Osthol ameliorates fat milk-induced fatty liver in mice by regulation of hepatic sterol regulatory element-binding protein-1c/2-mediated target gene expression

European Journal of Pharmacology

Volumn 666, Issue 1-3, 2011, Pages 183-188

  Du, Rao ^a,b   Xue, Jie ^b   Wang, Heng Bin ^c   Zhang, Yan ^d   Xie, Mei Lin ^b  

^a CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^c Changshu Leiyunshang Pharmaceutical Co Ltd   (China)

^d The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University   (China)

Author keywords

Cnidium monnieri (L.) Cusson; Hyperlipidemic fatty liver; Osthol; Sterol regulatory element binding protein 1c; Sterol regulatory element binding protein 2

Indexed keywords

CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; FATTY ACID; FATTY ACID SYNTHASE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; MILK FAT; OSTHOLE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID BLOOD LEVEL; FATTY LIVER; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HYPERLIPIDEMIA; LIPID LIVER LEVEL; LIPID STORAGE; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; COUMARINS; DIETARY FATS; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; GENE EXPRESSION REGULATION; LIVER; MALE; MICE; MILK; ORGAN SIZE; RECEPTORS, LDL; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEINS; TRIGLYCERIDES;

EID: 79960016926     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.05.014     Document Type: Article

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