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Volumn 39, Issue 2, 2011, Pages 345-352

Overexpression of EGR-1 modulates the activity of NF-κB and AP-1 in prostate carcinoma PC-3 and LNCaP cell lines

Author keywords

AP 1; Early growth response gene; NF B; Nuclear factors; Prostate carcinoma; Soft agar assay

Indexed keywords

CISPLATIN; I KAPPA B; LUCIFERASE; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR EGR 1;

EID: 79959952702     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1047     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 23044497683 scopus 로고    scopus 로고
    • Maximum tumor diameter is an independent predictor of prostate-specific antigen recurrence in prostate cancer
    • Eichelberger L, O Koch M, Eble J, Ulbright T, Juliar B and Cheng L: Maximum tumor diameter is an independent predictor of prostate-specific antigen recurrence in prostate cancer Mod Pathol 18: 886-890, 2005.
    • (2005) Mod Pathol , vol.18 , pp. 886-890
    • Eichelberger, L.1    O Koch, M.2    Eble, J.3    Ulbright, T.4    Juliar, B.5    Cheng, L.6
  • 2
    • 0037809237 scopus 로고    scopus 로고
    • Egr1 promotes growth and survival of prostate cancer cells: Identification of novel Egr1 target genes
    • DOI 10.1074/jbc.M210279200
    • Virolle T, Krones-Herzig A, Baron V, Gregorio GG, Adamson ED and Mercola D: Egr1 promotes growth and survival of prostate cancer cells: identification of novel Egr1 target genes. Int J Biol Chem 278: 11802-11810, 2003. (Pubitemid 36800149)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 11802-11810
    • Virolle, T.1    Krones-Herzig, A.2    Baron, V.3    De Gregorio, G.4    Adamson, E.D.5    Mercola, D.6
  • 5
    • 0042068270 scopus 로고    scopus 로고
    • The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells
    • DOI 10.1042/BJ20021918
    • Pignatelli M, Luna-Medina R, Perez-Rendon A, Santos A and Perez-Castillo A: The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells. Int Biochem J 373: 739-746, 2003. (Pubitemid 36981083)
    • (2003) Biochemical Journal , vol.373 , Issue.3 , pp. 739-746
    • Pignatelli, M.1    Luna-Medina, R.2    Perez-Rendon, A.3    Santos, A.4    Perez-Castillo, A.5
  • 8
    • 0036328973 scopus 로고    scopus 로고
    • Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells
    • DOI 10.1091/mbc.01-12-0572
    • Amorino G, Hamilton V, Valerie K, Dent P, Lammering G and Schmidt-Ullrich R: Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells. Int Mol Biol Cell 13: 2233-2244, 2002. (Pubitemid 34831329)
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.7 , pp. 2233-2244
    • Amorino, G.P.1    Hamilton, V.M.2    Valerie, K.3    Dent, P.4    Lammering, G.5    Schmidt-Ullrich, R.K.6
  • 9
    • 0036270508 scopus 로고    scopus 로고
    • Egr1 transcription factor: Multiple roles in prostate tumor cell growth and survival
    • DOI 10.1159/000059711
    • Adamson ED and Mercola D: Egr1 transcription factor, multiple roles in prostate tumor cell growth and survival. Tumour Biol 23: 93-102, 2002. (Pubitemid 34639111)
    • (2002) Tumor Biology , vol.23 , Issue.2 , pp. 93-102
    • Adamson, E.D.1    Mercola, D.2
  • 10
    • 12344254223 scopus 로고    scopus 로고
    • Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts
    • DOI 10.1152/japplphysiol.00821.2004
    • Banks MF, Gerasimovskaya EV, Tucker D, Frid MG, Carpenter TC and Stenmark KR: Egr-1 antisense oligonucleotide inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblast. Int J Appl Physiol 98: 732-738, 2004. (Pubitemid 40129989)
    • (2005) Journal of Applied Physiology , vol.98 , Issue.2 , pp. 732-738
    • Banks, M.F.1    Gerasimovskaya, E.V.2    Tucker, D.A.3    Frid, M.G.4    Carpenter, T.C.5    Stenmark, K.R.6
  • 11
    • 0030046508 scopus 로고    scopus 로고
    • Life death, and the pursuit of apoptosis
    • White E: Life death, and the pursuit of apoptosis. Genes Dev 10: 1-15, 1996.
    • (1996) Genes Dev , vol.10 , pp. 1-15
    • White, E.1
  • 13
    • 0031602586 scopus 로고    scopus 로고
    • Suppression of growth and transformation and induction of apoptosis by EGR-1
    • Liu C, Rangnekar VM, Adamson E and Mercola D: Suppression of growth and transformation and induction of apoptosis by EGR-1. Cancer Gene Ther 5: 3-28, 1998. (Pubitemid 128639987)
    • (1998) Cancer Gene Therapy , vol.5 , Issue.1 , pp. 3-28
    • Liu, C.1    Rangnekar, V.M.2    Adamson, E.3    Mercola, D.4
  • 14
    • 0041464740 scopus 로고    scopus 로고
    • Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth
    • DOI 10.1038/nm905
    • Fahmy R, Dass C, Sun L, Chesterman C and Khachigian L: Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth. Nat Med 9: 1026-1032, 2003. (Pubitemid 37021782)
    • (2003) Nature Medicine , vol.9 , Issue.8 , pp. 1026-1032
    • Fahmy, R.G.1    Dass, C.R.2    Sun, L.-Q.3    Chesterman, C.N.4    Khachigian, L.M.5
  • 16
    • 0035997978 scopus 로고    scopus 로고
    • Curcumin Suppresses Activation of NF-kappaB and AP-1 Induced by Phorbol Ester in Cultured Human Promyelocytic Leukemia Cells
    • Han S, Keum Y-S, Seo H-J and Surh Y-J: Curcumin suppresses activation of NF-κB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells. Biochem Mol Biol 35: 337-342, 2002. (Pubitemid 34655880)
    • (2002) Journal of Biochemistry and Molecular Biology , vol.35 , Issue.3 , pp. 337-342
    • Han, S.-S.1    Keum, Y.-S.2    Seo, H.-J.3    Surh, Y.-J.4
  • 17
    • 4243687105 scopus 로고    scopus 로고
    • The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: The JB6 model is predictive
    • Dhar A, Young MR and Colburn NH: The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol Cell Biochem 234-235: 185-193, 2002.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 185-193
    • Dhar, A.1    Young, M.R.2    Colburn, N.H.3
  • 18
    • 0036738640 scopus 로고    scopus 로고
    • AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model
    • Suzukawa K, Weber TJ and Colburn NH: AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ Health Perspect 110: 865-870, 2002.
    • (2002) Environ Health Perspect , vol.110 , pp. 865-870
    • Suzukawa, K.1    Weber, T.J.2    Colburn, N.H.3
  • 19
    • 0023814640 scopus 로고
    • Epidermal growth factor stimulates transcription of the c-Jun protoncogene in rat fibroblasts
    • Quantin B and Breathnach R: Epidermal growth factor stimulates transcription of the c-Jun protoncogene in rat fibroblasts. Nature 334: 538-539, 1988.
    • (1988) Nature , vol.334 , pp. 538-539
    • Quantin, B.1    Breathnach, R.2
  • 21
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M: The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 22
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle PA and Henkel T: Function and activation of NF-κB in the immune system. Annu Rev Immunol 12: 141-179, 1994.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 24
    • 0030791042 scopus 로고    scopus 로고
    • Transcription factors as activators of gene transcription: AP-1 and NF-kappa B
    • Adcock IM: Transcription factors as activators of gene transcription: AP-1 and NF-kappa B. Monaldi Arch Chest Dis 52: 178-186, 1997.
    • (1997) Monaldi Arch Chest Dis , vol.52 , pp. 178-186
    • Adcock, I.M.1
  • 25
    • 0033655159 scopus 로고    scopus 로고
    • Assaying NF-κB and AP-1 DNA-binding and transcriptional activity
    • Mueller J and Pahl H: Assaying NF-κB and AP-1 DNA-binding and transcriptional activity. Methods Mol Biol 99: 205-216, 2000.
    • (2000) Methods Mol Biol , vol.99 , pp. 205-216
    • Mueller, J.1    Pahl, H.2
  • 26
    • 0028841622 scopus 로고
    • The genomic response of tumor cells to hypoxia and reoxygenation: Differential activation of transcription factors AP-1 and NF-κB
    • Rupec RA and Baeuerle PA: The genomic response of tumor cells to hypoxia and reoxygenation: differential activation of transcription factors AP-1 and NF-κB. Eur J Biochem 234: 632-640, 1995.
    • (1995) Eur J Biochem , vol.234 , pp. 632-640
    • Rupec, R.A.1    Baeuerle, P.A.2
  • 27
    • 77949474627 scopus 로고    scopus 로고
    • The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines
    • Parra E and Ferreira J: The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines. Oncol Rep 22: 1159-1165, 2010.
    • (2010) Oncol Rep , vol.22 , pp. 1159-1165
    • Parra, E.1    Ferreira, J.2
  • 28
    • 78149296302 scopus 로고    scopus 로고
    • Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell lines growth
    • Parra E and Ferreira J: Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell lines growth. Oncol Rep 24: 1339-1345, 2010.
    • (2010) Oncol Rep , vol.24 , pp. 1339-1345
    • Parra, E.1    Ferreira, J.2
  • 29
    • 70449363841 scopus 로고    scopus 로고
    • Downregulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3
    • Parra E, Ortega A and Saenz L: Downregulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3. Oncol Rep 22: 1513-1518, 2009.
    • (2009) Oncol Rep , vol.22 , pp. 1513-1518
    • Parra, E.1    Ortega, A.2    Saenz, L.3
  • 30
    • 27544444555 scopus 로고    scopus 로고
    • Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity
    • Inostroza J Saenz L, Calaf G, Cabello G and Parra E: Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity. Biol Res 38: 163-178, 2005. (Pubitemid 41535617)
    • (2005) Biological Research , vol.38 , Issue.2-3 , pp. 163-178
    • Inostroza, J.1    Saenz, L.2    Calaf, G.3    Cabello, G.4    Parra, E.5
  • 31
    • 0032103002 scopus 로고    scopus 로고
    • Overexpression of p65 and c-Jun substitutes for B7-1 costimulation by targeting the CD28RE within the IL-2 promoter
    • Parra E, McGuire K, Hedlund G and Dohlsten M: Overexpression of p65 and c-Jun substitutes for B7-1 costimulation by targeting the CD28RE within the IL-2 promoter. J Immunol 160: 5374-5381, 1998. (Pubitemid 28267826)
    • (1998) Journal of Immunology , vol.160 , Issue.11 , pp. 5374-5381
    • Parra, E.1    McGuire, K.2    Hedlund, G.3    Dohlsten, M.4
  • 32
    • 0031018905 scopus 로고    scopus 로고
    • Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT binding
    • Parra E, Varga M, Hedlund G, Kalland T and Dohlsten M: Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT binding. Mol Cell Biol 17: 1314, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 1314
    • Parra, E.1    Varga, M.2    Hedlund, G.3    Kalland, T.4    Dohlsten, M.5
  • 34
    • 0034725671 scopus 로고    scopus 로고
    • 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced c-Jun N-terminal kinase (JNK) phosphatase renders immortalized or transformed epithelial cells refractory to TPA-inducible JNK activity
    • DOI 10.1074/jbc.M909273199
    • Zhou H, Lin A, Gu Z, Chen S, Park N and Chiu R: 12-O-tetrade- canoylphorbol-13-acetate (TPA)-induced c-Jun N-terminal kinase (JNK) phosphatase renders immortalized or transformed epithelial cells refractory to TPA-inducible JNK activity. J Biol Chem 275: 22868-22875, 2000. (Pubitemid 30646172)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.30 , pp. 22868-22875
    • Zhou, H.1    Lin, A.2    Gu, Z.3    Chen, S.4    Park, N.-H.5    Chiu, R.6
  • 35
    • 25144434873 scopus 로고    scopus 로고
    • Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1
    • DOI 10.1158/1078-0432.CCR-05-0450
    • Mohanty S, Huang J and Basu A: Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1. Clin Cancer Res 11: 6730-6737, 2005. (Pubitemid 41339016)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6730-6737
    • Mohanty, S.1    Huang, J.2    Basu, A.3
  • 36
    • 41649114838 scopus 로고    scopus 로고
    • Functions of bifans in context of multiple regulatory motifs in signaling networks
    • Lipshtat A, Purushothaman S, Iyengar R and Maayan A: Functions of bifans in context of multiple regulatory motifs in signaling networks. Biophys J 94: 2566-2579, 2008.
    • (2008) Biophys J , vol.94 , pp. 2566-2579
    • Lipshtat, A.1    Purushothaman, S.2    Iyengar, R.3    Maayan, A.4
  • 37
    • 0036679169 scopus 로고    scopus 로고
    • Cell stress and MEKK1-mediated c-Jun activation modulate NF-κB activity and cell viability
    • Sánchez I, Aznar S, Martínez M, Lacal J and Perona R: Cell stress and MEKK1-mediated c-Jun activation modulate NF-κB activity and cell viability. Mol Biol Cell 13: 2933-2945, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 2933-2945
    • Sánchez, I.1    Aznar, S.2    Martínez, M.3    Lacal, J.4    Perona, R.5
  • 38
    • 0025720735 scopus 로고
    • The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation
    • Angel P and Karin M: The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation. Biochem Biophys Acta 1072: 129-157, 1991.
    • (1991) Biochem Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 39
    • 0027173483 scopus 로고
    • JunB differs from c-Jun in its DNA-binding and dimerization domains, and respresses c-Jun by formation of inactive heterodimers
    • Deng T and Karin M: JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev 7: 479-490, 1993. (Pubitemid 23139240)
    • (1993) Genes and Development , vol.7 , Issue.3 , pp. 479-490
    • Deng, T.1    Karin, M.2
  • 40
    • 0035971406 scopus 로고    scopus 로고
    • AP-1-introductory remarks
    • Wagner EF: AP-1-introductory remarks. Oncogene 20: 2334-2335, 2001.
    • (2001) Oncogene , vol.20 , pp. 2334-2335
    • Wagner, E.F.1
  • 42
    • 1242339629 scopus 로고    scopus 로고
    • The c-Jun Dimerization Protein 2 Inhibits Cell Transformation and Acts as a Tumor Suppressor Gene
    • DOI 10.1074/jbc.M307608200
    • Heinrich R, Livne E, Ben-Izhak O and Aronheim A: The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene. J Biol Chem 279: 5708-5715, 2004. (Pubitemid 38220600)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5708-5715
    • Heinrich, R.1    Livne, E.2    Ben-Izhak, O.3    Aronheim, A.4
  • 43
    • 0029009884 scopus 로고
    • Induction of c-fos, jun B and egr-1 expression by haloperidol in PC12 cells: Involvement of calcium
    • Esteve L, Haby C, Rodeau J, Humblot N, Aunis D and Zwiller J: Induction of c-fos, jun B and egr-1 expression by haloperidol in PC12 cells: involvement of calcium. Neuropharmacology 34: 439-448, 1995.
    • (1995) Neuropharmacology , vol.34 , pp. 439-448
    • Esteve, L.1    Haby, C.2    Rodeau, J.3    Humblot, N.4    Aunis, D.5    Zwiller, J.6
  • 44
    • 0033515523 scopus 로고    scopus 로고
    • Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells
    • Morawietz H, Ma YH, Vives F, Wilson E, Sukhatme V, Holtz J and Ives H: Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells. Circulation Res 84: 678-687, 1999. (Pubitemid 29157335)
    • (1999) Circulation Research , vol.84 , Issue.6 , pp. 678-687
    • Morawietz, H.1    Ma, Y.-H.2    Vives, F.3    Wilson, E.4    Sukhatme, V.P.5    Holtz, J.6    Ives, H.E.7
  • 45
    • 0032483017 scopus 로고    scopus 로고
    • JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?
    • Karin M and Delhase M: JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action? Proc Natl Acad Sci USA 95: 9067-9079, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9067-9079
    • Karin, M.1    Delhase, M.2
  • 46
    • 51849144630 scopus 로고    scopus 로고
    • Signal transduction pathways involving p38 MAPK, JNK, NFκB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1β and dynamic compression
    • Chowdhury T, Salter DM, Bader DL and Lee DA: Signal transduction pathways involving p38 MAPK, JNK, NFκB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1β and dynamic compression. Inflamm Res 57: 306-313, 2008.
    • (2008) Inflamm Res , vol.57 , pp. 306-313
    • Chowdhury, T.1    Salter, D.M.2    Bader, D.L.3    Lee, D.A.4
  • 47
    • 41449118699 scopus 로고    scopus 로고
    • The Transcription Factor EGR1 Controls Both the Proliferation and Localization of Hematopoietic Stem Cells
    • DOI 10.1016/j.stem.2008.01.015, PII S1934590908000568
    • Min IM, Pietramaggiori G, Kim F, Passegué F, Stevenson K and Wagers A: The transcription factor EGR1 controls both the proliferation and localization of hematopoietic. Cell Stem Cell 4: 380-391, 2008. (Pubitemid 351455239)
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 380-391
    • Min, I.M.1    Pietramaggiori, G.2    Kim, F.S.3    Passegue, E.4    Stevenson, K.E.5    Wagers, A.J.6
  • 48
    • 0027209950 scopus 로고
    • Differential induction of Egr-1 expression in WEHI-231 sublines does not correlate with apoptosis
    • Gottschalk A, Joseph L and Quintáns J: Differential induction of Egr-1 expression in WEHI-231 sublines does not correlate with apoptosis. Eur J Immunol 23: 2011-2015, 1993.
    • (1993) Eur J Immunol , vol.23 , pp. 2011-2015
    • Gottschalk, A.1    Joseph, L.2    Quintáns, J.3
  • 49
    • 79551660279 scopus 로고    scopus 로고
    • Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism
    • Boone D, Qi Y, Li Z and Hann S: Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism. Proc Natl Acad Sci USA 108: 2 632-637, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.2 , pp. 632-637
    • Boone, D.1    Qi, Y.2    Li, Z.3    Hann, S.4
  • 50
    • 77954256636 scopus 로고    scopus 로고
    • 1,2,3 Inhibition of cell proliferation by CD44: Akt is inactivated and EGR-1 is down-regulated
    • Zhang LS, Ma HW, Greyner HJ Zuo W and Mummert M: 1,2,3 inhibition of cell proliferation by CD44: Akt is inactivated and EGR-1 is down-regulated. Cell Prolif 43: 385-395, 2010.
    • (2010) Cell Prolif , vol.43 , pp. 385-395
    • Zhang, L.S.1    Ma, H.W.2    Greyner, H.J.3    Zuo, W.4    Mummert, M.5


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