Evidence that carbonyl stress by methylglyoxal exposure induces DNA damage and spindle aberrations, affects mitochondrial integrity in mammalian oocytes and contributes to oocyte ageing

Human Reproduction

Volumn 26, Issue 7, 2011, Pages 1843-1859

  Tatone, Carla ^a   Heizenrieder, Tanja ^b   Di Emidio, Giovanna ^a   Treffon, Patrick ^b   Amicarelli, Fernanda ^a   Seidel, Thorsten ^b   Eichenlaub Ritter, Ursula ^b  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b BIELEFELD UNIVERSITY   (Germany)

Author keywords

advanced glycation end product; ageing; mitochondria; oocyte quality; spindle

Indexed keywords

CARBONYL DERIVATIVE; DNA NUCLEOTIDYLEXOTRANSFERASE; GLYOXALASE; METHYLGLYOXAL;

ANAPHASE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL AGING; CELL DISRUPTION; CELL FUNCTION; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; CELLULAR DISTRIBUTION; CHROMATIN CONDENSATION; DNA DAMAGE; EVIDENCE BASED MEDICINE; FEMALE; FERTILIZATION; IN VITRO STUDY; MAMMAL; METAPHASE; MITOCHONDRION; MOUSE; NONHUMAN; OOCYTE; PROTEIN EXPRESSION; SPINDLE CELL;

MAMMALIA; MUS; VASCONCELLEA CANDICANS;

EID: 79959472523     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der140     Document Type: Article

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