The intra-molecular activation mechanisms of the dimeric metabotropic glutamate receptor 1 differ depending on the type of G proteins

Neuropharmacology

Volumn 61, Issue 4, 2011, Pages 832-841

  Tateyama, Michihiro ^a   Kubo, Yoshihiro ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Dual signaling; GIRK; Metabotropic glutamate receptor; TRPC3

Indexed keywords

CALCIUM ION; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; GLUTAMIC ACID; METABOTROPIC RECEPTOR 1;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL SURFACE; CONTROLLED STUDY; GENE CONSTRUCT; HUMAN; HUMAN CELL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; POINT MUTATION; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 79959934459     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.05.031     Document Type: Article

References (38)

1. H. Abe, T. Misaka, M. Tateyama, and Y. Kubo Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1alpha Mol. Cell. Neurosci. 23 2003 157 168 (Pubitemid 36703154)
2. C. Brock, N. Oueslati, S. Soler, L. Boudier, P. Rondard, and J.P. Pin Activation of a dimeric metabotropic glutamate receptor by inter-subunit rearrangement J. Biol. Chem. 282 2007 33000 33008 (Pubitemid 350161742)
3. A. Copani, C. Romano, V. Di Giorgi Gerevini, A. Nicosia, G. Casabona, M. Storto, V. Mutel, and F. Nicoletti Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors Brain Res. 867 2000 165 172 (Pubitemid 30317393)
4. G.K. Dhami, A.V. Babwah, R. Sterne-Marr, and S.S. Ferguson Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop J. Biol. Chem. 280 2005 24420 24427 (Pubitemid 40934526)
5. L.M. DiPilato, X. Cheng, and J. Zhang Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments Proc. Natl. Acad. Sci. U.S.A. 101 2004 16513 16518 (Pubitemid 39557744)
6. E. Doumazane, P. Scholler, J.M. Zwier, E. Trinquet, P. Rondard, and J.P. Pin A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors FASEB J 2010
7. T.A. Dunn, C.T. Wang, M.A. Colicos, M. Zaccolo, L.M. DiPilato, J. Zhang, R.Y. Tsien, and M.B. Feller Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades J. Neurosci. 26 2006 12807 12815 (Pubitemid 44904576)
8. A. Francesconi, and R.M. Duvoisin Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation J. Biol. Chem. 273 1998 5615 5624 (Pubitemid 28124031)
9. 2+ pathway by phosphorylation of the receptor-G protein-coupling domain Proc. Natl. Acad. Sci. U.S.A. 97 2000 6185 6190 (Pubitemid 30367544)
10. T. Galvez, B. Duthey, J. Kniazeff, J. Blahos, G. Rovelli, B. Bettler, L. Prezeau, and J.P. Pin Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function Embo J. 20 2001 2152 2159 (Pubitemid 32410585)
11. Y. Han, I.S. Moreira, E. Urizar, H. Weinstein, and J.A. Javitch Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation Nat. Chem. Biol. 5 2009 688 695
12. J. Hartmann, E. Dragicevic, H. Adelsberger, H.A. Henning, M. Sumser, J. Abramowitz, R. Blum, A. Dietrich, M. Freichel, V. Flockerzi, L. Birnbaumer, and A. Konnerth TRPC3 channels are required for synaptic transmission and motor coordination Neuron 59 2008 392 398
13. A.A. Jensen, P.O. Sheppard, P.J. O'Hara, P. Krogsgaard-Larsen, and H. Brauner-Osborne The role of Arg(78) in the metabotropic glutamate receptor mGlu(1) for agonist binding and selectivity Eur. J. Pharmacol. 397 2000 247 253 (Pubitemid 30323775)
14. P.J. Kammermeier C-terminal deletion of metabotropic glutamate receptor 1 selectively abolishes coupling to Galphaq Eur. J. Pharmacol. 627 2009 63 68
15. P.J. Kammermeier, and J. Yun Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits J. Pharmacol. Exp. Ther. 312 2005 502 508 (Pubitemid 40189546)
16. 2+ channel J. Biol. Chem. 278 2003 25101 25108 (Pubitemid 37548674)
17. J. Kniazeff, A.S. Bessis, D. Maurel, H. Ansanay, L. Prezeau, and J.P. Pin Closed state of both binding domains of homodimeric mGlu receptors is required for full activity Nat. Struct. Mol. Biol. 11 2004 706 713 (Pubitemid 39014495)
18. N. Kunishima, Y. Shimada, Y. Tsuji, T. Sato, M. Yamamoto, T. Kumasaka, S. Nakanishi, H. Jingami, and K. Morikawa Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor Nature 407 2000 971 977
19. P. Malherbe, F. Knoflach, C. Broger, S. Ohresser, C. Kratzeisen, G. Adam, H. Stadler, J.A. Kemp, and V. Mutel Identification of essential residues involved in the glutamate binding pocket of the group II metabotropic glutamate receptor Mol. Pharmacol. 60 2001 944 954 (Pubitemid 33027429)
20. J. Mao, X. Wang, F. Chen, R. Wang, A. Rojas, Y. Shi, H. Piao, and C. Jiang Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C Proc. Natl. Acad. Sci. U.S.A. 101 2004 1087 1092 (Pubitemid 38160588)
21. M. Margeta-Mitrovic, Y.N. Jan, and L.Y. Jan Ligand-induced signal transduction within heterodimeric GABA(B) receptor Proc. Natl. Acad. Sci. U.S.A. 98 2001 14643 14648 (Pubitemid 33121445)
22. S. Matsushita, H. Nakata, Y. Kubo, and M. Tateyama Ligand-induced rearrangements of the GABA(B) receptor revealed by fluorescence resonance energy transfer J. Biol. Chem. 285 2010 10291 10299
23. D. Maurel, L. Comps-Agrar, C. Brock, M.L. Rives, E. Bourrier, M.A. Ayoub, H. Bazin, N. Tinel, T. Durroux, L. Prezeau, E. Trinquet, and J.P. Pin Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization Nat. Methods 5 2008 561 567 (Pubitemid 351761765)
24. T. Muto, D. Tsuchiya, K. Morikawa, and H. Jingami Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc. Natl. Acad. Sci. U.S.A. 104 2007 3759 3764 (Pubitemid 47189144)
25. F. Nicoletti, J. Bockaert, G.L. Collingridge, P.J. Conn, F. Ferraguti, D.D. Schoepp, J.T. Wroblewski, and J.P. Pin Metabotropic glutamate receptors: from the workbench to the bedside Neuropharmacology 2010
26. P.S. Park, S. Filipek, J.W. Wells, and K. Palczewski Oligomerization of G protein-coupled receptors: past, present, and future Biochemistry 43 2004 15643 15656 (Pubitemid 39665065)
27. J.P. Pin, T. Galvez, and L. Prezeau Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors Pharmacol. Ther. 98 2003 325 354 (Pubitemid 36638547)
28. M.J. Robbins, F. Ciruela, A. Rhodes, and R.A. McIlhinney Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1alpha J. Neurochem. 72 1999 2539 2547 (Pubitemid 29242206)
29. T. Sato, Y. Shimada, N. Nagasawa, S. Nakanishi, and H. Jingami Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state J. Biol. Chem. 278 2003 4314 4321 (Pubitemid 36801169)
30. J.V. Selkirk, G.W. Price, S.R. Nahorski, and R.A. Challiss Cell type-specific differences in the coupling of recombinant mGlu1alpha receptors to endogenous G protein sub-populations Neuropharmacology 40 2001 645 656 (Pubitemid 32323987)
31. D.J. Sheffler, and P.J. Conn Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells Neuropharmacology 55 2008 419 427
32. Y. Sugiyama, S.Y. Kawaguchi, and T. Hirano mGluR1-mediated facilitation of long-term potentiation at inhibitory synapses on a cerebellar Purkinje neuron Eur. J. Neurosci. 27 2008 884 896 (Pubitemid 351365174)
33. M. Tateyama, H. Abe, H. Nakata, O. Saito, and Y. Kubo Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha Nat. Struct. Mol. Biol. 11 2004 637 642 (Pubitemid 38823530)
34. M. Tateyama, and Y. Kubo Dual signaling is differentially activated by different active states of the metabotropic glutamate receptor 1alpha Proc. Natl. Acad. Sci. U.S.A. 103 2006 1124 1128 (Pubitemid 43212232)
35. M. Tateyama, and Y. Kubo Coupling profile of the metabotropic glutamate receptor 1alpha is regulated by the C-terminal domain Mol. Cell. Neurosci. 34 2007 445 452 (Pubitemid 46330046)
36. M. Tateyama, and Y. Kubo Regulatory role of C-terminus in the G-protein coupling of the metabotropic glutamate receptor 1 J. Neurochem. 107 2008 1036 1046
37. Y. Tsuji, Y. Shimada, T. Takeshita, N. Kajimura, S. Nomura, N. Sekiyama, J. Otomo, J. Usukura, S. Nakanishi, and H. Jingami Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1 J. Biol. Chem. 275 2000 28144 28151
38. T. Yamashita, A. Terakita, T. Kai, and Y. Shichida Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation J. Neurochem. 106 2008 850 859