Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1α

Molecular and Cellular Neuroscience

Volumn 23, Issue 2, 2003, Pages 157-168

  Abe, Hideki ^a,b,d   Misaka, Takumi ^a,c   Tateyama, Michihiro ^a,b   Kubo, Yoshihiro ^a,b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GADOLINIUM; GLUTAMIC ACID; HOMER PROTEIN; ISOPROTEIN; METABOTROPIC RECEPTOR; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING;

EID: 0038579336     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-7431(03)00052-6     Document Type: Article

References (32)

1. Aiba A., Chen C., Herrup K., Rosenmund C., Stevens C.F., Tonegawa S. Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice. Cell. 79:1994;365-375.
2. Aiba A., Kano M., Chen C., Stanton M.E., Fox G.D., Herrup K., Zwingman T.A., Tonegawa S. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell. 79:1994;377-388.
3. Ango F., Prezeau L., Muller T., Tu J.C., Xiao B., Worley P.F., Pin J.P., Bockaert J., Fagni L. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature. 411:2001;962-965.
4. Anwyl R. Metabotropic glutamate receptors electrophysiological properties and role in plasticity . Brain Res. Brain Res. Rev. 29:1999;83-120.
5. Brakeman P.R., Lanahan A.A., O'Brien R., Roche K., Barnes C.A., Huganir R.L., Worley P.F. Homer a protein that selectively binds metabotropic glutamate receptors . Nature. 386:1997;284-288.
6. Ciruela F., Soloviev M.M., Chan W.Y., McIlhinney R.A. Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type evidence for an anchoring function . Mol. Cell. Neurosci. 15:2000;36-50.
7. Ciruela F., Soloviev M.M., McIlhinney R.A. Co-expression of metabotropic glutamate receptor type with homer-1a/Vesl-1S increases the cell surface expression of the receptor. Biochem. J. 341:1999;795-803.
8. Conquet F., Bashir Z.I., Davies C.H., Daniel H., Ferraguti F., Bordi F., Franz-Bacon K., Reggiani A., Matarese V., Conde F., Collingridge G.L., Crepel F. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature. 372:1994;237-243.
9. Jensen A.A., Sheppard P.O., Jensen L.B., O'Hara P.J., Brauner-Osborne H. Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1 noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor . J. Biol. Chem. 276:2001;10110-10118.
10. Kato A., Ozawa F., Saitoh Y., Fukazawa Y., Sugiyama H., Inokuchi K. Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors. J. Biol. Chem. 273:1998;23969-23975.
11. Kato A., Ozawa F., Saitoh Y., Hirai K., Inokuchi K. vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis. FEBS Lett. 412:1997;183-189.
12. 2+ sensing function of the metabotropic glutamate receptors. Science. 279:1998;1722-1725.
13. Kunishima N., Shimada Y., Tsuji Y., Sato T., Yamamoto M., Kumasaka T., Nakanishi S., Jingami H., Morikawa K. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature. 407:2000;971-977.
14. Masu M., Tanabe Y., Tsuchida K., Shigemoto R., Nakanishi S. Sequence and expression of a metabotropic glutamate receptor. Nature. 349:1991;760-765.
15. 2+ sensitivity of mGluR1 associated with persistent glutamate response in transfected CHO cells. Recep. Chann. 7:2000;25-40.
16. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 258:1992;597-603.
17. Nakanishi S. Metabotropic glutamate receptors synaptic transmission, modulation, and plasticity . Neuron. 13:1994;1031-1037.
18. 2+ in single cells. J. Biol. Chem. 276:2001;19286-19293.
19. Niwa H., Yamamura K., Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 108:1991;193-199.
20. O'Hara P.J., Sheppard P.O., Thogersen H., Venezia D., Haldeman B.A., McGrane V., Houamed K.M., Thomsen C., Gilbert T.L., Mulvihill E.R. The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins. Neuron. 11:1993;41-52.
21. Ray K., Hauschild B.C. Cys-140 is critical for metabotropic glutamate receptor-1 dimerization. J. Biol. Chem. 275:2000;34245-34251.
22. Roche K.W., Tu J.C., Petralia R.S., Xiao B., Wenthold R.J., Worley P.F. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors. J. Biol. Chem. 274:1999;25953-25957.
23. Romano C., Miller J.K., Hyrc K., Dikranian S., Mennerick S., Takeuchi Y., Goldberg M.P., O'Malley K.L. Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization. Mol. Pharmacol. 59:2001;46-53.
24. 2+ on type 1alpha metabotropic glutamate receptor-mediated signalling. Neuropharmacology. 37:1998;273-276.
25. Shigemoto R., Abe T., Nomura S., Nakanishi S., Hirano T. Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells. Neuron. 12:1994;1245-1255.
26. Sugiyama H., Ito I., Hirono C. A new type of glutamate receptor linked to inositol phospholipid metabolism. Nature. 325:1987;531-533.
27. Tadokoro S., Tachibana T., Imanaka T., Nishida W., Sobue K. Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering. Proc. Natl. Acad. Sci. USA. 96:1999;13801-13806.
28. 3+. Proc. Natl. Acad. Sci. USA. 99:2002;2660-2665.
29. Tsuji Y., Shimada Y., Takeshita T., Kajimura N., Nomura S., Sekiyama N., Otomo J., Usukura J., Nakanishi S., Jingami H. Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1. J. Biol. Chem. 275:2000;28144-28151.
30. Tu J.C., Xiao B., Yuan J.P., Lanahan A.A., Leoffert K., Li M., Linden D.J., Worley P.F. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron. 21:1998;717-726.
31. Xiao B., Tu J.C., Petralia R.S., Yuan J.P., Doan A., Breder C.D., Ruggiero A., Lanahan A.A., Wenthold R.J., Worley P.F. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron. 21:1998;707-716.
32. Xiao B., Tu J.C., Worley P.F. Homer a link between neural activity and glutamate receptor function . Curr. Opin. Neurobiol. 10:2000;370-374.