메뉴 건너뛰기




Volumn 13, Issue 7, 2011, Pages 827-837

A direct role for Met endocytosis in tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; ACTIN; CBL PROTEIN; CLATHRIN; DYNAMIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; RAC1 PROTEIN; SCATTER FACTOR RECEPTOR;

EID: 79959999334     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2257     Document Type: Article
Times cited : (205)

References (57)
  • 1
    • 0036899420 scopus 로고    scopus 로고
    • Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
    • DOI 10.1016/S1534-5807(02)00364-7
    • Teis, D., Wunderlich, W. & Huber, L. A. Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Dev. Cell 3, 803-814 (2002). (Pubitemid 35460781)
    • (2002) Developmental Cell , vol.3 , Issue.6 , pp. 803-814
    • Teis, D.1    Wunderlich, W.2    Huber, L.A.3
  • 3
    • 42949092018 scopus 로고    scopus 로고
    • The endosomal protein appl1 mediates Akt substrate specificity and cell survival in vertebrate development
    • DOI 10.1016/j.cell.2008.02.044, PII S0092867408003942
    • Schenck, A. et al. The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell 133, 486-497 (2008). (Pubitemid 351608689)
    • (2008) Cell , vol.133 , Issue.3 , pp. 486-497
    • Schenck, A.1    Goto-Silva, L.2    Collinet, C.3    Rhinn, M.4    Giner, A.5    Habermann, B.6    Brand, M.7    Zerial, M.8
  • 4
    • 0034976247 scopus 로고    scopus 로고
    • Signaling on the endocytic pathway
    • DOI 10.1034/j.1600-0854.2001.002006375.x
    • McPherson, P. S., Kay, B. K. & Hussain, N. K. Signaling on the endocytic pathway. Traffic 2, 375-384 (2001). (Pubitemid 32574004)
    • (2001) Traffic , vol.2 , Issue.6 , pp. 375-384
    • McPherson, P.S.1    Kay, B.K.2    Hussain, N.K.3
  • 5
    • 6344248651 scopus 로고    scopus 로고
    • PKC controls HGF-dependent c-Met traffic, signalling and cell migration
    • DOI 10.1038/sj.emboj.7600396
    • Kermorgant, S., Zicha, D. & Parker, P. J. PKC controls HGF-dependent c-Met Traffic, signalling and cell migration. EMBO J. 23, 3721-3734 (2004). (Pubitemid 39389704)
    • (2004) EMBO Journal , vol.23 , Issue.19 , pp. 3721-3734
    • Kermorgant, S.1    Zicha, D.2    Parker, P.J.3
  • 6
    • 3142592401 scopus 로고    scopus 로고
    • Not just a sink: Endosomes in control of signal transduction
    • DOI 10.1016/j.ceb.2004.06.005, PII S0955067404000742
    • Miaczynska, M., Pelkmans, L. & Zerial, M. Not just a sink: endosomes in control of signal transduction. Curr. Opin. Cell Biol. 16, 400-406 (2004). (Pubitemid 38903146)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.4 , pp. 400-406
    • Miaczynska, M.1    Pelkmans, L.2    Zerial, M.3
  • 7
    • 51649130231 scopus 로고    scopus 로고
    • Receptor trafficking controls weak signal delivery: A strategy used by c-Met for STAT3 nuclear accumulation
    • Kermorgant, S. & Parker, P. J. Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J. Cell Biol. 182, 855-863 (2008).
    • (2008) J. Cell Biol , vol.182 , pp. 855-863
    • Kermorgant, S.1    Parker, P.J.2
  • 8
    • 0034597554 scopus 로고    scopus 로고
    • Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy
    • Sorkin, A., McClure, M., Huang, F. & Carter, R. Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Curr. Biol. 10, 1395-1398 (2000).
    • (2000) Curr. Biol , vol.10 , pp. 1395-1398
    • Sorkin, A.1    McClure, M.2    Huang, F.3    Carter, R.4
  • 9
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • DOI 10.1126/science.274.5295.2086
    • Vieira, A. V., Lamaze, C. & Schmid, S. L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089 (1996). (Pubitemid 27020702)
    • (1996) Science , vol.274 , Issue.5295 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 10
    • 0035819073 scopus 로고    scopus 로고
    • NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
    • DOI 10.1016/S0896-6273(01)00526-8
    • Howe, C. L., Valletta, J. S., Rusnak, A. S. & Mobley, W. C. NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron 32, 801-814 (2001). (Pubitemid 34024842)
    • (2001) Neuron , vol.32 , Issue.5 , pp. 801-814
    • Howe, C.L.1    Valletta, J.S.2    Rusnak, A.S.3    Mobley, W.C.4
  • 11
    • 22944447140 scopus 로고    scopus 로고
    • Signaling and endocytosis: A team effort for cell migration
    • DOI 10.1016/j.devcel.2005.07.007, PII S1534580705002601
    • Le Roy, C. & Wrana, J. L. Signaling and endocytosis: a team effort for cell migration. Dev. Cell 9, 167-168 (2005). (Pubitemid 41051734)
    • (2005) Developmental Cell , vol.9 , Issue.2 , pp. 167-168
    • Le Roy, C.1    Wrana, J.L.2
  • 12
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • DOI 10.1016/j.cell.2006.02.025, PII S009286740600242X
    • Polo, S. & Di Fiore, P. P. Endocytosis conducts the cell signaling orchestra. Cell 124, 897-900 (2006). (Pubitemid 43344231)
    • (2006) Cell , vol.124 , Issue.5 , pp. 897-900
    • Polo, S.1    Di Fiore, P.P.2
  • 13
    • 34548092634 scopus 로고    scopus 로고
    • Signaling on the endocytic pathway
    • DOI 10.1016/j.ceb.2007.04.021, PII S0955067407000932
    • von Zastrow, M. & Sorkin, A. Signaling on the endocytic pathway. Curr. Opin. Cell Biol. 19, 436-445 (2007). (Pubitemid 47287673)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.4 , pp. 436-445
    • Von Zastrow, M.1    Sorkin, A.2
  • 14
    • 25444461165 scopus 로고    scopus 로고
    • J. c-Met signalling: Spatio-temporal decisions
    • Kermorgant, S. & Parker, P. J. c-Met signalling: spatio-temporal decisions. Cell Cycle 4, 352-355 (2005).
    • (2005) Cell Cycle , vol.4 , pp. 352-355
    • Kermorgant, S.1    Parker, P.2
  • 15
    • 62849097694 scopus 로고    scopus 로고
    • New roles for endosomes: From vesicular carriers to multi-purpose platforms
    • Gould, G. W. & Lippincott-Schwartz, J. New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nat. Rev. Mol. Cell Biol. 10, 287-292 (2009).
    • (2009) Nat. Rev. Mol. Cell Biol , vol.10 , pp. 287-292
    • Gould, G.W.1    Lippincott-Schwartz, J.2
  • 16
    • 22944455544 scopus 로고    scopus 로고
    • Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration
    • DOI 10.1016/j.devcel.2005.06.004, PII S1534580705002169
    • Jekely, G., Sung, H. H., Luque, C. M. & Rorth, P. Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration. Dev. Cell 9, 197-207 (2005). (Pubitemid 41051739)
    • (2005) Developmental Cell , vol.9 , Issue.2 , pp. 197-207
    • Jekely, G.1    Sung, H.-H.2    Luque, C.M.3    Rorth, P.4
  • 17
    • 0036787904 scopus 로고    scopus 로고
    • Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
    • Wang, Y., Pennock, S., Chen, X. & Wang, Z. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol. Cell Biol. 22, 7279-7290 (2002).
    • (2002) Mol. Cell Biol , vol.22 , pp. 7279-7290
    • Wang, Y.1    Pennock, S.2    Chen, X.3    Wang, Z.4
  • 18
    • 33644524741 scopus 로고    scopus 로고
    • Cell-signalling dynamics in time and space
    • Kholodenko, B. N. Cell-signalling dynamics in time and space. Nat. Rev. Mol. Cell Biol. 7, 165-176 (2006).
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 165-176
    • Kholodenko, B.N.1
  • 19
    • 56149094041 scopus 로고    scopus 로고
    • Endocytosis and cancer: An ̀insider' network with dangerous liaisons
    • Lanzetti, L. & Di Fiore, P. P. Endocytosis and cancer: an ̀insider' network with dangerous liaisons. Traffic 9, 2011-2021 (2008).
    • (2008) Traffic , vol.9 , pp. 2011-2021
    • Lanzetti, L.1    Di Fiore, P.P.2
  • 20
    • 54549102284 scopus 로고    scopus 로고
    • Derailed endocytosis: An emerging feature of cancer
    • Mosesson, Y., Mills, G. B. & Yarden, Y. Derailed endocytosis: an emerging feature of cancer. Nat. Rev. Cancer 8, 835-850 (2008).
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 835-850
    • Mosesson, Y.1    Mills, G.B.2    Yarden, Y.3
  • 22
    • 0034939549 scopus 로고    scopus 로고
    • Pathway specificity for Met signalling
    • DOI 10.1038/35083116
    • Comoglio, P. M. Pathway specificity for Met signalling. Nat. Cell Biol. 3, E161-E162 (2001). (Pubitemid 32624413)
    • (2001) Nature Cell Biology , vol.3 , Issue.7
    • Comoglio, P.M.1
  • 24
    • 19544389146 scopus 로고    scopus 로고
    • C-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
    • DOI 10.1016/j.canlet.2004.09.044, PII S0304383504007657
    • Christensen, J. G., Burrows, J. & Salgia, R. c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention. Cancer Lett. 225, 1-26 (2005). (Pubitemid 40732764)
    • (2005) Cancer Letters , vol.225 , Issue.1 , pp. 1-26
    • Christensen, J.G.1    Burrows, J.2    Salgia, R.3
  • 28
    • 25144439353 scopus 로고    scopus 로고
    • A mouse model of activating met mutations
    • Graveel, C. R., London, C. A. & Vande Woude, G. F. A mouse model of activating met mutations. Cell Cycle 4, 518-520 (2005). (Pubitemid 41359769)
    • (2005) Cell Cycle , vol.4 , Issue.4 , pp. 518-520
    • Graveel, C.R.1    London, C.A.2    Vande Woude, G.F.3
  • 29
    • 33748756029 scopus 로고    scopus 로고
    • VEGF regulates the mobilisation of VEGFR-2/KDR from an intracellular endothelial storage compartment
    • Gampel, A. et al. VEGF regulates the mobilisation of VEGFR-2/KDR from an intracellular endothelial storage compartment. Blood 108, 2624-2631 (2006).
    • (2006) Blood , vol.108 , pp. 2624-2631
    • Gampel, A.1
  • 30
    • 0043208954 scopus 로고    scopus 로고
    • Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met
    • DOI 10.1074/jbc.M302116200
    • Kermorgant, S., Zicha, D. & Parker, P. J. Protein kinase C controls microtubule-based Traffic but not proteasomal degradation of c-Met. J. Biol. Chem. 278, 28921-28929 (2003). (Pubitemid 36935802)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.31 , pp. 28921-28929
    • Kermorgant, S.1    Zicha, D.2    Parker, P.J.3
  • 31
    • 45549100234 scopus 로고    scopus 로고
    • Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis
    • Kirchhausen, T., Macia, E. & Pelish, H. E. Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis. Methods Enzymol. 438, 77-93 (2008).
    • (2008) Methods Enzymol , vol.438 , pp. 77-93
    • Kirchhausen, T.1    MacIa, E.2    Pelish, H.E.3
  • 32
    • 67549119243 scopus 로고    scopus 로고
    • Inhibition of dynamin mediated endocytosis by the dynoles synthesis and functional activity of a family of indoles
    • Hill, T. A. et al. Inhibition of dynamin mediated endocytosis by the dynoles synthesis and functional activity of a family of indoles. J. Med. Chem. 52, 3762-3773 (2009).
    • (2009) J. Med. Chem , vol.52 , pp. 3762-3773
    • Hill, T.A.1
  • 33
    • 34447126344 scopus 로고    scopus 로고
    • Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase
    • DOI 10.1074/jbc.M610835200
    • Li, N., Lorinczi, M., Ireton, K. & Elferink, L. A. Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase. J. Biol. Chem. 282, 16764-16775 (2007). (Pubitemid 47093241)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.23 , pp. 16764-16775
    • Li, N.1    Lorinczi, M.2    Ireton, K.3    Elferink, L.A.4
  • 34
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: Intertwining molecular networks
    • Sorkin, A. & von Zastrow, M. Endocytosis and signalling: intertwining molecular networks. Nat. Rev. Mol. Cell Biol. 10, 609-622 (2009).
    • (2009) Nat. Rev. Mol. Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    Von Zastrow, M.2
  • 36
    • 0034660080 scopus 로고    scopus 로고
    • Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src
    • Nakaigawa, N., Weirich, G., Schmidt, L. & Zbar, B. Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src. Oncogene 19, 2996-3002 (2000). (Pubitemid 30389090)
    • (2000) Oncogene , vol.19 , Issue.26 , pp. 2996-3002
    • Nakaigawa, N.1    Weirich, G.2    Schmidt, L.3    Zbar, B.4
  • 37
    • 0029999150 scopus 로고    scopus 로고
    • Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility
    • Ponzetto, C. et al. Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility. J. Biol. Chem. 271, 14119-14123 (1996).
    • (1996) J. Biol. Chem , vol.271 , pp. 14119-14123
    • Ponzetto, C.1
  • 38
    • 0027910431 scopus 로고
    • Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
    • Egan, S. E. et al. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 45-51 (1993). (Pubitemid 23144959)
    • (1993) Nature , vol.362 , Issue.6424 , pp. 45-51
    • Egan, S.E.1    Giddings, B.W.2    Brooks, M.W.3    Buday, L.4    Sizeland, A.M.5    Weinberg, R.A.6
  • 39
    • 50149083752 scopus 로고    scopus 로고
    • Mammalian Rho GTPases: New insights into their functions from in vivo studies
    • Heasman, S. J. & Ridley, A. J. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol. 9, 690-701 (2008).
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , pp. 690-701
    • Heasman, S.J.1    Ridley, A.J.2
  • 41
    • 33845751024 scopus 로고    scopus 로고
    • Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signaling
    • DOI 10.1128/MCB.01153-06
    • Xiang, Z., Kreisel, F., Cain, J., Colson, A. & Tomasson, M. H. Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signalling. Mol. Cell Biol. 27, 267-282 (2007). (Pubitemid 46013250)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.1 , pp. 267-282
    • Xiang, Z.1    Kreisel, F.2    Cain, J.3    Colson, A.4    Tomasson, M.H.5
  • 42
    • 36448958570 scopus 로고    scopus 로고
    • RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface
    • DOI 10.1038/sj.onc.1210591, PII 1210591
    • Runeberg-Roos, P., Virtanen, H. & Saarma, M. RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface. Oncogene 26, 7909-7915 (2007). (Pubitemid 350261786)
    • (2007) Oncogene , vol.26 , Issue.57 , pp. 7909-7915
    • Runeberg-Roos, P.1    Virtanen, H.2    Saarma, M.3
  • 43
    • 5644241730 scopus 로고    scopus 로고
    • The kinase activity of-broblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling
    • Lievens, P. M., Mutinelli, C., Baynes, D. & Liboi, E. The kinase activity of-broblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling. J. Biol. Chem. 279, 43254-43260 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 43254-43260
    • Lievens, P.M.1    Mutinelli, C.2    Baynes, D.3    Liboi, E.4
  • 44
    • 70350013557 scopus 로고    scopus 로고
    • Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes
    • Choudhary, C. et al. Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol. Cell 36, 326-339 (2009).
    • (2009) Mol. Cell , vol.36 , pp. 326-339
    • Choudhary, C.1
  • 45
    • 65349190643 scopus 로고    scopus 로고
    • Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality
    • Schmidt-Arras, D. et al. Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality. Blood 113, 3568-3576 (2009).
    • (2009) Blood , vol.113 , pp. 3568-3576
    • Schmidt-Arras, D.1
  • 46
    • 75749096347 scopus 로고    scopus 로고
    • The endocytic matrix
    • Scita, G. & Di Fiore, P. P. The endocytic matrix. Nature 463, 464-473.
    • Nature , vol.463 , pp. 464-473
    • Scita, G.1    Di Fiore, P.P.2
  • 47
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller, P. A. et al. Mutant p53 drives invasion by promoting integrin recycling. Cell 139, 1327-1341 (2009).
    • (2009) Cell , vol.139 , pp. 1327-1341
    • Muller, P.A.1
  • 49
    • 0035930341 scopus 로고    scopus 로고
    • Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
    • DOI 10.1016/S1097-2765(01)00378-1
    • Peschard, P. et al. Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Mol. Cell 8, 995-1004 (2001). (Pubitemid 34031802)
    • (2001) Molecular Cell , vol.8 , Issue.5 , pp. 995-1004
    • Peschard, P.1    Fournier, T.M.2    Lamorte, L.3    Naujokas, M.A.4    Band, H.5    Langdon, W.Y.6    Park, M.7
  • 50
    • 0025370578 scopus 로고
    • Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells
    • DOI 10.1083/jcb.110.5.1541
    • Honegger, A. M., Schmidt, A., Ullrich, A. & Schlessinger, J. Separate endocytic pathways of kinase-defective and-active EGF receptor mutants expressed in same cells. J. Cell Biol. 110, 1541-1548 (1990). (Pubitemid 20169490)
    • (1990) Journal of Cell Biology , vol.110 , Issue.5 , pp. 1541-1548
    • Honegger, A.M.1    Schmidt, A.2    Ullrich, A.3    Schlessinger, J.4
  • 52
    • 27344439995 scopus 로고    scopus 로고
    • Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation
    • DOI 10.1038/sj.embor.7400491, PII 7400491
    • Wang, Q., Villeneuve, G. & Wang, Z. Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation. EMBO Rep. 6, 942-948 (2005). (Pubitemid 41521949)
    • (2005) EMBO Reports , vol.6 , Issue.10 , pp. 942-948
    • Wang, Q.1    Villeneuve, G.2    Wang, Z.3
  • 53
    • 33750339742 scopus 로고    scopus 로고
    • Integrin traffic
    • DOI 10.1242/jcs.03216
    • Pellinen, T. & Ivaska, J. Integrin Traffic. J. Cell Sci. 119, 3723-3731 (2006). (Pubitemid 44614425)
    • (2006) Journal of Cell Science , vol.119 , Issue.18 , pp. 3723-3731
    • Pellinen, T.1    Ivaska, J.2
  • 54
    • 78651105303 scopus 로고    scopus 로고
    • Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration
    • Assaker, G., Ramel, D., Wculek, S. K., Gonzalez-Gaitan, M. & Emery, G. Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. Proc. Natl Acad. Sci. USA 107, 22558-22563 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 22558-22563
    • Assaker, G.1    Ramel, D.2    Wculek, S.K.3    Gonzalez-Gaitan, M.4    Emery, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.