On-line coupling of high-performance liquid chromatography to a continuous-flow enzyme assay based on electrospray ionization mass

Analytical Chemistry

Volumn 76, Issue 11, 2004, Pages 3155-3161

  De Boer, Arjen R ^a   Letzel, Thomas ^a,c   Van Elswijk, Danny A ^b   Lingeman, Henk ^a   Niessen, Wilfried M A ^a   Irth, Hubertus ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b Kiadis BV   (Netherlands)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; ENZYME INHIBITION; ENZYMES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BIOACTIVITIES; FLOW INJECTIONS; MOLECULAR MASSES;

BIOCHEMISTRY;

ENZYME; ENZYME INHIBITOR;

ARTICLE; CONCENTRATION (PARAMETERS); ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; FLOW INJECTION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; IC 50; MICROTITER PLATE ASSAY; MOLECULAR WEIGHT; ONLINE SYSTEM;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 2642512251     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac035380w     Document Type: Article

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