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Volumn 10, Issue 2, 2010, Pages 139-155

siRNA delivery using nanocarriers - An efficient tool for gene silencing

Author keywords

Gene silencing; Non viral vector; Polymeric systems; siRNA; Viral vector

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ADENOVIRUS VECTOR; ALGINIC ACID; CARDIOLIPIN; CHITOSAN; LENTIVIRUS VECTOR; LIPOPLEX; LIPOSOME; NANOCARRIER; NANOPARTICLE; RETROVIRUS VECTOR; SMALL INTERFERING RNA; VIRUS VECTOR;

EID: 77950929285     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652310791111010     Document Type: Review
Times cited : (35)

References (203)
  • 1
    • 0034328925 scopus 로고    scopus 로고
    • Gene Therapy: Trials and tribulation
    • Somia N, Verma IM. Gene Therapy: trials and tribulation. Nat Rev Genet 2000; 1: 91-99.
    • (2000) Nat Rev Genet , vol.1 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 2
    • 33645747583 scopus 로고    scopus 로고
    • RNA based gene therapy for dominantly inherited diseases
    • Pelletier R, Caron SOP, Puymirat J. RNA based gene therapy for dominantly inherited diseases. Curr Gene Ther 2006; 6: 131-146.
    • (2006) Curr Gene Ther , vol.6 , pp. 131-146
    • Pelletier, R.1    Caron, S.O.P.2    Puymirat, J.3
  • 5
    • 77950956498 scopus 로고    scopus 로고
    • RNA Interference in mammalian cell systems
    • Paddison PJ, Vogt PK, Eds., Springer-Verlag Berlin Heidelberg
    • Paddison PJ. RNA Interference in mammalian cell systems, In: Paddison PJ, Vogt PK, Eds., RNA interference. Springer-Verlag Berlin Heidelberg, 2008; pp. 1-20.
    • (2008) RNA Interference , pp. 1-20
    • Paddison, P.J.1
  • 6
    • 30344454402 scopus 로고    scopus 로고
    • Short interfering RNA (siRNA): Tool or therapeutic?
    • DOI 10.1042/CS20050162
    • Cejka D, Losert D, Wacheck V. Short interfering RNA (siRNA): tool or therapeutic Clinical. Science 2006; 110: 47-58. (Pubitemid 43059044)
    • (2006) Clinical Science , vol.110 , Issue.1 , pp. 47-58
    • Cejka, D.1    Losert, D.2    Wacheck, V.3
  • 7
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3: 737-747.
    • (2002) Nat Rev Genet , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 8
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 9
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • DOI 10.1093/emboj/20.23.6877
    • Elbashir SM, Martinez J, Patkaniowska A, et al. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001; 20: 6877-6888. (Pubitemid 33134217)
    • (2001) EMBO Journal , vol.20 , Issue.23 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 10
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21 and 22 nt RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21 and 22 nt RNAs. Genes Dev 2001; 15: 188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 11
    • 77950928723 scopus 로고    scopus 로고
    • Vector-based siRNA delivery strategies for high-throughput screening of novel target genes
    • Chen M, Du Q, Zhang HY, et al. Vector-based siRNA delivery strategies for high-throughput screening of novel target genes. J RNAi Gene Silencing 2005; 1: 5-11.
    • (2005) J RNAi Gene Silencing , vol.1 , pp. 5-11
    • Chen, M.1    Du, Q.2    Zhang, H.Y.3
  • 12
    • 21344457432 scopus 로고    scopus 로고
    • RNA interference: From gene silencing to gene-specific therapeutics
    • DOI 10.1016/j.pharmthera.2005.03.004, PII S0163725805000628
    • Leung PK, Whittaker PA. RNA interference: from gene silencing to gene-specific therapeutics. Pharmacol Ther 2005; 107: 222-239. (Pubitemid 40910042)
    • (2005) Pharmacology and Therapeutics , vol.107 , Issue.2 , pp. 222-239
    • Leung, R.K.M.1    Whittaker, P.A.2
  • 13
    • 33645165026 scopus 로고    scopus 로고
    • Viral-based modelling and correction of neurodegenerative diseases by RNA interference
    • Raoul C, Barker SD, Aebischer P. Viral-based modelling and correction of neurodegenerative diseases by RNA interference. Gene Ther 2006; 13: 487-495.
    • (2006) Gene Ther , vol.13 , pp. 487-495
    • Raoul, C.1    Barker, S.D.2    Aebischer, P.3
  • 14
    • 0037686295 scopus 로고    scopus 로고
    • Sharp, Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn DM, Novina CD, Sharp PA. Sharp, Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Bio 2003; 4; 457-467.
    • (2003) Nat Rev Mol Cell Bio , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 16
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNAinterference-based therapeutics
    • Castanotto D, Rossi JJ. The promises and pitfalls of RNAinterference- based therapeutics. Nature 2009; 457: 426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 19
    • 0038497542 scopus 로고
    • A Structure for deoxyribose nucleic acid
    • Watson JD, Crick FHC. A Structure for deoxyribose nucleic acid. Nature 1953; 171: 737-738.
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.C.2
  • 20
    • 0021229867 scopus 로고
    • Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis
    • Izant J., Weintraub H. Inhibition of thymidine kinase gene expression by antisense RNA: a molecular approach to genetic analysis. Cell 1984; 36: 1007-1015. (Pubitemid 14077960)
    • (1984) Cell , vol.36 , Issue.4 , pp. 1007-1015
    • Izant, J.G.1    Weintraub, H.2
  • 23
    • 3042659395 scopus 로고    scopus 로고
    • Small Interfering RNA: A new tool for gene therapy
    • Bi F, Liu N, Fan D. Small Interfering RNA: a new tool for gene therapy. Curr Gene Ther 2003; 3: 411-417.
    • (2003) Curr Gene Ther , vol.3 , pp. 411-417
    • Bi, F.1    Liu, N.2    Fan, D.3
  • 25
    • 26944441255 scopus 로고    scopus 로고
    • Dicing and slicing: The core machinery of the RNA interference pathway
    • Hammond SM. Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett 2005; 579: 5822-5829.
    • (2005) FEBS Lett , vol.579 , pp. 5822-5829
    • Hammond, S.M.1
  • 26
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • DOI 10.1101/gad.927801
    • Ketting RF, Fischer SEJ, Bernstein E, et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 2001; 15: 2654-2659. (Pubitemid 32988876)
    • (2001) Genes and Development , vol.15 , Issue.20 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.J.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.A.6
  • 27
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • DOI 10.1016/S0092-8674(01)00547-5
    • Nykanen A, Haley B, Zamore PD.ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 2001; 107: 309-321. (Pubitemid 33049975)
    • (2001) Cell , vol.107 , Issue.3 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 28
    • 28444437427 scopus 로고    scopus 로고
    • Slicer function of Drosophila Argonautes and its involvement in RISC formation
    • Miyoshi K, Tsukumo H, Nagami T, et al. Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes Dev 2005; 19: 2837-2848.
    • (2005) Genes Dev , vol.19 , pp. 2837-2848
    • Miyoshi, K.1    Tsukumo, H.2    Nagami, T.3
  • 29
    • 0036752785 scopus 로고    scopus 로고
    • RNAi in human cells: Basic structural and functional features of small interfering RNA
    • Chiu YL, Rana TM. RNAi in human cells: basic structural and functional features of small interfering RNA. Mol Cell 2002; 10: 549-561.
    • (2002) Mol Cell , vol.10 , pp. 549-561
    • Chiu, Y.L.1    Rana, T.M.2
  • 30
    • 3042602447 scopus 로고    scopus 로고
    • Kinetic analysis of the RNAi enzyme complex
    • DOI 10.1038/nsmb780
    • Haley B, Zamore PD. Kinetic analysis of the RNAi enzyme complex. Nature Struct Mol Biol 2004; 11: 599-606. (Pubitemid 38823525)
    • (2004) Nature Structural and Molecular Biology , vol.11 , Issue.7 , pp. 599-606
    • Haley, B.1    Zamore, P.D.2
  • 31
    • 32344448109 scopus 로고    scopus 로고
    • Argonaute and RNA-getting into the groove
    • Song JJ, Joshua-Tor L. Argonaute and RNA-getting into the groove. Curr Opin Struct Biol 2006; 16: 5-11
    • (2006) Curr Opin Struct Biol , vol.16 , pp. 5-11
    • Song, J.J.1    Joshua-Tor, L.2
  • 33
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double- Stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore PD, Tuschl T, Sharp PA, et al. RNAi: double- stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 2000; 101: 25-33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3
  • 34
    • 33644748110 scopus 로고    scopus 로고
    • Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila
    • DOI 10.1016/j.cub.2006.01.061, PII S0960982206011286
    • Preall JB, He Z, Gorra JM. Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila. Curr Biol 2006; 16: 530-535. (Pubitemid 43343716)
    • (2006) Current Biology , vol.16 , Issue.5 , pp. 530-535
    • Preall, J.B.1    He, Z.2    Gorra, J.M.3    Sontheimer, E.J.4
  • 35
    • 77950931731 scopus 로고    scopus 로고
    • RNA interference: From a research tool to a novel therapeutic agent
    • Vidugirieṅ J, Goueli S, Suziedelis K. RNA interference: from a research tool to a novel therapeutic agent. Acta Med Lituanica 2007; 14: 165-169.
    • (2007) Acta Med Lituanica , vol.14 , pp. 165-169
    • Vidugirien, J.1    Goueli, S.2    Suziedelis, K.3
  • 36
    • 0032410928 scopus 로고    scopus 로고
    • Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
    • Ngo H, Tschudi C, Gull K, Ullu E. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc Natl Acad Sci USA 1998; 95: 14687-14692.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14687-14692
    • Ngo, H.1    Tschudi, C.2    Gull, K.3    Ullu, E.4
  • 37
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzeled and frizzeled 2 act in the wingless pathway
    • Kennerdell JR, Carthew RW. Use of dsRNA-mediated genetic interference to demonstrate that frizzeled and frizzeled 2 act in the wingless pathway. Cell 1998; 95: 1017-1026.
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 38
    • 0033214763 scopus 로고    scopus 로고
    • Silencing of developmental genes in Hydra
    • Lohmann JU, Endl I, Bosch TC. Silencing of developmental genes in Hydra. Dev Biol 1999; 214: 211-214.
    • (1999) Dev Biol , vol.214 , pp. 211-214
    • Lohmann, J.U.1    Endl, I.2    Bosch, T.C.3
  • 39
  • 40
    • 0342626578 scopus 로고    scopus 로고
    • The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling
    • DOI 10.1038/35015500
    • Oelgeschlager M, Larrain J, Geissert D, et al. The evolutionarily conserved BMP-binding protein twisted gastrulation promotes BMP signalling. Nature 2000; 405: 757-763. (Pubitemid 30407840)
    • (2000) Nature , vol.405 , Issue.6788 , pp. 757-763
    • Oelgeschlager, M.1    Larrain, J.2    Geissert, D.3    De Robertis, E.M.4
  • 41
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F, Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat Cell Biol 2000; 2: 70-75.
    • (2000) Nat Cell Biol , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 42
    • 0029934123 scopus 로고    scopus 로고
    • Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
    • Cogni C, Irelan JT, Schumacher M, et al. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBO J 1996; 15: 3153-3163.
    • (1996) EMBO J , vol.15 , pp. 3153-3163
    • Cogni, C.1    Irelan, J.T.2    Schumacher, M.3
  • 43
    • 0032506226 scopus 로고    scopus 로고
    • Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
    • Waterhouse PM, Graham MW, Wang MB. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc Natl Acad Sci USA 1998; 95: 13959-13964.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13959-13964
    • Waterhouse, P.M.1    Graham, M.W.2    Wang, M.B.3
  • 44
    • 39549117983 scopus 로고    scopus 로고
    • Delivery vehicles for small interfering RNA in Vivo
    • De Fougerolles AR. Delivery vehicles for small interfering RNA In Vivo. Hum Gene Ther 2008; 19:125-132.
    • (2008) Hum Gene Ther , vol.19 , pp. 125-132
    • De Fougerolles, A.R.1
  • 45
    • 59849105155 scopus 로고    scopus 로고
    • Delivery of siRNA to the target cell cytoplasm: Photochemical internalization facilitates endosomal escape and improves silencing efficiency, in Vitro and in Vivo
    • Oliveira S, Hogset A, Storm G et al. Delivery of siRNA to the target cell cytoplasm: photochemical internalization facilitates endosomal escape and improves silencing efficiency, In Vitro and In Vivo. Curr Pharm Des 2008; 14: 3686-3697.
    • (2008) Curr Pharm Des , vol.14 , pp. 3686-3697
    • Oliveira, S.1    Hogset, A.2    Storm, G.3
  • 46
    • 32444445649 scopus 로고    scopus 로고
    • Harnessing in vivo siRNA delivery for drug discovery and therapeutic development
    • Xie FY, Woodle MC, Lu PY. Harnessing in vivo siRNA delivery for drug discovery and therapeutic development. Drug Discov Today 2006; 11: 67-73.
    • (2006) Drug Discov Today , vol.11 , pp. 67-73
    • Xie, F.Y.1    Woodle, M.C.2    Lu, P.Y.3
  • 47
  • 48
    • 54249143980 scopus 로고    scopus 로고
    • Barriers to successful delivery of short interfering RNA after systemic administration
    • White PJ. Barriers to successful delivery of short interfering RNA after systemic administration. Clin Exp Pharmacol Physiol 2008; 35: 1371-1376.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 1371-1376
    • White, P.J.1
  • 49
    • 34548818764 scopus 로고    scopus 로고
    • Cationic lipids and polymers mediated vectors for delivery of siRNA
    • DOI 10.1016/j.jconrel.2007.07.016, PII S0168365907003914
    • Zhang S, Zhao B, Jiang H, et al. Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 2007; 123: 1-10. (Pubitemid 47444388)
    • (2007) Journal of Controlled Release , vol.123 , Issue.1 , pp. 1-10
    • Zhang, S.1    Zhao, B.2    Jiang, H.3    Wang, B.4    Ma, B.5
  • 50
    • 8444226727 scopus 로고    scopus 로고
    • Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes
    • Lovett-Racke AE. Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes. Immunity 2004; 21: 719-731.
    • (2004) Immunity , vol.21 , pp. 719-731
    • Lovett-Racke, A.E.1
  • 51
    • 0042173218 scopus 로고    scopus 로고
    • siRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S. siRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res 2003; 63: 3919-3922.
    • (2003) Cancer Res , vol.63 , pp. 3919-3922
    • Filleur, S.1
  • 52
    • 10344228801 scopus 로고    scopus 로고
    • Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference
    • Thakker DR. Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference. Proc Natl Acad Sci USA 2004; 101:17270-17275.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17270-17275
    • Thakker, D.R.1
  • 53
    • 1242297011 scopus 로고    scopus 로고
    • Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization
    • DOI 10.1097/00006982-200402000-00018
    • Tolentino MJ. Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a non-human primate, laser-induced model of choroidal neovascularization. Retina 2004; 24:132-138. (Pubitemid 38240851)
    • (2004) Retina , vol.24 , Issue.1 , pp. 132-138
    • Tolentino, M.J.1    Brucker, A.J.2    Fosnot, J.3    Ying, G.-S.4    Wu, I.-H.5    Malik, G.6    Wan, S.7    Reich, S.J.8
  • 56
    • 28244480458 scopus 로고    scopus 로고
    • Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis
    • Perl M. Silencing of fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis. Am J Pathol 2005; 167: 1545-1559. (Pubitemid 41713309)
    • (2005) American Journal of Pathology , vol.167 , Issue.6 , pp. 1545-1559
    • Perl, M.1    Chung, C.-S.2    Lomas-Neira, J.3    Rachel, T.-M.4    Biffl, W.L.5    Cioffi, W.G.6    Ayala, A.7
  • 57
    • 10344261343 scopus 로고    scopus 로고
    • siRNA relieves chronic neuropathic pain
    • Dorn G. siRNA relieves chronic neuropathic pain. Nucleic Acids Res 2004; 32: e49.
    • (2004) Nucleic Acids Res , vol.32
    • Dorn, G.1
  • 58
    • 0038449221 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA
    • Klein C. Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA. Gastroenterology 2003; 125: 9-18.
    • (2003) Gastroenterology , vol.125 , pp. 9-18
    • Klein, C.1
  • 59
    • 1542742114 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • DOI 10.1038/sj.onc.1207272
    • Duxbury MS, Ito H, Zinner MJ, et al. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 2004; 23: 1539-1548. (Pubitemid 38406516)
    • (2004) Oncogene , vol.23 , Issue.8 , pp. 1539-1548
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 60
    • 15044348274 scopus 로고    scopus 로고
    • Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo
    • DOI 10.1093/brain/awh382
    • Lingor P, Koeberle P, Kugler S, et al. Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo. Brain 2005; 128: 550-558. (Pubitemid 40380190)
    • (2005) Brain , vol.128 , Issue.3 , pp. 550-558
    • Lingor, P.1    Koeberle, P.2    Kugler, S.3    Bahr, M.4
  • 61
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • DOI 10.1038/nm1164
    • Bitko V, Musiyenko A, Shulyayeva O, et al. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005; 11: 50-55. (Pubitemid 40215837)
    • (2005) Nature Medicine , vol.11 , Issue.1 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 62
    • 24744466699 scopus 로고    scopus 로고
    • Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in rhesus macaque
    • Li BJ. Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in rhesus macaque. Nat Med 2005; 11: 944-951.
    • (2005) Nat Med , vol.11 , pp. 944-951
    • Li, B.J.1
  • 63
  • 64
    • 70349962959 scopus 로고    scopus 로고
    • Pharmaceutical strategies enhancing cell penetration efficiencies of non-viral gene delivery systems
    • Liu C, Zhang N. Pharmaceutical strategies enhancing cell penetration efficiencies of non-viral gene delivery systems. Curr Gene Ther 2009; 9: 267-290.
    • (2009) Curr Gene Ther , vol.9 , pp. 267-290
    • Liu, C.1    Zhang, N.2
  • 65
    • 34248656980 scopus 로고    scopus 로고
    • Gene manipulation through the use of small interfering RNA (siRNA): From in vitro to in vivo applications
    • Lekha DK, Clarke AR. Gene manipulation through the use of small interfering RNA (siRNA): From in vitro to in vivo applications. Adv Drug Del Rev 2007; 59: 87-100.
    • (2007) Adv Drug del Rev , vol.59 , pp. 87-100
    • Lekha, D.K.1    Clarke, A.R.2
  • 66
    • 45849128013 scopus 로고    scopus 로고
    • Viral vectors in cancer immunotherapy: Which vector for which strategy?
    • Collins SA, Guinn BA, Harrison PT, et al. Viral vectors in cancer immunotherapy: which vector for which strategy? Curr Gene Ther 2008; 8: 66-78.
    • (2008) Curr Gene Ther , vol.8 , pp. 66-78
    • Collins, S.A.1    Guinn, B.A.2    Harrison, P.T.3
  • 67
    • 60649100077 scopus 로고    scopus 로고
    • Applications of lentiviral vectors for shRNA delivery and transgenesis
    • Singer O, Verma IM. Applications of lentiviral vectors for shRNA delivery and transgenesis. Curr Gene Ther 2008; 8: 483-488.
    • (2008) Curr Gene Ther , vol.8 , pp. 483-488
    • Singer, O.1    Verma, I.M.2
  • 69
    • 32144452103 scopus 로고    scopus 로고
    • Lentiviral delivery of RNAi in hippocampal neurons
    • DOI 10.1016/S0076-6879(06)06046-0, PII S0076687906060460, 46, Regulators and Effectors of Small GTPases: Rho Family
    • Janas J, Skowronski J, Van Aelst L. Lentiviral delivery of RNAi in hippocampal neurons. Methods Enzymol 2006; 406: 593-605. (Pubitemid 43207471)
    • (2006) Methods in Enzymology , vol.406 , pp. 593-605
    • Janas, J.1    Skowronski, J.2    Van Aelst, L.3
  • 71
    • 0037468660 scopus 로고    scopus 로고
    • Gene silencing by adenovirus-delivered siRNA
    • Shen C, Buck AK, Liu X. et al. Gene silencing by adenovirus-delivered siRNA. FEBS Lett 2003; 539: 111-114.
    • (2003) FEBS Lett , vol.539 , pp. 111-114
    • Shen, C.1    Buck, A.K.2    Liu, X.3
  • 72
    • 31944441562 scopus 로고    scopus 로고
    • Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensinAT1a receptors inmouse brain
    • Chen Y, Chen H, Hoffmann A, et al. Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensinAT1a receptors inmouse brain. Hypertension 2006; 47: 230-237.
    • (2006) Hypertension , vol.47 , pp. 230-237
    • Chen, Y.1    Chen, H.2    Hoffmann, A.3
  • 73
    • 19644375195 scopus 로고    scopus 로고
    • Adenovirus-mediated silencing of huntingtin expression by shRNA
    • DOI 10.1089/hum.2005.16.618
    • Huang B, Kochanek S. Adenovirus-mediated silencing of huntingtin expression by shRNA. Hum Gene Ther 2005; 16: 618-626. (Pubitemid 40740929)
    • (2005) Human Gene Therapy , vol.16 , Issue.5 , pp. 618-626
    • Huang, B.1    Kochanek, S.2
  • 75
    • 34548532823 scopus 로고    scopus 로고
    • Targeted delivery systems of small interfering RNA by systemic administration
    • Kawakami S, Hashida M. Targeted delivery systems of small interfering RNA by systemic administration. Drug Metab Pharmacokinet 2007; 22: 142-151.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 142-151
    • Kawakami, S.1    Hashida, M.2
  • 76
    • 59249105606 scopus 로고    scopus 로고
    • Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes
    • Midoux P, Breuzard G, Gomez JP et al. Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes. Curr Gene Ther 2008; 8: 335-352.
    • (2008) Curr Gene Ther , vol.8 , pp. 335-352
    • Midoux, P.1    Breuzard, G.2    Gomez, J.P.3
  • 77
    • 59249099019 scopus 로고    scopus 로고
    • Extracellular targeting of synthetic therapeutic nucleic acid formulations
    • Philipp A, Meyer M, Wagner E. Extracellular targeting of synthetic therapeutic nucleic acid formulations. Curr Gene Ther 2008; 8: 324-334.
    • (2008) Curr Gene Ther , vol.8 , pp. 324-334
    • Philipp, A.1    Meyer, M.2    Wagner, E.3
  • 78
    • 0034294817 scopus 로고    scopus 로고
    • Development of biomaterials for gene therapy
    • Han S, Mahato RI, Sung YK, et al. Development of biomaterials for gene therapy. Mol Ther 2000; 2: 302-317.
    • (2000) Mol Ther , vol.2 , pp. 302-317
    • Han, S.1    Mahato, R.I.2    Sung, Y.K.3
  • 79
    • 65349088500 scopus 로고    scopus 로고
    • Systemic therapeutic gene delivery for cancer: Crafting Paris' Arrow
    • Tong AW, Jay CM, Senzer N et al. Systemic therapeutic gene delivery for cancer: crafting Paris' Arrow. Curr Gene Ther 2009; 9: 45-60.
    • (2009) Curr Gene Ther , vol.9 , pp. 45-60
    • Tong, A.W.1    Jay, C.M.2    Senzer, N.3
  • 80
    • 33646685202 scopus 로고    scopus 로고
    • Delivery strategies for siRNA-mediated gene silencing
    • DOI 10.2174/156720106776359159
    • Gilmore IR, Fox SP, Hollins AJ et al. Delivery strategies for siRNA-mediated gene silencing. Curr Drug Deliv 2006; 3: 147-155. (Pubitemid 43738986)
    • (2006) Current Drug Delivery , vol.3 , Issue.2 , pp. 147-155
    • Gilmore, I.R.1    Fox, S.P.2    Hollins, A.J.3    Akhtar, S.4
  • 81
    • 0023447252 scopus 로고
    • Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
    • Felgner PL, Gadek TR, Holm M, et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7417.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7413-7417
    • Felgner, P.L.1    Gadek, T.R.2    Holm, M.3
  • 83
    • 1942534976 scopus 로고    scopus 로고
    • "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes
    • Fattal E, Couvreur P, Dubernet C. "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. Adv Drug Deliv Rev 2004; 56: 931-946.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 931-946
    • Fattal, E.1    Couvreur, P.2    Dubernet, C.3
  • 84
    • 59249085987 scopus 로고    scopus 로고
    • Progress in cationic lipid-mediated gene transfection: A series of bio-inspired lipids as an example
    • Montier T, Benvegnu T, Jaffres PA, et al. Progress in cationic lipid-mediated gene transfection: A series of bio-inspired lipids as an example. Curr Gene Ther 2008; 8: 296-312.
    • (2008) Curr Gene Ther , vol.8 , pp. 296-312
    • Montier, T.1    Benvegnu, T.2    Jaffres, P.A.3
  • 85
    • 34247855110 scopus 로고    scopus 로고
    • Nonviral gene delivery: What we know and what is next
    • Gao X, Kim KS, Liu D. Nonviral gene delivery: What we know and what is next. AAPS J 2007; 9: E92-103.
    • (2007) AAPS J , vol.9
    • Gao, X.1    Kim, K.S.2    Liu, D.3
  • 87
    • 2342530994 scopus 로고    scopus 로고
    • Advanced transfection with Lipofectamine 2000 reagent: Primary neurons, siRNA, and high-throughput applications
    • Dalby B, Cates S, Harris A, et al. Advanced transfection with Lipofectamine 2000 reagent: primary neurons, siRNA, and high-throughput applications. Methods 2004; 33: 95-103.
    • (2004) Methods , vol.33 , pp. 95-103
    • Dalby, B.1    Cates, S.2    Harris, A.3
  • 88
    • 6344291687 scopus 로고    scopus 로고
    • Lipidic carriers of siRNA: Differences in the formulation, cellular uptake, and delivery with plasmid DNA
    • Spagnou S, Miller AD, Keller M. Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA. Biochemistry 2004; 43: 13348-13356. (Pubitemid 39391135)
    • (2004) Biochemistry , vol.43 , Issue.42 , pp. 13348-13356
    • Spagnou, S.1    Miller, A.D.2    Keller, M.3
  • 89
    • 59249088227 scopus 로고    scopus 로고
    • Physicochemical parameters of non-viral vectors that govern transfection efficiency
    • Barteau B, Chevre R, Letrou-Bonneval E, et al. Physicochemical parameters of non-viral vectors that govern transfection efficiency. Curr Gene Ther 2008; 8: 313-323.
    • (2008) Curr Gene Ther , vol.8 , pp. 313-323
    • Barteau, B.1    Chevre, R.2    Letrou-Bonneval, E.3
  • 91
    • 34247181222 scopus 로고    scopus 로고
    • Gene delivery by cationic lipid vectors: Overcoming cellular barriers
    • DOI 10.1007/s00249-006-0092-4, Klaus Arnold Special Issue
    • Zuhorn IS, Engberts JBFN, Hoekstra D. Gene delivery by cationic lipid vectors: overcoming cellular barriers. Eur Biophys J 2007; 36: 349-362. (Pubitemid 46626209)
    • (2007) European Biophysics Journal , vol.36 , Issue.4-5 , pp. 349-362
    • Zuhorn, I.S.1    Engberts, J.B.F.N.2    Hoekstra, D.3
  • 92
    • 0029949266 scopus 로고    scopus 로고
    • Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
    • DOI 10.1021/bi9602019
    • Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35: 5616-5623. (Pubitemid 26143656)
    • (1996) Biochemistry , vol.35 , Issue.18 , pp. 5616-5623
    • Xu, Y.1    Szoka Jr., F.C.2
  • 93
    • 0029067792 scopus 로고
    • The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
    • Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1995; 1235: 289-295.
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 289-295
    • Farhood, H.1    Serbina, N.2    Huang, L.3
  • 94
    • 0029019120 scopus 로고
    • Fusion of cationic liposomes with mammalian cells occurs after endocytosis
    • Wrobel I, Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1995; 1235: 296-304.
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 296-304
    • Wrobel, I.1    Collins, D.2
  • 95
    • 0041821538 scopus 로고    scopus 로고
    • Lipid bilayer vesicle fusion: Intermediates captured by highspeed microfluorescence spectroscopy
    • Lei G, MacDonald RC. Lipid bilayer vesicle fusion: intermediates captured by high-speed microfluorescence spectroscopy. Biophys J 2003; 85:1585-1599. (Pubitemid 37052244)
    • (2003) Biophysical Journal , vol.85 , Issue.3 , pp. 1585-1599
    • Lei, G.1    MacDonald, R.C.2
  • 97
    • 0033990408 scopus 로고    scopus 로고
    • In vitro transport and delivery of antisense oligonucleotides
    • Hughes J, Astriab A, Yoo H, et al. In vitro transport and delivery of antisense oligonucleotides. Methods Enzymol 2000; 313: 342-358.
    • (2000) Methods Enzymol , vol.313 , pp. 342-358
    • Hughes, J.1    Astriab, A.2    Yoo, H.3
  • 98
    • 0026497428 scopus 로고
    • Effect of cationic cholesterol derivatives on gene-transfer and protein-kinase-C activity
    • Farhood H, Bottega R, Epand RM, et al. Effect of cationic cholesterol derivatives on gene-transfer and protein-kinase-C activity. Biochim Biophys Acta 1992; 1111: 239-246.
    • (1992) Biochim Biophys Acta , vol.1111 , pp. 239-246
    • Farhood, H.1    Bottega, R.2    Epand, R.M.3
  • 99
    • 0029856329 scopus 로고    scopus 로고
    • Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
    • DOI 10.1023/A:1016026101195
    • Zelphati O, Szoka FC. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids. Pharm Res 1996; 13: 1367-1372. (Pubitemid 26344983)
    • (1996) Pharmaceutical Research , vol.13 , Issue.9 , pp. 1367-1372
    • Zelphati, O.1    Szoka Jr., F.C.2
  • 100
    • 0031559941 scopus 로고    scopus 로고
    • The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids
    • DOI 10.1016/S0014-5793(97)00973-3, PII S0014579397009733
    • Ouahabi A, Thiry M, Pector V. The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids. FEBS Lett 1997; 414: 187-192. (Pubitemid 27389360)
    • (1997) FEBS Letters , vol.414 , Issue.2 , pp. 187-192
    • El Ouahabi, A.1    Thiry, M.2    Pector, V.3    Fuks, R.4    Ruysschaert, J.M.5    Vandenbranden, M.6
  • 102
    • 0028072689 scopus 로고
    • New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy
    • DOI 10.1016/0014-5793(94)01315-2
    • Sternberg B, Sorgi FL, Huang L. et al. New structures in complex formation between DNA and cationic liposomes visualized by freezefracture electron microscopy. FEBS Lett 1994; 356: 361-366. (Pubitemid 24377008)
    • (1994) FEBS Letters , vol.356 , Issue.2-3 , pp. 361-366
    • Sternberg, B.1
  • 103
    • 0037622183 scopus 로고    scopus 로고
    • Three-dimensional imaging of lipid gene-carriers: Membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes
    • Lin AJ, Slack NL, Ahmad A. et al. Three-dimensional imaging of lipid gene-carriers: membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes. Biophys J 2003; 84: 3307-3316. (Pubitemid 36531778)
    • (2003) Biophysical Journal , vol.84 , Issue.5 , pp. 3307-3316
    • Lin, A.J.1    Slack, N.L.2    Ahmad, A.3    George, C.X.4    Samuel, C.E.5    Safinya, C.R.6
  • 105
    • 33846846570 scopus 로고    scopus 로고
    • Liposomes for phospholipase A2 triggered siRNA release: Preparation and in vitro test
    • Foged C, Nielsen HM, Frokjaer S. Liposomes for phospholipase A2 triggered siRNA release: Preparation and in vitro test. Int J Pharm 2007; 331: 160-166.
    • (2007) Int J Pharm , vol.331 , pp. 160-166
    • Foged, C.1    Nielsen, H.M.2    Frokjaer, S.3
  • 106
    • 60049089373 scopus 로고    scopus 로고
    • Development of a novel method for formulating stable siRNA-loaded lipid particles for in vivo use
    • Wu SY, Putral LN, Liang M, et al. Development of a novel method for formulating stable siRNA-loaded lipid particles for in vivo use. Pharm Res 2009; 26: 512-522.
    • (2009) Pharm Res , vol.26 , pp. 512-522
    • Wu, S.Y.1    Putral, L.N.2    Liang, M.3
  • 107
    • 48749092347 scopus 로고    scopus 로고
    • Gene delivery to dendritic cells mediated by complexes of lipoplexes and pH-sensitive fusogenic polymer-modified liposomes
    • Yuba E, Kojima C, Sakaguchi N, et al. Gene delivery to dendritic cells mediated by complexes of lipoplexes and pH-sensitive fusogenic polymer-modified liposomes. J Control Release 2008; 130:77-83.
    • (2008) J Control Release , vol.130 , pp. 77-83
    • Yuba, E.1    Kojima, C.2    Sakaguchi, N.3
  • 108
    • 50949095169 scopus 로고    scopus 로고
    • Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes
    • Auguste DT, Furman K, Wong A, et al. Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes. J Control Release 2008; 130: 266-274.
    • (2008) J Control Release , vol.130 , pp. 266-274
    • Auguste, D.T.1    Furman, K.2    Wong, A.3
  • 109
  • 110
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • DOI 10.1016/S0022-2836(03)00181-5
    • Sorensen DR, Leirdal M, Sioud M, Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 2003; 327: 761-766. (Pubitemid 36315917)
    • (2003) Journal of Molecular Biology , vol.327 , Issue.4 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 112
    • 33847153016 scopus 로고    scopus 로고
    • The gene-silencing effect of siRNA in cationic lipoplexes is enhanced by incorporating pDNA in the complex
    • DOI 10.1016/j.ijpharm.2006.09.057, PII S0378517306008040
    • Tagami T, Barichello JM, Kikuchi H, et al. The gene-silencing effect of siRNA in cationic lipoplexes is enhanced by incorporating pDNA in the complex. Int J Pharm 2007; 333: 62-69. (Pubitemid 46283268)
    • (2007) International Journal of Pharmaceutics , vol.333 , Issue.1-2 , pp. 62-69
    • Tagami, T.1    Barichello, J.M.2    Kikuchi, H.3    Ishida, T.4    Kiwada, H.5
  • 114
    • 33644839698 scopus 로고    scopus 로고
    • siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway
    • Miyawaki-Shimizu K, Predescu D, Shimizu J, et al. siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol 2006; 290: L405-L413.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Miyawaki-Shimizu, K.1    Predescu, D.2    Shimizu, J.3
  • 115
    • 23044506285 scopus 로고    scopus 로고
    • Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
    • Landen CN, Chavez-Reyes A, Bucana C, et al. Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery. Cancer Res 2005; 65: 6910-6918.
    • (2005) Cancer Res , vol.65 , pp. 6910-6918
    • Landen, C.N.1    Chavez-Reyes, A.2    Bucana, C.3
  • 116
    • 33845654382 scopus 로고    scopus 로고
    • Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice
    • DOI 10.1016/j.biomaterials.2006.11.010, PII S0142961206009598
    • Sato A, Takagi M, Shimamoto A, et al. Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice, Biomaterials 2007; 28: 1434-1442. (Pubitemid 44959042)
    • (2007) Biomaterials , vol.28 , Issue.7 , pp. 1434-1442
    • Sato, A.1    Takagi, M.2    Shimamoto, A.3    Kawakami, S.4    Hashida, M.5
  • 117
    • 15444376742 scopus 로고    scopus 로고
    • Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo
    • Flynn MA, Casey DG. Todryk SM. Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo. J Inflammation 2004; 1: 1-12.
    • (2004) J Inflammation , vol.1 , pp. 1-12
    • Flynn, M.A.1    Casey, D.G.2    Todryk, S.M.3
  • 118
    • 34247395828 scopus 로고    scopus 로고
    • Cellular selivery of siRNA mediated by fusion-active virosomes
    • DOI 10.1080/08982100601186516, PII 777382827
    • Huckriede A, Jonge JD, Holtrop M et al. Cellular delivery of siRNA mediated by fusion-active virosomes. J. Liposome Res 2007; 17: 39-47. (Pubitemid 46631137)
    • (2007) Journal of Liposome Research , vol.17 , Issue.1 , pp. 39-47
    • Huckriede, A.1    De Jonge, J.2    Holtrop, M.3    Wilschut, J.4
  • 119
    • 34248644581 scopus 로고    scopus 로고
    • Octaarginine-modified multifunctional envelope-type nano device for siRNA
    • DOI 10.1016/j.jconrel.2007.03.010, PII S0168365907001447
    • Nakamura Y, Kogure K, Futaki S et al. Octaarginine-modified multifunctional envelope-type nano device for siRNA. J Control Release 2007; 119: 360-367. (Pubitemid 46770881)
    • (2007) Journal of Controlled Release , vol.119 , Issue.3 , pp. 360-367
    • Nakamura, Y.1    Kogure, K.2    Futaki, S.3    Harashima, H.4
  • 120
    • 69949155656 scopus 로고    scopus 로고
    • A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo
    • Hatakeyama H, Ito E, Akita H, et al. A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo. J Control Release 2009; 139: 127-132.
    • (2009) J Control Release , vol.139 , pp. 127-132
    • Hatakeyama, H.1    Ito, E.2    Akita, H.3
  • 121
    • 33845365806 scopus 로고    scopus 로고
    • Specific beta1-adrenergic receptor silencing with small interfering RNA lowers high blood pressure and improves cardiac function in myocardial ischemia
    • Arnold AS. Specific beta1-adrenergic receptor silencing with small interfering RNA lowers high blood pressure and improves cardiac function in myocardial ischemia. J Hypertens 2007; 25: 197-205.
    • (2007) J Hypertens , vol.25 , pp. 197-205
    • Arnold, A.S.1
  • 123
    • 22644439250 scopus 로고    scopus 로고
    • Systemic delivery of RafsiRNA using cationic cardiolipin liposomes silences Raf- 1 expression and inhibits tumor growth in xenograft model of human prostate cancer
    • Pal A. Systemic delivery of RafsiRNA using cationic cardiolipin liposomes silences Raf- 1 expression and inhibits tumor growth in xenograft model of human prostate cancer. Int J Oncol 2005; 26: 1087-1091.
    • (2005) Int J Oncol , vol.26 , pp. 1087-1091
    • Pal, A.1
  • 124
    • 24944455101 scopus 로고    scopus 로고
    • Silencing heat shock factor 1 by small interfering RNA abrogates heat shock-induced cardioprotection against ischemia-reperfusion injury in mice
    • DOI 10.1016/j.yjmcc.2005.06.005, PII S0022282805001896
    • Yin C, Xi L, Wang X. et al. Silencing heat shock factor 1 by small interfering RNA abrogates heat shock-induced cardioprotection against ischemia-reperfusion injury in mice. J Mol Cell Cardiol 2005; 39: 681-689. (Pubitemid 41331056)
    • (2005) Journal of Molecular and Cellular Cardiology , vol.39 , Issue.4 , pp. 681-689
    • Yin, C.1    Xi, L.2    Wang, X.3    Eapen, M.4    Kukreja, R.C.5
  • 125
    • 14644413531 scopus 로고    scopus 로고
    • Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo
    • Chien PY. Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo. Cancer Gene Ther 2005; 12: 321-328.
    • (2005) Cancer Gene Ther , vol.12 , pp. 321-328
    • Chien, P.Y.1
  • 127
    • 34248228071 scopus 로고    scopus 로고
    • Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system
    • Pirollo KF. Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system. Cancer Res 2007; 67: 2938-2943.
    • (2007) Cancer Res , vol.67 , pp. 2938-2943
    • Pirollo, K.F.1
  • 129
    • 33749681890 scopus 로고    scopus 로고
    • Delivery of RNA Interference
    • Li CX, Parker A, Menocal E, et al. Delivery of RNA Interference. Cell Cycle 2006; 5: 2103-9
    • (2006) Cell Cycle , vol.5 , pp. 2103-2109
    • Li, C.X.1    Parker, A.2    Menocal, E.3
  • 130
    • 34547228805 scopus 로고    scopus 로고
    • Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery
    • DOI 10.1016/j.jconrel.2007.05.021, PII S0168365907002659
    • Gary DJ, Puri N, Won YY. Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. J Control Release 2007; 121: 64-73. (Pubitemid 47126065)
    • (2007) Journal of Controlled Release , vol.121 , Issue.1-2 , pp. 64-73
    • Gary, D.J.1    Puri, N.2    Won, Y.-Y.3
  • 131
    • 33746864903 scopus 로고    scopus 로고
    • Synthetic peptides as non-viral DNA vectors
    • DOI 10.2174/156652306777934865
    • Fabre JW, Collins L. Synthetic peptides as non-viral DNA vectors. Curr Gene Ther 2006; 6: 459-480. (Pubitemid 44194391)
    • (2006) Current Gene Therapy , vol.6 , Issue.4 , pp. 459-480
    • Fabre, J.W.1    Collins, L.2
  • 132
    • 48949098577 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Synthetic polymer-based systems
    • Schaffert D, Wagner E. Gene therapy progress and prospects: synthetic polymer-based systems. Gene Ther 2008; 15: 1131-1138.
    • (2008) Gene Ther , vol.15 , pp. 1131-1138
    • Schaffert, D.1    Wagner, E.2
  • 133
    • 34548532823 scopus 로고    scopus 로고
    • Targeted delivery systems of small interfering RNA by systemic administration
    • Kawakami S, Hashida M. Targeted delivery systems of small interfering RNA by systemic administration. Drug Metab Pharmacokinet 2007; 22: 142-151.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 142-151
    • Kawakami, S.1    Hashida, M.2
  • 134
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualc'h F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA 1995; 92: 7297-7301.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'H, F.2    Zanta, M.A.3
  • 136
    • 0038004448 scopus 로고    scopus 로고
    • A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity
    • DOI 10.1023/A:1014861900478
    • Fischer D, Bieber T, Li Y, et al. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 1999; 16: 1273-1279. (Pubitemid 29393618)
    • (1999) Pharmaceutical Research , vol.16 , Issue.8 , pp. 1273-1279
    • Fischer, D.1    Bieber, T.2    Li, Y.3    Elsasser, H.-P.4    Kissel, T.5
  • 137
    • 33646152761 scopus 로고    scopus 로고
    • A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
    • Werth S, Urban-Klein B, Dai L, et al. A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes, J Control Release 2006; 112: 257-270.
    • (2006) J Control Release , vol.112 , pp. 257-270
    • Werth, S.1    Urban-Klein, B.2    Dai, L.3
  • 138
    • 33748208710 scopus 로고    scopus 로고
    • PEI-alginate nanocomposites as efficient in vitro gene transfection agents
    • Patnaik S, Aggarwal A, Nimesh S, et al. PEI-alginate nanocomposites as efficient in vitro gene transfection agents. J Control Release 2006; 114: 398-409.
    • (2006) J Control Release , vol.114 , pp. 398-409
    • Patnaik, S.1    Aggarwal, A.2    Nimesh, S.3
  • 140
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
    • DOI 10.1038/sj.gt.3302425
    • Urban-Klein B, Werth S, Abuharbeid S, et al. RNAi mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther 2005; 12: 461-466. (Pubitemid 40394299)
    • (2005) Gene Therapy , vol.12 , Issue.5 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4    Aigner, A.5
  • 141
    • 33746871883 scopus 로고    scopus 로고
    • Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro
    • DOI 10.1007/s11095-006-9009-2
    • Grayson AC, Doody AM, Putnam D, et al. Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro. Pharm Res 2006; 23: 1868-1876. (Pubitemid 44200551)
    • (2006) Pharmaceutical Research , vol.23 , Issue.8 , pp. 1868-1876
    • Richards Grayson, A.C.1    Doody, A.M.2    Putnam, D.3
  • 142
    • 47749100430 scopus 로고    scopus 로고
    • Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity
    • Zintchenko A, Philipp A, Dehshahri A, et al. Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity. Bioconjug Chem 2008; 19: 1448-55.
    • (2008) Bioconjug Chem , vol.19 , pp. 1448-1455
    • Zintchenko, A.1    Philipp, A.2    Dehshahri, A.3
  • 143
    • 0037161323 scopus 로고    scopus 로고
    • Biodegradable poly (ethylenimine) for plasmid DNA delivery
    • Ahn CH, Chae SY, Bae YH, et al. Biodegradable poly (ethylenimine) for plasmid DNA delivery. J Control Release 2002; 80: 273-282.
    • (2002) J Control Release , vol.80 , pp. 273-282
    • Ahn, C.H.1    Chae, S.Y.2    Bae, Y.H.3
  • 144
    • 33947302736 scopus 로고    scopus 로고
    • Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy
    • DOI 10.1016/j.jconrel.2006.12.026, PII S0168365907000028
    • Kim WJ, Chang CW, Lee M, et al. Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy. J Control Release 2007; 118: 357-363. (Pubitemid 46441547)
    • (2007) Journal of Controlled Release , vol.118 , Issue.3 , pp. 357-363
    • Kim, W.J.1    Chang, C.-W.2    Lee, M.3    Kim, S.W.4
  • 145
    • 33846302477 scopus 로고    scopus 로고
    • Reducible poly (amido ethylenimine) directed to enhance RNA interference
    • Jeong JH, Christensen LV, Yockman JW, et al. Reducible poly (amido ethylenimine) directed to enhance RNA interference. Biomaterials 2007; 28: 1912-1917.
    • (2007) Biomaterials , vol.28 , pp. 1912-1917
    • Jeong, J.H.1    Christensen, L.V.2    Yockman, J.W.3
  • 146
    • 48749113674 scopus 로고    scopus 로고
    • Mechanistic investigation of poly (ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo
    • Breunig M, Hozsa C, Lungwitz CU, et al. Mechanistic investigation of poly (ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo. J Control Release 2008; 130: 57-63.
    • (2008) J Control Release , vol.130 , pp. 57-63
    • Breunig, M.1    Hozsa, C.2    Lungwitz, C.U.3
  • 147
    • 70449708980 scopus 로고    scopus 로고
    • Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel
    • Liu C, Zhao G, Liu et al. Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. J Control Release 2009; 140: 277-283.
    • (2009) J Control Release , vol.140 , pp. 277-283
    • Liu, C.1    Liu, Z.G.2
  • 148
    • 73449085169 scopus 로고    scopus 로고
    • Progress and prospects of chitosan and its derivatives as non viral gene vectors in gene therapy
    • Tong H, Shi Q, Fernandes JC, et al. Progress and prospects of chitosan and its derivatives as non viral gene vectors in gene therapy. Curr Gene Ther 2009; 9: 495-502.
    • (2009) Curr Gene Ther , vol.9 , pp. 495-502
    • Tong, H.1    Shi, Q.2    Fernandes, J.C.3
  • 151
    • 33749844509 scopus 로고    scopus 로고
    • Development and characterisation of chitosan nanoparticles for siRNA delivery
    • DOI 10.1016/j.jconrel.2006.07.021, PII S0168365906003683
    • Katas H, Alpar HO. Development and characterization of chitosan nanoparticles for siRNA delivery. J Control Release 2006; 115: 216-225. (Pubitemid 44559708)
    • (2006) Journal of Controlled Release , vol.115 , Issue.2 , pp. 216-225
    • Katas, H.1    Alpar, H.O.2
  • 152
    • 33845975678 scopus 로고    scopus 로고
    • Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference
    • DOI 10.1016/j.biomaterials.2006.11.018, PII S0142961206009628
    • Tan WB, Jiang S, Zhang Y. Quantum-dot based nanoparticles for targeted silencing of HER2/neugene via RNA interference. Biomaterials 2007; 28: 1565-1571. (Pubitemid 46039833)
    • (2007) Biomaterials , vol.28 , Issue.8 , pp. 1565-1571
    • Tan, W.B.1    Jiang, S.2    Zhang, Y.3
  • 153
    • 67650608146 scopus 로고    scopus 로고
    • Efficient chitosan-graft-polyethylenimine for Akt1 siRNA delivery to non small cell lung carcinoma cell line
    • Jere D, Jiang HL, Xu CX, et al. Efficient chitosan-graft-polyethylenimine for Akt1 siRNA delivery to non small cell lung carcinoma cell line. Int J Pharm 2009; 378: 194-200.
    • (2009) Int J Pharm , vol.378 , pp. 194-200
    • Jere, D.1    Jiang, H.L.2    Xu, C.X.3
  • 155
    • 33748054817 scopus 로고    scopus 로고
    • RNA interference in vitro and in vivo using a chitosan/siRNA Nanoparticle system
    • Howard K, Kjems J. RNA interference in vitro and in vivo using a chitosan/siRNA Nanoparticle system. Mol Ther 2006; 14: 476-484.
    • (2006) Mol Ther , vol.14 , pp. 476-484
    • Howard, K.1    Kjems, J.2
  • 156
    • 39549120024 scopus 로고    scopus 로고
    • Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles
    • Bartlett DW, Davis ME. Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles. Biotechnol Bioeng 2008; 99: 975-985.
    • (2008) Biotechnol Bioeng , vol.99 , pp. 975-985
    • Bartlett, D.W.1    Davis, M.E.2
  • 157
    • 25444482607 scopus 로고    scopus 로고
    • Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
    • DOI 10.1158/0008-5472.CAN-05-0565
    • Hu-Lieskovan S, Heidel JD, Bartlett DW. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in murine model of metastatic Ewing's sarcoma. Cancer Res 2005; 65: 8984-8992. (Pubitemid 41377390)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8984-8992
    • Hu-Lieskovan, S.1    Heidel, J.D.2    Bartlett, D.W.3    Davis, M.E.4    Triche, T.J.5
  • 159
    • 25444482607 scopus 로고    scopus 로고
    • Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
    • DOI 10.1158/0008-5472.CAN-05-0565
    • Hu-Lieskovan S, Heidel JD, Bartlett DW et al. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res 2005; 65: 8984-8992. (Pubitemid 41377390)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8984-8992
    • Hu-Lieskovan, S.1    Heidel, J.D.2    Bartlett, D.W.3    Davis, M.E.4    Triche, T.J.5
  • 161
    • 34347272315 scopus 로고    scopus 로고
    • Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
    • Heidel JD, et al. Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA. Proc Natl Acad Sci USA 2007; 104: 5715-5721.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5715-5721
    • Heidel, J.D.1
  • 162
    • 59849090457 scopus 로고    scopus 로고
    • Cellular Delivery in vivo of siRNA-based therapeutics
    • Aigner A, Cellular Delivery in vivo of siRNA-based therapeutics. Curr Pharm Des 2008; 14: 3603-3619.
    • (2008) Curr Pharm Des , vol.14 , pp. 3603-3619
    • Aigner, A.1
  • 163
    • 0033000907 scopus 로고    scopus 로고
    • New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: The Minipellet
    • Ochiya T, Takahama Y, Nagahara S, et al. New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet. Nat Med 1999; 5: 707-710.
    • (1999) Nat Med , vol.5 , pp. 707-710
    • Ochiya, T.1    Takahama, Y.2    Nagahara, S.3
  • 164
    • 3242733298 scopus 로고    scopus 로고
    • Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
    • Minakuchi Y, Takeshita F, Kosaka N, et al. Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 2004; 32: e109.
    • (2004) Nucleic Acids Res , vol.32
    • Minakuchi, Y.1    Takeshita, F.2    Kosaka, N.3
  • 165
    • 33747177852 scopus 로고    scopus 로고
    • Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts
    • DOI 10.1002/cncr.22068
    • Takei Y, Kadomatsu K, Goto T, Muramatsu T. Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts. Cancer 2006; 107: 864-873. (Pubitemid 44232679)
    • (2006) Cancer , vol.107 , Issue.4 , pp. 864-873
    • Takei, Y.1    Kadomatsu, K.2    Goto, T.3    Muramatsu, T.4
  • 166
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • DOI 10.1158/0008-5472.CAN-03-2682
    • Takei Y, Kadomatsu K, Yuzawa Y, et al. Small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 2004; 64: 3365-3370. (Pubitemid 38657905)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3    Matsuo, S.4    Muramatsu, T.5
  • 170
    • 72149100454 scopus 로고    scopus 로고
    • PEI-alginate nanocomposites: Efficient non-viral vectors for nucleic acids
    • Patnaik S, Arif M, Pathak A et al. PEI-alginate nanocomposites: efficient non-viral vectors for nucleic acids. Int J Pharm 2010; 385(1-2):194-202.
    • (2010) Int J Pharm , vol.385 , Issue.1-2 , pp. 194-202
    • Patnaik, S.1    Arif, M.2    Pathak, A.3
  • 171
    • 69949128210 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery
    • Lee DW, Yun KS, Ban HS, et al. Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery. J Control Release 2009; 139(2):146-152.
    • (2009) J Control Release , vol.139 , Issue.2 , pp. 146-152
    • Lee, D.W.1    Yun, K.S.2    Ban, H.S.3
  • 172
    • 67649948772 scopus 로고    scopus 로고
    • Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels
    • Krebs MD, Jeon O, Alsberg E. Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels, J Am Chem Soc 2009; 131 (26): 9204-9206.
    • (2009) J Am Chem Soc , vol.131 , Issue.26 , pp. 9204-9206
    • Krebs, M.D.1    Jeon, O.2    Alsberg, E.3
  • 174
    • 56849117151 scopus 로고    scopus 로고
    • Fast degrading polyesters as siRNA nanocarriers for pulmonary gene therapy
    • Nguyen J, Steele TWJ, Merkel O et al. Fast degrading polyesters as siRNA nanocarriers for pulmonary gene therapy. J Control Release 2008; 132: 243-251.
    • (2008) J Control Release , vol.132 , pp. 243-251
    • Nguyen, J.1    Steele, T.W.J.2    Merkel, O.3
  • 175
    • 58249112846 scopus 로고    scopus 로고
    • Polymeric nanoparticles for siRNA delivery and gene silencing
    • Patil Y, Panyamb J. Polymeric nanoparticles for siRNA delivery and gene silencing. Int J Pharm 2009; 367: 195-203.
    • (2009) Int J Pharm , vol.367 , pp. 195-203
    • Patil, Y.1    Panyamb, J.2
  • 176
    • 60649114699 scopus 로고    scopus 로고
    • Polymersome delivery of siRNA and antisense oligonucleotides
    • Kim Y, Tewari M, Pajerowski JD et al. Polymersome delivery of siRNA and antisense oligonucleotides.J Control Release 2009; 134: 132-140.
    • (2009) J Control Release , vol.134 , pp. 132-140
    • Kim, Y.1    Tewari, M.2    Pajerowski, J.D.3
  • 177
    • 29444440132 scopus 로고    scopus 로고
    • Bio-functional inorganic materials: An attractive branch of gene-based nano-medicine delivery for 21st century
    • DOI 10.2174/156652305774964613
    • Chowdhury EH, Akaike T. Bio-functional inorganic materials: An attractive branch of gene-based nano-medicine delivery for 21st Century. Curr Gene Ther 2005; 5: 669-676. (Pubitemid 43009510)
    • (2005) Current Gene Therapy , vol.5 , Issue.6 , pp. 669-676
    • Chowdhury, E.H.1    Akaike, T.2
  • 178
    • 58149357363 scopus 로고    scopus 로고
    • Biopharmaceutics and therapeutic potential of engineered nanomaterials
    • Liang XJ, Chen C, Zhao Y et al. Biopharmaceutics and therapeutic potential of engineered nanomaterials. Curr Drug Metab 2008; 9: 697-709.
    • (2008) Curr Drug Metab , vol.9 , pp. 697-709
    • Liang, X.J.1    Chen, C.2    Zhao, Y.3
  • 179
    • 27744504244 scopus 로고    scopus 로고
    • Applications of carbon nanotubes in drug delivery
    • DOI 10.1016/j.cbpa.2005.10.005, PII S1367593105001389, Biopolymers / Model Systems
    • Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr Opin Chem Biol 2005; 9(6): 674-679. (Pubitemid 41612196)
    • (2005) Current Opinion in Chemical Biology , vol.9 , Issue.6 , pp. 674-679
    • Bianco, A.1    Kostarelos, K.2    Prato, M.3
  • 180
    • 67649890883 scopus 로고    scopus 로고
    • Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model
    • Podesta JE, Al-Jamal KT, Herrero MA, et al. Antitumor activity and prolonged survival by carbon-nanotube-mediated therapeutic siRNA silencing in a human lung xenograft model. Small 2009; 5(10):1176-1185.
    • (2009) Small , vol.5 , Issue.10 , pp. 1176-1185
    • Podesta, J.E.1    Al-Jamal, K.T.2    Herrero, M.A.3
  • 181
    • 40849086143 scopus 로고    scopus 로고
    • Functionalization of carbon nanotubes enables non-covalent binding and
    • Krajcik R, Jung A, Hirsch A, et al. Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes. Biochem Biophys Res Commun 2008; 369(2): 595-602.
    • (2008) Biochem Biophys Res Commun , vol.369 , Issue.2 , pp. 595-602
    • Krajcik, R.1    Jung, A.2    Hirsch, A.3
  • 182
    • 33748340023 scopus 로고    scopus 로고
    • Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth
    • DOI 10.1158/1078-0432.CCR-05-2831
    • Zhang Z, Yang X, Zhang Y, et al. Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth. Clin Cancer Res 2006; 12(16): 4933-4939. (Pubitemid 44338581)
    • (2006) Clinical Cancer Research , vol.12 , Issue.16 , pp. 4933-4939
    • Zhang, Z.1    Yang, X.2    Zhang, Y.3    Zeng, B.4    Wang, S.5    Zhu, T.6    Roden, R.B.S.7    Chen, Y.8    Yang, R.9
  • 184
    • 67749124305 scopus 로고    scopus 로고
    • Gene regulation with polyvalent siRNA-nanoparticle conjugates
    • Giljohann DA, Seferos DS, Prigodich AE, et al. Gene regulation with polyvalent siRNA-nanoparticle conjugates. J Am Chem Soc 2009; 131(6): 2072-2083.
    • (2009) J Am Chem Soc , vol.131 , Issue.6 , pp. 2072-2083
    • Giljohann, D.A.1    Seferos, D.S.2    Prigodich, A.E.3
  • 185
    • 66449127352 scopus 로고    scopus 로고
    • Layer-by-layer assembled gold nanoparticles for siRNA delivery
    • Elbakry A, Zaky A, Liebl R, et al. Layer-by-layer assembled gold nanoparticles for siRNA delivery. Nano Lett 2009; 9(5): 2059-2064.
    • (2009) Nano Lett , vol.9 , Issue.5 , pp. 2059-2064
    • Elbakry, A.1    Zaky, A.2    Liebl, R.3
  • 186
    • 66749180499 scopus 로고    scopus 로고
    • Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery
    • Lee JS, Green JJ, Love KT, et al. Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery. Nano Lett 2009; 9(6): 2402-2406.
    • (2009) Nano Lett , vol.9 , Issue.6 , pp. 2402-2406
    • Lee, J.S.1    Green, J.J.2    Love, K.T.3
  • 187
    • 76749089244 scopus 로고    scopus 로고
    • Gold nanoparticles capped with polyethyleneimine for enhanced siRNA delivery
    • Song WJ, Du JZ, Sun TM, et al. Gold nanoparticles capped with polyethyleneimine for enhanced siRNA delivery. Small 2010; 6(2): 239-246.
    • (2010) Small , vol.6 , Issue.2 , pp. 239-246
    • Song, W.J.1    Du, J.Z.2    Sun, T.M.3
  • 188
    • 70249090327 scopus 로고    scopus 로고
    • Characterization and performance of nucleic acid nanoparticles combined with protamine and gold
    • DeLong RK, Akhtar U, Sallee M, et al. Characterization and performance of nucleic acid nanoparticles combined with protamine and gold. Biomaterials 2009; 30(32): 6451-6459.
    • (2009) Biomaterials , vol.30 , Issue.32 , pp. 6451-6459
    • DeLong, R.K.1    Akhtar, U.2    Sallee, M.3
  • 189
    • 65249105506 scopus 로고    scopus 로고
    • Nanotechnology approach for drug addiction therapy: Gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons
    • Bonoiu AC, Mahajan SD, Ding H, et al. Nanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons. Proc Natl Acad Sci USA 2009; 106(14): 5546-5550.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.14 , pp. 5546-5550
    • Bonoiu, A.C.1    Mahajan, S.D.2    Ding, H.3
  • 190
    • 73249144464 scopus 로고    scopus 로고
    • Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles
    • Ladewig K, Niebert M, Xu ZP et al. Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles. Biomaterials 2010; 31(7): 1821-1829.
    • (2010) Biomaterials , vol.31 , Issue.7 , pp. 1821-1829
    • Ladewig, K.1    Niebert, M.2    Xu, Z.P.3
  • 191
    • 67650904502 scopus 로고    scopus 로고
    • Calcium phosphate nanoparticles for the transfection of cells
    • Kovtun A, Heumann R, Epple M. Calcium phosphate nanoparticles for the transfection of cells. Biomed Mater Eng 2009; 19(2-3): 241-247.
    • (2009) Biomed Mater Eng , vol.19 , Issue.2-3 , pp. 241-247
    • Kovtun, A.1    Heumann, R.2    Epple, M.3
  • 192
    • 77349109732 scopus 로고    scopus 로고
    • Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery
    • Lia J, Chena Y-C, Tsenga Y-C, et al. Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery. J Control Release 2010; 142(3): 416-421.
    • (2010) J Control Release , vol.142 , Issue.3 , pp. 416-421
    • Lia, J.1    Chena, Y.-C.2    Tsenga, Y.-C.3
  • 193
    • 33645241767 scopus 로고    scopus 로고
    • Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer
    • Kakizawa Y, Furukawa S, Ishii A, et al. Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer. J Control Release 2006; 111(3): 368-370.
    • (2006) J Control Release , vol.111 , Issue.3 , pp. 368-370
    • Kakizawa, Y.1    Furukawa, S.2    Ishii, A.3
  • 194
    • 70349964558 scopus 로고    scopus 로고
    • All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery
    • Lee JH, Lee K, Moon SH, et al. All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery. Angew Chem Int Ed Engl 2009; 48(23): 4174-4179.
    • (2009) Angew Chem Int Ed Engl , vol.48 , Issue.23 , pp. 4174-4179
    • Lee, J.H.1    Lee, K.2    Moon, S.H.3
  • 195
    • 58149169021 scopus 로고    scopus 로고
    • Multifunctional magnetic nanocarriers for image-tagged SiRNA delivery to intact pancreatic islets
    • Medarova Z, Kumar M, Ng SW, et al. Multifunctional magnetic nanocarriers for image-tagged SiRNA delivery to intact pancreatic islets. Transplantation 2008; 86(9): 1170-1177.
    • (2008) Transplantation , vol.86 , Issue.9 , pp. 1170-1177
    • Medarova, Z.1    Kumar, M.2    Ng, S.W.3
  • 196
    • 70350639581 scopus 로고    scopus 로고
    • Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs
    • Xia T, Kovochich M, Liong M, et al. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano 2009; 3(10): 3273-3276.
    • (2009) ACS Nano , vol.3 , Issue.10 , pp. 3273-3276
    • Xia, T.1    Kovochich, M.2    Liong, M.3
  • 197
    • 38449109145 scopus 로고    scopus 로고
    • Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA
    • DOI 10.1093/bfgp/elm015
    • Liu B. Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA. Brief Funct Genomics Proteomics 2007; 6: 112-119. (Pubitemid 351721074)
    • (2007) Briefings in Functional Genomics and Proteomics , vol.6 , Issue.2 , pp. 112-119
    • Liu, B.1
  • 198
    • 34547584514 scopus 로고    scopus 로고
    • Applications of RNA interference: Current state and prospects for siRNA-based strategies in vivo
    • DOI 10.1007/s00253-007-0984-y
    • Aigner A. Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo. RNA Appl Microbiol Biotechnol 2007; 76: 9-21. (Pubitemid 47194678)
    • (2007) Applied Microbiology and Biotechnology , vol.76 , Issue.1 , pp. 9-21
    • Aigner, A.1
  • 200
    • 22944466675 scopus 로고    scopus 로고
    • Delivering RNA interference to the mammalian brain
    • DOI 10.2174/1566523054546206
    • Fountaine TM, Wood MJA, Martins RW. Delivering RNA interference to the mammalian brain. Curr Gene Ther 2005; 5: 399-410. (Pubitemid 41052431)
    • (2005) Current Gene Therapy , vol.5 , Issue.4 , pp. 399-410
    • Fountaine, T.M.1    Wood, M.J.A.2    Wade-Martins, R.3
  • 201
    • 65349169532 scopus 로고    scopus 로고
    • Gene therapy approaches to Ataxias
    • Lim F, Diaz-Nido J. Gene therapy approaches to Ataxias. Curr Gene Ther 2009; 9: 1-8.
    • (2009) Curr Gene Ther , vol.9 , pp. 1-8
    • Lim, F.1    Diaz-Nido, J.2
  • 202
    • 54749147546 scopus 로고    scopus 로고
    • RNA interference: New therapeutics in allergic diseases
    • Lee CC, Chiang BL. RNA interference: new therapeutics in allergic diseases. Curr Gene Ther 2008; 8: 236-246.
    • (2008) Curr Gene Ther , vol.8 , pp. 236-246
    • Lee, C.C.1    Chiang, B.L.2
  • 203
    • 59349116903 scopus 로고    scopus 로고
    • Knocking down barriers: Advances in siRNA delivery
    • Whitehead KA, Langer R, Anderson DG. Knocking down barriers: advances in siRNA delivery. Nature 2009; 8: 129-138.
    • (2009) Nature , vol.8 , pp. 129-138
    • Whitehead, K.A.1    Langer, R.2    Anderson, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.