Continuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass Spectrometry

Mass Spectrometry in Medicinal Chemistry

Volumn 36, Issue , 2007, Pages 185-215

  Irth, Hubertus ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Assay principles; Continuous flow enzyme assays based on mass spectrometry; Continuous flow ligand binding assays based on mass spectrometry; Continuous flow multi protein binding assays using electrospray MS; ESI MS assay of acetylcholinesterase; ESI MS assay of cathepsin B; Mass spectrometry; Miniaturization of electrospray MS assays; Monitoring bioactive compounds; Optimization of MS conditions

Indexed keywords

ASSAYS; BIOCHEMISTRY; DRUG PRODUCTS; LIGANDS; MASS SPECTROMETRY;

ACETYLCHOLINESTERASE; BIOACTIVE COMPOUNDS; CATHEPSIN B; ELECTROSPRAY MS; ENZYME ASSAYS; LIGAND BINDING; PROTEIN BINDING;

ENZYME INHIBITION;

EID: 79959615758     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527610907.ch5     Document Type: Chapter

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