On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 29, 2009, Pages 3659-3666

  Kuklenyik, Zsuzsanna ^a   Martin, Amy ^b   Pau, Chou Pong ^b   Holder, Angela ^b   Youngpairoj, Ae S ^b   Zheng, Qi ^b   Cong, Mian Er ^b   Garcia Lerma, J Gerardo ^b   Heneine, Walid ^b   Pirkle, James L ^a   Barr, John R ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Anion exchange; Ion pair; Liquid chromatography; Mass spectrometry; Metabolism; Metabolites; On line analysis; quadrupole

Indexed keywords

ANION EXCHANGE; ION PAIR LIQUID CHROMATOGRAPHY; ION-PAIR; ON-LINE ANALYSIS; QUADRUPOLES;

AMINES; BIOCHEMISTRY; BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; DYNAMIC POSITIONING; EXTRACTION; INTERNET PROTOCOLS; ION EXCHANGE; IONS; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; PERCOLATION (SOLID STATE); PLASMAS; THERMAL CONDUCTIVITY;

LIQUID CHROMATOGRAPHY;

CARBON 13; DRUG METABOLITE; EMTRICITABINE; EMTRICITABINE TRIPHOSPHATE; LAMIVUDINE; LAMIVUDINE TRIPHOSPHATE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR DIPHOSPHATE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANION EXCHANGE; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; DRUG HALF LIFE; DRUG METABOLISM; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERMETHOD COMPARISON; ION PAIR CHROMATOGRAPHY; ISOTOPE LABELING; MACACA; MASS SPECTROMETRY; NONHUMAN; ONLINE ANALYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY;

ADENINE; CHROMATOGRAPHY, ION EXCHANGE; DEOXYCYTIDINE; HUMANS; LAMIVUDINE; LEUKOCYTES, MONONUCLEAR; MASS SPECTROMETRY; PHOSPHONIC ACIDS; POLYPHOSPHATES; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 72049125123     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.09.007     Document Type: Article

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