Does sex matter? the influence of gender on gastrointestinal physiology and drug delivery

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 15-28

  Freire, Ana C ^a   Basit, Abdul W ^a   Choudhary, Rahul ^a   Piong, Chee W ^a   Merchant, Hamid A ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Absorption; Bioavailability; Colon; Fluids; Gastrointestinal physiology; Microbiota; Motility; Personalized medicines; pH; Pharmacokinetics; Population variability; Small intestine; Stomach; Transit

Indexed keywords

ALCOHOL DEHYDROGENASE; CLARITHROMYCIN; CYTOCHROME P450; DIGOXIN; EXCIPIENT; GLUTATHIONE TRANSFERASE; MIDAZOLAM; NORVERAPAMIL; VERAPAMIL;

DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG METABOLISM; ENZYME ACTIVITY; FOOD; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT FUNCTION; HUMAN; KIDNEY FUNCTION; LARGE INTESTINE; LIVER FUNCTION; MENSTRUAL CYCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SEX DIFFERENCE; SMALL INTESTINE; STOMACH EMPTYING; STOMACH PH; SUSTAINED DRUG RELEASE; UPREGULATION;

BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; FEMALE; GASTROINTESTINAL TRACT; HUMANS; INDIVIDUALIZED MEDICINE; MALE; PHARMACEUTICAL PREPARATIONS; SEX CHARACTERISTICS;

EID: 79960177999     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.069     Document Type: Review

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