Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases

Epigenomics

Volumn 3, Issue 3, 2011, Pages 279-294

  Low, Felicia M ^a   Gluckman, Peter D ^a,b   Hanson, Mark A ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b AGENCY FOR SCIENCE   (Singapore)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

developmental origins of health and disease; developmental plasticity; epigenetics; evolutionary medicine; fitness; metabolic and cardiovascular disease; mismatch

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; DNA METHYLTRANSFERASE 1; GLUCOCORTICOID RECEPTOR; HISTONE DEACETYLASE 1; HISTONE H3; MICRORNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SOMATOMEDIN B; TRANSCRIPTION FACTOR PDX 1;

AMINO TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DEVELOPMENTAL STAGE; DISEASE PREDISPOSITION; DNA METHYLATION; EMBRYO DEVELOPMENT; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EPIGENETICS; FAMILY HISTORY; GENE LOCUS; GENE SILENCING; GENETIC RISK; GENETIC SUSCEPTIBILITY; HETEROCHROMATIN; HISTONE MODIFICATION; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTENSION; INHERITANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAUTERINE GROWTH RETARDATION; LIPID METABOLISM; MARASMUS; MATERNAL NUTRITION; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OVERNUTRITION; OXIDATIVE PHOSPHORYLATION; PHENOTYPIC PLASTICITY; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; RETROPOSON; REVIEW; RISK ASSESSMENT; SEDENTARY LIFESTYLE; UPREGULATION;

ANIMALS; BIOLOGICAL EVOLUTION; CARDIOVASCULAR DISEASES; EPIGENESIS, GENETIC; FEMALE; FETAL DEVELOPMENT; HUMANS; METABOLIC DISEASES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS;

ANIMALIA;

EID: 79960029052     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.11.17     Document Type: Review

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