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Volumn 23, Issue 4, 2010, Pages 1159-1165

The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines

Author keywords

Breast carcinoma; Camptothecin; Early growth response gene; Short RNA interference

Indexed keywords

CAMPTOTHECIN; EARLY GROWTH RESPONSE FACTOR 1; SMALL INTERFERING RNA;

EID: 77949474627     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000746     Document Type: Article
Times cited : (23)

References (47)
  • 2
    • 27844492326 scopus 로고    scopus 로고
    • Combinatorial pharmacogenetics
    • Wilke RA, Reif DM and Moore JH: Combinatorial pharmacogenetics. Nature 4: 911-918, 2005.
    • (2005) Nature , vol.4 , pp. 911-918
    • Wilke, R.A.1    Reif, D.M.2    Moore, J.H.3
  • 3
    • 14844341251 scopus 로고    scopus 로고
    • Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila
    • Agrawal N, Pallos J, Slepko N, et al: Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila. Proc Natl Acad Sci USA 102: 3777-3781, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3777-3781
    • Agrawal, N.1    Pallos, J.2    Slepko, N.3
  • 4
    • 0025317094 scopus 로고
    • Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signal
    • Cao X, Koski RA, Gashler A, et al: Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signal. Mol Cell Biol 10: 1931-1939, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 1931-1939
    • Cao, X.1    Koski, R.A.2    Gashler, A.3
  • 5
    • 0024281381 scopus 로고
    • A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization
    • Sukhatme VP, Cao X, Chang LC, et al: A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53: 37-43, 1988.
    • (1988) Cell , vol.53 , pp. 37-43
    • Sukhatme, V.P.1    Cao, X.2    Chang, L.C.3
  • 6
    • 0026587842 scopus 로고
    • The Egr transcription factor family: From signal transduction to kidney differentiation
    • Sukhatme VP: The Egr transcription factor family: from signal transduction to kidney differentiation. Kidney Int 4: 550-553, 1992.
    • (1992) Kidney Int , vol.4 , pp. 550-553
    • Sukhatme, V.P.1
  • 7
    • 0037809237 scopus 로고    scopus 로고
    • Egr1 promotes growth and survival of prostate cancer cells: Identification of novel Egr1 target genes
    • Virolle T, Krones-Herzig A, Baron V, Gregorio GG, Adamson ED and Mercola D: Egr1 promotes growth and survival of prostate cancer cells: identification of novel Egr1 target genes. Int J Biol Chem 278: 11802-11810, 2003.
    • (2003) Int J Biol Chem , vol.278 , pp. 11802-11810
    • Virolle, T.1    Krones-Herzig, A.2    Baron, V.3    Gregorio, G.G.4    Adamson, E.D.5    Mercola, D.6
  • 9
    • 0034628411 scopus 로고    scopus 로고
    • EGR-1 enhances tumor growth and modulates the effect of the Wilms' tumor 1 gene products on tumorigenicity
    • Scharnhorst V, Menke AL and Attema J: EGR-1 enhances tumor growth and modulates the effect of the Wilms' tumor 1 gene products on tumorigenicity. Oncogene 19: 791-800, 2000.
    • (2000) Oncogene , vol.19 , pp. 791-800
    • Scharnhorst, V.1    Menke, A.L.2    Attema, J.3
  • 10
    • 0042068270 scopus 로고    scopus 로고
    • The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells
    • Pignatelli M, Luna R, Perez A, Santos A and Castillo AP: The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells. Biochem J 373: 739-746, 2003.
    • (2003) Biochem J , vol.373 , pp. 739-746
    • Pignatelli, M.1    Luna, R.2    Perez, A.3    Santos, A.4    Castillo, A.P.5
  • 11
    • 0034810154 scopus 로고    scopus 로고
    • The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and agiogenesis
    • Houston P, Campbell CJ, Svaren J, Milbrandt J and Braddock M: The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and agiogenesis. Biochem Biophys Res Commun 283: 480-486, 2001.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 480-486
    • Houston, P.1    Campbell, C.J.2    Svaren, J.3    Milbrandt, J.4    Braddock, M.5
  • 13
    • 0036328973 scopus 로고    scopus 로고
    • Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells
    • Amorino G, Hamilton V, Valerie K, Dent P, Lammering G and Schmidt-Ullrich RK: Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells. Mol Biol Cell 13: 2233-2244, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 2233-2244
    • Amorino, G.1    Hamilton, V.2    Valerie, K.3    Dent, P.4    Lammering, G.5    Schmidt-Ullrich, R.K.6
  • 14
    • 23044497683 scopus 로고    scopus 로고
    • Maximum tumor diameter is an independent predictor of prostate-specific antigen recurrence in prostate cancer
    • Eichelberger L, Koch M, Eble J, Ulbright T, Juliar B and Cheng L: Maximum tumor diameter is an independent predictor of prostate-specific antigen recurrence in prostate cancer. Mod Pathol 18: 886-890, 2005.
    • (2005) Mod Pathol , vol.18 , pp. 886-890
    • Eichelberger, L.1    Koch, M.2    Eble, J.3    Ulbright, T.4    Juliar, B.5    Cheng, L.6
  • 15
    • 0030055094 scopus 로고    scopus 로고
    • Current perspectives on camptothecins in cancer treatment
    • Dancey J and Eisenhauer EA: Current perspectives on camptothecins in cancer treatment. Br J Cancer 74: 327-338, 1996.
    • (1996) Br J Cancer , vol.74 , pp. 327-338
    • Dancey, J.1    Eisenhauer, E.A.2
  • 16
    • 67649997027 scopus 로고    scopus 로고
    • CKD-602, a camptothecin derivative, inhibits proliferation and induces apoptosis in glioma cell lines
    • Kim YY, Park CK, Kim SK, et al: CKD-602, a camptothecin derivative, inhibits proliferation and induces apoptosis in glioma cell lines. Oncol Rep 21: 1413-1419, 2009.
    • (2009) Oncol Rep , vol.21 , pp. 1413-1419
    • Kim, Y.Y.1    Park, C.K.2    Kim, S.K.3
  • 17
    • 61449224487 scopus 로고    scopus 로고
    • A novel camptothecin derivative incorporated in nano-carrier induced distinguished improvement in solubility, stability and anti-tumor activity both in vitro and in vivo
    • Han M, He CX, Fang QL, et al: A novel camptothecin derivative incorporated in nano-carrier induced distinguished improvement in solubility, stability and anti-tumor activity both in vitro and in vivo. Pharm Res 26: 926-935, 2008.
    • (2008) Pharm Res , vol.26 , pp. 926-935
    • Han, M.1    He, C.X.2    Fang, Q.L.3
  • 19
    • 0344958632 scopus 로고    scopus 로고
    • Water-insoluble camptothecin analogues as potential antiviral drugs
    • Pantazis P, Han Z, Chatterjee D and Wyche J: Water-insoluble camptothecin analogues as potential antiviral drugs. J Biomed Sci 6: 1-7, 1999.
    • (1999) J Biomed Sci , vol.6 , pp. 1-7
    • Pantazis, P.1    Han, Z.2    Chatterjee, D.3    Wyche, J.4
  • 20
    • 0028818337 scopus 로고
    • Growth inhibition of human cancer metastases by camptothecins in newly developed xenograft models
    • Potmesil M, Vardeman D, Kozielski A, Mendoza J, Stehlin JS and Giovanella BC: Growth inhibition of human cancer metastases by camptothecins in newly developed xenograft models. Cancer Res 55: 5637-5641, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5637-5641
    • Potmesil, M.1    Vardeman, D.2    Kozielski, A.3    Mendoza, J.4    Stehlin, J.S.5    Giovanella, B.C.6
  • 21
    • 0024358188 scopus 로고
    • DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
    • Giovanella BC, Stehlin JS, Wall ME, et al: DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 2446: 1046-1048, 1989.
    • (1989) Science , vol.2446 , pp. 1046-1048
    • Giovanella, B.C.1    Stehlin, J.S.2    Wall, M.E.3
  • 22
    • 0025912553 scopus 로고
    • Complete growth inhibition ofhuman cancer xenografts in nude mice by treatment with 2O-(S)-camptothecin
    • Giovanella BC, Hinz H, Kozielski AJ, Stehlin JS, Silber R and Potmesil M: Complete growth inhibition ofhuman cancer xenografts in nude mice by treatment with 2O-(S)-camptothecin. Cancer Res 51: 3052-3055, 1991.
    • (1991) Cancer Res , vol.51 , pp. 3052-3055
    • Giovanella, B.C.1    Hinz, H.2    Kozielski, A.J.3    Stehlin, J.S.4    Silber, R.5    Potmesil, M.6
  • 23
    • 0005227608 scopus 로고    scopus 로고
    • Small interfering RNAs a revolutionary tool for the analysis of gene function and gene therapy
    • Tuschl T and Borkhardt A: Small interfering RNAs a revolutionary tool for the analysis of gene function and gene therapy. Mol Interv 2: 158-167, 2002.
    • (2002) Mol Interv , vol.2 , pp. 158-167
    • Tuschl, T.1    Borkhardt, A.2
  • 24
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery M, Kostas S, Driver S and Mello C: 'Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans'. Nature 391: 806-811, 1998.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.3    Kostas, S.4    Driver, S.5    Mello, C.6
  • 25
    • 34547134721 scopus 로고    scopus 로고
    • Suppression of immunostimulatory siRNA-driven innate immune activation by 2′-modified RNAs
    • Sioud M, Furset G and Cekaite L: Suppression of immunostimulatory siRNA-driven innate immune activation by 2′-modified RNAs. Biochem Biophys Res Commun 361: 122-126, 2007.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 122-126
    • Sioud, M.1    Furset, G.2    Cekaite, L.3
  • 26
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W and Tuschl T: RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15: 188-200, 2001.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 27
    • 42649103333 scopus 로고    scopus 로고
    • Does the understanding of immune activation by RNA predict the design of safe siRNA?
    • Sioud M: Does the understanding of immune activation by RNA predict the design of safe siRNA? Front Biosci 13: 4379-4392, 2008.
    • (2008) Front Biosci , vol.13 , pp. 4379-4392
    • Sioud, M.1
  • 28
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ and Rossi JJ: Unlocking the potential of the human genome with RNA interference. Nature 431: 371-378, 2004.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 29
    • 6044248871 scopus 로고    scopus 로고
    • Therapeutic potential of RNA interference
    • Stevenson M: Therapeutic potential of RNA interference. N Engl J Med 351: 1772-1777, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1772-1777
    • Stevenson, M.1
  • 30
    • 70449363841 scopus 로고    scopus 로고
    • Downregulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3
    • Parra E, Ortega A and Saenz L: Downregulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3. Oncol Rep 22: 1513-1518, 2009.
    • (2009) Oncol Rep , vol.22 , pp. 1513-1518
    • Parra, E.1    Ortega, A.2    Saenz, L.3
  • 31
    • 0347623204 scopus 로고    scopus 로고
    • Non-specific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNA)
    • Persengiev SP, Zhu X and Green MR: Non-specific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNA). RNA 10: 12-18, 2004.
    • (2004) RNA , vol.10 , pp. 12-18
    • Persengiev, S.P.1    Zhu, X.2    Green, M.R.3
  • 32
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector based RNAi technology to suppress gene expression in mammalian cells
    • Sui G, Soohoo C, Affar E, Gay F, Forrester WC and Shi Y: A DNA vector based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 99: 5515-5520, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5515-5520
    • Sui, G.1    Soohoo, C.2    Affar, E.3    Gay, F.4    Forrester, W.C.5    Shi, Y.6
  • 33
    • 27544444555 scopus 로고    scopus 로고
    • Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity
    • Inostroza J, Saenz L, Calaf G, Cabello G and Parra E: Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity. Biol Res 38: 163-178, 2005.
    • (2005) Biol Res , vol.38 , pp. 163-178
    • Inostroza, J.1    Saenz, L.2    Calaf, G.3    Cabello, G.4    Parra, E.5
  • 34
    • 0030837544 scopus 로고    scopus 로고
    • Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation
    • Huang RP, Fan Y, de Belle I, Niemeyer C, Gottardis MM, Mercola D and Adamson ED: Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation. Int J Cancer 72: 102-109, 1997.
    • (1997) Int J Cancer , vol.72 , pp. 102-109
    • Huang, R.P.1    Fan, Y.2    de Belle, I.3    Niemeyer, C.4    Gottardis, M.M.5    Mercola, D.6    Adamson, E.D.7
  • 35
    • 77949462421 scopus 로고    scopus 로고
    • Cancer treatment using viruses and camptothecins
    • Carbonero G and Supko JG: Cancer treatment using viruses and camptothecins. Clin Cancer Res 8: 641-661, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 641-661
    • Carbonero, G.1    Supko, J.G.2
  • 36
    • 0038167666 scopus 로고    scopus 로고
    • The camptothecins
    • Pizzolato JF and Saltz LB: The camptothecins. Lancet 361: 2235-2242, 2003.
    • (2003) Lancet , vol.361 , pp. 2235-2242
    • Pizzolato, J.F.1    Saltz, L.B.2
  • 37
    • 0031846891 scopus 로고
    • Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2
    • Ruo-Pan Huang RP, Fan Y, Peng A, Zeng ZL, Reed JC and Adamson ED: Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2. Int J Cancer 77: 880-886, 1995.
    • (1995) Int J Cancer , vol.77 , pp. 880-886
    • Ruo-Pan Huang, R.P.1    Fan, Y.2    Peng, A.3    Zeng, Z.L.4    Reed, J.C.5    Adamson, E.D.6
  • 39
    • 2942604975 scopus 로고    scopus 로고
    • Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma
    • Calogero A, Lombari V, Porcellini A, et al: Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma. Cancer Cell Int 4: 1-8, 2004.
    • (2004) Cancer Cell Int , vol.4 , pp. 1-8
    • Calogero, A.1    Lombari, V.2    Porcellini, A.3
  • 40
    • 0036232664 scopus 로고    scopus 로고
    • Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines
    • Hao MW, Liang YR, Liu YF, Liu L, Wu MY and Yang HX: Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines. World J Gastroenterol 8: 203-207, 2002.
    • (2002) World J Gastroenterol , vol.8 , pp. 203-207
    • Hao, M.W.1    Liang, Y.R.2    Liu, Y.F.3    Liu, L.4    Wu, M.Y.5    Yang, H.X.6
  • 41
    • 1542374724 scopus 로고    scopus 로고
    • Expression of Egr-1, c-fos and cyclin D1 in esophageal cancer and its precursors
    • Wu MY, Zhuang CX, Yang HX and Liang YR: Expression of Egr-1, c-fos and cyclin D1 in esophageal cancer and its precursors. World J Gastroenterol 10: 476-480, 2004.
    • (2004) World J Gastroenterol , vol.10 , pp. 476-480
    • Wu, M.Y.1    Zhuang, C.X.2    Yang, H.X.3    Liang, Y.R.4
  • 42
    • 3042743883 scopus 로고    scopus 로고
    • Decreased expression of early growth response-1 and its role in uterine leiomyoma growth
    • Shozu M, Murakami K, Segawa T, et al: Decreased expression of early growth response-1 and its role in uterine leiomyoma growth. Cancer Res 64: 4677-4684, 2004.
    • (2004) Cancer Res , vol.64 , pp. 4677-4684
    • Shozu, M.1    Murakami, K.2    Segawa, T.3
  • 43
    • 30944446390 scopus 로고    scopus 로고
    • The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGF beta 1, PTEN, p53, and fibronectin
    • Baron V, Adamson ED, Calogero A, Ragona G and Mercola D: The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGF beta 1, PTEN, p53, and fibronectin. Cancer Gene Ther 13: 11-18, 2006.
    • (2006) Cancer Gene Ther , vol.13 , pp. 11-18
    • Baron, V.1    Adamson, E.D.2    Calogero, A.3    Ragona, G.4    Mercola, D.5
  • 44
    • 0034617216 scopus 로고    scopus 로고
    • The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251
    • Liu C, Yao J, Mercola D and Adamson E: The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251. J Biol Chem 275: 20315-20323, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 20315-20323
    • Liu, C.1    Yao, J.2    Mercola, D.3    Adamson, E.4
  • 45
    • 16644384180 scopus 로고    scopus 로고
    • siRNA-mediated down-regulation of survivin inhibits bladder cancer cell growth
    • Shuangli N, Fuessel S, Kotzsch M, et al: siRNA-mediated down-regulation of survivin inhibits bladder cancer cell growth. Int J Oncol 25: 1065-1071, 2004.
    • (2004) Int J Oncol , vol.25 , pp. 1065-1071
    • Shuangli, N.1    Fuessel, S.2    Kotzsch, M.3
  • 46
    • 0035881797 scopus 로고    scopus 로고
    • Epidermal growth factor and platelet-derived growth factor induce expression of Egr-1, a zinc finger transcription factor, in human malignant glioma cells
    • Kaufmann K and Thiel G: Epidermal growth factor and platelet-derived growth factor induce expression of Egr-1, a zinc finger transcription factor, in human malignant glioma cells. J Neurol Sci 189: 83-91, 2001.
    • (2001) J Neurol Sci , vol.189 , pp. 83-91
    • Kaufmann, K.1    Thiel, G.2
  • 47
    • 1542336952 scopus 로고    scopus 로고
    • Rational siRNA design for RNA interference
    • Reynolds A, Leake D and Boese Q: Rational siRNA design for RNA interference. Nat Biotechnol 22: 326-330, 2004.
    • (2004) Nat Biotechnol , vol.22 , pp. 326-330
    • Reynolds, A.1    Leake, D.2    Boese, Q.3


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