-
1
-
-
33846228446
-
Effects of melatonin and age on gene expression in mouse CNS using microarray analysis
-
Sharman, E.H.; Bondy, S.C.; Sharman, K.Z.; Lahiri, D.; Cotman, C.W.; Perreau, V.M. Effects of melatonin and age on gene expression in mouse CNS using microarray analysis. Neurochem. Int. 2007, 50, 336-344.
-
(2007)
Neurochem. Int
, vol.50
, pp. 336-344
-
-
Sharman, E.H.1
Bondy, S.C.2
Sharman, K.Z.3
Lahiri, D.4
Cotman, C.W.5
Perreau, V.M.6
-
2
-
-
0032806355
-
Increased microglial activation and protein nitration in white matter of the aging monkey
-
Sloane, J.A.; Hollander, W.; Moss, M.B.; Rosene, D.L.; Abraham, C.R. Increased microglial activation and protein nitration in white matter of the aging monkey. Neurobiol. Aging 1999, 20, 395-405.
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 395-405
-
-
Sloane, J.A.1
Hollander, W.2
Moss, M.B.3
Rosene, D.L.4
Abraham, C.R.5
-
3
-
-
42649098547
-
Microglial degeneration in the aging brain-bad news for neurons
-
Streit, W.J.; Miller, K.R.; Lopes, K.O.; Njie, E. Microglial degeneration in the aging brain-bad news for neurons? Front. Biosci. 2008, 13, 3423-3438.
-
(2008)
Front. Biosci
, vol.13
, pp. 3423-3438
-
-
Streit, W.J.1
Miller, K.R.2
Lopes, K.O.3
Njie, E.4
-
4
-
-
33747877627
-
Microglial senescence: Does the brain's immune system have an expiration date?
-
Streit, W.J. Microglial senescence: Does the brain's immune system have an expiration date? Trends Neurosci. 2006, 29, 506-510.
-
(2006)
Trends Neurosci
, vol.29
, pp. 506-510
-
-
Streit, W.J.1
-
5
-
-
77956338790
-
Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo
-
Frank, M.G.; Barrientos, R.M.; Watkins, L.R.; Maier, S.F. Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo. J. Neuroimmunol. 2010, 226, 181-184.
-
(2010)
J. Neuroimmunol
, vol.226
, pp. 181-184
-
-
Frank, M.G.1
Barrientos, R.M.2
Watkins, L.R.3
Maier, S.F.4
-
6
-
-
78149245073
-
Role of inflammation in cognitive impairment: Results of observational epidemiological studies and clinical trials
-
Gorelick, P.B. Role of inflammation in cognitive impairment: Results of observational epidemiological studies and clinical trials. Ann. N. Y. Acad. Sci. 2010, 1207, 155-162.
-
(2010)
Ann. N. Y. Acad. Sci
, vol.1207
, pp. 155-162
-
-
Gorelick, P.B.1
-
7
-
-
77956958953
-
Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy
-
Qian, L.; Flood, P.M.; Hong, J.S. Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy. J. Neural Transm. 2010, 117, 971-979.
-
(2010)
J. Neural Transm
, vol.117
, pp. 971-979
-
-
Qian, L.1
Flood, P.M.2
Hong, J.S.3
-
8
-
-
77955089391
-
Targeting glial cells to elucidate the pathogenesis of Huntington's disease
-
Hsiao, H.Y.; Chern, Y. Targeting glial cells to elucidate the pathogenesis of Huntington's disease. Mol. Neurobiol. 2010, 4, 248-255.
-
(2010)
Mol. Neurobiol
, vol.4
, pp. 248-255
-
-
Hsiao, H.Y.1
Chern, Y.2
-
9
-
-
0037457875
-
Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease
-
Baker, C.A.; Manuelidis, L. Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease. Proc. Nat. Acad. Sci. USA 2003, 100, 675-679.
-
(2003)
Proc. Nat. Acad. Sci. USA
, vol.100
, pp. 675-679
-
-
Baker, C.A.1
Manuelidis, L.2
-
10
-
-
73949132603
-
Neuro inflammation in prion diseases: Concepts and targets for therapeutic intervention
-
Riemer, C.; Gültner, S.; Heise, I.; Holtkamp, N.; Baier, M. Neuro inflammation in prion diseases: Concepts and targets for therapeutic intervention. CNS Neurol. Disord. Drug Target. 2009, 8, 329-341.
-
(2009)
CNS Neurol. Disord. Drug Target
, vol.8
, pp. 329-341
-
-
Riemer, C.1
Gültner, S.2
Heise, I.3
Holtkamp, N.4
Baier, M.5
-
11
-
-
77958516116
-
Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer'S Disease: Studies in an S100B Overexpressing Mouse Model
-
2010, Article ID 153657
-
Shapiro, L.A.; Bialowas-McGoey, L.A.; Whitaker-Azmitia, P.M. Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer'S Disease: Studies in an S100B Overexpressing Mouse Model. Cardiovasc. Psychiat. Neurol. 2010, 2010, Article ID 153657.
-
(2010)
Cardiovasc. Psychiat. Neurol
-
-
Shapiro, L.A.1
Bialowas-McGoey, L.A.2
Whitaker-Azmitia, P.M.3
-
12
-
-
74549169836
-
ER stress in Alzheimer's disease: A novel neuronal trigger for inflammation and Alzheimer's pathology
-
Salminen, A.; Kauppinen, A.; Suuronen, T.; Kaarniranta, K.; Ojala, J. ER stress in Alzheimer's disease: A novel neuronal trigger for inflammation and Alzheimer's pathology. J. Neuroinflammation 2009, 6, 41.
-
(2009)
J. Neuroinflammation
, vol.6
, pp. 41
-
-
Salminen, A.1
Kauppinen, A.2
Suuronen, T.3
Kaarniranta, K.4
Ojala, J.5
-
13
-
-
77953504104
-
Proteinopathy-induced neuronal senescence: A hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases
-
Golde, T.E.; Miller, V.M. Proteinopathy-induced neuronal senescence: A hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases. Alzheimers Res. Ther. 2009, 1, 5.
-
(2009)
Alzheimers Res. Ther
, vol.1
, pp. 5
-
-
Golde, T.E.1
Miller, V.M.2
-
14
-
-
36248968668
-
Heat shock proteins and amateur chaperones in amyloid-beta accumulation and clearance in Alzheimer's disease
-
Wilhelmus, M.M.; de Waal, R.M.W.; Verbeek, M.M. Heat shock proteins and amateur chaperones in amyloid-beta accumulation and clearance in Alzheimer's disease. Mol. Neurobiol. 2007, 35, 203-216.
-
(2007)
Mol. Neurobiol
, vol.35
, pp. 203-216
-
-
Wilhelmus, M.M.1
de Waal, R.M.W.2
Verbeek, M.M.3
-
15
-
-
38549116650
-
Stress proteins in CNS inflammation
-
van Noort, J.M. Stress proteins in CNS inflammation. J. Pathol. 2008, 214, 267-275.
-
(2008)
J. Pathol
, vol.214
, pp. 267-275
-
-
van Noort, J.M.1
-
16
-
-
77955963249
-
Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation
-
2010, Article ID 587463
-
Linnartz, B.; Wang, Y.; Neumann, H. Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation. Int. J. Alzheimers Dis. 2010, 2010, Article ID 587463.
-
(2010)
Int. J. Alzheimers Dis
-
-
Linnartz, B.1
Wang, Y.2
Neumann, H.3
-
17
-
-
75849151435
-
Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury
-
Lehnardt, S. Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury. Glia 2010, 5, 253-263.
-
(2010)
Glia
, vol.5
, pp. 253-263
-
-
Lehnardt, S.1
-
19
-
-
0036403097
-
Chronic brain inflammation results in cell loss in the entorhinal cortex and impaired LTP in perforant path-granule cell synapses
-
Hauss-Wegrzyniak, B.; Lynch, M.A.; Vraniak, P.D.; Wenk, G.L. Chronic brain inflammation results in cell loss in the entorhinal cortex and impaired LTP in perforant path-granule cell synapses. Exp. Neurol. 2002, 176, 336-341.
-
(2002)
Exp. Neurol
, vol.176
, pp. 336-341
-
-
Hauss-Wegrzyniak, B.1
Lynch, M.A.2
Vraniak, P.D.3
Wenk, G.L.4
-
20
-
-
33847759064
-
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
-
Qin, L.; Wu, X.; Block, M.L.; Liu, Y.; Breese, G.R.; Hong, J.S.; Knapp, D.J.; Crews, F.T. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 2007, 55, 453-462.
-
(2007)
Glia
, vol.55
, pp. 453-462
-
-
Qin, L.1
Wu, X.2
Block, M.L.3
Liu, Y.4
Breese, G.R.5
Hong, J.S.6
Knapp, D.J.7
Crews, F.T.8
-
21
-
-
67749143921
-
Observation of beta-sheet aggregation in a gas-phase tau-peptide dimer
-
Vaden, T.D.; Gowers, S.A.; Snoek, L.C. Observation of beta-sheet aggregation in a gas-phase tau-peptide dimer. J. Am. Chem. Soc. 2009, 131, 2472-2474.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 2472-2474
-
-
Vaden, T.D.1
Gowers, S.A.2
Snoek, L.C.3
-
22
-
-
77951975748
-
Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils
-
Ahmed, M.; Davis, J.; Aucoin, D.; Sato, T.; Ahuja, S.; Aimoto, S.; Elliott, J.I.; van Nostrand, W.E.; Smith, S.O. Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils. Nat. Struct. Mol. Biol. 2010, 17, 561-567.
-
(2010)
Nat. Struct. Mol. Biol
, vol.17
, pp. 561-567
-
-
Ahmed, M.1
Davis, J.2
Aucoin, D.3
Sato, T.4
Ahuja, S.5
Aimoto, S.6
Elliott, J.I.7
van Nostrand, W.E.8
Smith, S.O.9
-
23
-
-
77649156805
-
Beta-sheet constitution of prion proteins
-
Ji, H.F.; Zhang, H.Y. Beta-sheet constitution of prion proteins. Trends Biochem. Sci. 2010, 35, 129-134.
-
(2010)
Trends Biochem. Sci
, vol.35
, pp. 129-134
-
-
Ji, H.F.1
Zhang, H.Y.2
-
24
-
-
51749125627
-
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein
-
Heise, H.; Celej, M.S.; Becker, S.; Riedel, D.; Pelah, A.; Kumar, A.; Jovin, T.M.; Baldus, M. Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein. J. Mol. Biol. 2008, 380, 444-450.
-
(2008)
J. Mol. Biol
, vol.380
, pp. 444-450
-
-
Heise, H.1
Celej, M.S.2
Becker, S.3
Riedel, D.4
Pelah, A.5
Kumar, A.6
Jovin, T.M.7
Baldus, M.8
-
25
-
-
67649856863
-
Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
-
Nekooki-Machida, Y.; Kurosawa, M.; Nukina, N.; Ito, K.; Oda, T.; Tanaka, M. Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity. Proc. Nat. Acad. Sci. USA 2009, 106, 9679-9684.
-
(2009)
Proc. Nat. Acad. Sci. USA
, vol.106
, pp. 9679-9684
-
-
Nekooki-Machida, Y.1
Kurosawa, M.2
Nukina, N.3
Ito, K.4
Oda, T.5
Tanaka, M.6
-
26
-
-
17444390124
-
Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q
-
Veerhuis, R.; Boshuizen, R.S.; Morbin, M.; Mazzoleni, G.; Hoozemans, J.J.; Langedijk, J.P.; Tagliavini, F.; Langeveld, J.P.; Eikelenboom, P. Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q. Neurobiol. Dis. 2005, 19, 273-282.
-
(2005)
Neurobiol. Dis
, vol.19
, pp. 273-282
-
-
Veerhuis, R.1
Boshuizen, R.S.2
Morbin, M.3
Mazzoleni, G.4
Hoozemans, J.J.5
Langedijk, J.P.6
Tagliavini, F.7
Langeveld, J.P.8
Eikelenboom, P.9
-
27
-
-
35648936428
-
Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure
-
Darnell, G.; Orgel, J.P.; Pahl, R.; Meredith, S.C. Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure. J. Mol. Biol. 2007, 374, 688-704.
-
(2007)
J. Mol. Biol
, vol.374
, pp. 688-704
-
-
Darnell, G.1
Orgel, J.P.2
Pahl, R.3
Meredith, S.C.4
-
28
-
-
27744464859
-
The microglial "activation" continuum: From innate to adaptive responses
-
Town, T.; Nikolic, V.; Tan, J. The microglial "activation" continuum: From innate to adaptive responses. J. Neuroinflammation 2005, 2, 24.
-
(2005)
J. Neuroinflammation
, vol.2
, pp. 24
-
-
Town, T.1
Nikolic, V.2
Tan, J.3
-
29
-
-
33645235438
-
Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington's and Parkinson's diseases
-
Bodner, R.A.; Outeiro, T.F.; Altmann, S.; Maxwell, M.M.; Cho, S.H.; Hyman, B.T.; McLean, P.J.; Young, A.B.; Housman, D.E.; Kazantsev, A.G. Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington's and Parkinson's diseases. Proc. Nat. Acad. Sci. USA 2006, 103, 4246-4251.
-
(2006)
Proc. Nat. Acad. Sci. USA
, vol.103
, pp. 4246-4251
-
-
Bodner, R.A.1
Outeiro, T.F.2
Altmann, S.3
Maxwell, M.M.4
Cho, S.H.5
Hyman, B.T.6
McLean, P.J.7
Young, A.B.8
Housman, D.E.9
Kazantsev, A.G.10
-
30
-
-
79959826755
-
Microglial alterations in human Alzheimer's disease following Ab42 immunisation
-
doi: 10.1111/j.1365-2990.2010.01156.x. [Epub ahead of print]
-
Zotova, E.; Holmes, C; Johnston, D.; Neal, J.W.; Nicoll, J.A.; Boche, D. Microglial alterations in human Alzheimer's disease following Ab42 immunisation. Neuropathol. Appl. Neurobiol. 2010, doi: 10.1111/j.1365-2990.2010.01156.x. [Epub ahead of print].
-
(2010)
Neuropathol. Appl. Neurobiol
-
-
Zotova, E.1
Holmes, C.2
Johnston, D.3
Neal, J.W.4
Nicoll, J.A.5
Boche, D.6
-
31
-
-
70349518598
-
Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models
-
Sugama, S.; Takenouchi, T.; Cho, B.P.; Joh, T.H.; Hashimoto, M.; Kitani, H. Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models. Inflamm. Allergy Drug Targets 2009, 4, 277-284.
-
(2009)
Inflamm. Allergy Drug Targets
, vol.4
, pp. 277-284
-
-
Sugama, S.1
Takenouchi, T.2
Cho, B.P.3
Joh, T.H.4
Hashimoto, M.5
Kitani, H.6
-
32
-
-
34248392684
-
Microglial activation and its implications in the brain diseases
-
Dheen, S.T.; Kaur, C; Ling, E.A. Microglial activation and its implications in the brain diseases. Curr. Med. Chem. 2007, 14, 1189-1197.
-
(2007)
Curr. Med. Chem
, vol.14
, pp. 1189-1197
-
-
Dheen, S.T.1
Kaur, C.2
Ling, E.A.3
-
33
-
-
0036850023
-
Neuroinflammation in Alzheimer's disease and prion disease
-
Eikelenboom, P.; Bate, C, van Gool, W.A.; Hoozemans, J.J.; Rozemuller, J.M.; Veerhuis, R.; Williams, A. Neuroinflammation in Alzheimer's disease and prion disease. Glia 2002, 40, 232-239.
-
(2002)
Glia
, vol.40
, pp. 232-239
-
-
Eikelenboom, P.1
Bate, C.2
van Gool, W.A.3
Hoozemans, J.J.4
Rozemuller, J.M.5
Veerhuis, R.6
Williams, A.7
-
34
-
-
19944414648
-
Amyloid associated proteins in Alzheimer's and prion disease
-
Veerhuis, R.; Boshuizen, R.S.; Familian, A. Amyloid associated proteins in Alzheimer's and prion disease. Curr. Drug Targets CNS Neurol. Disord. 2005, 4, 235-248.
-
(2005)
Curr. Drug Targets CNS Neurol. Disord
, vol.4
, pp. 235-248
-
-
Veerhuis, R.1
Boshuizen, R.S.2
Familian, A.3
-
35
-
-
0036798415
-
Copper-dependent functions for the prion protein
-
Brown, D.R.; Sassoon, J. Copper-dependent functions for the prion protein. Mol. Biotechnol. 2002, 2, 165-178.
-
(2002)
Mol. Biotechnol
, vol.2
, pp. 165-178
-
-
Brown, D.R.1
Sassoon, J.2
-
36
-
-
0035145614
-
Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
-
Wong, B.S.; Liu, T.; Li, R.; Pan, T.; Petersen, R.B.; Smith, M.A.; Gambetti, P.; Perry, G; Manson, J.C.; Brown, D.R.; Sy, M.S. Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein. J. Neurochem. 2001, 76, 565-572.
-
(2001)
J. Neurochem
, vol.76
, pp. 565-572
-
-
Wong, B.S.1
Liu, T.2
Li, R.3
Pan, T.4
Petersen, R.B.5
Smith, M.A.6
Gambetti, P.7
Perry, G.8
Manson, J.C.9
Brown, D.R.10
Sy, M.S.11
-
37
-
-
33749147853
-
Translocation and potential neurological effects of fine and ultrafine particles a critical update
-
Peters, A.; Veronesi B.; Calderón-Garcidueñas, L.; Gehr, P.; Chen, L.C.; Geiser, M.; Reed, W.; Rothen-Rutishauser, B.; Schürch, S.; Schulz, H. Translocation and potential neurological effects of fine and ultrafine particles a critical update. Par. Fibre Toxicol. 2006, 8, 3-13.
-
(2006)
Par. Fibre Toxicol
, vol.8
, pp. 3-13
-
-
Peters, A.1
Veronesi, B.2
Calderón-Garcidueñas, L.3
Gehr, P.4
Chen, L.C.5
Geiser, M.6
Reed, W.7
Rothen-Rutishauser, B.8
Schürch, S.9
Schulz, H.10
-
38
-
-
71049126547
-
Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure
-
Antonini, J.M.; Sriram, K.; Benkovic, S.A.; Roberts, J.R.; Stone, S.; Chen, B.T.; Schwegler-Berry, D.; Jefferson, A.M.; Billig, B.K.; Felton, C.M. et al. Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure. Neurotoxicology 2009, 30, 915-925.
-
(2009)
Neurotoxicology
, vol.30
, pp. 915-925
-
-
Antonini, J.M.1
Sriram, K.2
Benkovic, S.A.3
Roberts, J.R.4
Stone, S.5
Chen, B.T.6
Schwegler-Berry, D.7
Jefferson, A.M.8
Billig, B.K.9
Felton, C.M.10
-
39
-
-
84855705820
-
Nanoparticles and the brain: Cause for concern
-
Oberdörster, G.; Elder, A.; Rinderknecht, A. Nanoparticles and the brain: Cause for concern? Trends Neurosci. 2009, 32, 506-516.
-
(2009)
Trends Neurosci
, vol.32
, pp. 506-516
-
-
Oberdörster, G.1
Elder, A.2
Rinderknecht, A.3
-
40
-
-
77955568951
-
Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain
-
van Berlo, D.; Albrecht, C.; Knaapen, A.M.; Cassee, F.R.; Gerlofs-Nijland, M.E.; Kooter, I.M.; Palomero-Gallagher, N.; Bidmon, H.J.; van Schooten, F.J.; Krutmann, J. et al. Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain. Arch. Toxicol. 2010, 84, 553-562.
-
(2010)
Arch Toxicol
, vol.84
, pp. 553-562
-
-
van Berlo, D.1
Albrecht, C.2
Knaapen, A.M.3
Cassee, F.R.4
Gerlofs-Nijland, M.E.5
Kooter, I.M.6
Palomero-Gallagher, N.7
Bidmon, H.J.8
van Schooten, F.J.9
Krutmann, J.10
-
41
-
-
7444238755
-
Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain
-
Campbell, A.; Oldham, M.; Becaria, A.; Bondy, S.C.; Meacher, D.; Sioutas, C.; Misra, C.; Mendez, L.B.; Kleinman, M. Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain. Neurotoxicology 2005, 26, 133-140.
-
(2005)
Neurotoxicology
, vol.26
, pp. 133-140
-
-
Campbell, A.1
Oldham, M.2
Becaria, A.3
Bondy, S.C.4
Meacher, D.5
Sioutas, C.6
Misra, C.7
Mendez, L.B.8
Kleinman, M.9
-
42
-
-
42649113710
-
Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways
-
Kleinman, M.T.; Araujo, J.A.; Nel, A.; Sioutas, C.; Campbell, A.; Cong, P.Q.; Li, H.; Bondy, S.C. Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicol. Lett. 2008, 178, 127-130.
-
(2008)
Toxicol. Lett
, vol.178
, pp. 127-130
-
-
Kleinman, M.T.1
Araujo, J.A.2
Nel, A.3
Sioutas, C.4
Campbell, A.5
Cong, P.Q.6
Li, H.7
Bondy, S.C.8
-
43
-
-
56049102066
-
Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles
-
Wang, J.; Liu, Y.; Jiao, F.; Lao, F.; Li, W.; Gu, Y.; Li, Y.; Ge, C.; Zhou, G.; Li, B.; Zhao, Y.; Chai, Z.; Chen, C. Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles. Toxicology 2008, 254, 82-90.
-
(2008)
Toxicology
, vol.254
, pp. 82-90
-
-
Wang, J.1
Liu, Y.2
Jiao, F.3
Lao, F.4
Li, W.5
Gu, Y.6
Li, Y.7
Ge, C.8
Zhou, G.9
Li, B.10
Zhao, Y.11
Chai, Z.12
Chen, C.13
-
44
-
-
71549145597
-
Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse
-
Shin, J.A.; Lee, E.J.; Seo, S.M.; Kim, H.S.; Kang, J.L.; Park, E.M. Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse. Neuroscience 2010, 165, 445-454.
-
(2010)
Neuroscience
, vol.165
, pp. 445-454
-
-
Shin, J.A.1
Lee, E.J.2
Seo, S.M.3
Kim, H.S.4
Kang, J.L.5
Park, E.M.6
-
45
-
-
37349050628
-
Changes in neurotransmitter levels and proinflammatory cytokine mRNA expressions in the mice olfactory bulb following nanoparticle exposure
-
Win-Shwe, T.T.; Mitsushima, D.; Yamamoto, S.; Fukushima, A.; Funabashi, T.; Kobayashi, T.; Fujimaki, H. Changes in neurotransmitter levels and proinflammatory cytokine mRNA expressions in the mice olfactory bulb following nanoparticle exposure. Toxicol. Appl. Pharmacol. 2008, 226, 192-198.
-
(2008)
Toxicol. Appl. Pharmacol
, vol.226
, pp. 192-198
-
-
Win-Shwe, T.T.1
Mitsushima, D.2
Yamamoto, S.3
Fukushima, A.4
Funabashi, T.5
Kobayashi, T.6
Fujimaki, H.7
-
46
-
-
77958459116
-
Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells
-
Trickler, W.J.; Lantz, S.M.; Murdock, R.C.; Schrand, A.M.; Robinson, B.L.; Newport, G.D.; Schlager, J.J.; Oldenburg, S.J.; Paule, M.G.; Slikker, W., Jr. et al. Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. Toxicol. Sci. 2010, 118, 160-170.
-
(2010)
Toxicol. Sci
, vol.118
, pp. 160-170
-
-
Trickler, W.J.1
Lantz, S.M.2
Murdock, R.C.3
Schrand, A.M.4
Robinson, B.L.5
Newport, G.D.6
Schlager, J.J.7
Oldenburg, S.J.8
Paule, M.G.9
Slikker, W.10
-
47
-
-
77957924085
-
Nanoparticles induce changes of the electrical activity of neuronal networks on microelectrode array neurochips
-
Gramowski, A.; Flossdorf, J.; Bhattacharya, K.; Jonas, L.; Lantow, M.; Rahman, Q.; Schiffmann, D.; Weiss, D.G.; Dopp, E. Nanoparticles induce changes of the electrical activity of neuronal networks on microelectrode array neurochips. Environ. Health Perspect. 2010, 118, 1363-1369.
-
(2010)
Environ. Health Perspect
, vol.118
, pp. 1363-1369
-
-
Gramowski, A.1
Flossdorf, J.2
Bhattacharya, K.3
Jonas, L.4
Lantow, M.5
Rahman, Q.6
Schiffmann, D.7
Weiss, D.G.8
Dopp, E.9
-
48
-
-
35048893279
-
3 particles into the brain: Micro-distribution, chemical states, and histopathological observation
-
Wang, B.; Feng, W.Y.; Wang, M.; Shi, J.W.; Zhang, F.; Ouyang, H.; Zhao, Y.L.; Chai, Z.F.; Huang, Y.Y.; Xie, Y.N. et al. Transport of intranasally instilled fine Fe2O3 particles into the brain: Micro-distribution, chemical states, and histopathological observation. Biol. Trace Elem. Res. 2007, 118, 233-243.
-
(2007)
Biol. Trace Elem. Res
, vol.118
, pp. 233-243
-
-
Wang, B.1
Feng, W.Y.2
Wang, M.3
Shi, J.W.4
Zhang, F.5
Ouyang, H.6
Zhao, Y.L.7
Chai, Z.F.8
Huang, Y.Y.9
Xie, Y.N.10
-
49
-
-
0037066398
-
Pro-inflammatory effects of aluminum in human glioblastoma cells
-
Campbell, A.; Yang, Y.; Tsai-Turton, M.; Bondy, S.C. Pro-inflammatory effects of aluminum in human glioblastoma cells. Brain Res. 2002, 933, 62-65.
-
(2002)
Brain Res
, vol.933
, pp. 62-65
-
-
Campbell, A.1
Yang, Y.2
Tsai-Turton, M.3
Bondy, S.C.4
-
50
-
-
68249139284
-
Particulate matter induced enhancement of inflammatory markers in the brains of apolipoprotein E knockout mice
-
Campbell, A.; Araujo, J.A.; Li, H.; Sioutas, C.; Kleinman, M. Particulate matter induced enhancement of inflammatory markers in the brains of apolipoprotein E knockout mice. Nanosci. Nanotechnol. 2009, 9, 5099-5104.
-
(2009)
Nanosci. Nanotechnol
, vol.9
, pp. 5099-5104
-
-
Campbell, A.1
Araujo, J.A.2
Li, H.3
Sioutas, C.4
Kleinman, M.5
-
51
-
-
77956224961
-
The neurotoxicity of environmental aluminum is still an issue
-
Bondy, S.C. The neurotoxicity of environmental aluminum is still an issue. Neurotoxicology 2010, 31, 575-581.
-
(2010)
Neurotoxicology
, vol.31
, pp. 575-581
-
-
Bondy, S.C.1
-
52
-
-
0742322782
-
Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain
-
Campbell, A.; Becaria, A.; Lahiri, D.K.; Sharman, K.; Bondy, S.C. Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain. J. Neurosci. Res. 2004, 75, 565-672.
-
(2004)
J. Neurosci. Res
, vol.75
, pp. 565-672
-
-
Campbell, A.1
Becaria, A.2
Lahiri, D.K.3
Sharman, K.4
Bondy, S.C.5
-
53
-
-
33746034583
-
Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain
-
Becaria, A.; Lahiri, D.; Bondy, S.C; Chen, D.; Hamadeh, A.; Li, H.; Taylor, R.; Campbell, A. Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain. J. Neuroimmunol. 2006, 176, 16-23.
-
(2006)
J. Neuroimmunol
, vol.176
, pp. 16-23
-
-
Becaria, A.1
Lahiri, D.2
Bondy, S.C.3
Chen, D.4
Hamadeh, A.5
Li, H.6
Taylor, R.7
Campbell, A.8
-
54
-
-
0026244799
-
Systemic macrophage stimulation in rats with silicosis: Enhanced release of tumor necrosis factor-alpha from alveolar and peritoneal macrophages
-
Mohr, C; Gemsa, D.; Graebner, C; Hemenway, D.R.; Leslie, K.O.; Absher, P.M.; Davis, G.S. Systemic macrophage stimulation in rats with silicosis: Enhanced release of tumor necrosis factor-alpha from alveolar and peritoneal macrophages. Am. J. Respir. Cell. Mol. Biol. 1991, 5, 395-402.
-
(1991)
Am. J. Respir. Cell. Mol. Biol
, vol.5
, pp. 395-402
-
-
Mohr, C.1
Gemsa, D.2
Graebner, C.3
Hemenway, D.R.4
Leslie, K.O.5
Absher, P.M.6
Davis, G.S.7
-
55
-
-
63349095579
-
A novel approach to the identification and quantitative elemental analysis of amyloid deposits-insights into the pathology of Alzheimer's disease
-
Rajendran, R.; Minqin, R.; Ynsa, M.D.; Casadesus, G; Smith, M.A.; Perry, G; Halliwell, B.; Watt, F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits-insights into the pathology of Alzheimer's disease. Biochem. Biophys. Res. Commun. 2009, 382, 91-95.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.382
, pp. 91-95
-
-
Rajendran, R.1
Minqin, R.2
Ynsa, M.D.3
Casadesus, G.4
Smith, M.A.5
Perry, G.6
Halliwell, B.7
Watt, F.8
-
56
-
-
0029917146
-
The promotion of iron-induced generation of reactive oxygen species in nerve tissue by aluminum
-
Bondy, S.C; Kirstein, S. The promotion of iron-induced generation of reactive oxygen species in nerve tissue by aluminum. Mol. Chem. Neuropathol. 1996, 27, 185-194.
-
(1996)
Mol. Chem. Neuropathol
, vol.27
, pp. 185-194
-
-
Bondy, S.C.1
Kirstein, S.2
-
57
-
-
0032514165
-
Promotion of transition metal-induced production of reactive oxygen species formation by β-amyloid
-
Bondy, S.C; Guo-Ross, S.X.; Truong, A.T. Promotion of transition metal-induced production of reactive oxygen species formation by β-amyloid. Brain Res. 1998, 799, 91-96.
-
(1998)
Brain Res
, vol.799
, pp. 91-96
-
-
Bondy, S.C.1
Guo-Ross, S.X.2
Truong, A.T.3
-
58
-
-
0031912255
-
Mechanisms underlying aluminum-induced potentiation of oxidant properties of transition metals
-
Bondy, S.C; Guo-Ross, S.X.; Pien, J. Mechanisms underlying aluminum-induced potentiation of oxidant properties of transition metals. Neurotoxicology 1998b, 19, 65-72.
-
(1998)
Neurotoxicology
, vol.19
, pp. 65-72
-
-
Bondy, S.C.1
Guo-Ross, S.X.2
Pien, J.3
-
59
-
-
77956225539
-
The stabilization of ferrous iron by a toxic β-amyloid fragment and by an aluminum salt
-
Yang, E.Y.; Guo-Ross, S.X.; Bondy, S.C. The stabilization of ferrous iron by a toxic β-amyloid fragment and by an aluminum salt. Brain Res. 1999, 799, 91-96.
-
(1999)
Brain Res
, vol.799
, pp. 91-96
-
-
Yang, E.Y.1
Guo-Ross, S.X.2
Bondy, S.C.3
-
60
-
-
0035756816
-
The chemistry of transition metals in relation to their potential role in neurodegenerative processes
-
HaMai, D.; Bondy, S.C; Becaria, V.; Campbell, A. The chemistry of transition metals in relation to their potential role in neurodegenerative processes. Curr. Top. Med. Chem. 2001, 1, 541-551.
-
(2001)
Curr. Top. Med. Chem
, vol.1
, pp. 541-551
-
-
Hamai, D.1
Bondy, S.C.2
Becaria, V.3
Campbell, A.4
-
61
-
-
1842556556
-
Oxidative basis of manganese neurotoxicity
-
Bondy, S.C; HaMai, D. Oxidative basis of manganese neurotoxicity. Ann. N. Y. Acad. Sci. 2004, 1012, 129-141.
-
(2004)
Ann. N. Y. Acad. Sci
, vol.1012
, pp. 129-141
-
-
Bondy, S.C.1
Hamai, D.2
-
62
-
-
78650982804
-
Surface-mediated production of hydroxyl radicals as a mechanism of iron oxide nanoparticle biotoxicity
-
Voinov, M.A.; Pagán, J.O.; Morrison, E.; Smirnova, T.I.; Smirnov, A.I. Surface-mediated production of hydroxyl radicals as a mechanism of iron oxide nanoparticle biotoxicity J. Am. Chem. Soc. 2011, 133, 35-41.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 35-41
-
-
Voinov, M.A.1
Pagán, J.O.2
Morrison, E.3
Smirnova, T.I.4
Smirnov, A.I.5
-
63
-
-
2442656662
-
Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis
-
Panduri, V.; Weitzman, S.A.; Chandel, N.S.; Kamp, D.W. Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 2004, 286, L1220-L1227.
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.286
-
-
Panduri, V.1
Weitzman, S.A.2
Chandel, N.S.3
Kamp, D.W.4
-
64
-
-
34547147090
-
The redox chemistry of the Alzheimer's disease amyloid beta peptide
-
Smith, D.G.; Cappai, R.; Barnham, K.J. The redox chemistry of the Alzheimer's disease amyloid beta peptide. Biochim. Biophys. Acta 2007, 1768, 1976-1990.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 1976-1990
-
-
Smith, D.G.1
Cappai, R.2
Barnham, K.J.3
-
65
-
-
33751107948
-
Aluminium and iron, but neither copper nor zinc, are key to the precipitation of β-sheets of Aβ42 in senile plaque cores in Alzheimer's disease
-
Exley, C.J. Aluminium and iron, but neither copper nor zinc, are key to the precipitation of β-sheets of Aβ42 in senile plaque cores in Alzheimer's disease. J. Alzheim. Dis. 2006, 10, 173-177.
-
(2006)
J. Alzheim. Dis
, vol.10
, pp. 173-177
-
-
Exley, C.J.1
-
66
-
-
77956072590
-
Metalloproteomics and metal toxicology of α-synuclein
-
Santner, A.; Uversky, V.N. Metalloproteomics and metal toxicology of α-synuclein. Metallomics 2010, 2, 378-392.
-
(2010)
Metallomics
, vol.2
, pp. 378-392
-
-
Santner, A.1
Uversky, V.N.2
-
67
-
-
77049088538
-
Risks of copper and iron toxicity during aging in humans
-
Brewer, G.J. Risks of copper and iron toxicity during aging in humans. Chem. Res. Toxicol. 2010, 23, 319-326.
-
(2010)
Chem. Res. Toxicol
, vol.23
, pp. 319-326
-
-
Brewer, G.J.1
-
68
-
-
67649803877
-
Chelation therapy for neurodegenerative diseases
-
Bolognin, S.; Drago, D.; Messori, L.; Zatta, P. Chelation therapy for neurodegenerative diseases. Med. Res. Rev. 2009, 29, 547-570.
-
(2009)
Med. Res. Rev
, vol.29
, pp. 547-570
-
-
Bolognin, S.1
Drago, D.2
Messori, L.3
Zatta, P.4
-
69
-
-
77956218282
-
Mitochondrial iron metabolism and its role in neurodegeneration
-
Horowitz, M.P.; Greenamyre, J.T. Mitochondrial iron metabolism and its role in neurodegeneration. J. Alzheim. Dis. 2010, 20 (Suppl 2), S551-S568.
-
(2010)
J. Alzheim. Dis
, vol.20
, Issue.SUPPL. 2
-
-
Horowitz, M.P.1
Greenamyre, J.T.2
-
70
-
-
79954615141
-
Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism
-
Yang, G.; Meng, Y.; Li, W.; Yong, Y.; Fan, Z.; Ding, H.; Wei, Y.; Luo, J.; Ke, Z.J. Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism. Brain Pathol. 2011, 21, 279-297.
-
(2011)
Brain Pathol
, vol.21
, pp. 279-297
-
-
Yang, G.1
Meng, Y.2
Li, W.3
Yong, Y.4
Fan, Z.5
Ding, H.6
Wei, Y.7
Luo, J.8
Ke, Z.J.9
-
71
-
-
77955090824
-
Ion channels in monocytes and microglia/brain macrophages: Promising therapeutic targets for neurological diseases
-
Eder, C. Ion channels in monocytes and microglia/brain macrophages: Promising therapeutic targets for neurological diseases. J. Neuroimmunol. 2010, 224, 51-55.
-
(2010)
J. Neuroimmunol
, vol.224
, pp. 51-55
-
-
Eder, C.1
-
72
-
-
56449125770
-
Enhanced formation of oxidants from bimetallic nickel-iron nanoparticles in the presence of oxygen
-
Lee, C.; Sedlak, D.L. Enhanced formation of oxidants from bimetallic nickel-iron nanoparticles in the presence of oxygen. Environ. Sci. Technol. 2008, 42, 8528-8533.
-
(2008)
Environ. Sci. Technol
, vol.42
, pp. 8528-8533
-
-
Lee, C.1
Sedlak, D.L.2
-
73
-
-
55449132870
-
Characteristics and modifying factors of asbestos-induced oxidative DNA damage
-
Jiang, L.; Nagai, H.; Ohara, H.; Hara, S.; Tachibana, M.; Hirano, S.; Shinohara, Y.; Kohyama, N.; Akatsuka, S.; Toyokuni, S. Characteristics and modifying factors of asbestos-induced oxidative DNA damage. Cancer Sci. 2008, 99, 2142-2151.
-
(2008)
Cancer Sci
, vol.99
, pp. 2142-2151
-
-
Jiang, L.1
Nagai, H.2
Ohara, H.3
Hara, S.4
Tachibana, M.5
Hirano, S.6
Shinohara, Y.7
Kohyama, N.8
Akatsuka, S.9
Toyokuni, S.10
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