메뉴 건너뛰기




Volumn 53, Issue 9, 2004, Pages 2404-2411

Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; COMPLEMENT INHIBITOR; GALACTOSE; GLUCOSE; POLYOL; SORBITOL;

EID: 4344658774     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.9.2404     Document Type: Article
Times cited : (190)

References (49)
  • 1
    • 0034933340 scopus 로고    scopus 로고
    • Early cellular and molecular changes induced by diabetes in the retina
    • Lorenzi M, Gerhardinger C: Early cellular and molecular changes induced by diabetes in the retina. Diabetologia 44:791-804, 2001
    • (2001) Diabetologia , vol.44 , pp. 791-804
    • Lorenzi, M.1    Gerhardinger, C.2
  • 2
    • 0024528919 scopus 로고
    • Diabetic retinopathy
    • Kohner EM: Diabetic retinopathy. Br Med Bull 45:148-173, 1989
    • (1989) Br Med Bull , vol.45 , pp. 148-173
    • Kohner, E.M.1
  • 3
    • 0015929739 scopus 로고
    • The sorbitol pathway and the complications of diabetes
    • Gabbay KH: The sorbitol pathway and the complications of diabetes. N Engl J Med 288:831-836, 1973
    • (1973) N Engl J Med , vol.288 , pp. 831-836
    • Gabbay, K.H.1
  • 5
    • 0032725789 scopus 로고    scopus 로고
    • Interaction between osmotic and oxidative stress in diabetic precataractous lens: Studies with a sorbitol dehydrogenase inhibitor
    • Obrosova IG, Fathallah L, Lang HJ: Interaction between osmotic and oxidative stress in diabetic precataractous lens: studies with a sorbitol dehydrogenase inhibitor. Biochem Pharmacol 58:1945-1954, 1999
    • (1999) Biochem Pharmacol , vol.58 , pp. 1945-1954
    • Obrosova, I.G.1    Fathallah, L.2    Lang, H.J.3
  • 7
    • 4344562354 scopus 로고    scopus 로고
    • Genetics of aldose reductase and susceptibility to diabetic retinopathy
    • Demaine AG, Cross DF: Genetics of aldose reductase and susceptibility to diabetic retinopathy. Appl Genomics Proteomics 1:1-13, 2002
    • (2002) Appl Genomics Proteomics , vol.1 , pp. 1-13
    • Demaine, A.G.1    Cross, D.F.2
  • 9
    • 0025140713 scopus 로고
    • Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors
    • Kador PF, Akagi Y, Takahashi Y, Ikebe H, Wyman M, Kinoshita JH: Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors. Arch Ophthalmol 108:1301-1309, 1990
    • (1990) Arch Ophthalmol , vol.108 , pp. 1301-1309
    • Kador, P.F.1    Akagi, Y.2    Takahashi, Y.3    Ikebe, H.4    Wyman, M.5    Kinoshita, J.H.6
  • 10
    • 0027271798 scopus 로고
    • Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs
    • Engerman RL, Kern TS: Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs. Diabetes 42:820-825, 1993
    • (1993) Diabetes , vol.42 , pp. 820-825
    • Engerman, R.L.1    Kern, T.S.2
  • 11
    • 0025073693 scopus 로고
    • A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy
    • Sorbinil Retinopathy Trial Research Group: A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy. Arch Ophthalmol 108:1234-1244, 1990
    • (1990) Arch Ophthalmol , vol.108 , pp. 1234-1244
  • 12
    • 0037317423 scopus 로고    scopus 로고
    • A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat
    • Asnaghi V, Gerhardinger C, Hoehn T, Adeboje A, Lorenzi M: A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat. Diabetes 52:506-511, 2003
    • (2003) Diabetes , vol.52 , pp. 506-511
    • Asnaghi, V.1    Gerhardinger, C.2    Hoehn, T.3    Adeboje, A.4    Lorenzi, M.5
  • 13
    • 0019250369 scopus 로고
    • Immunohistochemical localization of aldose reductase. II. Rat eye and kidney
    • Ludvigson MA, Sorenson RI: Immunohistochemical localization of aldose reductase. II. Rat eye and kidney. Diabetes 29:450-459, 1980
    • (1980) Diabetes , vol.29 , pp. 450-459
    • Ludvigson, M.A.1    Sorenson, R.I.2
  • 14
    • 0023204429 scopus 로고
    • Aldose reductase in the BB rat: Isolation, immunological identification and localization in the retina and peripheral nerve
    • Chakrabarti S, Sima AAF, Nakajima T, Yagihashi S, Greene DA: Aldose reductase in the BB rat: isolation, immunological identification and localization in the retina and peripheral nerve. Diabetologia 30:244-251, 1987
    • (1987) Diabetologia , vol.30 , pp. 244-251
    • Chakrabarti, S.1    Sima, A.A.F.2    Nakajima, T.3    Yagihashi, S.4    Greene, D.A.5
  • 15
    • 0019501225 scopus 로고
    • Distribution of aldose reductase in ocular tissues
    • Kern TS, Engerman RL: Distribution of aldose reductase in ocular tissues. Exp Eye Res 33:175-182, 1981
    • (1981) Exp Eye Res , vol.33 , pp. 175-182
    • Kern, T.S.1    Engerman, R.L.2
  • 17
    • 0033624560 scopus 로고    scopus 로고
    • Control of Müller glial cell proliferation and activation following retinal injury
    • Dyer MA, Cepko CL: Control of Müller glial cell proliferation and activation following retinal injury. Nat Neurosci 3:873-880, 2000
    • (2000) Nat Neurosci , vol.3 , pp. 873-880
    • Dyer, M.A.1    Cepko, C.L.2
  • 19
    • 0036894348 scopus 로고    scopus 로고
    • Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy
    • Zhang J, Gerhardinger C, Lorenzi M: Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy. Diabetes 51:3499-3504, 2002
    • (2002) Diabetes , vol.51 , pp. 3499-3504
    • Zhang, J.1    Gerhardinger, C.2    Lorenzi, M.3
  • 20
    • 0029973474 scopus 로고    scopus 로고
    • Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy
    • Mizutani M, Kern TS, Lorenzi M: Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest 97:2883-2890, 1996
    • (1996) J Clin Invest , vol.97 , pp. 2883-2890
    • Mizutani, M.1    Kern, T.S.2    Lorenzi, M.3
  • 21
    • 33750809382 scopus 로고
    • Retinal vascular patterns. IV. Diabetic retinopathy
    • Cogan DG, Toussaint D, Kuwabara T: Retinal vascular patterns. IV. Diabetic retinopathy. Arch Ophthalmol 613:366-378, 1961
    • (1961) Arch Ophthalmol , vol.613 , pp. 366-378
    • Cogan, D.G.1    Toussaint, D.2    Kuwabara, T.3
  • 22
    • 0014748128 scopus 로고
    • Correlation of fluorescein angiogram and retinal digest in diabetic retinopathy
    • Kohner EM, Henkind P: Correlation of fluorescein angiogram and retinal digest in diabetic retinopathy. Am J Ophthalmol 69:403-414, 1970
    • (1970) Am J Ophthalmol , vol.69 , pp. 403-414
    • Kohner, E.M.1    Henkind, P.2
  • 23
    • 0028577909 scopus 로고
    • Comparison of retinal lesions in alloxan-diabetic rats and galactose-fed rats
    • Kern TS, Engerman RL: Comparison of retinal lesions in alloxan-diabetic rats and galactose-fed rats. Curr Eye Res 13:863-867, 1994
    • (1994) Curr Eye Res , vol.13 , pp. 863-867
    • Kern, T.S.1    Engerman, R.L.2
  • 25
    • 0033902815 scopus 로고    scopus 로고
    • Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro
    • Podestá F, Romeo G, Liu W-H, Krajewski S, Reed JC, Gerhardinger C, Lorenzi M: Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro. Am J Pathol 156:1025-1032, 2000
    • (2000) Am J Pathol , vol.156 , pp. 1025-1032
    • Podestá, F.1    Romeo, G.2    Liu, W.-H.3    Krajewski, S.4    Reed, J.C.5    Gerhardinger, C.6    Lorenzi, M.7
  • 26
    • 0037646838 scopus 로고    scopus 로고
    • Isolation and characterization of murine retinal endothelial cells
    • Su X, Sorenson CM, Sheibani N: Isolation and characterization of murine retinal endothelial cells. Molec Vision 9:171-178, 2003
    • (2003) Molec Vision , vol.9 , pp. 171-178
    • Su, X.1    Sorenson, C.M.2    Sheibani, N.3
  • 28
    • 0032972617 scopus 로고    scopus 로고
    • Tissue distribution of the rat analogue of decay-accelerating factor
    • Spiller OB, Hanna SM, Morgan BP: Tissue distribution of the rat analogue of decay-accelerating factor. Immunology 97:374-384, 1999
    • (1999) Immunology , vol.97 , pp. 374-384
    • Spiller, O.B.1    Hanna, S.M.2    Morgan, B.P.3
  • 30
    • 0019271436 scopus 로고
    • Red cell sorbitol: An indicator of diabetic control
    • Malone JI, Knox G, Benford S, Tedesco TA: Red cell sorbitol: an indicator of diabetic control. Diabetes 29:861-864, 1980
    • (1980) Diabetes , vol.29 , pp. 861-864
    • Malone, J.I.1    Knox, G.2    Benford, S.3    Tedesco, T.A.4
  • 31
    • 0021807568 scopus 로고
    • A morphologic and autoradiographic study of cell death and regeneration in the retinal microvasculature of normal and diabetic rats
    • Sharma NK, Gardiner TA, Archer DB: A morphologic and autoradiographic study of cell death and regeneration in the retinal microvasculature of normal and diabetic rats. Am J Ophthalmol 100:51-60, 1985
    • (1985) Am J Ophthalmol , vol.100 , pp. 51-60
    • Sharma, N.K.1    Gardiner, T.A.2    Archer, D.B.3
  • 32
    • 0031025201 scopus 로고    scopus 로고
    • The biology of PECAM-1
    • Newman PJ: The biology of PECAM-1. J Clin Invest 99:3-8, 1997
    • (1997) J Clin Invest , vol.99 , pp. 3-8
    • Newman, P.J.1
  • 33
    • 0022359247 scopus 로고
    • Activation of aldose reductase from human tissues
    • Das B, Srivastava SK: Activation of aldose reductase from human tissues. Diabetes 34:1145-1151, 1985
    • (1985) Diabetes , vol.34 , pp. 1145-1151
    • Das, B.1    Srivastava, S.K.2
  • 36
    • 0035434119 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy
    • Kowluru RA, Tang J, Kern TS: Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy. Diabetes 50:1938-1942, 2001
    • (2001) Diabetes , vol.50 , pp. 1938-1942
    • Kowluru, R.A.1    Tang, J.2    Kern, T.S.3
  • 37
    • 0030802526 scopus 로고    scopus 로고
    • Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine
    • Hammes HP, Bartmann A, Engel L, Wülfroth P: Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine. Diabetologia 40:629-634, 1997
    • (1997) Diabetologia , vol.40 , pp. 629-634
    • Hammes, H.P.1    Bartmann, A.2    Engel, L.3    Wülfroth, P.4
  • 39
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
    • Baynes JW, Thorpe SR: Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 48:1-9, 1999
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 40
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • Koya D, King GL: Protein kinase C activation and the development of diabetic complications. Diabetes 47:859-866, 1998
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 41
    • 0032947546 scopus 로고    scopus 로고
    • Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis
    • Rittner HL, Hafner V, Klimiuk PA, Szweda LI, Goronzy JJ, Weyand CM: Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. J Clin Invest 103:1007-1013, 1999
    • (1999) J Clin Invest , vol.103 , pp. 1007-1013
    • Rittner, H.L.1    Hafner, V.2    Klimiuk, P.A.3    Szweda, L.I.4    Goronzy, J.J.5    Weyand, C.M.6
  • 42
    • 0344837811 scopus 로고    scopus 로고
    • Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats
    • Obrosova IG, Minchenko AG, Vasupuram R, White L, Abatan OI, Kumagai AK, Frank RN, Stevens MJ: Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats. Diabetes 52:864-871, 2003
    • (2003) Diabetes , vol.52 , pp. 864-871
    • Obrosova, I.G.1    Minchenko, A.G.2    Vasupuram, R.3    White, L.4    Abatan, O.I.5    Kumagai, A.K.6    Frank, R.N.7    Stevens, M.J.8
  • 43
    • 0027144407 scopus 로고
    • Human kidney aldose and aldehyde reductases
    • Sato S, Kador PF: Human kidney aldose and aldehyde reductases. J Diabetes Complications 7:179-187, 1993
    • (1993) J Diabetes Complications , vol.7 , pp. 179-187
    • Sato, S.1    Kador, P.F.2
  • 44
    • 0348056314 scopus 로고    scopus 로고
    • Aldose reductase and vascular stress
    • Marso SP, Stern DM, Eds. Philadelphia, Lippincott, Williams & Wilkins
    • Ramasamy R, Oates PJ: Aldose reductase and vascular stress. In Diabetes and Cardiovascular Disease. Marso SP, Stern DM, Eds. Philadelphia, Lippincott, Williams & Wilkins, 2004, p. 55-74
    • (2004) Diabetes and Cardiovascular Disease , pp. 55-74
    • Ramasamy, R.1    Oates, P.J.2
  • 45
    • 0036306098 scopus 로고    scopus 로고
    • Activation of nuclear factor-κB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes
    • Romeo G, Liu W-H, Asnaghi V, Kern TS, Lorenzi M: Activation of nuclear factor-κB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes. Diabetes 51:2241-2248, 2002
    • (2002) Diabetes , vol.51 , pp. 2241-2248
    • Romeo, G.1    Liu, W.-H.2    Asnaghi, V.3    Kern, T.S.4    Lorenzi, M.5
  • 46
    • 0030048984 scopus 로고    scopus 로고
    • Exogenous insulin administration and cardiovascular risk in non-insulin-dependent and insulin-dependent diabetes mellitus
    • Genuth S: Exogenous insulin administration and cardiovascular risk in non-insulin-dependent and insulin-dependent diabetes mellitus. Ann Intern Med 124:104-109, 1996
    • (1996) Ann Intern Med , vol.124 , pp. 104-109
    • Genuth, S.1
  • 47
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
    • Stratton IM, Adler AI, Neil HAW, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holman RR, UK Prospective Diabetes Study Group: Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. Br Med J 321:405-412, 2000
    • (2000) Br Med J , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.W.3    Matthews, D.R.4    Manley, S.E.5    Cull, C.A.6    Hadden, D.7    Turner, R.C.8    Holman, R.R.9
  • 48
    • 0037986208 scopus 로고    scopus 로고
    • Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus
    • The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group: Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus N Engl J Med 348:2294-2303, 2000
    • (2000) N Engl J Med , vol.348 , pp. 2294-2303


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.