-
1
-
-
0037379385
-
From genes to integrative physiology: Ion channel and transporter biology in Caenorhabditis elegans
-
Strange, K., (2003) From genes to integrative physiology: ion channel and transporter biology in Caenorhabditis elegans. Physiological Reviews, 83, 377-415. (Pubitemid 36378676)
-
(2003)
Physiological Reviews
, vol.83
, Issue.2
, pp. 377-415
-
-
Strange, K.1
-
2
-
-
2942650969
-
Adipose tissue as an endocrine organ
-
DOI 10.1210/jc.2004-0395
-
Kershaw, E.E., &, Flier, J.S., (2004) Adipose tissue as an endocrine organ. Journal of Clinical Endocrinology and Metabolism, 89, 2548-2556. (Pubitemid 38766330)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.6
, pp. 2548-2556
-
-
Kershaw, E.E.1
Flier, J.S.2
-
3
-
-
1442327902
-
Adipocytokines and Insulin Resistance
-
DOI 10.1210/jc.2003-031005
-
Pittas, A.G., Joseph, N.A., &, Greenberg, A.S., (2004) Adipocytokines and insulin resistance. Journal of Clinical Endocrinology and Metabolism, 89, 447-452. (Pubitemid 38269842)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.2
, pp. 447-452
-
-
Pittas, A.G.1
Joseph, N.A.2
Greenberg, A.S.3
-
4
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy, P., Amling, M., Takeda, S., et al. (2000) Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell, 100, 197-207. (Pubitemid 30064908)
-
(2000)
Cell
, vol.100
, Issue.2
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
Shen, J.7
Vinson, C.8
Rueger, J.M.9
Karsenty, G.10
-
5
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
DOI 10.1038/nature03398
-
Elefteriou, F., Ahn, J.D., Takeda, S., et al. (2005) Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature, 434, 514-520. (Pubitemid 40477060)
-
(2005)
Nature
, vol.434
, Issue.7032
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
Clement, K.11
Valsse, C.12
Karsenty, G.13
-
6
-
-
12144288193
-
Serum leptin level is a regulator of bone mass
-
DOI 10.1073/pnas.0308744101
-
Elefteriou, F., Takeda, S., Ebihara, K., et al. (2004) Serum leptin level is a regulator of bone mass. Proceedings of the National Academy of Sciences of the United States of America, 101, 3258-3263. (Pubitemid 38327768)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.9
, pp. 3258-3263
-
-
Elefteriou, F.1
Takeda, S.2
Ebihara, K.3
Magre, J.4
Patano, N.5
Kim, C.A.6
Ogawa, Y.7
Liu, X.8
Ware, S.M.9
Craigen, W.J.10
Robert, J.J.11
Vinson, C.12
Nakao, K.13
Capeau, J.14
Karsenty, G.15
-
7
-
-
58149498221
-
Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo
-
et al.
-
Shi, Y., Yadav, V.K., Suda, N., et al. (2008) Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proceedings of the National Academy of Sciences of the United States of America, 105, 20529-20533.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 20529-20533
-
-
Shi, Y.1
Yadav, V.K.2
Suda, N.3
-
8
-
-
47949114080
-
Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule
-
Singh, M.K., Elefteriou, F., &, Karsenty, G., (2008) Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule. Endocrinology, 149, 3933-3941.
-
(2008)
Endocrinology
, vol.149
, pp. 3933-3941
-
-
Singh, M.K.1
Elefteriou, F.2
Karsenty, G.3
-
9
-
-
33750453786
-
Convergence between bone and energy homeostases: Leptin regulation of bone mass
-
DOI 10.1016/j.cmet.2006.10.008, PII S1550413106003378
-
Karsenty, G., (2006) Convergence between bone and energy homeostases: leptin regulation of bone mass. Cell Metabolism, 4, 341-348. (Pubitemid 44645074)
-
(2006)
Cell Metabolism
, vol.4
, Issue.5
, pp. 341-348
-
-
Karsenty, G.1
-
10
-
-
18744376564
-
Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo
-
DOI 10.1677/joe.0.1750405
-
Cornish, J., Callon, K.E., Bava, U., et al. (2002) Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo. Journal of Endocrinology, 175, 405-415. (Pubitemid 35414387)
-
(2002)
Journal of Endocrinology
, vol.175
, Issue.2
, pp. 405-415
-
-
Cornish, J.1
Callon, K.E.2
Bava, U.3
Lin, C.4
Naot, D.5
Hill, B.L.6
Grey, A.B.7
Broom, N.8
Myers, D.E.9
Nicholson, G.C.10
Reid, I.R.11
-
11
-
-
0036150527
-
Leptin inhibits osteoclast generation
-
Holloway, W.R., Collier, F.M., Aitken, C.J., et al. (2002) Leptin inhibits osteoclast generation. Journal of Bone and Mineral Research, 17, 200-209. (Pubitemid 34087652)
-
(2002)
Journal of Bone and Mineral Research
, vol.17
, Issue.2
, pp. 200-209
-
-
Holloway, W.R.1
Collier, F.Mc.L.2
Aitken, C.J.3
Myers, D.E.4
Hodge, J.M.5
Malakellis, M.6
Gough, T.J.7
Collier, G.R.8
Nicholson, G.C.9
-
12
-
-
1542331341
-
Beta-Adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong osteoporosis study
-
DOI 10.1359/JBMR.0301214
-
Pasco, J.A., Henry, M.J., Sanders, K.M., et al. (2004) Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study. Journal of Bone and Mineral Research, 19, 19-24. (Pubitemid 41295133)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.1
, pp. 19-24
-
-
Pasco, J.A.1
Henry, M.J.2
Sanders, K.M.3
Kotowicz, M.A.4
Seeman, E.5
Nicholson, G.C.6
-
13
-
-
4544350596
-
Use of beta-blockers and risk of fractures
-
et al.
-
Schlienger, R.G., Kraenzlin, M.E., Jick, S.S., et al. (2004) Use of beta-blockers and risk of fractures. JAMA, 292, 1326-1332.
-
(2004)
JAMA
, vol.292
, pp. 1326-1332
-
-
Schlienger, R.G.1
Kraenzlin, M.E.2
Jick, S.S.3
-
14
-
-
15344344530
-
Beta-blocker use, BMD, and fractures in the study of osteoporotic fractures
-
DOI 10.1359/JBMR.041202
-
Reid, I.R., Gamble, G.D., Grey, A.B., et al. (2005) beta-Blocker use, BMD, and fractures in the study of osteoporotic fractures. Journal of Bone and Mineral Research, 20, 613-618. (Pubitemid 40393069)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.4
, pp. 613-618
-
-
Reid, I.R.1
Gamble, G.D.2
Grey, A.B.3
Black, D.M.4
Ensrud, K.E.5
Browner, W.S.6
Bauer, D.C.7
-
15
-
-
34547690686
-
Endocrine Regulation of Energy Metabolism by the Skeleton
-
DOI 10.1016/j.cell.2007.05.047, PII S0092867407007015
-
Lee, N.K., Sowa, H., Hinoi, E., et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell, 130, 456-469. (Pubitemid 47208519)
-
(2007)
Cell
, vol.130
, Issue.3
, pp. 456-469
-
-
Lee, N.K.1
Sowa, H.2
Hinoi, E.3
Ferron, M.4
Ahn, J.D.5
Confavreux, C.6
Dacquin, R.7
Mee, P.J.8
McKee, M.D.9
Jung, D.Y.10
Zhang, Z.11
Kim, J.K.12
Mauvais-Jarvis, F.13
Ducy, P.14
Karsenty, G.15
-
16
-
-
0028072616
-
Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation
-
Mauro, L.J., Olmsted, E.A., Skrobacz, B.M., et al. (1994) Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation. The Journal of Biological Chemistry, 269, 30659-30667. (Pubitemid 24376554)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.48
, pp. 30659-30667
-
-
Mauro, L.J.1
Olmsted, E.A.2
Skrobacz, B.M.3
Mourey, R.J.4
Davis, A.R.5
Dixon, J.E.6
-
17
-
-
1842457067
-
Knock-In of Nuclear Localised beta-Galactosidase Reveals that the Tyrosine Phosphatase Ptprv Is Specifically Expressed in Cells of the Bone Collar
-
DOI 10.1002/dvdy.20003
-
Dacquin, R., Mee, P.J., Kawaguchi, J., et al. (2004) Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Developmental Dynamics, 229, 826-834. (Pubitemid 38429111)
-
(2004)
Developmental Dynamics
, vol.229
, Issue.4
, pp. 826-834
-
-
Dacquin, R.1
Mee, P.J.2
Kawaguchi, J.3
Olmsted-Davis, E.A.4
Gallagher, J.A.5
Nichols, J.6
Lee, K.7
Karsenty, G.8
Smith, A.9
-
18
-
-
59449093033
-
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity
-
et al.
-
Hinoi, E., Gao, N., Jung, D.Y., et al. (2008) The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. Journal of Cell Biology, 183, 1235-1242.
-
(2008)
Journal of Cell Biology
, vol.183
, pp. 1235-1242
-
-
Hinoi, E.1
Gao, N.2
Jung, D.Y.3
-
19
-
-
67651237067
-
Mechanisms of exercise-induced mitochondrial biogenesis in skeletal muscle
-
Hood, D.A., (2009) Mechanisms of exercise-induced mitochondrial biogenesis in skeletal muscle. Applied Physiology, Nutrition, and Metabolism, 34, 465-472.
-
(2009)
Applied Physiology, Nutrition, and Metabolism
, vol.34
, pp. 465-472
-
-
Hood, D.A.1
-
20
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
DOI 10.1210/er.2005-0005
-
Kadowaki, T., &, Yamauchi, T., (2005) Adiponectin and adiponectin receptors. Endocrine Reviews, 26, 439-451. (Pubitemid 40686653)
-
(2005)
Endocrine Reviews
, vol.26
, Issue.3
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
21
-
-
0024370924
-
Osteocalcin and matrix Gla protein: Vitamin K-dependent proteins in bone
-
Hauschka, P.V., Lian, J.B., Cole, D.E., et al. (1989) Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. Physiological Reviews, 69, 990-1047. (Pubitemid 19184853)
-
(1989)
Physiological Reviews
, vol.69
, Issue.3
, pp. 990-1047
-
-
Hauschka, P.V.1
Lian, J.B.2
Cole, D.E.3
Gundberg, C.M.4
-
22
-
-
0024820519
-
Gla-containing proteins of bone
-
discussion 57-60.
-
Price, P.A., (1989) Gla-containing proteins of bone. Connective Tissue Research, 21, 51-57; discussion 57-60.
-
(1989)
Connective Tissue Research
, vol.21
, pp. 51-57
-
-
Price, P.A.1
-
23
-
-
15844412402
-
Increased bone formation in osteocalcin-deficient mice
-
DOI 10.1038/382448a0
-
Ducy, P., Desbois, C., Boyce, B., et al. (1996) Increased bone formation in osteocalcin-deficient mice. Nature, 382, 448-452. (Pubitemid 26264860)
-
(1996)
Nature
, vol.382
, Issue.6590
, pp. 448-452
-
-
Ducy, P.1
Desbois, C.2
Boyce, B.3
Pinero, G.4
Story, B.5
Dunstan, C.6
Smith, E.7
Bonadio, J.8
Goldstein, S.9
Gundberg, C.10
Bradley, A.11
Karsenty, G.12
-
24
-
-
42449096306
-
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
-
DOI 10.1073/pnas.0711119105
-
Ferron, M., Hinoi, E., Karsenty, G., et al. (2008) Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proceedings of the National Academy of Sciences of the United States of America, 105, 5266-5270. (Pubitemid 351738545)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.13
, pp. 5266-5270
-
-
Ferron, M.1
Hinoi, E.2
Karsenty, G.3
Ducy, P.4
-
25
-
-
77956555175
-
Integrative physiology: Defined novel metabolic roles of osteocalcin
-
et al.
-
Kim, Y.S., Paik, I.Y., Rhie, Y.J., et al. (2010) Integrative physiology: defined novel metabolic roles of osteocalcin. Journal of Korean Medical Science, 25, 985-991.
-
(2010)
Journal of Korean Medical Science
, vol.25
, pp. 985-991
-
-
Kim, Y.S.1
Paik, I.Y.2
Rhie, Y.J.3
-
26
-
-
0021967944
-
Characterization of the effect of insulin on collagen synthesis in fetal rat bone
-
Kream, B.E., Smith, M.D., Canalis, E., et al. (1985) Characterization of the effect of insulin on collagen synthesis in fetal rat bone. Endocrinology, 116, 296-302. (Pubitemid 15190482)
-
(1985)
Endocrinology
, vol.116
, Issue.1
, pp. 296-302
-
-
Kream, B.E.1
Smith, M.D.2
Canalis, E.3
Raisz, L.G.4
-
27
-
-
0024851161
-
The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line
-
Pun, K.K., Lau, P., &, Ho, P.W., (1989) The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line. Journal of Bone and Mineral Research, 4, 853-862. (Pubitemid 20065695)
-
(1989)
Journal of Bone and Mineral Research
, vol.4
, Issue.6
, pp. 853-862
-
-
Pun, K.K.1
Lau, P.2
Ho, P.W.M.3
-
28
-
-
0024347904
-
Glucose transport system in UMR-106-01 osteoblastic osteosarcoma cells: Regulation by insulin
-
Ituarte, E.A., Halstead, L.R., Iida-Klein, A., et al. (1989) Glucose transport system in UMR-106-01 osteoblastic osteosarcoma cells: regulation by insulin. Calcified Tissue International, 45, 27-33. (Pubitemid 19166468)
-
(1989)
Calcified Tissue International
, vol.45
, Issue.1
, pp. 27-33
-
-
Ituarte, E.A.1
Halstead, L.R.2
Iida-Klein, A.3
Ituarte, H.G.4
Hahn, T.J.5
-
29
-
-
24944574404
-
The effects of local insulin delivery on diabetic fracture healing
-
DOI 10.1016/j.bone.2005.04.039, PII S8756328205002139
-
Gandhi, A., Beam, H.A., O'Connor, J.P., et al. (2005) The effects of local insulin delivery on diabetic fracture healing. Bone, 37, 482-490. (Pubitemid 41317321)
-
(2005)
Bone
, vol.37
, Issue.4
, pp. 482-490
-
-
Gandhi, A.1
Beam, H.A.2
O'Connor, J.P.3
Parsons, J.R.4
Lin, S.S.5
-
30
-
-
33845883071
-
Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice
-
DOI 10.1210/en.2006-1006
-
Botolin, S., &, McCabe, L.R., (2007) Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice. Endocrinology, 148, 198-205. (Pubitemid 46021451)
-
(2007)
Endocrinology
, vol.148
, Issue.1
, pp. 198-205
-
-
Botolin, S.1
McCabe, L.R.2
-
31
-
-
34547579253
-
Type I diabetic bone phenotype is location but not gender dependent
-
DOI 10.1007/s00418-007-0308-4
-
Martin, L.M., &, McCabe, L.R., (2007) Type I diabetic bone phenotype is location but not gender dependent. Histochemistry and Cell Biology, 128, 125-133. (Pubitemid 47197932)
-
(2007)
Histochemistry and Cell Biology
, vol.128
, Issue.2
, pp. 125-133
-
-
Martin, L.M.1
McCabe, L.R.2
-
32
-
-
77955035304
-
Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
-
et al.
-
Ferron, M., Wei, J., Yoshizawa, T., et al. (2010) Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell, 142, 296-308.
-
(2010)
Cell
, vol.142
, pp. 296-308
-
-
Ferron, M.1
Wei, J.2
Yoshizawa, T.3
-
33
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J., (2000) Cell signaling by receptor tyrosine kinases. Cell, 103, 211-225.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
34
-
-
0029810614
-
Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling
-
et al.
-
Kenner, K.A., Anyanwu, E., Olefsky, J.M., et al. (1996) Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling. The Journal of Biological Chemistry, 271, 19810-19816.
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 19810-19816
-
-
Kenner, K.A.1
Anyanwu, E.2
Olefsky, J.M.3
-
35
-
-
62749115187
-
Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress
-
et al.
-
Delibegovic, M., Zimmer, D., Kauffman, C., et al. (2009) Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress. Diabetes, 58, 590-599.
-
(2009)
Diabetes
, vol.58
, pp. 590-599
-
-
Delibegovic, M.1
Zimmer, D.2
Kauffman, C.3
-
36
-
-
77955082747
-
Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
-
et al.
-
Fulzele, K., Riddle, R.C., DiGirolamo, D.J., et al. (2010) Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell, 142, 309-319.
-
(2010)
Cell
, vol.142
, pp. 309-319
-
-
Fulzele, K.1
Riddle, R.C.2
Digirolamo, D.J.3
-
37
-
-
12144288066
-
A twist code determines the onset of osteoblast differentiation
-
DOI 10.1016/S1534-5807(04)00058-9, PII S1534580704000589
-
Bialek, P., Kern, B., Yang, X., et al. (2004) A twist code determines the onset of osteoblast differentiation. Developmental Cell, 6, 423-435. (Pubitemid 38364573)
-
(2004)
Developmental Cell
, vol.6
, Issue.3
, pp. 423-435
-
-
Bialek, P.1
Kern, B.2
Yang, X.3
Schrock, M.4
Sosic, D.5
Hong, N.6
Wu, H.7
Yu, K.8
Ornitz, D.M.9
Olson, E.N.10
Justice, M.J.11
Karsenty, G.12
-
38
-
-
74949089660
-
FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice
-
et al.
-
Rached, M.T., Kode, A., Silva, B.C., et al. (2010) FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice. Journal of Clinical Investigation, 120, 357-368.
-
(2010)
Journal of Clinical Investigation
, vol.120
, pp. 357-368
-
-
Rached, M.T.1
Kode, A.2
Silva, B.C.3
-
39
-
-
0036787607
-
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
-
et al.
-
Nakae, J., Biggs III, W.H., Kitamura, T., et al. (2002) Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nature Genetics, 32, 245-253.
-
(2002)
Nature Genetics
, vol.32
, pp. 245-253
-
-
Nakae, J.1
Biggs Iii, W.H.2
Kitamura, T.3
-
40
-
-
0025761821
-
Vitamin K-dependent carboxylase: Utilization of decarboxylated bone Gla protein and matrix Gla protein as substrates
-
et al.
-
Engelke, J.A., Hale, J.E., Suttie, J.W., et al. (1991) Vitamin K-dependent carboxylase: utilization of decarboxylated bone Gla protein and matrix Gla protein as substrates. Biochimica et Biophysica Acta, 1078, 31-34.
-
(1991)
Biochimica et Biophysica Acta
, vol.1078
, pp. 31-34
-
-
Engelke, J.A.1
Hale, J.E.2
Suttie, J.W.3
-
41
-
-
30744432094
-
The role of chloride channels in osteoclasts: ClC-7 as a target for osteoporosis treatment
-
DOI 10.1358/dnp.2005.18.8.944546
-
Schaller, S., Henriksen, K., Sorensen, M.G., et al. (2005) The role of chloride channels in osteoclasts: ClC-7 as a target for osteoporosis treatment. Drug News & Perspectives, 18, 489-495. (Pubitemid 43094116)
-
(2005)
Drug News and Perspectives
, vol.18
, Issue.8
, pp. 489-495
-
-
Schaller, S.1
Henriksen, K.2
Sorensen, M.G.3
Karsdal, M.A.4
-
42
-
-
45349084061
-
Reciprocal regulation of bone and energy metabolism
-
DOI 10.1016/j.tem.2008.02.006, PII S1043276008000593
-
Lee, N.K., &, Karsenty, G., (2008) Reciprocal regulation of bone and energy metabolism. Trends in Endocrinology and Metabolism, 19, 161-166. (Pubitemid 351847838)
-
(2008)
Trends in Endocrinology and Metabolism
, vol.19
, Issue.5
, pp. 161-166
-
-
Lee, N.K.1
Karsenty, G.2
-
43
-
-
0347721834
-
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization
-
DOI 10.1074/jbc.M208265200
-
Zhang, M., Xuan, S., Bouxsein, M.L., et al. (2002) Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. The Journal of Biological Chemistry, 277, 44005-44012. (Pubitemid 36157826)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 44005-44012
-
-
Zhang, M.1
Xuan, S.2
Bouxsein, M.L.3
Von Stechow, D.4
Akeno, N.5
Faugere, M.C.6
Malluche, H.7
Zhao, G.8
Rosen, C.J.9
Efstratiadis, A.10
Clemens, T.L.11
-
44
-
-
70350435713
-
An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion
-
et al., ().
-
Hinoi, E., Gao, N., Jung, D.Y., et al. (2009) An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion. Annals of the New York Academy of Sciences, 1173 (Suppl 1), E20-30.
-
(2009)
Annals of the New York Academy of Sciences
, vol.1173
, Issue.SUPPL. 1
-
-
Hinoi, E.1
Gao, N.2
Jung, D.Y.3
-
45
-
-
3543044984
-
Cloning of hOST-PTP: The only example of a protein-tyrosine-phosphatase the function of which has been lost between rodent and human
-
DOI 10.1016/j.bbrc.2004.06.137, PII S0006291X04013737
-
Cousin, W., Courseaux, A., Ladoux, A., et al. (2004) Cloning of hOST-PTP: the only example of a protein-tyrosine-phosphatase the function of which has been lost between rodent and human. Biochemical and Biophysical Research Communications, 321, 259-265. (Pubitemid 39055633)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.321
, Issue.1
, pp. 259-265
-
-
Cousin, W.1
Courseaux, A.2
Ladoux, A.3
Dani, C.4
Peraldi, P.5
-
46
-
-
65949124446
-
Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men
-
et al.
-
Kindblom, J.M., Ohlsson, C., Ljunggren, O., et al. (2009) Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men. Journal of Bone and Mineral Research, 24, 785-791.
-
(2009)
Journal of Bone and Mineral Research
, vol.24
, pp. 785-791
-
-
Kindblom, J.M.1
Ohlsson, C.2
Ljunggren, O.3
-
47
-
-
77955398568
-
Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels
-
et al.
-
Yeap, B.B., Chubb, S.A., Flicker, L., et al. (2010) Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels. European Journal of Endocrinology, 163, 265-272.
-
(2010)
European Journal of Endocrinology
, vol.163
, pp. 265-272
-
-
Yeap, B.B.1
Chubb, S.A.2
Flicker, L.3
-
48
-
-
77953921007
-
Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome
-
Saleem, U., Mosley Jr, T.H., &, Kullo, I.J., (2010) Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology, 30, 1474-1478.
-
(2010)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.30
, pp. 1474-1478
-
-
Saleem, U.1
Mosley, Jr.T.H.2
Kullo, I.J.3
-
49
-
-
50049111403
-
Relationship between osteocalcin and glucose metabolism in postmenopausal women
-
et al.
-
Im, J.A., Yu, B.P., Jeon, J.Y., et al. (2008) Relationship between osteocalcin and glucose metabolism in postmenopausal women. Clinica Chimica Acta, 396, 66-69.
-
(2008)
Clinica Chimica Acta
, vol.396
, pp. 66-69
-
-
Im, J.A.1
Yu, B.P.2
Jeon, J.Y.3
-
50
-
-
62349099001
-
Association between serum osteocalcin and markers of metabolic phenotype
-
et al.
-
Pittas, A.G., Harris, S.S., Eliades, M., et al. (2009) Association between serum osteocalcin and markers of metabolic phenotype. Journal of Clinical Endocrinology and Metabolism, 94, 827-832.
-
(2009)
Journal of Clinical Endocrinology and Metabolism
, vol.94
, pp. 827-832
-
-
Pittas, A.G.1
Harris, S.S.2
Eliades, M.3
-
51
-
-
70449727666
-
Serum osteocalcin concentrations in relation to glucose and lipid metabolism in Chinese individuals
-
et al.
-
Zhou, M., Ma, X., Li, H., et al. (2009) Serum osteocalcin concentrations in relation to glucose and lipid metabolism in Chinese individuals. European Journal of Endocrinology, 161, 723-729.
-
(2009)
European Journal of Endocrinology
, vol.161
, pp. 723-729
-
-
Zhou, M.1
Ma, X.2
Li, H.3
-
52
-
-
84857367794
-
Associations of total osteocalcin with all-cause and cardiovascular mortality in older men. The health in men study
-
et al., Feb 26 [Epub ahead of publication].
-
Yeap, B.B., Chubb, S.A., Flicker, L., et al. (2011) Associations of total osteocalcin with all-cause and cardiovascular mortality in older men. The health in men study. Osteoporosis International, Feb 26 [Epub ahead of publication].
-
(2011)
Osteoporosis International
-
-
Yeap, B.B.1
Chubb, S.A.2
Flicker, L.3
-
53
-
-
58149377704
-
Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus
-
et al.
-
Kanazawa, I., Yamaguchi, T., Yamamoto, M., et al. (2009) Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 94, 45-49.
-
(2009)
Journal of Clinical Endocrinology and Metabolism
, vol.94
, pp. 45-49
-
-
Kanazawa, I.1
Yamaguchi, T.2
Yamamoto, M.3
-
54
-
-
78651518046
-
Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus
-
et al.
-
Kanazawa, I., Yamaguchi, T., Yamauchi, M., et al. (2010) Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus. Osteoporosis International, 22, 187-194.
-
(2010)
Osteoporosis International
, vol.22
, pp. 187-194
-
-
Kanazawa, I.1
Yamaguchi, T.2
Yamauchi, M.3
-
55
-
-
47249094150
-
Phylloquinone intake, insulin sensitivity, and glycemic status in men and women
-
Yoshida, M., Booth, S.L., Meigs, J.B., et al. (2008) Phylloquinone intake, insulin sensitivity, and glycemic status in men and women. American Journal of Clinical Nutrition, 88, 210-215. (Pubitemid 351988701)
-
(2008)
American Journal of Clinical Nutrition
, vol.88
, Issue.1
, pp. 210-215
-
-
Yoshida, M.1
Booth, S.L.2
Meigs, J.B.3
Saltzman, E.4
Jacques, P.F.5
-
56
-
-
73349104406
-
The uncarboxylated form of osteocalcin is associated with improved glucose tolerance and enhanced beta-cell function in middle-aged male subjects
-
et al.
-
Hwang, Y.C., Jeong, I.K., Ahn, K.J., et al. (2009) The uncarboxylated form of osteocalcin is associated with improved glucose tolerance and enhanced beta-cell function in middle-aged male subjects. Diabetes Metabolism Research and Reviews, 25, 768-772.
-
(2009)
Diabetes Metabolism Research and Reviews
, vol.25
, pp. 768-772
-
-
Hwang, Y.C.1
Jeong, I.K.2
Ahn, K.J.3
-
57
-
-
70350650807
-
Gamma-carboxylation of osteocalcin and insulin resistance in older men and women
-
et al.
-
Shea, M.K., Gundberg, C.M., Meigs, J.B., et al. (2009) Gamma-carboxylation of osteocalcin and insulin resistance in older men and women. American Journal of Clinical Nutrition, 90, 1230-1235.
-
(2009)
American Journal of Clinical Nutrition
, vol.90
, pp. 1230-1235
-
-
Shea, M.K.1
Gundberg, C.M.2
Meigs, J.B.3
-
58
-
-
77956737410
-
Bone and glucose metabolism: A two-way street
-
Motyl, K.J., McCabe, L.R., &, Schwartz, A.V., (2010) Bone and glucose metabolism: a two-way street. Archives of Biochemistry and Biophysics, 503, 2-10.
-
(2010)
Archives of Biochemistry and Biophysics
, vol.503
, pp. 2-10
-
-
Motyl, K.J.1
McCabe, L.R.2
Schwartz, A.V.3
-
59
-
-
39849098616
-
Determinants and correlates of serum undercarboxylated osteocalcin
-
DOI 10.1159/000114211
-
Nimptsch, K., Hailer, S., Rohrmann, S., et al. (2007) Determinants and correlates of serum undercarboxylated osteocalcin. Annals of Nutrition and Metabolism, 51, 563-570. (Pubitemid 351315923)
-
(2007)
Annals of Nutrition and Metabolism
, vol.51
, Issue.6
, pp. 563-570
-
-
Nimptsch, K.1
Hailer, S.2
Rohrmann, S.3
Gedrich, K.4
Wolfram, G.5
Linseisen, J.6
-
60
-
-
78049257829
-
PPARgamma: A circadian transcription factor in adipogenesis and osteogenesis
-
Kawai, M., &, Rosen, C.J., (2010) PPARgamma: a circadian transcription factor in adipogenesis and osteogenesis. Nature Reviews. Endocrinology, 6, 629-636.
-
(2010)
Nature Reviews. Endocrinology
, vol.6
, pp. 629-636
-
-
Kawai, M.1
Rosen, C.J.2
-
61
-
-
0033933211
-
Osteopenia in insulin-dependent diabetes mellitus: Prevalence and aspects of pathophysiology
-
Kemink, S.A., Hermus, A.R., Swinkels, L.M., et al. (2000) Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. Journal of Endocrinological Investigation, 23, 295-303. (Pubitemid 30426548)
-
(2000)
Journal of Endocrinological Investigation
, vol.23
, Issue.5
, pp. 295-303
-
-
Kemink, S.A.G.1
Hermus, A.R.M.M.2
Swinkels, L.M.J.W.3
Lutterman, J.A.4
Smals, A.G.H.5
-
62
-
-
33746419250
-
Prospective study of diabetes and risk of hip fracture: The nurses' health study
-
DOI 10.2337/dc06-0440
-
Janghorbani, M., Feskanich, D., Willett, W.C., et al. (2006) Prospective study of diabetes and risk of hip fracture: the Nurses' Health Study. Diabetes Care, 29, 1573-1578. (Pubitemid 44127583)
-
(2006)
Diabetes Care
, vol.29
, Issue.7
, pp. 1573-1578
-
-
Janghorbani, M.1
Feskanich, D.2
Willett, W.C.3
Hu, F.4
-
63
-
-
77953401724
-
Bone mass and strength in older men with type 2 diabetes: The Osteoporotic Fractures in Men Study
-
et al.
-
Petit, M.A., Paudel, M.L., Taylor, B.C., et al. (2010) Bone mass and strength in older men with type 2 diabetes: the Osteoporotic Fractures in Men Study. Journal of Bone and Mineral Research, 25, 285-291.
-
(2010)
Journal of Bone and Mineral Research
, vol.25
, pp. 285-291
-
-
Petit, M.A.1
Paudel, M.L.2
Taylor, B.C.3
-
65
-
-
33845405222
-
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
DOI 10.1056/NEJMoa066224
-
Kahn, S.E., Haffner, S.M., Heise, M.A., et al. (2006) Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. New England Journal of Medicine, 355, 2427-2443. (Pubitemid 44903747)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.23
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
Herman, W.H.4
Holman, R.R.5
Jones, N.P.6
Kravitz, B.G.7
Lachin, J.M.8
O'Neill, M.C.9
Zinman, B.10
Viberti, G.11
-
66
-
-
58849094131
-
Long-term use of thiazolidinediones and fractures in type 2 diabetes: A meta-analysis
-
Loke, Y.K., Singh, S., &, Furberg, C.D., (2009) Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis. CMAJ, 180, 32-39.
-
(2009)
CMAJ
, vol.180
, pp. 32-39
-
-
Loke, Y.K.1
Singh, S.2
Furberg, C.D.3
-
67
-
-
76149114236
-
Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus
-
et al.
-
Habib, Z.A., Havstad, S.L., Wells, K., et al. (2010) Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 95, 592-600.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, pp. 592-600
-
-
Habib, Z.A.1
Havstad, S.L.2
Wells, K.3
-
68
-
-
33847006604
-
Review: Peroxisome proliferator-activated receptor gamma and adipose tissue - Understanding obesity-related changes in regulation of lipid and glucose metabolism
-
Sharma, A.M., &, Staels, B., (2007) Review: peroxisome proliferator-activated receptor gamma and adipose tissue - understanding obesity-related changes in regulation of lipid and glucose metabolism. Journal of Clinical Endocrinology and Metabolism, 92, 386-395.
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, pp. 386-395
-
-
Sharma, A.M.1
Staels, B.2
-
69
-
-
0033197899
-
Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPAR2
-
DOI 10.1002/(SICI)1097-4644(19 990901)74:3<357::AID-JCB5>3.0.CO;2-7
-
Lecka-Czernik, B., Gubrij, I., Moerman, E.J., et al. (1999) Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2. Journal of Cellular Biochemistry, 74, 357-371. (Pubitemid 29344887)
-
(1999)
Journal of Cellular Biochemistry
, vol.74
, Issue.3
, pp. 357-371
-
-
Lecka-Czernik, B.1
Gubrij, I.2
Moerman, E.J.3
Kajkenova, O.4
Lipschitz, D.A.5
Manolagas, S.C.6
Jilka, R.L.7
-
70
-
-
61449123058
-
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells
-
et al.
-
Shockley, K.R., Lazarenko, O.P., Czernik, P.J., et al. (2009) PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells. Journal of Cellular Biochemistry, 106, 232-246.
-
(2009)
Journal of Cellular Biochemistry
, vol.106
, pp. 232-246
-
-
Shockley, K.R.1
Lazarenko, O.P.2
Czernik, P.J.3
-
71
-
-
0033212964
-
PPAR mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
DOI 10.1016/S1097-2765(00)80210-5
-
Kubota, N., Terauchi, Y., Miki, H., et al. (1999) PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Molecular Cell, 4, 597-609. (Pubitemid 29531139)
-
(1999)
Molecular Cell
, vol.4
, Issue.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
Satoh, S.7
Nakano, R.8
Ishii, C.9
Sugiyama, T.10
Kazuhiro, E.11
Tsubamoto, Y.12
Okuno, A.13
Murakami, K.14
Sekihara, H.15
Hasegawa, G.16
Naito, M.17
Toyoshima, Y.18
Tanaka, S.19
Shiota, K.20
Kitamura, T.21
Fujita, T.22
Ezaki, O.23
Aizawa, S.24
Nagai, R.25
Tobe, K.26
Kimura, S.27
Kadowaki, T.28
more..
-
72
-
-
2142652189
-
PPAR insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
-
DOI 10.1172/JCI200419900
-
Akune, T., Ohba, S., Kamekura, S., et al. (2004) PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. Journal of Clinical Investigation, 113, 846-855. (Pubitemid 38544143)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.6
, pp. 846-855
-
-
Akune, T.1
Ohba, S.2
Kamekura, S.3
Yamaguchi, M.4
Chung, U.-I.5
Kubota, N.6
Terauchi, Y.7
Harada, Y.8
Azuma, Y.9
Nakamura, K.10
Kadowaki, T.11
Kawaguchi, H.12
-
73
-
-
34147154970
-
The peroxisome proliferator-activated receptor- agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: A randomized, controlled trial
-
DOI 10.1210/jc.2006-2646
-
Grey, A., Bolland, M., Gamble, G., et al. (2007) The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial. Journal of Clinical Endocrinology and Metabolism, 92, 1305-1310. (Pubitemid 46556402)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.4
, pp. 1305-1310
-
-
Grey, A.1
Bolland, M.2
Gamble, G.3
Wattie, D.4
Horne, A.5
Davidson, J.6
Reid, I.R.7
-
74
-
-
33846412672
-
Activation of peroxisome proliferator-activated receptor (PPAR) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo
-
DOI 10.1210/en.2006-1121
-
Lecka-Czernik, B., Ackert-Bicknell, C., Adamo, M.L., et al. (2007) Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo. Endocrinology, 148, 903-911. (Pubitemid 46143190)
-
(2007)
Endocrinology
, vol.148
, Issue.2
, pp. 903-911
-
-
Lecka-Czernik, B.1
Ackert-Bicknell, C.2
Adamo, M.L.3
Marmolejos, V.4
Churchill, G.A.5
Shockley, K.R.6
Reid, I.R.7
Grey, A.8
Rosen, C.J.9
-
75
-
-
33748079106
-
Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways
-
DOI 10.1002/jcb.20890
-
Shinoda, Y., Yamaguchi, M., Ogata, N., et al. (2006) Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. Journal of Cellular Biochemistry, 99, 196-208. (Pubitemid 44297964)
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, Issue.1
, pp. 196-208
-
-
Shinoda, Y.1
Yamaguchi, M.2
Ogata, N.3
Akune, T.4
Kubota, N.5
Yamauchi, T.6
Terauchi, Y.7
Kadowaki, T.8
Takeuchi, Y.9
Fukumoto, S.10
Ikeda, T.11
Hoshi, K.12
Chung, U.-I.13
Nakamura, K.14
Kawaguchi, H.15
-
76
-
-
67651148206
-
In vitro and in vivo effects of adiponectin on bone
-
et al.
-
Williams, G.A., Wang, Y., Callon, K.E., et al. (2009) In vitro and in vivo effects of adiponectin on bone. Endocrinology, 150, 3603-3610.
-
(2009)
Endocrinology
, vol.150
, pp. 3603-3610
-
-
Williams, G.A.1
Wang, Y.2
Callon, K.E.3
-
77
-
-
0036963450
-
Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis
-
DOI 10.1210/jc.87.3.985
-
Johnell, O., Scheele, W.H., Lu, Y., et al. (2002) Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis. Journal of Clinical Endocrinology and Metabolism 87, 985-992. (Pubitemid 36121052)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.3
, pp. 985-992
-
-
Johnell, O.1
Scheele, W.H.2
Lu, Y.3
Reginster, J.-Y.4
Need, A.G.5
Seeman, E.6
-
78
-
-
67649227047
-
Bone as an endocrine organ
-
Fukumoto, S., &, Martin, T.J., (2009) Bone as an endocrine organ. Trends in Endocrinology and Metabolism, 20, 230-236.
-
(2009)
Trends in Endocrinology and Metabolism
, vol.20
, pp. 230-236
-
-
Fukumoto, S.1
Martin, T.J.2
-
79
-
-
79952289069
-
Endocrine regulation of male fertility by the skeleton
-
et al.
-
Oury, F., Sumara, G., Sumara, O., et al. (2010) Endocrine regulation of male fertility by the skeleton. Cell, 144, 796-809.
-
(2010)
Cell
, vol.144
, pp. 796-809
-
-
Oury, F.1
Sumara, G.2
Sumara, O.3
|