Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis

Oral Oncology

Volumn 46, Issue 4, 2010, Pages 255-262

  Wang, Yu Chu ^a   Tsai, Yi Shan ^a,b   Huang, Jau Ling ^c   Lee, Ka Wo ^d   Kuo, Ching Chuan ^e   Wang, Chung Sheng ^a   Huang, A Mei ^a   Chang, Jang Yang ^e   Jong, Yuh Jyh ^a,b,d   Lin, Chang Shen ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Arecoline; Betel quid; Chromosomal aberrations; Genomic instability; Mitotic arrest; Spindle assembly checkpoint

Indexed keywords

ARECOLINE; AURORA A KINASE; BUB1 RELATED PROTEIN; CYCLIN B1; HISTONE H3; NOCODAZOLE;

ANEUPLOIDY; ARTICLE; BETEL NUT; CARCINOGENESIS; CARCINOGENIC ACTIVITY; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MICRONUCLEUS; MITOSIS SPINDLE; MOUTH CANCER; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ARECA; ARECOLINE; CARCINOGENS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; GENOMIC INSTABILITY; HISTONES; HUMANS; MITOSIS; MITOTIC SPINDLE APPARATUS; MOUTH NEOPLASMS; PROMETAPHASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77949566843     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2010.01.003     Document Type: Article

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