Enhanced stability and knockdown efficiency of poly(ethylene glycol)-b-polyphosphoramidate/siRNA micellar nanoparticles by Co-condensation with sodium triphosphate

Pharmaceutical Research

Volumn 28, Issue 7, 2011, Pages 1723-1732

  Nakanishi, Masataka ^a,b   Patil, Rajesh ^a   Ren, Yong ^a   Shyam, Rishab ^c   Wong, Philip ^d   Mao, Hai Quan ^a,b,c,e  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NONE   (United States)

Author keywords

block copolymer gene carrier; siRNA; sodium triphosphate; stabilization; ternary nanoparticles

Indexed keywords

COPOLYMER; MACROGOL PHOSPHORAMIDIC ACID COPOLYMER; NANOPARTICLE; SMALL INTERFERING RNA; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; GEL ELECTROPHORESIS; GENE SILENCING; HUMAN; HUMAN CELL; IONIC STRENGTH; LIGHT SCATTERING; MICELLE; MOLECULAR STABILITY; POLYMERIZATION; PRIORITY JOURNAL;

AMIDES; ANIONS; CELL SURVIVAL; DRUG STABILITY; GENE SILENCING; HELA CELLS; HUMANS; MICELLES; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; PHOSPHORIC ACIDS; POLYETHYLENE GLYCOLS; POLYPHOSPHATES; RNA, SMALL INTERFERING;

EID: 79959911896     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0408-7     Document Type: Article

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