476, 411-421.
43. - co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature 397, 251-255.
44. A receptor antagonists in rat embryonic midbrain culture. J Neurophysiol 79, 1113-1116.
45. A receptor-mediated responses in spinal neurons. J Neurosci 16, 82-91.
46. Smith RL, Clayton GH, Wilcox CL, Escudero KW & Staley KJ (1995). Differential expression of an inwardly rectifying chloride conductance in rat brain neurons: a potential mechanism for cell-specific modulation of postsynaptic inhibition. J Neurosci 15, 4057-4067.
47. - regulation. J Neurophysiol 81, 1939-1948.
48. A receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice. J Neurosci 20, 7531-7538.
49. Tossman U, Jonsson G & Ungerstedt U (1986). Regional distribution and extracellular levels of amino acids in rat central nervous system. Acta Physiol Scand 127, 533-545.
50. van den Pol AN, Obrietan K & Chen G (1996). Excitatory actions of GABA after neuronal trauma. J Neurosci 16, 4283-4292.
51. Vardi N, Zhang L-L, Payne JA & Sterling P (2000). Evidence that different cation chloride cotransporters in retinal neurons allow opposite responses to GABA. J Neurosci 20, 7657-7663.
52. - cotransporter in rat brain during development and its localization in mature astrocytes. Brain Res 911, 43-55.
53. 2+ influx in developing neocortex by excitatory and inhibitory neurotransmitters. Neuron 6, 333-344.