The p53 tumor suppressor is stabilized by inhibitor of growth 1 (ING1) by blocking polyubiquitination

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Thalappilly, Subhash ^a   Feng, Xiaolan ^a   Pastyryeva, Svitlana ^a   Suzuki, Keiko ^a   Muruve, Daniel ^b   Larocque, Daniel ^c   Richard, Stephane ^d   Truss, Matthias ^e   von Deimling, Andreas ^f   Riabowol, Karl ^a   Tallen, Gesche ^e  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c GLAXOSMITHKLINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HERPESVIRUS ASSOCIATED UBIQUITIN SPECIFIC PROTEASE; INHIBITOR OF GROWTH 1 PROTEIN; PROTEIN P53; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ING1 PROTEIN, HUMAN; MUTANT PROTEIN; NUCLEAR PROTEIN; PHOSPHOLIPID; POLYUBIQUITIN; PROTEASOME; SIGNAL PEPTIDE; UBIQUITIN THIOLESTERASE; USP7 PROTEIN, HUMAN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA DAMAGE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INHIBITOR OF GROWTH 1 GENE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UBIQUITINATION; WILD TYPE; ZINC FINGER MOTIF; BIOLOGICAL MODEL; CHEMISTRY; METABOLISM; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

HERPESVIRIDAE;

CELL LINE, TUMOR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MUTANT PROTEINS; NUCLEAR PROTEINS; PHOSPHOLIPIDS; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 79959469514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021065     Document Type: Article

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