메뉴 건너뛰기




Volumn 7, Issue 3, 2011, Pages 360-367

Emerging role of complement in ocular diseases

Author keywords

Age related macular degeneration; Complement regulatory proteins; Complement system; Diabetic retinopathy; Glaucoma; Uveitis

Indexed keywords

CD59 ANTIGEN; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4 BINDING PROTEIN; COMPLEMENT COMPONENT C5A; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I; COMPLEMENT MEMBRANE ATTACK COMPLEX; DECAY ACCELERATING FACTOR; GLUCOSE; LECTIN; MEMBRANE COFACTOR PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN; STEROID;

EID: 79959925216     PISSN: 15733955     EISSN: 1875631X     Source Type: Journal    
DOI: 10.2174/157339511796196656     Document Type: Review
Times cited : (4)

References (97)
  • 1
    • 0006820249 scopus 로고
    • Complement
    • In: Parker CW Ed, Philadelphia, WB Saunders
    • Atkinson JP, Frank MM. Complement. In: Parker CW Ed, Clinical Immunology. Philadelphia, WB Saunders. 1980; 219-71.
    • (1980) Clinical Immunology , pp. 219-271
    • Atkinson, J.P.1    Frank, M.M.2
  • 3
    • 12444343243 scopus 로고    scopus 로고
    • The complement system
    • In: Morgan BP and Harris CL Eds, San Diego, Academic
    • Morgan BP, Harris CL. The complement system. In: Morgan BP and Harris CL Eds, Complement regulatory proteins. San Diego, Academic. 1999; 1-13.
    • (1999) Complement Regulatory Proteins , pp. 1-13
    • Morgan, B.P.1    Harris, C.L.2
  • 4
    • 0033659939 scopus 로고    scopus 로고
    • Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59
    • Sohn JH, Kaplan HJ, Suk HJ, Bora PS, Bora NS. Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59. Invest Ophthalmol Vis Sci 2000; 41(13): 4195-202.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.13 , pp. 4195-4202
    • Sohn, J.H.1    Kaplan, H.J.2    Suk, H.J.3    Bora, P.S.4    Bora, N.S.5
  • 5
    • 0028329185 scopus 로고
    • Complement inhibitor of rat cell membrane resembling mouse Crry/p65
    • Takizawa H, Okada N, Okada H. Complement inhibitor of rat cell membrane resembling mouse Crry/p65. J Immunol 1994; 152: 3032-8.
    • (1994) J Immunol , vol.152 , pp. 3032-3038
    • Takizawa, H.1    Okada, N.2    Okada, H.3
  • 7
    • 0020673599 scopus 로고
    • Hemolytic complement activity in aqueous humor
    • Mondino BJ, Rao H. Hemolytic complement activity in aqueous humor. Arch Ophthalmol 1983; 101(3): 465-8.
    • (1983) Arch Ophthalmol , vol.101 , Issue.3 , pp. 465-468
    • Mondino, B.J.1    Rao, H.2
  • 9
    • 0033775686 scopus 로고    scopus 로고
    • Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins
    • Sohn JH, Kaplan HJ, Suk HJ, Bora PS, Bora NS. Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins. Invest Ophthalmol Vis Sci 2000; 41(11): 3492-3502.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.11 , pp. 3492-3502
    • Sohn, J.H.1    Kaplan, H.J.2    Suk, H.J.3    Bora, P.S.4    Bora, N.S.5
  • 11
    • 0025291151 scopus 로고
    • Expression of two molecular forms of the complement decay-accelerating factor in the eye and lacrimal gland
    • Lass JH, Walter EI, Burris TE, et al. Expression of two molecular forms of the complement decay-accelerating factor in the eye and lacrimal gland. Invest Ophthalmol Vis Sci 1990; 31(6): 1136-48.
    • (1990) Invest Ophthalmol Vis Sci , vol.31 , Issue.6 , pp. 1136-1148
    • Lass, J.H.1    Walter, E.I.2    Burris, T.E.3
  • 12
    • 0037324434 scopus 로고    scopus 로고
    • Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells
    • Sohn JH, Bora PS, Suk HJ, Molina H, Kaplan HJ, Bora NS. Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med 2003; 9(2): 206-12.
    • (2003) Nat Med , vol.9 , Issue.2 , pp. 206-212
    • Sohn, J.H.1    Bora, P.S.2    Suk, H.J.3    Molina, H.4    Kaplan, H.J.5    Bora, N.S.6
  • 14
    • 0031402682 scopus 로고    scopus 로고
    • Changing trends in the etiologic diagnosis of uveitis
    • Silverstein AM. Changing trends in the etiologic diagnosis of uveitis. Doc Ophthalmol 1997; 94(1-2): 25-37.
    • (1997) Doc Ophthalmol , vol.94 , Issue.1-2 , pp. 25-37
    • Silverstein, A.M.1
  • 15
    • 33947500766 scopus 로고    scopus 로고
    • Intraocular diseases - anterior uveitis
    • Bora NS, Kaplan HJ. Intraocular diseases - anterior uveitis. Chem Immunol Allergy 2007; 92: 213-20.
    • (2007) Chem Immunol Allergy , vol.92 , pp. 213-220
    • Bora, N.S.1    Kaplan, H.J.2
  • 16
    • 0032408878 scopus 로고    scopus 로고
    • Basic pathogenic mechanisms operating in experimental models of acute anterior uveitis
    • Smith JR, Hart PH, Williams KA. Basic pathogenic mechanisms operating in experimental models of acute anterior uveitis. Immunol Cell Biol 1998; 76(6): 497-512.
    • (1998) Immunol Cell Biol , vol.76 , Issue.6 , pp. 497-512
    • Smith, J.R.1    Hart, P.H.2    Williams, K.A.3
  • 17
    • 0017662528 scopus 로고
    • Experimental allergic uveitis. Isolation, characterization, and localization of a soluble uveitopathogenic antigen from bovine retina
    • Wacker WB, Donoso LA, Kalsow CM, Yankeelov JA, Organisciak DT. Experimental allergic uveitis. Isolation, characterization, and localization of a soluble uveitopathogenic antigen from bovine retina. J Immunol 1977; 119: 1949-58.
    • (1977) J Immunol , vol.119 , pp. 1949-1958
    • Wacker, W.B.1    Donoso, L.A.2    Kalsow, C.M.3    Yankeelov, J.A.4    Organisciak, D.T.5
  • 18
    • 0027512153 scopus 로고
    • The preparation of uveitogenic melanin
    • Experimental autoimmune anterior uveitis
    • Broekhuyse RM, Kuhlmann ED. Experimental autoimmune anterior uveitis. The preparation of uveitogenic melanin. Invest Ophthalmol Vis Sci 1993; 34: 698-700.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 698-700
    • Broekhuyse, R.M.1    Kuhlmann, E.D.2
  • 19
    • 0028956306 scopus 로고
    • Induction with melanin-associated antigen from the iris and ciliary body
    • Experimental autoimmune anterior uveitis
    • [Bora NS, Kim MC, Kabeer NH, et al. Experimental autoimmune anterior uveitis. Induction with melanin-associated antigen from the iris and ciliary body. Invest Ophthalmol Vis Sci 1995; 36(6): 1056-66.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , Issue.6 , pp. 1056-1066
    • Bora, N.S.1    Kim, M.C.2    Kabeer, N.H.3
  • 20
    • 0029091958 scopus 로고
    • Immunohistochemical studies in melanin associated antigen (MAA) induced experimental autoimmune anterior uveitis (EAAU)
    • Kim MC, Kabeer NH, Tandhasetti MT, Kaplan HJ, Bora NS. Immunohistochemical studies in melanin associated antigen (MAA) induced experimental autoimmune anterior uveitis (EAAU). Curr. Eye Res 1995; 14: 703-710.
    • (1995) Curr. Eye Res , vol.14 , pp. 703-710
    • Kim, M.C.1    Kabeer, N.H.2    Tandhasetti, M.T.3    Kaplan, H.J.4    Bora, N.S.5
  • 21
    • 0030930846 scopus 로고    scopus 로고
    • Induction of experimental autoimmune anterior uveitis by a selfantigen: Melanin complex without adjuvant
    • Bora NS, Woon MD, Tandhasetti MT, Cirrito TP, Kaplan HJ. Induction of experimental autoimmune anterior uveitis by a selfantigen: melanin complex without adjuvant. Invest Ophthalmol Vis Sci 1997; 38: 2171-5.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 2171-2175
    • Bora, N.S.1    Woon, M.D.2    Tandhasetti, M.T.3    Cirrito, T.P.4    Kaplan, H.J.5
  • 22
    • 2442691583 scopus 로고    scopus 로고
    • Type I collagen is the autoantigen in experimental autoimmune anterior uveitis
    • Bora, NS, Sohn JH, Kang SG, et al. Type I collagen is the autoantigen in experimental autoimmune anterior uveitis. J Immunol 2004; 172(11): 7086-94.
    • (2004) J Immunol , vol.172 , Issue.11 , pp. 7086-7094
    • Bora, N.S.1    Sohn, J.H.2    Kang, S.G.3
  • 23
    • 33645404385 scopus 로고    scopus 로고
    • The complement system plays a critical role in the development of experimental autoimmune anterior uveitis
    • Jha P, Sohn JH, Xu Q, et al. The complement system plays a critical role in the development of experimental autoimmune anterior uveitis. Invest Ophthalmol Vis Sci 2006; 47: 1030-8.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 1030-1038
    • Jha, P.1    Sohn, J.H.2    Xu, Q.3
  • 24
    • 33744906052 scopus 로고    scopus 로고
    • Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU)
    • Jha P, Sohn JH, Xu Q, et al. Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU). J Immunol 2006; 176: 7221-31.
    • (2006) J Immunol , vol.176 , pp. 7221-7231
    • Jha, P.1    Sohn, J.H.2    Xu, Q.3
  • 26
    • 55349098514 scopus 로고    scopus 로고
    • Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ Tregulatory cells
    • Matta B, Jha P, Bora PS, Bora NS. Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ Tregulatory cells. Am J Pathol 2008; 173: 1440-54.
    • (2008) Am J Pathol , vol.173 , pp. 1440-1454
    • Matta, B.1    Jha, P.2    Bora, P.S.3    Bora, N.S.4
  • 27
    • 71449105733 scopus 로고    scopus 로고
    • Proteolytic cleavage of type I collagen generates an autoantigen in autoimmune uveitis
    • Jha P, Manickam B, Matta B, Bora PS, Bora NS. Proteolytic cleavage of type I collagen generates an autoantigen in autoimmune uveitis. J Biol Chem 2009; 284(45): 31401-31411.
    • (2009) J Biol Chem , vol.284 , Issue.45 , pp. 31401-11
    • Jha, P.1    Manickam, B.2    Matta, B.3    Bora, P.S.4    Bora, N.S.5
  • 28
    • 0019304038 scopus 로고
    • Endotoxininduced uveitis in rats as a model for human disease
    • Rosenbaum JT, McDevitt HO, Guss RB, Egbert PR. Endotoxininduced uveitis in rats as a model for human disease. Nature 1980; 286: 611-3.
    • (1980) Nature , vol.286 , pp. 611-613
    • Rosenbaum, J.T.1    McDevitt, H.O.2    Guss, R.B.3    Egbert, P.R.4
  • 30
    • 0018861226 scopus 로고
    • Effects of various pharmacologic agents on allergic inflammation of the eye. The roles of chemical mediators in ocular inflammation
    • Okada M, Shimada K. Effects of various pharmacologic agents on allergic inflammation of the eye. The roles of chemical mediators in ocular inflammation. Invest Ophthalmol Vis Sci 1980; 19(2): 176-81.
    • (1980) Invest Ophthalmol Vis Sci , vol.19 , Issue.2 , pp. 176-181
    • Okada, M.1    Shimada, K.2
  • 32
    • 31344433995 scopus 로고    scopus 로고
    • Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis
    • Read RW, Szalai AJ, Vogt SD, McGwin G, Barnum SR. Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis. Exp Eye Res 2006; 82(3): 389-94.
    • (2006) Exp Eye Res , vol.82 , Issue.3 , pp. 389-394
    • Read, R.W.1    Szalai, A.J.2    Vogt, S.D.3    McGwin, G.4    Barnum, S.R.5
  • 33
    • 68349083457 scopus 로고    scopus 로고
    • Role of DAF in protecting against T-cell autoreactivity that leads to experimental autoimmune uveitis
    • An F, Li Q, Tu Z, et al. Role of DAF in protecting against T-cell autoreactivity that leads to experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 2009; 50(8): 3778-82.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.8 , pp. 3778-3782
    • An, F.1    Li, Q.2    Tu, Z.3
  • 34
    • 79960020027 scopus 로고    scopus 로고
    • Word Health Organization
    • May
    • Visual impairment and blindness, Word Health Organization, Fact Sheet No 282, May 2009.
    • (2009) Fact Sheet No , pp. 282
    • Impairment, V.1
  • 36
    • 11144354339 scopus 로고    scopus 로고
    • Eye Diseases Prevalence Research Group. Prevalence of age-related macular degeneration in the United States
    • Friedman DS, O'Colmain BJ, Muñoz B, et al. Eye Diseases Prevalence Research Group. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004; 122(4): 564-72.
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Muñoz, B.3
  • 37
    • 34548303819 scopus 로고    scopus 로고
    • The role of complement system in ocular diseases including uveitis and macular degeneration
    • Jha P, Bora PS, Bora NS. The role of complement system in ocular diseases including uveitis and macular degeneration. Mol Immunol 2007; 44(16): 3901-8.
    • (2007) Mol Immunol , vol.44 , Issue.16 , pp. 3901-3908
    • Jha, P.1    Bora, P.S.2    Bora, N.S.3
  • 39
    • 0033895534 scopus 로고    scopus 로고
    • Retinal and choroidal neovascularization
    • Campochiaro PA. Retinal and choroidal neovascularization. J Cell Physiol 2000; 184(3): 301-10.
    • (2000) J Cell Physiol , vol.184 , Issue.3 , pp. 301-310
    • Campochiaro, P.A.1
  • 40
    • 10844231850 scopus 로고    scopus 로고
    • Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization
    • Bora PS, Sohn JH, Cruz JM, et al. Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization. J Immunol 2005; 174(1): 491-7.
    • (2005) J Immunol , vol.174 , Issue.1 , pp. 491-497
    • Bora, P.S.1    Sohn, J.H.2    Cruz, J.M.3
  • 41
    • 33745670172 scopus 로고    scopus 로고
    • The genetics of age-related macular degeneration: A review of progress to date
    • Haddad S, Chen CA, Santangelo SL, Seddon JM. The genetics of age-related macular degeneration: a review of progress to date. Surv Ophthalmol 2006; 51(4): 316-63.
    • (2006) Surv Ophthalmol , vol.51 , Issue.4 , pp. 316-363
    • Haddad, S.1    Chen, C.A.2    Santangelo, S.L.3    Seddon, J.M.4
  • 42
    • 33144459399 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of age-related macular degeneration
    • Donoso LA, Kim D, Frost A, Callahan A, Hageman G. The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2006; 51(2): 137-52.
    • (2006) Surv Ophthalmol , vol.51 , Issue.2 , pp. 137-152
    • Donoso, L.A.1    Kim, D.2    Frost, A.3    Callahan, A.4    Hageman, G.5
  • 43
    • 0025324036 scopus 로고
    • Pathogenesis of laserinduced choroidal subretinal neovascularization
    • Miller H, Miller B, Ishibashi T, Ryan SJ. Pathogenesis of laserinduced choroidal subretinal neovascularization. Invest Ophthalmol Vis Sci 1990; 31(5): 899-908.
    • (1990) Invest Ophthalmol Vis Sci , vol.31 , Issue.5 , pp. 899-908
    • Miller, H.1    Miller, B.2    Ishibashi, T.3    Ryan, S.J.4
  • 44
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science 2005; 308: 385-9.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 45
    • 33846037715 scopus 로고    scopus 로고
    • A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors
    • Schaumberg DA, Hankinson SE, Guo Q, Rimm E, Hunter DJ. A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors. Arch Ophthalmol 2007; 125(1): 55-62.
    • (2007) Arch Ophthalmol , vol.125 , Issue.1 , pp. 55-62
    • Schaumberg, D.A.1    Hankinson, S.E.2    Guo, Q.3    Rimm, E.4    Hunter, D.J.5
  • 46
    • 1842478123 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of age-related macular degeneration
    • Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 2004; 122(4): 598-614.
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 598-614
    • Zarbin, M.A.1
  • 48
    • 42449090245 scopus 로고    scopus 로고
    • The role of complement in ocular pathology
    • Bora NS, Jha P, Bora PS. The role of complement in ocular pathology. Semin Immunopathol 2008; 30(2): 85-95.
    • (2008) Semin Immunopathol , vol.30 , Issue.2 , pp. 85-95
    • Bora, N.S.1    Jha, P.2    Bora, P.S.3
  • 49
    • 33144488589 scopus 로고    scopus 로고
    • Drusen complement component C3a and C5a promote choroidal neovascularization
    • Nozaki M, Raisier BJ, Sakurai E, et al. Drusen complement component C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci USA. 2006; 103: 2328-33.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2328-2333
    • Nozaki, M.1    Raisier, B.J.2    Sakurai, E.3
  • 50
    • 34848886930 scopus 로고    scopus 로고
    • Loss of self-control in the complement system and innate autoreactivity
    • Meri S. Loss of self-control in the complement system and innate autoreactivity. Ann N Y Acad Sci 2007; 1109: 93-105.
    • (2007) Ann N Y Acad Sci , vol.1109 , pp. 93-105
    • Meri, S.1
  • 51
    • 33846507393 scopus 로고    scopus 로고
    • CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration
    • Bora NS, Kaliappan S, Jha P, et al. CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration. J Immunol 2007; 178(3): 1783-90.
    • (2007) J Immunol , vol.178 , Issue.3 , pp. 1783-1790
    • Bora, N.S.1    Kaliappan, S.2    Jha, P.3
  • 52
    • 62649135260 scopus 로고    scopus 로고
    • Complement activation by bisretinoid constituents of RPE lipofuscin
    • Zhou J, Kim SR, Westlund BS, Sparrow JR. Complement activation by bisretinoid constituents of RPE lipofuscin. Invest Ophthalmol Vis Sci 2009; 50(3): 1392-9.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.3 , pp. 1392-1399
    • Zhou, J.1    Kim, S.R.2    Westlund, B.S.3    Sparrow, J.R.4
  • 53
    • 33750814597 scopus 로고    scopus 로고
    • Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
    • Zhou J, Jang YP, Kim SR, Sparrow JR. Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium. Proc Natl Acad Sci U S A 2006; 103(44): 16182-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.44 , pp. 16182-16187
    • Zhou, J.1    Jang, Y.P.2    Kim, S.R.3    Sparrow, J.R.4
  • 54
    • 33947160639 scopus 로고    scopus 로고
    • Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments
    • Chen M, Forrester JV, Xu H. Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments. Exp Eye Res 2007; 84(4): 635-45.
    • (2007) Exp Eye Res , vol.84 , Issue.4 , pp. 635-645
    • Chen, M.1    Forrester, J.V.2    Xu, H.3
  • 55
    • 65549154386 scopus 로고    scopus 로고
    • The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration
    • Javitt NB, Javitt JC. The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration. Curr Opin Ophthalmol 2009; 20(3): 151-7.
    • (2009) Curr Opin Ophthalmol , vol.20 , Issue.3 , pp. 151-157
    • Javitt, N.B.1    Javitt, J.C.2
  • 56
    • 67650547973 scopus 로고    scopus 로고
    • Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury
    • [Thurman JM, Renner B, Kunchithapautham K, et al. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. J Biol Chem 2009; 284(25):16939-47.
    • (2009) J Biol Chem , vol.284 , Issue.25 , pp. 16939-16947
    • Thurman, J.M.1    Renner, B.2    Kunchithapautham, K.3
  • 57
    • 34547963062 scopus 로고    scopus 로고
    • Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXP3
    • Wu Z, Lauer TW, Sick A, Hackett SF, Campochiaro PA. Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXP3. J Biol Chem 2007; 282(31): 22414-25.
    • (2007) J Biol Chem , vol.282 , Issue.31 , pp. 22414-22425
    • Wu, Z.1    Lauer, T.W.2    Sick, A.3    Hackett, S.F.4    Campochiaro, P.A.5
  • 58
    • 65549129157 scopus 로고    scopus 로고
    • Prediction model for prevalence and incidence of advanced agerelated macular degeneration based on genetic, demographic, and environmental variables
    • Seddon JM, Reynolds R, Maller J, Fagerness JA, Daly MJ, Rosner B. Prediction model for prevalence and incidence of advanced agerelated macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci 2009; 50(5): 2044-53.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.5 , pp. 2044-2053
    • Seddon, J.M.1    Reynolds, R.2    Maller, J.3    Fagerness, J.A.4    Daly, M.J.5    Rosner, B.6
  • 59
    • 65549091490 scopus 로고    scopus 로고
    • The Y402H variant of complement factor H is associated with agerelated macular degeneration but not with diabetic retinal disease in the Go-DARTS study
    • Doney AS, Leese GP, Olson J, Morris AD, Palmer CN. The Y402H variant of complement factor H is associated with agerelated macular degeneration but not with diabetic retinal disease in the Go-DARTS study. Diabet Med 2009; 26(5): 460-5.
    • (2009) Diabet Med , vol.26 , Issue.5 , pp. 460-465
    • Doney, A.S.1    Leese, G.P.2    Olson, J.3    Morris, A.D.4    Palmer, C.N.5
  • 60
    • 34848819435 scopus 로고    scopus 로고
    • Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration
    • Lommatzsch A, Hermans P, Weber B, Pauleikhoff D. Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2007; 245(11): 1713-6.
    • (2007) Graefes Arch Clin Exp Ophthalmol , vol.245 , Issue.11 , pp. 1713-1716
    • Lommatzsch, A.1    Hermans, P.2    Weber, B.3    Pauleikhoff, D.4
  • 61
    • 33645419787 scopus 로고    scopus 로고
    • Variation in factor B (BF) and complement component 2 (C2) genes is associated with agerelated macular degeneration
    • Gold B, Merriam JE, Zernant J, et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with agerelated macular degeneration. Nat Genet 2006; 38(4): 458-62.
    • (2006) Nat Genet , vol.38 , Issue.4 , pp. 458-462
    • Gold, B.1    Merriam, J.E.2    Zernant, J.3
  • 62
    • 33748309136 scopus 로고    scopus 로고
    • Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
    • Maller J, George S, Purcell S, et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet 2006; 38(9):1055-9.
    • (2006) Nat Genet , vol.38 , Issue.9 , pp. 1055-1059
    • Maller, J.1    George, S.2    Purcell, S.3
  • 63
    • 34748819371 scopus 로고    scopus 로고
    • Variation in complement factor 3 is associated with risk of age-related macular degeneration
    • Maller JB, Fagerness JA, Reynolds RC, Neale BM, Daly MJ, Seddon JM. Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 2007; 39(10): 1200-1.
    • (2007) Nat Genet , vol.39 , Issue.10 , pp. 1200-1201
    • Maller, J.B.1    Fagerness, J.A.2    Reynolds, R.C.3    Neale, B.M.4    Daly, M.J.5    Seddon, J.M.6
  • 65
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 2005; 102(20): 7227-32.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.20 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3
  • 67
    • 57649230772 scopus 로고    scopus 로고
    • The complement fitness factor H: Role in human diseases and for immune escape of pathogens, like pneumococci
    • Zipfel PF, Hallström T, Hammerschmidt S, Skerka C. The complement fitness factor H: role in human diseases and for immune escape of pathogens, like pneumococci. Vaccine 2008; 26 (Suppl 8): I67-74.
    • (2008) Vaccine , vol.26 , Issue.SUPPL. 8 , pp. 67-74
    • Zipfel, P.F.1    Hallström, T.2    Hammerschmidt, S.3    Skerka, C.4
  • 69
    • 67650519801 scopus 로고    scopus 로고
    • Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers
    • Clinical Genomic And Proteomic Study Group
    • Gu J, Paeur GJ, Yue X, et al. Clinical Genomic And Proteomic Study Group. Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers. Mol Cell Proteomics 2009; 8(6): 1338-49.
    • (2009) Mol Cell Proteomics , vol.8 , Issue.6 , pp. 1338-1349
    • Gu, J.1    Paeur, G.J.2    Yue, X.3
  • 70
    • 34247573496 scopus 로고    scopus 로고
    • Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration
    • Skerka C, Lauer N, Weinberger AA, et al. Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration. Mol Immunol 2007; 44(13):3398-406.
    • (2007) Mol Immunol , vol.44 , Issue.13 , pp. 3398-3406
    • Skerka, C.1    Lauer, N.2    Weinberger, A.A.3
  • 71
    • 33746190776 scopus 로고    scopus 로고
    • Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: Role of factor B and factor H
    • Bora NS, Kaliappan S, Jha P, et al. Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H. J Immunol 2006; 177(3):1872-8.
    • (2006) J Immunol , vol.177 , Issue.3 , pp. 1872-1878
    • Bora, N.S.1    Kaliappan, S.2    Jha, P.3
  • 72
    • 2442580225 scopus 로고    scopus 로고
    • Genetic and environmental factors influencing the human factor H plasma levels
    • Esparza-Gordillo J, Soria JM, Buil A, et al. Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics 2004; 56(2): 77-82.
    • (2004) Immunogenetics , vol.56 , Issue.2 , pp. 77-82
    • Esparza-Gordillo, J.1    Soria, J.M.2    Buil, A.3
  • 73
    • 0021928942 scopus 로고
    • Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complement
    • Kew RR, Ghebrehiwet B, Janoff A. Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complement. J Clin Invest 1985; 75(3): 1000-7.
    • (1985) J Clin Invest , vol.75 , Issue.3 , pp. 1000-1007
    • Kew, R.R.1    Ghebrehiwet, B.2    Janoff, A.3
  • 74
    • 34447323841 scopus 로고    scopus 로고
    • Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver
    • Bykov I, Junnikkala S, Pekna M, Lindros KO, Meri S. Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver. Clin Immunol 2007; 124(2): 213-20.
    • (2007) Clin Immunol , vol.124 , Issue.2 , pp. 213-220
    • Bykov, I.1    Junnikkala, S.2    Pekna, M.3    Lindros, K.O.4    Meri, S.5
  • 75
    • 53049092112 scopus 로고    scopus 로고
    • Alcohol and nicotine consumption exacerbates choroidal neovascularization by modulating the regulation of complement system
    • Kaliappan S, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS. Alcohol and nicotine consumption exacerbates choroidal neovascularization by modulating the regulation of complement system. FEBS Lett 2008; 582(23-24): 3451-8.
    • (2008) FEBS Lett , vol.582 , Issue.23-24 , pp. 3451-3458
    • Kaliappan, S.1    Jha, P.2    Lyzogubov, V.V.3    Tytarenko, R.G.4    Bora, N.S.5    Bora, P.S.6
  • 76
    • 33745136772 scopus 로고    scopus 로고
    • Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization
    • Bora PS, Kaliappan S, Xu Q, et al. Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization. FEBS J 2006; 273(7): 1403-14.
    • (2006) FEBS J , vol.273 , Issue.7 , pp. 1403-1414
    • Bora, P.S.1    Kaliappan, S.2    Xu, Q.3
  • 77
    • 40049084357 scopus 로고    scopus 로고
    • Risk factors for primary open angle glaucoma progression: What we know and what we need to know
    • Rivera JL, Bell NP, Feldman RM. Risk factors for primary open angle glaucoma progression: what we know and what we need to know. Curr Opin Ophthalmol 2008; 19(2): 102-106.
    • (2008) Curr Opin Ophthalmol , vol.19 , Issue.2 , pp. 102-106
    • Rivera, J.L.1    Bell, N.P.2    Feldman, R.M.3
  • 78
    • 34248144933 scopus 로고    scopus 로고
    • From ocular hypertension to ganglion cell death: A theoretical sequence of events leading to glaucoma
    • Nickells RW. From ocular hypertension to ganglion cell death: a theoretical sequence of events leading to glaucoma. Can J Ophthalmol 2007; 42(2): 278-87.
    • (2007) Can J Ophthalmol , vol.42 , Issue.2 , pp. 278-287
    • Nickells, R.W.1
  • 79
    • 42449130879 scopus 로고    scopus 로고
    • Immunological mechanisms in glaucoma
    • Grus F, Sun D. Immunological mechanisms in glaucoma. Semin Immunopathol 2008; 30(2): 121-126.
    • (2008) Semin Immunopathol , vol.30 , Issue.2 , pp. 121-126
    • Grus, F.1    Sun, D.2
  • 82
    • 2142810973 scopus 로고    scopus 로고
    • Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure
    • Ahmed F, Brown KM, Stephan DA, Morrison JC, Johnson EC, Tomarev SI. Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure. Invest Ophthalmol Vis Sci 2004; 45(4): 1247-58.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.4 , pp. 1247-1258
    • Ahmed, F.1    Brown, K.M.2    Stephan, D.A.3    Morrison, J.C.4    Johnson, E.C.5    Tomarev, S.I.6
  • 83
    • 33645402376 scopus 로고    scopus 로고
    • Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes
    • [Stasi K, Nagel D, Yang X, et al. Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes. Invest Ophthalmol Vis Sci 2006; 47(3): 1024-9.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.3 , pp. 1024-1029
    • Stasi, K.1    Nagel, D.2    Yang, X.3
  • 84
    • 33745121143 scopus 로고    scopus 로고
    • Retinal synthesis and deposition of complement components induced by ocular hypertension
    • Kuehn MH, Kim CY, Ostojic J, et al. Retinal synthesis and deposition of complement components induced by ocular hypertension. Exp Eye Res 2006; 83(3): 620-8.
    • (2006) Exp Eye Res , vol.83 , Issue.3 , pp. 620-628
    • Kuehn, M.H.1    Kim, C.Y.2    Ostojic, J.3
  • 85
    • 48749128086 scopus 로고    scopus 로고
    • Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion
    • Kuehn MH, Kim CY, Jiang B, Dumitrescu AV, Kwon YH. Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Exp Eye Res 2008; 87(2): 89-95.
    • (2008) Exp Eye Res , vol.87 , Issue.2 , pp. 89-95
    • Kuehn, M.H.1    Kim, C.Y.2    Jiang, B.3    Dumitrescu, A.V.4    Kwon, Y.H.5
  • 87
    • 0034495294 scopus 로고    scopus 로고
    • Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis
    • Singhrao SK, Neal JW, Rushmere NK, Morgan BP, Gasque P. Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis. Am J Pathol 2000; 157(3): 905-18.
    • (2000) Am J Pathol , vol.157 , Issue.3 , pp. 905-918
    • Singhrao, S.K.1    Neal, J.W.2    Rushmere, N.K.3    Morgan, B.P.4    Gasque, P.5
  • 88
    • 68049085460 scopus 로고    scopus 로고
    • Association of diabetes with age-related macular degeneration in the EUREYE study
    • Topouzis F, Anastasopoulos E, Augood C, et al. Association of diabetes with age-related macular degeneration in the EUREYE study. Br J Ophthalmol 2009; 93(8): 1037-41.
    • (2009) Br J Ophthalmol , vol.93 , Issue.8 , pp. 1037-1041
    • Topouzis, F.1    Anastasopoulos, E.2    Augood, C.3
  • 89
    • 0036210286 scopus 로고    scopus 로고
    • Extensive deposits of complement C3d and C5b-9 in the choriocapillaris of eyes of patients with diabetic retinopathy
    • Gerl VB, Bohl J, Pitz S, Stoffelns B, Pfeiffer N, Bhakdi S. Extensive deposits of complement C3d and C5b-9 in the choriocapillaris of eyes of patients with diabetic retinopathy. Invest Ophthalmol Vis Sci 2002; 43(4): 1104-8.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.4 , pp. 1104-1108
    • Gerl, V.B.1    Bohl, J.2    Pitz, S.3    Stoffelns, B.4    Pfeiffer, N.5    Bhakdi, S.6
  • 90
    • 0036894348 scopus 로고    scopus 로고
    • Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy
    • Zhang J, Gerhardinger C, Lorenzi M. Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy. Diabetes 2002; 51(12): 3499-504.
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3499-3504
    • Zhang, J.1    Gerhardinger, C.2    Lorenzi, M.3
  • 92
    • 3242755116 scopus 로고    scopus 로고
    • Are phospholipid-binding antibodies implicated in the pathogenesis of diabetic microangiopathy?
    • Giusti C. Are phospholipid-binding antibodies implicated in the pathogenesis of diabetic microangiopathy? Med Hypotheses 2004; 63(2): 235-8.
    • (2004) Med Hypotheses , vol.63 , Issue.2 , pp. 235-238
    • Giusti, C.1
  • 93
    • 4344658774 scopus 로고    scopus 로고
    • Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy
    • Dagher Z, Park YS, Asnaghi V, Hoehn T, Gerhardinger C, Lorenzi M. Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy. Diabetes 2004; 53(9): 2404-11.
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2404-2411
    • Dagher, Z.1    Park, Y.S.2    Asnaghi, V.3    Hoehn, T.4    Gerhardinger, C.5    Lorenzi, M.6
  • 94
    • 33750869527 scopus 로고    scopus 로고
    • A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy
    • Sun W, Oates PJ, Coutcher JB, Gerhardinger C, Lorenzi M. A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy. Diabetes 2006; 55(10): 2757-62.
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2757-2762
    • Sun, W.1    Oates, P.J.2    Coutcher, J.B.3    Gerhardinger, C.4    Lorenzi, M.5
  • 95
    • 0021850016 scopus 로고
    • Diabetic choroidopathy Light and electron microscopic observations of seven cases
    • Hidayat AA, Fine BS. Diabetic choroidopathy. Light and electron microscopic observations of seven cases. Ophthalmology 1985; 92(4): 512-22.
    • (1985) Ophthalmology , vol.92 , Issue.4 , pp. 512-522
    • Hidayat, A.A.1    Fine, B.S.2
  • 96
    • 0024789889 scopus 로고
    • Diabetic choroidal and iris vasculature scanning electron microscopy findings
    • Fryczkowski AW, Hodes BL, Walker J. Diabetic choroidal and iris vasculature scanning electron microscopy findings. Int Ophthalmol 1989; 13(4): 269-79.
    • (1989) Int Ophthalmol , vol.13 , Issue.4 , pp. 269-279
    • Fryczkowski, A.W.1    Hodes, B.L.2    Walker, J.3
  • 97
    • 0031696332 scopus 로고    scopus 로고
    • Choriocapillaris degeneration and related pathologic changes in human diabetic eyes
    • Cao J, McLeod S, Merges CA, Lutty GA. Choriocapillaris degeneration and related pathologic changes in human diabetic eyes. Arch Ophthalmol 1998; 116(5): 589-97.
    • (1998) Arch Ophthalmol , vol.116 , Issue.5 , pp. 589-597
    • Cao, J.1    McLeod, S.2    Merges, C.A.3    Lutty, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.