Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity

Biological Research

Volumn 38, Issue 2-3, 2005, Pages 163-178

  Inostroza, Juan ^a   Sáenz, Leonardo ^a   Calaf, Gloria ^b   Cabello, Gertrudis ^b   Parra, Eduardo ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE TARAPACÁ   (Chile)

Author keywords

Kinase JNK 1; Phosphatase PP4; Prostate cancer

Indexed keywords

CISPLATIN; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 4; PROTEIN C FOS; PROTEIN C JUN; PROTEIN PHOSPHATASE M3 6; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME REGULATION; ENZYME STABILITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; PROSTATE CARCINOMA; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 27544444555     PISSN: 07169760     EISSN: None     Source Type: Journal    
DOI: 10.4067/S0716-97602005000200006     Document Type: Article

References (58)

1. ADAMSON ED, WILEY LM (1997) The EGFR gene family in embryonic cell activities. Curr Top Dev Biol 34: 71-120
2. ADLER Y, FUCHS SY, KIM J, KRAFT A, KING MP, PELLING J, RONAI Z (1995) Jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells. Cell Growth Differ 6: 1437-1446
3. AHMED MM, CHENDIL D, LELE S, VENKATASUBBARAO K, DEY S, RITTER M, ROWLAND RG, MOHIUDDIN M (2001) Early growth response-1 gene: Potential radiation response gene marker in prostate cancer. Am J Clin Oncol 24: 500-505
4. BARON V, DUSS S, RHIM J, MERCOLA D (2003) Antisense to the early growth response-1 gene (EGR-1) inhibits prostate tumor development in TRAMP mice. Ann NY Acad Sci 1002: 197-216
5. BINTRUY B, SMEAL T, KARIN M (1991) Ha-ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature 351: 122-127
6. BLENIS J (1993) Signal transduction via the MAP kinase proceed at your own RISK. Proc Natl Acad Sci, USA 90: 5889-5892
7. BOCCO JL, BAHR A, GOETZ J, HAUSS C, KALLUNKI T, KEDINGER C, CHATTON B (1996) In vivo association of ATFa with JNK/SAP kinase activities. Oncogene 12: 1971-1980
8. BOST F, DEAN N, MCKAY R, MERCOLA D (1997) Activation of the Jun Kinase/Stress-Activated Protein Kinase Pathway is Required for EGF Autocrine Stimulated Growth of Human A549 Lung Carcinoma Cells. J Biol Chem 272: 33422-33429
9. BREWIS, ND (1993) PPX, a novel protein serine/threonine phosphatase localized to centrosomes. EMBO J 12: 987-996
10. BRUNET A, PAGES G, POUYSSEGUR J (1994) Constitutively active mutants of MAP kinase-kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts. Oncogene 9: 3379-3387
11. CHEN YR, SHRIVASTAVA A, TAN TH (2001) Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK-1 by hydrogen peroxide and pyrrolidine dithiocarbamate. Oncogene 20: 367-374
12. COBB MH. GOLDSMITH J (1995) How MAP kinases are regulated. J Biol Chem 270: 14843-14846
13. COHEN P, CHEN PTW (1989) Protein phosphatases come of age. J Biol Chem 264: 21435-38
14. COHEN PT (1990) Protein serine/phosphatases: An expanding family. FEBS let 268: 355-59
15. COHEN PT (1997) Novel protein serine/threonine phosphatase: Variety is the spice of life. Trends Biochem Sci 22: 245-251
16. DERIJARD B, HIBI M, WU I-H, BARRETT T, SU B, DENG T, KARIN M, DAVIS RJ (1994) JNK1, a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037
17. FANGER GR (1997) MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino terminal kinases. Curr Opin Genet Dev 7: 67-74
18. FOLTZ IN, GERL RE, WIELER JS, LUCKACH M, SALMON RA, SCHRADER JW (1998) Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli. J Biol Chem 273: 9344-9351
19. GROVER-BARDWICK A, ADAMSON E, MERCOLA D (1994) Transformation-specific pattern of phosphorylation of c-Jun, Jun-B, Jun-D and EGR-1 in v-sis transformed cells. Carcinogenesis 15: 1667-1674
20. GUAN KL, BROYLES SS, DIXON JE (1991) A Tyr/Ser protein phosphatase encoded by vaccinia virus. Nature 350: 359-362
21. GUPTA S, CAMPBELL D, DERIJARD B, DAVIS RJ (1995) Transcription factor ATF2 regulation by the JNK-1 signal transduction pathway. Science 267: 389-393
22. HANADA M, KOBAYASHI T, OHNISHI M, IKEDA S, WANG H, KATSURA K, YANAGAWA Y, KANAMARU A, TAMURA S (1998) Selective suppression of stress-activated protein kinase pathway by protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis. Exp Cell Res 230: 22-27
23. HANEDA M, SUGIMOTO T, KIKKAWA R (1999) Mitogen-activates protein kinase phosphatase: A negative regulator of the mitogen protein kinase cascade. Eur J Pharmacol 365: 1-7
24. HASHIMOTO K, HIGASHIYAMA S, ASADA H, HASHIMURA E, KOBAYASHI T, SUDO K, NAKAGAWA T, DAMM D, YOSHIKAWA K, TANIGUCHI N (1994) Heparin-binding epidermal growth factor-like growth factor is an authocrine growth factor for human keratinocytes. J Biol Chem 269(31): 20060-20066
25. HIBI M, LIN A, SMEAL T, MINDEN A, KARIN M (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes and Development 7: 2135-2148
26. IP YT, DAVIS RJ (1998) Signal transduction by the c-Jun N-terminal kinase (JNK) - From inflammation to development. Curr Opin Cell Biol 10: 205-219
27. JANKNECHT R, ERNST WH, PINGOUD V, NORDHEIM A (1993) Activation of ternary complex factor Elk-1 by MAP kinases. EMBO J 12: 5097-5104
28. JANKNECHT R, HUNTER T (1997) Convergence of MAP kinase pathways on the ternary complex factor Sap-1a. EMBO J 16: 1620-1627
29. KARIN, M (1995) The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486
30. KEETON AB, BORTOFF KD, BENNETT WL, FRANKLIN JL, VENABLE DY, MESSINA JL (2003) Insulin-regulated expression of Egr-1 and Krox 20: dependence on ERK1/2 and interaction with p38 and P13-kinase pathways. Endocrinology 144: 5402-5410
31. KEYSE SM (1998) Protein phosphatases and the regulation of MAP kinase activity. Semin Cell Dev Biol 9: 143-152
32. KLOEKER S, REED R, MCCONNELL JL, CHANG D, TRAN K, WESTPHAL RS, LAW BK, COLBRAN RJ, KAMOUN M, CAMPBELL KS, WADZINSKI BE (2003) Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein. Protein Expr Purif 31: 19-33
33. MINDEN A, LIN A, SMEAL T, BERIJARD B, COBB M, DAVIS R, KARIN M (1994) C-Jun and N-terminal phosphorylation correlates with activation of the JNK-1 subgroup but not the ERK subgroup of mitogen-activated protein kinases. Molec Cell Biol 14: 6683-6688
34. MORA GR, OLIVIER KR, CHEVILLE JC, MITCHELL RF JR, LINGLE WL, TINDALL DJ (2004) The cytoskeleton differentially localizes the early growth response gene-1 protein in cancer and benign cells of the prostate. Mol Cancer Res 2: 115-128
35. MUSTELIN T, VANG T, BOTTINI N (2005) Protein tyrosine phosphatases and the immune response. Nature Reviews Immunology 5: 43-57
36. MUDA M, THEODOSIOU A, RODRÍGUEZ N, BOSCHERT U, CAMPS M, GILLIERON C, DAVIES K, ARKINSTALL A (1996) The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases. J B Chem 271: 27205-27208
37. PAGES G, LENORMAND P, LALLEMAIN G, CHAMBARD JC, MELOCHE S, POUYSSEGUR J (1993) Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci, USA 90: 8319-8323
38. PARRA E, VARGA M, HEDLUND G, KALLAND T, DOHLSTEN M (1997) Co-stimulation by B7-1 and LFA-3 target distinct nuclear factors that bind to the Interleukin-2 promoter: B7-1 negatively regulates LFA-3 induced NF-AT DNA binding. Mol Cell Biol 17: 1314-1325
39. PARRA E, MCGUIRE K, HEDLUND G, DOHLSTEN M (1998) Overexpression of Re1A and c-Jun substitutes for B7-1 costimulation by targeting the CD28RE within the IL-2 promoter. The Journal of Immunology 160: 5374-5385
40. PIPAON C, CASADO JA, BUEREN JA, FERNÁNDEZ-LUNA JL (2004) Jun N-terminal kinase activity and early growth-response factor-1 gene expression are down-regulated in Fanconi anemia group A lymphoblasts. Blood 103: 128-132
41. POTAPOVA O, HAGHIGHI A, BOST F, LIU C, BIRRER MJ, GJERSET R, MERCOLA D (1997) The JNK1 stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin. J Biol Chem 272: 14041-14044
42. ROBINSON MJ, COBB MI (1996) Mitogen-activated protein kinase pathway. Curr Opin Cell Biol 9: 180-196
43. ROSETTE C, KARIN M (1996) Ultraviolet light and osmotic stress: Activation of the JNK-1 cascade through multiple growth factor and cytokine receptors. Science 274: 1194-1197
44. SÁNCHEZ I, HUGHES RT, MAYER BJ, YEE K, WOODGETT JR, ZON LI (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372: 794-798
45. SCHONTHAL AH (2001) Role of serine/threonine protein phosphatase 2 in cancer. Cancer Letters 170: 1-13
46. SHIOZAKI K, RUSSELL P (1995) Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast. EMBO J 14: 492-502
47. SMEAL T, BINETRUY B, MERCOLA D, GROVER-BARDWICK A, HEIDECKER G, RAPP UR, KARIN M (1992) Oncoprotein-mediated signaling cascade stimulates c-Jun activity by phosphorylation of serines 63 asid 73. Mol Cell Biol 12: 3507-3513
48. TATEISHI M, ISHIDA T, MITSUDOMI T, KANEKO S, SUGIMACHI K (1990) Immunohistochemical evidence of authocrine growth factors in adenocarcinoma of the human lung. Cancer Res 50: 7077-7080
49. TOURNIER C, WHITMARSH AJ, CAVANAGH J, BARRETT T, DAVIS RJ (1997) Mitogen-activated protein kinase-kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc Natl Acad Sci, USA 94: 7337-7342
50. VIROLLE T, ADAMSON ED, BARON V, BIRLE D, MERCOLA D, MUSTELIN T, DE BELLE I (2001) The Egr-1 transcription factor directly activates PTEN during irradiation-induced signaling. Nat Cell Biol 3: 1124-1128
51. VISSE E, INOSTROZA J, CABELLO G, PARRA E (2003) The MAP kinases are differently utilized by CD28 and CD2 adhesion pathways in super antigen-activated Jurkat T cells. Biol Res 36: 263-278
52. VLIESTRA RJ, VAN ALEWIJK DC, HERMANS KG, VAN STEENBRUGGE GJ, TRAPMAN J (1998). Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Research 58: 2720-2723
53. WIDMANN C, GERWINS P, JOHNSON NL, JARPE MB, JOHNSON GL (1998) MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol Cell Biol 18: 2416-2429
54. XU X, HEIDENREICH O, KITAJIMA I, MCGUIRE K, NEREMBERG M (1996) Constitutively activated JNK-1 is associated with HTLV-1 mediated tumorigenesis. Oncogene 13: 135-142
55. YEN C, DLIAW K, PODSYPANINA S, BOSE S, WANG I, PUC J, MILIARESIS C, ET AL. (1997) PTEN, putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate. Science 275: 1943-1947
56. YOU L, JAKOWLEW SB (1997) Identification of early growth response gene-1 (Egr-1) as a phorbol myristate acetate-induced gene in lung cancer cells by differential mRNA display. Am J Respir Cell Mol Biol 17: 617-624
57. ZAMBLE DB, LIPPARD SJ (1995) Cisplatin and DNA repair in cancer chemotherapy. Trends Biochem Sci 20: 435-439
58. ZHOU G, MIHINDUKULASURIYA KA, MACCORKLE-CHOSNEK RA, VAN HOOSER A, HU MC, BRINKLEY BR, TAN TH (2002) Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase. J Biol Chem 277: 6391-6398