Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 2, 2011, Pages 390-401

  Bushman, Lane R ^a   Kiser, Jennifer J ^a   Rower, Joseph E ^a   Klein, Brandon ^a   Zheng, Jia Hua ^a   Ray, Michelle L ^a   Anderson, Peter L ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Analytical methods; Clinical pharmacology; Intracellular pharmacology; LC MS MS; Nucleoside analogs

Indexed keywords

EMTRICITABINE; LAMIVUDINE; NUCLEOSIDE ANALOG; TENOFOVIR; ZIDOVUDINE;

ANION EXCHANGE; ARTICLE; DEPHOSPHORYLATION; ENZYME ASSAY; EXTRACELLULAR MATRIX; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

ADENINE; ANION EXCHANGE RESINS; ANTIVIRAL AGENTS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DEOXYCYTIDINE; DIPHOSPHATES; HUMANS; LAMIVUDINE; LEUKOCYTES, MONONUCLEAR; NUCLEOSIDES; PHOSPHATES; PHOSPHONIC ACIDS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ZIDOVUDINE;

EID: 79960043515     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.05.039     Document Type: Article

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