Cationic siRNAs provide carrier-free gene silencing in animal cells

Journal of the American Chemical Society

Volumn 131, Issue 49, 2009, Pages 17730-17731

  Nothisen, Marc ^a   Kotera, Mitsuharu ^a   Voirin, Emilie ^b   Remy, Jean Serge ^a   Behr, Jean Paul ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Bioparc   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELLS; CARRIER-LESS; CHARGE RATIO; EXTRACELLULAR; GENE SILENCING; INTRACELLULAR DELIVERY; LUCIFERASE GENES; MOLECULAR APPROACH; OLIGONUCLEOTIDE CONJUGATES; PHOSPHORAMIDITES; SELECTIVE INHIBITION; SUBMICROMOLAR CONCENTRATIONS; SUPRAMOLECULAR COMPLEXES;

CYTOLOGY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ENGINEERING; NUCLEIC ACIDS; OLIGONUCLEOTIDES; SYNTHESIS (CHEMICAL);

DYES;

NANOPARTICLE; PROTEOHEPARAN SULFATE; RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHEMICAL STRUCTURE; CYTOPLASM; ENDOCYTOSIS; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN;

CATIONS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE SILENCING; HELA CELLS; HUMANS; LUCIFERASES; OLIGODEOXYRIBONUCLEOTIDES; RNA, SMALL INTERFERING; SPERMINE;

EID: 71749111525     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja908017e     Document Type: Article

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