Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 1, 2009, Pages 45-49

  Kanazawa, Ippei ^a   Yamaguchi, Toru ^a   Yamamoto, Masahiro ^a   Yamauchi, Mika ^a   Kurioka, Soichi ^a   Yano, Shozo ^a   Sugimoto, Toshitsugu ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALKALINE PHOSPHATASE BONE ISOENZYME; C PEPTIDE; CREATININE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OSTEOCALCIN;

ADULT; AGE; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CARDIOVASCULAR PARAMETERS; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PULSE WAVE; SYSTOLIC BLOOD PRESSURE;

ANIMALIA;

EID: 58149377704     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-1455     Document Type: Article

References (28)

1. McFarlane SI, Muniyappa R, Shin JJ, Bathtiyar G, Sowers JR 2004 Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link? Endocrine 23:1-10
2. Browner WS, Pressman AR, Nevitt MC, Cauley JA, Cummings SR 1993 Association between low bone density and stroke in elderly women. Stroke 24:940-946
3. Tanko LB, Christiansen C, Cox DA, Geiger MJ, McNabb MA, Cummings SR 2005 Relationship between osteoporosis and cardiovascular disease in postmenopausal women. J Bone Miner Res 20:1912-1920
4. Vogt MT, San Valentin R, Forrest KY, Nevitt MC, Cauley JA 1997 Bone mineral density and aortic calcification: the Study of Osteoporotic Fractures. J Am Geriatr Soc 45:140-145
5. von der Recke P, Hansen MA, Hassager C 1999 The association between low bone mass at the menopause and cardiovascular mortality. Am J Med 106:273-278
6. O'Brien KD, Kuusisto J, Reichenbach DD, Ferguson M, Giachelli C, Alpers CE, Otto CM 1995 Osteopontin is expressed in human aortic valvular lesions. Circulation 92:2163-2168
7. Shanahan CM, Cary NR, Metcalfe JC, Weissberg PL 1994 High expression of genes for calcification-regulating protein in human atherosclerotic plaques. J Clin Invest 93:2393-2402
8. Bini A, Mann KG, Kudryk BJ, Schoen FJ 1999 Noncollagenous bone matrix proteins, calcification, and thrombosis in carotid artery atherosclerosis. Arterioscler Thromb Vasc Biol 19:1852-1861
9. Hauschka PV, Lian JB, Cole DE, Gundberg CM 1989 Osteocalcin and matrix protein: vitamin K-dependent proteins in bone. Physiol Rev 69:990-1047
10. Price PA 1989 Gla-containing proteins of bone. Connect Tissue Res 21:51-57
11. Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G 2007 Endocrine regulation of energy metabolism by the skeleton. Cell 130:456-469
12. Ferron M, Hinoi E, Karsenty G, Ducy P 2008 Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci USA 105:5266-5270
13. Kaji H, Tobimatsu T, Naito J, Iu MF, Yamauchi M, Sugimoto T, Chihara K 2006 Body composition and vertebral fracture risk in female patients treated with glucocorticoid. Osteoporos Int 17:627-633
14. Sugimoto T, Nishiyama K, Kuribayashi F, Chihara K 1997 Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures. J Bone Miner Res 12:1272-1279
15. Kaji H, Nomura R, Yamauchi M, Chihara K, Sugimoto T 2006 The usefulness of bone metabolic indices for the prediction of changes in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism. Horm Metab Res 38:411-416
16. Friedewald WT, Levy RI, Fredrickson DS 1972 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502
17. Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T Serum DHEA-S level is associated with the presence of atherosclerosis in postmenopausal women with type 2 diabetes mellitus. Endocr J 55:667-675
18. Andoh N, Minami J, Ishimitsu T, Ohrui M, Matsuoka H 2006 Relationship between markers of inflammation and brachial-ankle pulse wave velocity in Japanese men. Int Heart J 47:409-420
19. Verhaeghe J, Suiker AM, Nyomba BL, Visser WJ, Einhorn TA, Dequeker J, Bouillon R 1989 Bone mineral homeostasis in spontaneously diabetic BB rats. II. Impaired bone turnover and decreased osteocalcin synthesis. Endocrinology 124:573-582
20. Gerdhem P, Isaksson A, Akesson K, Obrant KJ 2005 Increased bone density and decreased bone turnover, but no evident alteration of fracture susceptibility in elderly women with diabetes mellitus. Osteoporos Int 16:1506-1512
21. Okazaki R, Totsuka Y, Hamano K, Ajima M, Miura M, Hirota Y, Hata K, Fukumoto S, Matsumoto T 1997 Metabolic improvement of poorly controlled noninsulin-dependent diabetes mellitus decreases bone turnover. J Clin Endocrinol Metab 82:2915-2920
22. Botolin S, McCabe LR 2006 Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways. J Cell Biochem 99:411-424
23. Pennisi P, Signorelli SS, Riccobene S, Celotta G, Di Pino L, La Malfa T, Fiore CE 2004 Low bone density and abnormal bone turnover in patients with atherosclerosis of peripheral vessels. Osteoporos Int 15:389-395
24. Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL 1994 TGF-β 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 93:2106-2113
25. Dhore CR, Cleutjens JP, Lutgens E, Cleutjens KB, Geusens PP, Kitslaar PJ, Tordoir JH, Spronk HM, Vermeer C, Daemen MJ 2001 Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 21:1998-2003
26. Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenthy G 1997 Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 386:78-81
27. Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE 2004 Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 279:12152-12162
28. Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, Hara K, Hada Y, Vasseur F, Froguel P, Kimura S, Nagai R, Kadowaki T 2003 Impaired multimerization of human adiponectin mutants associated with diabetes: molecular structure and multimer formation of adiponectin. J Biol Chem 278:40352-40363