Semi-solid sucrose stearate-based emulsions as dermal drug delivery systems

Pharmaceutics

Volumn 3, Issue 2, 2011, Pages 275-306

  Klang, Victoria ^a   Schwarz, Julia C ^a   Matsko, Nadejda ^b   Rezvani, Elham ^c   El Hagin, Nivine ^a   Wirth, Michael ^a   Valenta, Claudia ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

Nanoemulsion; O W emulsion; Particle size; Semi solid; Skin penetration; Sucrose stearate s 970

Indexed keywords

CURCUMIN; DICLOFENAC; EMULSIFYING AGENT; FLUFENAMIC ACID; SUCROSE STEARATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DERMAL DRUG DELIVERY SYSTEM; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; EMULSION; HYDROPHILICITY; MACROEMULSION; NANOEMULSION; NONHUMAN; PARTICLE SIZE; SKIN PENETRATION; TEST STRIP; VISCOSITY;

EID: 79959846009     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics3020275     Document Type: Article

References (61)

1. Desai, N.B. Sucrose esters - an interesting class of substances for cosmetics. Parfuemerie Kosmet. 1985, 66, 629-632.
2. Thevenin, M.A.; Grossiord, J.L.; Poelman, M.C. Sucrose esters/cosurfactant microemulsion systems for transdermal delivery: Assessment of bicontinuous structures. Int. J. Pharm. 1996, 137, 177-186.
3. Hill, K.; Rhode, O. Sugar-based surfactants for consumer products and technical applications. Fett/Lipid 1999, 101, 25-33.
4. Carlotti, M.E.; Sapino, S.; Ugazio, E.; Peira, E.; Gallarate, M. O/W Moisturizing Emulsions with Saccharose Palmitate and Saccharose Stearate. J. Disp. Sci. Technol. 2008, 29, 375-386.
5. Takegami, S.; Kitamura, K.; Kawada, H.; Matsumoto, Y.; Kitade, T.; Ishida, H.; Nagata, C. Preparation and characterization of a new lipid nano-emulsion containing two cosurfactants, sodium palmitate for droplet size reduction and sucrose palmitate for stability enhancement. Chem. Pharm. Bull. (Tokyo) 2008, 56, 1097-1102.
6. Klang, V.; Matsko, N.; Zimmermann, A.M.; Vojnikovic, E.; Valenta, C. Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsions. Int. J. Pharm. 2010, 393, 152-160.
7. Klang, V.; Matsko, N.; Raupach, K.; El-Hagin, N.; Valenta, C. Development of sucrose stearate-based nanoemulsions and optimisation through gamma-cyclodextrin. Eur. J. Pharm. Biopharm. 2011, in press.
8. Calderilla-Fajardo, S.B.; Cazares-Delgadillo, J.; Villalobos-Garcia, R.; Quintanar-Guerrero, D.; Ganem-Quintanar, A.; Robles, R. Influence of sucrose esters on the in vivo percutaneous penetration of octyl methoxycinnamate formulated in nanocapsules, nanoemulsion, and emulsion. Drug Dev. Ind. Pharm. 2006, 32, 107-113.
9. Cazares-Delgadillo, J.; Naik, A.; Kalia, Y.N.; Quintanar-Guerrero, D.; Ganem-Quintanar, A. Skin permeation enhancement by sucrose esters: A pH-dependent phenomenon. Int. J. Pharm. 2005, 297, 204-212.
10. Csoka, G.; Marton, S.; Zelko, R.; Otomo, N.; Antal, I. Application of sucrose fatty acid esters in transdermal therapeutic systems. Eur. J. Pharm. Biopharm. 2007, 65, 233-237.
11. Szuts, A.; Budai-Szucs, M.; Eros, I.; Ambrus, R.; Otomo, N.; Szabo-Revesz, P. Study of thermo-sensitive gel-forming properties of sucrose stearates. J. Excipients Food Chem. 2010, 1, 13-20.
12. Gallegos, C.; Calahorro, C.; Munoz, J.; Berjano, M.; Guerrero, A. High-HLB sucrose esters: A peculiar viscous behaviour. Comun. Jorn. Com. Esp. Deterg. 1991, 22, 283-295.
13. Calahorro, C.; Munoz, J.; Berjano, M.; Guerrero, A.; Gallegos, C. Flow behavior of sucrose stearate/water systems. J. Am. Oil Chem. Soc. 1992, 69, 660-666.
14. Szuts, A.; Budai-Szucs, M.; Eros, I.; Otomo, N.; Szabo-Revesz, P. Study of gel-forming properties of sucrose esters for thermosensitive drug delivery systems. Int. J. Pharm. 2010, 383, 132-137.
15. Ullrich, S.; Metz, H.; Maeder, K. Sucrose ester nanodispersions: Microviscosity and viscoelastic properties. Eur. J. Pharm. Biopharm. 2008, 70, 550-555.
16. Mishra, P.R.; Al Shaal, L.; Mueller, R.H.; Keck, C.M. Production and characterization of Hesperetin nanosuspensions for dermal delivery. Int. J. Pharm. 2009, 371, 182-189.
17. Lee, S.J.; Choi, S.J.; Li, Y.; Decker, E.A.; McClements, D.J. Protein-stabilized nanoemulsions and emulsions: Comparison of physicochemical stability, lipid oxidation, and lipase digestibility. J. Agr. Food Chem. 2011, 59, 415-427.
18. Yilmaz, E.; Borchert, H.H. Design of a phytosphingosine-containing, positively-charged nanoemulsion as a colloidal carrier system for dermal application of ceramides. Eur. J. Pharm. Biopharm. 2005, 60, 91-98.
19. Saupe, A.; Gordon, K.C.; Rades, T. Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy. Int. J. Pharm. 2006, 314, 56-62.
20. Mueller, R.H. Zetapotential und Partikelladung in der Laborpraxis; Wissenschaftliche Verlagsgesellschaft mbH: Stuttgart, Germany, 1996; Band 37, Paperback APV.
21. Wabel, C. Influence of Lecithin on Structure and Stability of Parenteral Fat Emulsions, PhD Thesis; Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany, 1998.
22. Schalbart, P.; Kawaji, M.; Fumoto, K. Formation of tetradecane nanoemulsion by low-energy emulsification methods. Int. J. Refr. 2010, 33, 1612-1624.
23. Rao, M.A. Rheology of Fluid and Semisolid Foods: Principles and Applications; Aspen Publishers Inc.: Gaithersburg, MD, USA, 1999.
24. Taherian, A.R.; Fustier, P.; Ramaswamy, H.S. Effect of added oil and modified starch on rheological properties, droplet size distribution, opacity and stability of beverage cloud emulsions. J. Food Eng. 2006, 77, 687-696.
25. Valenta, C.; Kast, C.E.; Harich, I.; Bernkop-Schnuerch, A. Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone. J. Control. Release 2001, 77, 323-332.
26. Valenta, C.; Schultz, K. Influence of carrageenan on the rheology and skin permeation of microemulsion formulations. J. Control. Release 2004, 95, 257-265.
27. Klang, S.H.; Baszkinb, A.; Benita, S. The stability of piroxicam incorporated in a positively-charged submicron emulsion for ocular administration. Int. J. Pharm. 1996, 132, 33-44.
28. Michniak-Kohn, B.B.; Wertz, P.W.; Al-Khalili, M.; Meidan, V.M. Skin: Physiology and Penetration Pathways. In Delivery System Handbook for Personal Care and Cosmetic Products; Rosen, M.R., Ed.; William Andrew Inc.: New York, NY, USA, 2005; pp. 77-100.
29. Hoeller, S.; Valenta, C. Effect of selected fluorinated drugs in a ringing gel on rheological behaviour and skin permeation. Eur. J. Pharm. Biopharm. 2007, 66, 120-126.
30. Lin, C.; Lin, H.; Chenc, H.; Yu, M.; Lee, M. Stability and characterisation of phospholipid-based curcumin-encapsulated microemulsions. Food Chem. 2009, 116, 923-928.
31. Maiti, K.; Mukherjee, K.; Gantait, A.; Saha, B.P.; Mukherjee, P.K. Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats. Int. J. Pharm. 2007, 330, 155-163.
32. Hahn, T.; Hansen, S.; Neumann, D.; Kostka, K.H.; Lehr, C.M.; Muys, L.; Schaefer, U.F. Infrared densitometry: A fast and non-destructive method for exact stratum corneum depth calculation for in vitro tape-stripping. Skin Pharmacol. Physiol. 2010, 23, 183-192.
33. Klang, V.; Schwarz, J.C.; Hartl, A.; Valenta, C. Facilitating in vitro tape stripping: Application of infrared densitometry for quantification of porcine stratum corneum proteins. Skin Pharmacol. Physiol. 2011, in press.
34. Breternitz, M.; Flach, M.; Prassler, J.; Elsner, P.; Fluhr, J.W. Acute barrier disruption by adhesive tapes is influenced by pressure, time and anatomical location: Integrity and cohesion assessed by sequential tape stripping. A randomized, controlled study. Br. J. Dermatol. 2007, 156, 231-240.
35. Lademann, J.; Jacobi, U.; Surber, C.; Weigmann, H.J.; Fluhr, J.W. The tape stripping procedure--evaluation of some critical parameters. Eur. J. Pharm. Biopharm. 2009, 72, 317-323.
36. Voegeli, R.; Heiland, J.; Doppler, S.; Rawlings, A.V.; Schreier, T. Efficient and simple quantification of stratum corneum proteins on tape strippings by infrared densitometry. Skin Res. Technol. 2007, 13, 242-251.
37. Hanyšová, L.; Mokrý, M.; Kastner, P.; Klimeš, J. HPLC Evaluation of Diclofenac in the Various Forms of Therapeutic Preparations. Chem. Pap. 2005, 59, 103-108.
38. Rao, J.; McClements, D.J. Stabilization of phase inversion temperature nanoemulsions by surfactant displacement. J. Agr. Food Chem. 2010, 58, 7059-7066.
39. Benita, S.; Levy, M.Y. Submicron emulsions as colloidal drug carriers for intravenous administration: Comprehensive physicochemical characterization. J. Pharm. Sci. 1993, 82, 1069-1079.
40. Sznitowska, M.; Janicki, S.; Dabrowska, E.; Zurowska-Pryczkowska, K. Submicron emulsions as drug carriers. Studies on destabilization potential of various drugs. Eur. J. Pharm. Sci. 2001, 12, 175-179.
41. Jahanzad, F.; Josephides, J.; Mansourian, A.; Sajjadi, S. Dynamics of Transitional Phase Inversion Emulsification: Effect of Addition Time on the Type of Inversion and Drop Size. Ind. Eng. Chem. Res. 2010, 49, 7631-7637.
42. Keck, C.M.; Mueller, R.H. Size analysis of submicron particles by laser diffractometry--90% of the published measurements are false. Int. J. Pharm. 2008, 355, 150-163.
43. Gradzielski, M.; Bergmeier, M.; Mueller, M.; Hoffmann, H. Novel Gel Phase: A Cubic Phase of Densely Packed Monodisperse, Unilamellar Vesicles. J. Phys. Chem. B 1997, 101, 1719-1722.
44. Gradzielski, M.; Mueller, M.; Bergmeier, M.; Hoffmann, H.; Hoinkis, E. Structural and Macroscopic Characterization of a Gel Phase of Densely Packed Monodisperse, Unilamellar Vesicles. J. Phys. Chem. B 1999, 103, 1416-1424.
45. Kawada, H.; Kume, T.; Matsunaga, T.; Iwai, H.; Sano, T.; Shibayama, M. Structure and Rheology of a Self-Standing Nanoemulsion. Langmuir 2009, 26, 2430-2437.
46. Sadtler, V.M.; Guely, M.; Marchal, P.; Choplin, L. Shear-induced phase transitions in sucrose ester surfactant. J. Colloid. Interface Sci. 2004, 270, 270-275.
47. Savic, S.D.; Savic, M.M.; Vesic, S.A.; Vuleta, G.M.; Mueller-Goymann, C.C. Vehicles based on a sugar surfactant: Colloidal structure and its impact on in vitro/in vivo hydrocortisone permeation. Int. J. Pharm. 2006, 320, 86-95.
48. Mason, T.G.; Graves, S.M.; Wilking, J.N.; Lin, M.Y. Extreme emulsification: Formation and structure of nanoemulsions. Condens. Matter Phys. 2006, 1, 193-199.
49. Graves, S.; Meleson, K.; Wilking, J.; Lin, M.Y.; Mason, T.G. Structure of concentrated nanoemulsions. J. Chem. Phys. 2005, 122, 134703-1-134703-16.
50. Cortés-Muñoz, M.; Chevalier-Lucia, D.; Dumay, E. Characteristics of submicron emulsions prepared by ultra-high pressure homogenisation: Effect of chilled or frozen storage. Food Hydrocolloid. 2009, 23, 640-654.
51. Tadros, T.; Izquierdo, P.; Esquena, J.; Solans, C. Formation and stability of nano-emulsions. Adv. Colloid Interface Sci. 2004, 108-109, 303-318.
52. Heuschkel, S. Untersuchungen zum Mechanismus der Penetrationserhöhung durch Mikroemulsionen und neue Enhancer bei der dermalen Applikation von Wirkstoffen, PhD Thesis; Martin-Luther-University, Halle-Wittenberg, Germany, 2009.
53. McClements, D.J. Food Emulsions: Principles, Practices, and Techniques; CRC Press: Boca Raton, FL, USA, 2005.
54. Valdez, M.A.; Acedo-Carrillo, J.I.; Rosas-Durazo, A.; Lizardi, J.; Rinaudo, M.; Goycoolea, F.M. Small-deformation rheology of mesquite gum stabilized oil in water emulsions. Carbohyd. Polym. 2006, 64, 205-211.
55. Mason, T.G.; Graves, S.M.; Wilking, J.N.; Lin, M.Y. Effective structure factor of osmotically deformed nanoemulsions. J. Phys. Chem. B 2006, 110, 22097-22102.
56. Lee, C.H.; Moturi, V.; Lee, Y. Thixotropic property in pharmaceutical formulations. J. Control. Release 2009, 136, 88-98.
57. Friedman, D.I.; Schwarz, J.S.; Weisspapir, M. Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal antiinflammatory drugs. J. Pharm. Sci. 1995, 84, 324-329.
58. Bouchemal, K.; Briancon, S.; Perrier, E.; Fessi, H. Nanoemulsion formulation using spontaneous emulsification: Solvent, oil and surfactant optimisation. Int. J. Pharm. 2004, 280, 241-251.
59. Wu, X.; Biatry, B.; Cazeneuve, C.; Guy, R.H. Drug delivery to the skin from sub-micron polymeric particle formulations: Influence of particle size and polymer hydrophobicity. Pharm. Res. 2009, 26, 1995-2001.
60. Wagner, H.; Kostka, K.H.; Lehr, C.M.; Schaefer, U.F. Drug distribution in human skin using two different in vitro test systems: Comparison with in vivo data. Pharm. Res. 2000, 17, 1475-1481.
61. Stracke, F.; Weiss, B.; Lehr, C.M.; Koenig, K.; Schaefer, U.F.; Schneider, M. Multiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs. J. Invest. Dermatol. 2006, 126, 2224-2233.