Development of sucrose stearate-based nanoemulsions and optimisation through γ-cyclodextrin

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 1, 2011, Pages 58-67

  Klang, Victoria ^a   Matsko, Nadejda ^b   Raupach, Karoline ^a   El Hagin, Nivine ^a   Valenta, Claudia ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Cyclodextrin; Cryo TEM; Fludrocortisone acetate; Lecithin; Nanoemulsion; Sucrose stearate

Indexed keywords

ESTER; FLUCONAZOLE; FLUDROCORTISONE ACETATE; FLUFENAMIC ACID; GAMMA CYCLODEXTRIN; MINOXIDIL; PHOSPHATIDYLCHOLINE; SORBATE POTASSIUM; STEARIC ACID; SUCROSE; SUCROSE STEARATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; DISPERSION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; ELECTRIC CONDUCTIVITY; FILM; LIPOPHILICITY; MOLECULAR STABILITY; NANOEMULSION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; SKIN PERMEABILITY; SWINE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ABDOMEN; ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLODEXTRINS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; EMULSIONS; EXCIPIENTS; FLUDROCORTISONE; GAMMA-CYCLODEXTRINS; MODELS, CHEMICAL; NANOPARTICLES; PARTICLE SIZE; PERMEABILITY; SKIN; SKIN ABSORPTION; SOLUBILITY; SUCROSE; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS; SWINE;

EID: 79959854158     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.01.010     Document Type: Article

References (51)

1. Y. Baspinar, Nano- and microemulsions for topical application of poorly soluble immunosuppressives, PhD Thesis, Free University Berlin, 2009.
2. R. Daniels, Galenic principles of modern skin care products, Skin Care Forum Online Issue 25, Society for Dermopharmacy, 2001. < http://www.scf-online.com/english/25-e/galenic-25-e.htm >.
3. V.B. Patravale, and S.D. Mandawgade Novel cosmetic delivery systems: an application update Int. J. Cosmet. Sci. 30 2008 19 33
4. Y.A. Shchipunov Self-organising structures of lecithin Russ. Chem. Rev. 66 1997 301 322 (Pubitemid 128002846)
5. L. Rydhag, and I. Wilton The function of phospholipids of soybean lecithin in emulsions J. Am. Oil Chem. Soc. 58 1981 830 837 (Pubitemid 12505503)
6. C. Wabel, Influence of Lecithin on Structure and Stability of Parenteral Fat Emulsions, PhD Thesis, Friedrich-Alexander-Universität Erlangen-Nürnberg, 1998.
7. T.P. Norden, B. Siekmann, S. Lundquist, and M. Malmsten Physicochemical characterisation of a drug-containing phospholipid-stabilised o/w emulsion for intravenous administration Eur. J. Pharm. Sci. 13 2001 393 401 (Pubitemid 32618647)
8. X. Liu, Y. Zhang, X. Tang, and H. Zhang Determination of entrapment efficiency and drug phase distribution of submicron emulsions loaded silybin J. Microencapsul. 26 2009 180 186
9. D. Watrobska-Swietlikowska, and M. Sznitowska Partitioning of parabens between phases of submicron emulsions stabilized with egg lecithin Int. J. Pharm. 312 2006 174 178
10. J. Han, and C. Washington Partition of antimicrobial additives in an intravenous emulsion and their effect on emulsion physical stability Int. J. Pharm. 288 2005 263 271 (Pubitemid 40038579)
11. J.J. Wang, K.C. Sung, O.Y. Hu, C.H. Yeh, and J.Y. Fang Submicron lipid emulsion as a drug delivery system for nalbuphine and its prodrugs J. Control. Release 115 2006 140 149 (Pubitemid 44559707)
12. M. Krafft, J. Rolland, and J.G. Riess Detrimental effect of excess lecithin on the stability of fluorocarbon/lecithin emulsions J. Phys. Chem. 95 1991 5673 5676
13. T. Tadros, P. Izquierdo, J. Esquena, and C. Solans Formation and stability of nano-emulsions Adv. Colloid Interface Sci. 108-109 2004 303 318
14. S.C. Yang, and S. Benita Enhanced absorption and drug targeting by positively charged submicron emulsions Drug Dev. Res. 50 2000 476 486
15. J.V. Henry, P.J. Fryer, W.J. Frith, and I.T. Norton Emulsification mechanism and storage instabilities of hydrocarbon-in-water sub-micron emulsions stabilised with Tweens (20 and 80), Brij 96v and sucrose monoesters J. Colloid Interface Sci. 338 2009 201 206
16. P.C. Calder, G.L. Jensen, B.V. Koletzko, P. Singer, and G.J. Wanten Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions Intensive Care Med. 36 2010 735 749
17. S. Hoeller, A. Sperger, and C. Valenta Lecithin based nanoemulsions: a comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation Int. J. Pharm. 370 2009 181 186
18. S.B. Calderilla-Fajardo, J. Cazares-Delgadillo, R. Villalobos-Garcia, D. Quintanar-Guerrero, A. Ganem-Quintanar, and R. Robles Influence of sucrose esters on the in vivo percutaneous penetration of octyl methoxycinnamate formulated in nanocapsules, nanoemulsion, and emulsion Drug Dev. Ind. Pharm. 32 2006 107 113 (Pubitemid 43220919)
19. S. Takegami, K. Kitamura, H. Kawada, Y. Matsumoto, T. Kitade, H. Ishida, and C. Nagata Preparation and characterization of a new lipid nano-emulsion containing two cosurfactants, sodium palmitate for droplet size reduction and sucrose palmitate for stability enhancement Chem. Pharm. Bull. (Tokyo) 56 2008 1097 1102
20. V. Klang, N. Matsko, A.M. Zimmermann, E. Vojnikovic, and C. Valenta Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsions Int. J. Pharm. 393 2010 152 160
21. S. Hoeller, and C. Valenta Effect of selected fluorinated drugs in a "ringing" gel on rheological behaviour and skin permeation Eur. J. Pharm. Biopharm. 66 2007 120 126 (Pubitemid 46412963)
22. A. Hasanovic, C. Hollick, K. Fischinger, and C. Valenta Improvement in physicochemical parameters of DPPC liposomes and increase in skin permeation of aciclovir and minoxidil by the addition of cationic polymers Eur. J. Pharm. Biopharm. 75 2010 148 153
23. E. Yilmaz, and H.H. Borchert Design of a phytosphingosine-containing, positively-charged nanoemulsion as a colloidal carrier system for dermal application of ceramides Eur. J. Pharm. Biopharm. 60 2005 91 98 (Pubitemid 40545865)
24. R.H. Mueller, Zetapotential und Partikelladung in der Laborpraxis, Band 37, Paperback APV, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 1996.
25. J. Cazares-Delgadillo, A. Naik, Y.N. Kalia, D. Quintanar-Guerrero, and A. Ganem-Quintanar Skin permeation enhancement by sucrose esters: a pH-dependent phenomenon Int. J. Pharm. 297 2005 204 212 (Pubitemid 40723638)
26. B.B. Michniak-Kohn, P.W. Wertz, M. Al-Khalili, V.M. Meidan, Skin: physiology and penetration pathways, in: M.R. Rosen (Ed.), Delivery System Handbook for Personal Care and Cosmetic Products, Springer, Berlin, 2005, pp. 77-100.
27. S. Cisternino, J. Schlatter, and J.L. Saulnier Stability of fludrocortisone acetate solutions prepared from tablets and powder Eur. J. Pharm. Biopharm. 55 2003 209 213 (Pubitemid 36299220)
28. B. Lundberg Preparation of drug-carrier emulsions stabilized with phosphatidylcholine-surfactant mixtures J. Pharm. Sci. 83 1994 72 75 (Pubitemid 24233734)
29. T.G. Mason, J.N. Wilking, K. Meleson, C.B. Chang, and S.M. Graves Nanoemulsions: formation, structure, and physical properties J. Phys. Condens. Matter 18 2006 R635 R666
30. M.T. Baker, and M. Naguib Propofol: the challenges of formulation Anesthesiology 103 2005 860 876 (Pubitemid 41415536)
31. K. Bouchemal, S. Briancon, E. Perrier, and H. Fessi Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation Int. J. Pharm. 280 2004 241 251 (Pubitemid 38960674)
32. S. Benita, and M.Y. Levy Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization J. Pharm. Sci. 82 1993 1069 1079 (Pubitemid 24004434)
33. K. Shimada, Y. Ohe, T. Ohguni, K. Kawano, J. Ishii, and T. Nakamura Emulsifying properties of α-, β- and γ-cyclodextrins Nippon Shokuhin Kogyo Gakkaishi 38 1991 16 20
34. D. Duchene, A. Bochot, S.C. Yu, C. Pepin, and M. Seiller Cyclodextrins and emulsions Int. J. Pharm. 266 2003 85 90 (Pubitemid 37249310)
35. A. Bochot, L. Trichard, G. Le Bas, H. Alphandary, J.L. Grossiord, D. Duchene, and E. Fattal α-Cyclodextrin/oil beads: an innovative self-assembling system Int. J. Pharm. 339 2007 121 129 (Pubitemid 46977597)
36. M. Inoue, K. Hashizaki, H. Taguchi, and Y. Saito Emulsion preparation using beta-cyclodextrin and its derivatives acting as an emulsifier Chem. Pharm. Bull. (Tokyo) 56 2008 1335 1337
37. K. Hashizaki, T. Kageyama, M. Inoue, H. Taguchi, H. Ueda, and Y. Saito Study on preparation and formation mechanism of n-alkanol/water emulsion using alpha-cyclodextrin Chem. Pharm. Bull. (Tokyo) 55 2007 1620 1625 (Pubitemid 350126172)
38. W. Saenger, and A. Mueller-Fahrnow Cyclodextrins increase surface tension and critical micelle concentrations of detergent solutions Angew. Chem. Int. Ed. Engl. 27 1988 393 394 (Pubitemid 18097783)
39. R.H. Mueller, G.E. Hildebrand, Pharmazeutische Technologie: Moderne Arzneiformen, second ed., Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 1998.
40. N. Otberg, D. Grone, L. Meyer, S. Schanzer, G. Hoffmann, H. Ackermann, W. Sterry, and J. Lademann Water-filtered infrared-A (wIRA) can act as a penetration enhancer for topically applied substances Ger. Med. Sci. 6 2008 1 14
41. M. Kirjavainen, A. Urtti, I. Jaaskelainen, T.M. Suhonen, P. Paronen, R. Valjakka-Koskela, J. Kiesvaara, and J. Monkkonen Interaction of liposomes with human skin in vitro - the influence of lipid composition and structure Biochim. Biophys. Acta 1304 1996 179 189 (Pubitemid 26426990)
42. R.H. Neubert, U. Schmalfuss, C. Huschka, and W.A. Wohlrab Recent developments in the area of dermal drug application Pharm. Ind. 60 1998 149 156 (Pubitemid 28113551)
43. T. Loftsson, S.B. Vogensen, M.E. Brewster, and F. Konradsdottir Effects of cyclodextrins on drug delivery through biological membranes J. Pharm. Sci. 96 2007 2532 2546 (Pubitemid 47597809)
44. K. Cal, and K. Centkowska Use of cyclodextrins in topical formulations: practical aspects Eur. J. Pharm. Biopharm. 68 2008 467 478 (Pubitemid 351318207)
45. R.H. Mueller, M. Radtke, and S.A. Wissing Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations Adv. Drug Deliv. Rev. 54 2002 131 155
46. R.H. Mueller, and A. Dingler The next generation after the liposomes: solid lipid nanoparticles (SLN, Lipopearls) as dermal carrier in cosmetics Eurocosmetics 7-8 1998 19 26
47. T. Loftsson, and N. Bodor Effect of cyclodextrins on percutaneous transport of drugs E.W. Smith, H.I. Maibach, Percutaneous Penetration Enhancers 1995 CRC Press Boca Raton, FL 335 342
48. T. Loftsson, and M. Masson Cyclodextrins in topical drug formulations: theory and practice Int. J. Pharm. 225 2001 15 30 (Pubitemid 32728196)
49. P. Rother, Influence of cyclodextrins on oil-in-water emulsions containing hypromellose (HPMC) as a polymeric emulsifier, PhD Thesis, Faculty of Chemistry and Pharmacy, Eberhard-Karls-Universität, Tübingen, 2009.
50. M. Trotta, F. Pattarino, and T. Ignoni Stability of drug-carrier emulsions containing phosphatidylcholine mixtures Eur. J. Pharm. Biopharm. 53 2002 203 208 (Pubitemid 34189795)
51. P. Ahlin, K. Julijana, S. Pečar, J. Štrancar, and M. Šentjurc The effect of lipophilicity of spin-labeled compounds on their distribution in solid lipid nanoparticle dispersions studied by electron paramagnetic resonance J. Pharm. Sci. 92 2003 58 66 (Pubitemid 36042297)