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Volumn 43, Issue 4, 2010, Pages 385-395

Inhibition of cell proliferation by CD44: Akt is inactivated and EGR-1 is down-regulated

Author keywords

[No Author keywords available]

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; HERMES ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; SYNAPTOPHYSIN;

EID: 77954256636     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2010.00689.x     Document Type: Article
Times cited : (17)

References (37)
  • 1
    • 18244402390 scopus 로고    scopus 로고
    • Immunologic roles of hyaluronan
    • Mummert ME (2005) Immunologic roles of hyaluronan. Immunol. Res. 31, 189 206.
    • (2005) Immunol. Res. , vol.31 , pp. 189-206
    • Mummert, M.E.1
  • 2
    • 39049168749 scopus 로고    scopus 로고
    • Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44
    • Golshani R, Lopez L, Estrella V, Kramer M, Iida N, Lokeshwar VB (2008) Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44. Cancer Res. 68, 483 491.
    • (2008) Cancer Res. , vol.68 , pp. 483-491
    • Golshani, R.1    Lopez, L.2    Estrella, V.3    Kramer, M.4    Iida, N.5    Lokeshwar, V.B.6
  • 3
    • 3042775143 scopus 로고    scopus 로고
    • The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells
    • Gadhoum Z, Delaunay J, Maquarre E, Durand L, Lancereaux V, Qi J et al. (2004) The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells. Leuk. Lymphoma 45, 1501 1510.
    • (2004) Leuk. Lymphoma , vol.45 , pp. 1501-1510
    • Gadhoum, Z.1    Delaunay, J.2    Maquarre, E.3    Durand, L.4    Lancereaux, V.5    Qi, J.6
  • 5
    • 14644399741 scopus 로고    scopus 로고
    • Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells
    • Murphy JF, Lennon F, Steele C, Kelleher D, Fitzgerald D, Long AC (2005) Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells. FASEB J. 19, 446 448.
    • (2005) FASEB J. , vol.19 , pp. 446-448
    • Murphy, J.F.1    Lennon, F.2    Steele, C.3    Kelleher, D.4    Fitzgerald, D.5    Long, A.C.6
  • 6
    • 0036363322 scopus 로고    scopus 로고
    • Low molecular weight hyaluronan induces malignant mesothelioma cell (MMC) proliferation and haptotaxis: Role of CD44 receptor in MMC proliferation and haptotaxis
    • Nasreen N, Mohammed KA, Hardwick J, Van Horn RD, Sanders K, Kathuria H et al. (2002) Low molecular weight hyaluronan induces malignant mesothelioma cell (MMC) proliferation and haptotaxis: role of CD44 receptor in MMC proliferation and haptotaxis. Oncol. Res. 13, 71 78.
    • (2002) Oncol. Res. , vol.13 , pp. 71-78
    • Nasreen, N.1    Mohammed, K.A.2    Hardwick, J.3    Van Horn, R.D.4    Sanders, K.5    Kathuria, H.6
  • 8
    • 58149182887 scopus 로고    scopus 로고
    • CD45 down-regulates lck-mediated CD44 signaling and modulates actin rearrangement in T cells
    • Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P (2008) CD45 down-regulates lck-mediated CD44 signaling and modulates actin rearrangement in T cells. J. Immunol. 181, 7033 7043.
    • (2008) J. Immunol. , vol.181 , pp. 7033-7043
    • Wong, N.K.1    Lai, J.C.2    Birkenhead, D.3    Shaw, A.S.4    Johnson, P.5
  • 9
    • 1642461424 scopus 로고    scopus 로고
    • 2+ signaling leading to nitric oxide production and endothelial cell adhesion and proliferation
    • 2+ signaling leading to nitric oxide production and endothelial cell adhesion and proliferation. Exp. Cell Res. 295, 102 118.
    • (2004) Exp. Cell Res. , vol.295 , pp. 102-118
    • Singleton, P.A.1    Bourguignon, L.Y.2
  • 10
    • 19344377475 scopus 로고    scopus 로고
    • CD44v6 promotes proliferation by persisting activation of MAP kinases
    • Marhaba R, Bourouba M, Zoller M (2005) CD44v6 promotes proliferation by persisting activation of MAP kinases. Cell. Signal. 17, 961 973.
    • (2005) Cell. Signal. , vol.17 , pp. 961-973
    • Marhaba, R.1    Bourouba, M.2    Zoller, M.3
  • 11
    • 58149181980 scopus 로고    scopus 로고
    • Hyaluronan induces cell death in activated T cells through CD44
    • Ruffell B, Johnson P (2008) Hyaluronan induces cell death in activated T cells through CD44. J. Immunol. 181, 7044 7054.
    • (2008) J. Immunol. , vol.181 , pp. 7044-7054
    • Ruffell, B.1    Johnson, P.2
  • 12
    • 0035040968 scopus 로고    scopus 로고
    • Early growth response factor-1 mediates insulin-inducible vascular endothelial cell proliferation and regrowth after injury
    • Gousseva N, Kugathasan K, Chesterman CN, Khachigian LM (2001) Early growth response factor-1 mediates insulin-inducible vascular endothelial cell proliferation and regrowth after injury. J. Cell. Biochem. 81, 523 534.
    • (2001) J. Cell. Biochem. , vol.81 , pp. 523-534
    • Gousseva, N.1    Kugathasan, K.2    Chesterman, C.N.3    Khachigian, L.M.4
  • 13
    • 58149314576 scopus 로고    scopus 로고
    • Early growth response genes regulate B cell development, proliferation, and immune response
    • Gururajan M, Simmons A, Dasu T, Spear BT, Calulot C, Robertson DA et al. (2008) Early growth response genes regulate B cell development, proliferation, and immune response. J. Immunol. 181, 4590 4602.
    • (2008) J. Immunol. , vol.181 , pp. 4590-4602
    • Gururajan, M.1    Simmons, A.2    Dasu, T.3    Spear, B.T.4    Calulot, C.5    Robertson, D.A.6
  • 14
    • 58049099099 scopus 로고    scopus 로고
    • --channel is essential for LDL-induced cell proliferation via the activation of Erk1/2 and PI3k/Akt and the upregulation of egr-1 in human aortic smooth muscle cells
    • --channel is essential for LDL-induced cell proliferation via the activation of Erk1/2 and PI3k/Akt and the upregulation of egr-1 in human aortic smooth muscle cells. Mol. Cells 26, 468 473.
    • (2008) Mol. Cells , vol.26 , pp. 468-473
    • Heo, K.S.1    Ryoo, S.W.2    Kim, L.3    Nam, M.4    Baek, S.T.5    Lee, H.6
  • 15
    • 0036212895 scopus 로고    scopus 로고
    • Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of egr-1, a zinc finger transcriptional regulator
    • Kaufmann K, Thiel G (2002) Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of egr-1, a zinc finger transcriptional regulator. J. Cell. Biochem. 85, 381 391.
    • (2002) J. Cell. Biochem. , vol.85 , pp. 381-391
    • Kaufmann, K.1    Thiel, G.2
  • 16
    • 2942642252 scopus 로고    scopus 로고
    • Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1
    • Mitchell A, Dass CR, Sun LQ, Khachigian LM (2004) Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1. Nucleic Acids Res. 32, 3065 3069.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3065-3069
    • Mitchell, A.1    Dass, C.R.2    Sun, L.Q.3    Khachigian, L.M.4
  • 18
    • 0025013424 scopus 로고
    • An ELISA plate-based assay for hyaluronan using biotinylated proteoglycan G1 domain (HA-binding region)
    • Fosang AJ, Hey NJ, Carney SL, Hardingham TE (1990) An ELISA plate-based assay for hyaluronan using biotinylated proteoglycan G1 domain (HA-binding region). Matrix 10, 306 313.
    • (1990) Matrix , vol.10 , pp. 306-313
    • Fosang, A.J.1    Hey, N.J.2    Carney, S.L.3    Hardingham, T.E.4
  • 19
    • 0033522927 scopus 로고    scopus 로고
    • Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
    • Fujio Y, Walsh K (1999) Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J. Biol. Chem. 274, 16349 16354.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16349-16354
    • Fujio, Y.1    Walsh, K.2
  • 20
    • 40749125706 scopus 로고    scopus 로고
    • Re-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: Rescue of CD44-dependent cell death by cAMP
    • Abecassis I, Maes J, Carrier JL, Hillion J, Goodhardt M, Medjber K et al. (2008) Re-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: rescue of CD44-dependent cell death by cAMP. Leukemia 22, 511 520.
    • (2008) Leukemia , vol.22 , pp. 511-520
    • Abecassis, I.1    Maes, J.2    Carrier, J.L.3    Hillion, J.4    Goodhardt, M.5    Medjber, K.6
  • 21
    • 0035871299 scopus 로고    scopus 로고
    • The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
    • Morrison H, Sherman LS, Legg J, Banine F, Isacke C, Haipek CA et al. (2001) The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. Genes Dev. 15, 968 980.
    • (2001) Genes Dev. , vol.15 , pp. 968-980
    • Morrison, H.1    Sherman, L.S.2    Legg, J.3    Banine, F.4    Isacke, C.5    Haipek, C.A.6
  • 22
    • 0028233270 scopus 로고
    • Hyaluronate is costimulatory for human T cell effector functions and binds to CD44 on activated T cells
    • Galandrini R, Galluzzo E, Albi N, Grossi CE, Velardi A (1994) Hyaluronate is costimulatory for human T cell effector functions and binds to CD44 on activated T cells. J. Immunol. 153, 21 31.
    • (1994) J. Immunol. , vol.153 , pp. 21-31
    • Galandrini, R.1    Galluzzo, E.2    Albi, N.3    Grossi, C.E.4    Velardi, A.5
  • 23
    • 40049111897 scopus 로고    scopus 로고
    • Hyaluronan synthesis is required for IL-2-mediated T cell proliferation
    • Mahaffey CL, Mummert ME (2007) Hyaluronan synthesis is required for IL-2-mediated T cell proliferation. J. Immunol. 179, 8191 8199.
    • (2007) J. Immunol. , vol.179 , pp. 8191-8199
    • Mahaffey, C.L.1    Mummert, M.E.2
  • 24
    • 0037809237 scopus 로고    scopus 로고
    • Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes
    • Virolle T, Krones-Herzig A, Baron V, De Gregorio G, Adamson ED, Mercola D (2003) Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes. J. Biol. Chem. 278, 11802 11810.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11802-11810
    • Virolle, T.1    Krones-Herzig, A.2    Baron, V.3    De Gregorio, G.4    Adamson, E.D.5    Mercola, D.6
  • 25
    • 27544467453 scopus 로고    scopus 로고
    • Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells
    • Xiao D, Chinnappan D, Pestell R, Albanese C, Weber HC (2005) Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells. Cancer Res. 65, 9934 9942.
    • (2005) Cancer Res. , vol.65 , pp. 9934-9942
    • Xiao, D.1    Chinnappan, D.2    Pestell, R.3    Albanese, C.4    Weber, H.C.5
  • 26
    • 55549136709 scopus 로고    scopus 로고
    • PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells
    • Tanaka Y, Sekiguchi F, Hong H, Kawabata A (2008) PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. Biochem. Biophys. Res. Commun. 377, 622 626.
    • (2008) Biochem. Biophys. Res. Commun. , vol.377 , pp. 622-626
    • Tanaka, Y.1    Sekiguchi, F.2    Hong, H.3    Kawabata, A.4
  • 27
    • 0035421326 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma
    • Dong G, Chen Z, Li ZY, Yeh NT, Bancroft CC, Van Waes C (2001) Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma. Cancer Res. 61, 5911 5918.
    • (2001) Cancer Res. , vol.61 , pp. 5911-5918
    • Dong, G.1    Chen, Z.2    Li, Z.Y.3    Yeh, N.T.4    Bancroft, C.C.5    Van Waes, C.6
  • 28
    • 12844262373 scopus 로고    scopus 로고
    • A phosphatidyl-inositol-3-kinase-dependent anti-inflammatory pathway activated by Salmonella in epithelial cells
    • Huang FC, Li Q, Cherayil BJ (2005) A phosphatidyl-inositol-3-kinase- dependent anti-inflammatory pathway activated by Salmonella in epithelial cells. FEMS Microbiol. Lett. 243, 265 270.
    • (2005) FEMS Microbiol. Lett. , vol.243 , pp. 265-270
    • Huang, F.C.1    Li, Q.2    Cherayil, B.J.3
  • 29
  • 30
    • 34548260422 scopus 로고    scopus 로고
    • CD44 regulates cell migration in human colon cancer cells via lyn kinase and AKT phosphorylation
    • Subramaniam V, Vincent IR, Gardner H, Chan E, Dhamko H, Jothy S (2007) CD44 regulates cell migration in human colon cancer cells via lyn kinase and AKT phosphorylation. Exp. Mol. Pathol. 83, 207 215.
    • (2007) Exp. Mol. Pathol. , vol.83 , pp. 207-215
    • Subramaniam, V.1    Vincent, I.R.2    Gardner, H.3    Chan, E.4    Dhamko, H.5    Jothy, S.6
  • 31
    • 54949109808 scopus 로고    scopus 로고
    • PI3K/Akt: Getting it right matters
    • Franke TF (2008) PI3K/Akt: getting it right matters. Oncogene 27, 6473 6488.
    • (2008) Oncogene , vol.27 , pp. 6473-6488
    • Franke, T.F.1
  • 32
    • 0034604624 scopus 로고    scopus 로고
    • PKB/Akt interacts with inosine-5′ monophosphate dehydrogenase through its pleckstrin homology domain
    • Ingley E, Hemmings BA (2000) PKB/Akt interacts with inosine-5′ monophosphate dehydrogenase through its pleckstrin homology domain. FEBS Lett. 478, 253 259.
    • (2000) FEBS Lett. , vol.478 , pp. 253-259
    • Ingley, E.1    Hemmings, B.A.2
  • 33
    • 34948866760 scopus 로고    scopus 로고
    • Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression
    • Gao H, Yu Z, Bi D, Jiang L, Cui Y, Sun J et al. (2007) Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression. Mol. Cell. Biochem. 305, 35 44.
    • (2007) Mol. Cell. Biochem. , vol.305 , pp. 35-44
    • Gao, H.1    Yu, Z.2    Bi, D.3    Jiang, L.4    Cui, Y.5    Sun, J.6
  • 34
    • 0037938847 scopus 로고    scopus 로고
    • Interaction between src and a C-terminal proline-rich motif of akt is required for akt activation
    • Jiang T, Qiu Y (2003) Interaction between src and a C-terminal proline-rich motif of akt is required for akt activation. J. Biol. Chem. 278, 15789 15793.
    • (2003) J. Biol. Chem. , vol.278 , pp. 15789-15793
    • Jiang, T.1    Qiu, Y.2
  • 35
    • 57149109138 scopus 로고    scopus 로고
    • ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway
    • Hamai A, Meslin F, Benlalam H, Jalil A, Mehrpour M, Faure F et al. (2008) ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway. Cancer Res. 68, 9854 9864.
    • (2008) Cancer Res. , vol.68 , pp. 9854-9864
    • Hamai, A.1    Meslin, F.2    Benlalam, H.3    Jalil, A.4    Mehrpour, M.5    Faure, F.6
  • 36
    • 0033561561 scopus 로고    scopus 로고
    • Characterization of CD44 induction by IL-1: A critical role for egr-1
    • Fitzgerald KA, O'Neill LA (1999) Characterization of CD44 induction by IL-1: a critical role for egr-1. J. Immunol. 162, 4920 4927.
    • (1999) J. Immunol. , vol.162 , pp. 4920-4927
    • Fitzgerald, K.A.1    O'Neill, L.A.2
  • 37
    • 22844449992 scopus 로고    scopus 로고
    • Differential involvement of calmodulin-dependent protein kinase II-activated AP-1 and c-jun N-terminal kinase-activated EGR-1 signaling pathways in tumor necrosis factor-alpha and lipopolysaccharide-induced CD44 expression in human monocytic cells
    • Mishra JP, Mishra S, Gee K, Kumar A (2005) Differential involvement of calmodulin-dependent protein kinase II-activated AP-1 and c-jun N-terminal kinase-activated EGR-1 signaling pathways in tumor necrosis factor-alpha and lipopolysaccharide-induced CD44 expression in human monocytic cells. J. Biol. Chem. 280, 26825 26837.
    • (2005) J. Biol. Chem. , vol.280 , pp. 26825-26837
    • Mishra, J.P.1    Mishra, S.2    Gee, K.3    Kumar, A.4


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