-
1
-
-
34547093613
-
Regeneration and plasticity in the brain and spinal cord
-
10.1038/sj.jcbfm.9600486, 17392690
-
Johansson BB. Regeneration and plasticity in the brain and spinal cord. J Cereb Blood Flow Metab 2007, 27:1417-1430. 10.1038/sj.jcbfm.9600486, 17392690.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1417-1430
-
-
Johansson, B.B.1
-
2
-
-
0000103011
-
The Croonian lecture: La fine structure des centres nerveux
-
Ramon y Cajal S. The Croonian lecture: La fine structure des centres nerveux. Proc Roy Soc London 1894, 55:444-467.
-
(1894)
Proc Roy Soc London
, vol.55
, pp. 444-467
-
-
Ramon y Cajal, S.1
-
3
-
-
0000853121
-
Autoradiographic study of degenerative and regenerative proliferation of neuroglia cells with tritiated thymidine
-
10.1016/0014-4886(62)90040-7, 13860749
-
Altman J. Autoradiographic study of degenerative and regenerative proliferation of neuroglia cells with tritiated thymidine. Exp Neurol 1962, 5:302-318. 10.1016/0014-4886(62)90040-7, 13860749.
-
(1962)
Exp Neurol
, vol.5
, pp. 302-318
-
-
Altman, J.1
-
4
-
-
0001159822
-
Are new neurons formed in the brains of adult mammals?
-
10.1126/science.135.3509.1127, 13860748
-
Altman J. Are new neurons formed in the brains of adult mammals?. Science 1962, 135:1127-1128. 10.1126/science.135.3509.1127, 13860748.
-
(1962)
Science
, vol.135
, pp. 1127-1128
-
-
Altman, J.1
-
5
-
-
0013784893
-
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
-
10.1002/cne.901240303, 5861717
-
Altman J, Das GD. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 1965, 124:319-335. 10.1002/cne.901240303, 5861717.
-
(1965)
J Comp Neurol
, vol.124
, pp. 319-335
-
-
Altman, J.1
Das, G.D.2
-
6
-
-
0030894092
-
Stem cells in the central nervous system
-
10.1126/science.276.5309.66, 9082987
-
McKay R. Stem cells in the central nervous system. Science 1997, 276:66-71. 10.1126/science.276.5309.66, 9082987.
-
(1997)
Science
, vol.276
, pp. 66-71
-
-
McKay, R.1
-
7
-
-
0028003778
-
Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells
-
10.1016/0896-6273(94)90046-9, 7946346
-
Morshead CM, Reynolds BA, Craig CG, McBurney MW, Staines WA, Morassutti D, Weiss S, van der Kooy D. Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron 1994, 13:1071-1082. 10.1016/0896-6273(94)90046-9, 7946346.
-
(1994)
Neuron
, vol.13
, pp. 1071-1082
-
-
Morshead, C.M.1
Reynolds, B.A.2
Craig, C.G.3
McBurney, M.W.4
Staines, W.A.5
Morassutti, D.6
Weiss, S.7
van der Kooy, D.8
-
8
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
10.1126/science.1553558, 1553558
-
Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992, 255:1707-1710. 10.1126/science.1553558, 1553558.
-
(1992)
Science
, vol.255
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
9
-
-
0033232043
-
The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease
-
10.1016/S1357-4310(99)01596-8, 10529788
-
Shihabuddin LS, Palmer TD, Gage FH. The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Mol Med Today 1999, 5:474-480. 10.1016/S1357-4310(99)01596-8, 10529788.
-
(1999)
Mol Med Today
, vol.5
, pp. 474-480
-
-
Shihabuddin, L.S.1
Palmer, T.D.2
Gage, F.H.3
-
10
-
-
66549109462
-
Adult hippocampal neurogenesis and related neurotrophic factors
-
Lee E, Son H. Adult hippocampal neurogenesis and related neurotrophic factors. BMB Rep 2009, 42:239-244.
-
(2009)
BMB Rep
, vol.42
, pp. 239-244
-
-
Lee, E.1
Son, H.2
-
11
-
-
77956064613
-
Neurogenesis in mouse models of Alzheimer's disease
-
Chuang TT. Neurogenesis in mouse models of Alzheimer's disease. Biochim Biophys Acta 2010,
-
(2010)
Biochim Biophys Acta
-
-
Chuang, T.T.1
-
12
-
-
0042362874
-
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
-
10.1046/j.1471-4159.2002.01267.x, 12472904
-
Haughey NJ, Nath A, Chan SL, Borchard AC, Rao MS, Mattson MP. Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem 2002, 83:1509-1524. 10.1046/j.1471-4159.2002.01267.x, 12472904.
-
(2002)
J Neurochem
, vol.83
, pp. 1509-1524
-
-
Haughey, N.J.1
Nath, A.2
Chan, S.L.3
Borchard, A.C.4
Rao, M.S.5
Mattson, M.P.6
-
13
-
-
52049090130
-
The effect of amyloidosis-beta and ageing on proliferation of neuronal progenitor cells in APP-transgenic mouse hippocampus and in culture
-
10.1007/s00401-008-0380-4, 18483741
-
Kolecki R, Lafauci G, Rubenstein R, Mazur-Kolecka B, Kaczmarski W, Frackowiak J. The effect of amyloidosis-beta and ageing on proliferation of neuronal progenitor cells in APP-transgenic mouse hippocampus and in culture. Acta Neuropathol 2008, 116:419-424. 10.1007/s00401-008-0380-4, 18483741.
-
(2008)
Acta Neuropathol
, vol.116
, pp. 419-424
-
-
Kolecki, R.1
Lafauci, G.2
Rubenstein, R.3
Mazur-Kolecka, B.4
Kaczmarski, W.5
Frackowiak, J.6
-
14
-
-
33344460074
-
Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to beta-amyloid
-
10.1016/j.neurobiolaging.2005.03.019, 15964102
-
Calafiore M, Battaglia G, Zappala A, Trovato-Salinaro E, Caraci F, Caruso M, Vancheri C, Sortino MA, Nicoletti F, Copani A. Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to beta-amyloid. Neurobiol Aging 2006, 27:606-613. 10.1016/j.neurobiolaging.2005.03.019, 15964102.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 606-613
-
-
Calafiore, M.1
Battaglia, G.2
Zappala, A.3
Trovato-Salinaro, E.4
Caraci, F.5
Caruso, M.6
Vancheri, C.7
Sortino, M.A.8
Nicoletti, F.9
Copani, A.10
-
15
-
-
60849095497
-
Abeta40 promotes neuronal cell fate in neural progenitor cells
-
10.1038/cdd.2008.94, 18566600
-
Chen Y, Dong C. Abeta40 promotes neuronal cell fate in neural progenitor cells. Cell Death Differ 2009, 16:386-394. 10.1038/cdd.2008.94, 18566600.
-
(2009)
Cell Death Differ
, vol.16
, pp. 386-394
-
-
Chen, Y.1
Dong, C.2
-
16
-
-
70349876742
-
Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor
-
10.1016/j.neurobiolaging.2008.02.004, 18374455
-
Sotthibundhu A, Li QX, Thangnipon W, Coulson EJ. Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor. Neurobiol Aging 2009, 30:1975-1985. 10.1016/j.neurobiolaging.2008.02.004, 18374455.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1975-1985
-
-
Sotthibundhu, A.1
Li, Q.X.2
Thangnipon, W.3
Coulson, E.J.4
-
17
-
-
0346458659
-
Increased hippocampal neurogenesis in Alzheimer's disease
-
314187, 14660786
-
Jin K, Peel AL, Mao XO, Xie L, Cottrell BA, Henshall DC, Greenberg DA. Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci USA 2004, 101:343-347. 314187, 14660786.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 343-347
-
-
Jin, K.1
Peel, A.L.2
Mao, X.O.3
Xie, L.4
Cottrell, B.A.5
Henshall, D.C.6
Greenberg, D.A.7
-
18
-
-
37549013706
-
Failure of neuronal maturation in Alzheimer disease dentate gyrus
-
10.1097/nen.0b013e318160c5db, 18091557
-
Li B, Yamamori H, Tatebayashi Y, Shafit-Zagardo B, Tanimukai H, Chen S, Iqbal K, Grundke-Iqbal I. Failure of neuronal maturation in Alzheimer disease dentate gyrus. J Neuropathol Exp Neurol 2008, 67:78-84. 10.1097/nen.0b013e318160c5db, 18091557.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 78-84
-
-
Li, B.1
Yamamori, H.2
Tatebayashi, Y.3
Shafit-Zagardo, B.4
Tanimukai, H.5
Chen, S.6
Iqbal, K.7
Grundke-Iqbal, I.8
-
19
-
-
33748790666
-
Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus
-
10.1016/j.nbd.2006.04.017, 16814555
-
Boekhoorn K, Joels M, Lucassen PJ. Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus. Neurobiol Dis 2006, 24:1-14. 10.1016/j.nbd.2006.04.017, 16814555.
-
(2006)
Neurobiol Dis
, vol.24
, pp. 1-14
-
-
Boekhoorn, K.1
Joels, M.2
Lucassen, P.J.3
-
20
-
-
36749010157
-
Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin
-
10.1093/brain/awm264, 18055496
-
Verwer RW, Sluiter AA, Balesar RA, Baayen JC, Noske DP, Dirven CM, Wouda J, van Dam AM, Lucassen PJ, Swaab DF. Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin. Brain 2007, 130:3321-3335. 10.1093/brain/awm264, 18055496.
-
(2007)
Brain
, vol.130
, pp. 3321-3335
-
-
Verwer, R.W.1
Sluiter, A.A.2
Balesar, R.A.3
Baayen, J.C.4
Noske, D.P.5
Dirven, C.M.6
Wouda, J.7
van Dam, A.M.8
Lucassen, P.J.9
Swaab, D.F.10
-
21
-
-
33747817727
-
Altered neurogenesis in Alzheimer's disease
-
10.1016/j.jpsychores.2006.07.017, 16938507
-
Ziabreva I, Perry E, Perry R, Minger SL, Ekonomou A, Przyborski S, Ballard C. Altered neurogenesis in Alzheimer's disease. J Psychosom Res 2006, 61:311-316. 10.1016/j.jpsychores.2006.07.017, 16938507.
-
(2006)
J Psychosom Res
, vol.61
, pp. 311-316
-
-
Ziabreva, I.1
Perry, E.2
Perry, R.3
Minger, S.L.4
Ekonomou, A.5
Przyborski, S.6
Ballard, C.7
-
22
-
-
33746418611
-
Isolation of neural precursor cells from Alzheimer's disease and aged control postmortem brain
-
10.1016/j.neurobiolaging.2005.05.004, 15979211
-
Lovell MA, Geiger H, Van Zant GE, Lynn BC, Markesbery WR. Isolation of neural precursor cells from Alzheimer's disease and aged control postmortem brain. Neurobiol Aging 2006, 27:909-917. 10.1016/j.neurobiolaging.2005.05.004, 15979211.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 909-917
-
-
Lovell, M.A.1
Geiger, H.2
Van Zant, G.E.3
Lynn, B.C.4
Markesbery, W.R.5
-
23
-
-
33745999815
-
Amyloid-beta impairs development of neuronal progenitor cells by oxidative mechanisms
-
10.1016/j.neurobiolaging.2005.07.006, 16105709
-
Mazur-Kolecka B, Golabek A, Nowicki K, Flory M, Frackowiak J. Amyloid-beta impairs development of neuronal progenitor cells by oxidative mechanisms. Neurobiol Aging 2006, 27:1181-1192. 10.1016/j.neurobiolaging.2005.07.006, 16105709.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1181-1192
-
-
Mazur-Kolecka, B.1
Golabek, A.2
Nowicki, K.3
Flory, M.4
Frackowiak, J.5
-
24
-
-
49249116020
-
Behavior of neural stem cells in the Alzheimer brain
-
10.1007/s00018-008-8053-y, 18500448
-
Waldau B, Shetty AK. Behavior of neural stem cells in the Alzheimer brain. Cell Mol Life Sci 2008, 65:2372-2384. 10.1007/s00018-008-8053-y, 18500448.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2372-2384
-
-
Waldau, B.1
Shetty, A.K.2
-
25
-
-
0036703488
-
The adult substantia nigra contains progenitor cells with neurogenic potential
-
Lie DC, Dziewczapolski G, Willhoite AR, Kaspar BK, Shults CW, Gage FH. The adult substantia nigra contains progenitor cells with neurogenic potential. J Neurosci 2002, 22:6639-6649.
-
(2002)
J Neurosci
, vol.22
, pp. 6639-6649
-
-
Lie, D.C.1
Dziewczapolski, G.2
Willhoite, A.R.3
Kaspar, B.K.4
Shults, C.W.5
Gage, F.H.6
-
26
-
-
33746771344
-
Proliferation of neural precursors in the subventricular zone after chemical lesions of the nigrostriatal pathway in rat brain
-
10.1016/j.brainres.2006.05.111, 16843444
-
Liu BF, Gao EJ, Zeng XZ, Ji M, Cai Q, Lu Q, Yang H, Xu QY. Proliferation of neural precursors in the subventricular zone after chemical lesions of the nigrostriatal pathway in rat brain. Brain Res 2006, 1106:30-39. 10.1016/j.brainres.2006.05.111, 16843444.
-
(2006)
Brain Res
, vol.1106
, pp. 30-39
-
-
Liu, B.F.1
Gao, E.J.2
Zeng, X.Z.3
Ji, M.4
Cai, Q.5
Lu, Q.6
Yang, H.7
Xu, Q.Y.8
-
27
-
-
39149132799
-
Increased progenitor cell proliferation and astrogenesis in the partial progressive 6-hydroxydopamine model of Parkinson's disease
-
10.1016/j.neuroscience.2007.11.036, 18201835
-
Aponso PM, Faull RL, Connor B. Increased progenitor cell proliferation and astrogenesis in the partial progressive 6-hydroxydopamine model of Parkinson's disease. Neuroscience 2008, 151:1142-1153. 10.1016/j.neuroscience.2007.11.036, 18201835.
-
(2008)
Neuroscience
, vol.151
, pp. 1142-1153
-
-
Aponso, P.M.1
Faull, R.L.2
Connor, B.3
-
28
-
-
40449139321
-
Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease
-
10.1523/JNEUROSCI.3040-07.2008, 18322092
-
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Horsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci 2008, 28:2471-2484. 10.1523/JNEUROSCI.3040-07.2008, 18322092.
-
(2008)
J Neurosci
, vol.28
, pp. 2471-2484
-
-
Nuber, S.1
Petrasch-Parwez, E.2
Winner, B.3
Winkler, J.4
von Horsten, S.5
Schmidt, T.6
Boy, J.7
Kuhn, M.8
Nguyen, H.P.9
Teismann, P.10
Schulz, J.B.11
Neumann, M.12
Pichler, B.J.13
Reischl, G.14
Holzmann, C.15
Schmitt, I.16
Bornemann, A.17
Kuhn, W.18
Zimmermann, F.19
Servadio, A.20
Riess, O.21
more..
-
29
-
-
3042822087
-
Dopamine depletion impairs precursor cell proliferation in Parkinson disease
-
10.1038/nn1265, 15195095
-
Hoglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, Hirsch EC. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci 2004, 7:726-735. 10.1038/nn1265, 15195095.
-
(2004)
Nat Neurosci
, vol.7
, pp. 726-735
-
-
Hoglinger, G.U.1
Rizk, P.2
Muriel, M.P.3
Duyckaerts, C.4
Oertel, W.H.5
Caille, I.6
Hirsch, E.C.7
-
30
-
-
33846203285
-
Dopamine and adult neurogenesis
-
10.1111/j.1471-4159.2006.04241.x, 17101030
-
Borta A, Hoglinger GU. Dopamine and adult neurogenesis. J Neurochem 2007, 100:587-595. 10.1111/j.1471-4159.2006.04241.x, 17101030.
-
(2007)
J Neurochem
, vol.100
, pp. 587-595
-
-
Borta, A.1
Hoglinger, G.U.2
-
31
-
-
0035873718
-
Nerve growth factor rapidly induces prolonged acetylcholine release from cultured basal forebrain neurons: differentiation between neuromodulatory and neurotrophic influences
-
Auld DS, Mennicken F, Quirion R. Nerve growth factor rapidly induces prolonged acetylcholine release from cultured basal forebrain neurons: differentiation between neuromodulatory and neurotrophic influences. J Neurosci 2001, 21:3375-3382.
-
(2001)
J Neurosci
, vol.21
, pp. 3375-3382
-
-
Auld, D.S.1
Mennicken, F.2
Quirion, R.3
-
32
-
-
21544446985
-
Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
-
10.1523/JNEUROSCI.4601-04.2005, 15987955
-
Baquet ZC, Bickford PC, Jones KR. Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. J Neurosci 2005, 25:6251-6259. 10.1523/JNEUROSCI.4601-04.2005, 15987955.
-
(2005)
J Neurosci
, vol.25
, pp. 6251-6259
-
-
Baquet, Z.C.1
Bickford, P.C.2
Jones, K.R.3
-
33
-
-
0028343266
-
Role of neurotrophins in mouse neuronal development
-
Klein R. Role of neurotrophins in mouse neuronal development. FASEB J 1994, 8:738-744.
-
(1994)
FASEB J
, vol.8
, pp. 738-744
-
-
Klein, R.1
-
34
-
-
0029082495
-
Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons
-
394540, 7556091
-
Davies AM, Minichiello L, Klein R. Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons. EMBO J 1995, 14:4482-4489. 394540, 7556091.
-
(1995)
EMBO J
, vol.14
, pp. 4482-4489
-
-
Davies, A.M.1
Minichiello, L.2
Klein, R.3
-
35
-
-
0030759543
-
Neurotrophin regulation of the developing nervous system: analyses of knockout mice
-
10.1515/REVNEURO.1997.8.1.13, 9402642
-
Conover JC, Yancopoulos GD. Neurotrophin regulation of the developing nervous system: analyses of knockout mice. Rev Neurosci 1997, 8:13-27. 10.1515/REVNEURO.1997.8.1.13, 9402642.
-
(1997)
Rev Neurosci
, vol.8
, pp. 13-27
-
-
Conover, J.C.1
Yancopoulos, G.D.2
-
36
-
-
77949700751
-
Brain-derived neurotrophic factor and the development of structural neuronal connectivity
-
Cohen-Cory S, Kidane AH, Shirkey NJ, Marshak S. Brain-derived neurotrophic factor and the development of structural neuronal connectivity. Dev Neurobiol 70:271-288.
-
Dev Neurobiol
, vol.70
, pp. 271-288
-
-
Cohen-Cory, S.1
Kidane, A.H.2
Shirkey, N.J.3
Marshak, S.4
-
37
-
-
0034672398
-
Neuroprotective signaling and the aging brain: take away my food and let me run
-
10.1016/S0006-8993(00)02790-6, 11119686
-
Mattson MP. Neuroprotective signaling and the aging brain: take away my food and let me run. Brain Res 2000, 886:47-53. 10.1016/S0006-8993(00)02790-6, 11119686.
-
(2000)
Brain Res
, vol.886
, pp. 47-53
-
-
Mattson, M.P.1
-
38
-
-
33845577779
-
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease
-
10.1016/j.exger.2006.08.009, 17049785
-
Cole GM, Frautschy SA. The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease. Exp Gerontol 2007, 42:10-21. 10.1016/j.exger.2006.08.009, 17049785.
-
(2007)
Exp Gerontol
, vol.42
, pp. 10-21
-
-
Cole, G.M.1
Frautschy, S.A.2
-
39
-
-
41249088472
-
Treatment of Parkinson's disease with trophic factors
-
10.1016/j.nurt.2008.02.003, 18394569
-
Peterson AL, Nutt JG. Treatment of Parkinson's disease with trophic factors. Neurotherapeutics 2008, 5:270-280. 10.1016/j.nurt.2008.02.003, 18394569.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 270-280
-
-
Peterson, A.L.1
Nutt, J.G.2
-
40
-
-
77950256736
-
The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders
-
Lanni C, Stanga S, Racchi M, Govoni S. The expanding universe of neurotrophic factors: therapeutic potential in aging and age-associated disorders. Curr Pharm Des 16:698-717.
-
Curr Pharm Des
, vol.16
, pp. 698-717
-
-
Lanni, C.1
Stanga, S.2
Racchi, M.3
Govoni, S.4
-
41
-
-
33749010358
-
Neurotrophin-regulated signalling pathways
-
10.1098/rstb.2006.1894, 1664664, 16939974
-
Reichardt LF. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 2006, 361:1545-1564. 10.1098/rstb.2006.1894, 1664664, 16939974.
-
(2006)
Philos Trans R Soc Lond B Biol Sci
, vol.361
, pp. 1545-1564
-
-
Reichardt, L.F.1
-
42
-
-
33747051514
-
Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins
-
10.1523/JNEUROSCI.1560-06.2006, 16855103
-
Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ. Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J Neurosci 2006, 26:7756-7766. 10.1523/JNEUROSCI.1560-06.2006, 16855103.
-
(2006)
J Neurosci
, vol.26
, pp. 7756-7766
-
-
Volosin, M.1
Song, W.2
Almeida, R.D.3
Kaplan, D.R.4
Hempstead, B.L.5
Friedman, W.J.6
-
43
-
-
69749119998
-
Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons
-
10.1016/j.expneurol.2009.07.002, 19615368
-
Piltonen M, Bespalov MM, Ervasti D, Matilainen T, Sidorova YA, Rauvala H, Saarma M, Mannisto PT. Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons. Exp Neurol 2009, 219:499-506. 10.1016/j.expneurol.2009.07.002, 19615368.
-
(2009)
Exp Neurol
, vol.219
, pp. 499-506
-
-
Piltonen, M.1
Bespalov, M.M.2
Ervasti, D.3
Matilainen, T.4
Sidorova, Y.A.5
Rauvala, H.6
Saarma, M.7
Mannisto, P.T.8
-
44
-
-
0038575486
-
Regulation of natural cell death in dopaminergic neurons of the substantia nigra by striatal glial cell line-derived neurotrophic factor in vivo
-
Oo TF, Kholodilov N, Burke RE. Regulation of natural cell death in dopaminergic neurons of the substantia nigra by striatal glial cell line-derived neurotrophic factor in vivo. J Neurosci 2003, 23:5141-5148.
-
(2003)
J Neurosci
, vol.23
, pp. 5141-5148
-
-
Oo, T.F.1
Kholodilov, N.2
Burke, R.E.3
-
45
-
-
0030795798
-
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
-
10.1073/pnas.94.16.8818, 23145, 9238061
-
Bilang-Bleuel A, Revah F, Colin P, Locquet I, Robert JJ, Mallet J, Horellou P. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci USA 1997, 94:8818-8823. 10.1073/pnas.94.16.8818, 23145, 9238061.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8818-8823
-
-
Bilang-Bleuel, A.1
Revah, F.2
Colin, P.3
Locquet, I.4
Robert, J.J.5
Mallet, J.6
Horellou, P.7
-
46
-
-
12844287442
-
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
-
10.1523/JNEUROSCI.4421-04.2005, 15673656
-
Eslamboli A, Georgievska B, Ridley RM, Baker HF, Muzyczka N, Burger C, Mandel RJ, Annett L, Kirik D. Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. J Neurosci 2005, 25:769-777. 10.1523/JNEUROSCI.4421-04.2005, 15673656.
-
(2005)
J Neurosci
, vol.25
, pp. 769-777
-
-
Eslamboli, A.1
Georgievska, B.2
Ridley, R.M.3
Baker, H.F.4
Muzyczka, N.5
Burger, C.6
Mandel, R.J.7
Annett, L.8
Kirik, D.9
-
47
-
-
0142106351
-
Novel functions and signalling pathways for GDNF
-
10.1242/jcs.00786, 12953054
-
Sariola H, Saarma M. Novel functions and signalling pathways for GDNF. J Cell Sci 2003, 116:3855-3862. 10.1242/jcs.00786, 12953054.
-
(2003)
J Cell Sci
, vol.116
, pp. 3855-3862
-
-
Sariola, H.1
Saarma, M.2
-
48
-
-
33751099301
-
RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice
-
10.1523/JNEUROSCI.1876-06.2006, 17065462
-
Jain S, Golden JP, Wozniak D, Pehek E, Johnson EM, Milbrandt J. RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. J Neurosci 2006, 26:11230-11238. 10.1523/JNEUROSCI.1876-06.2006, 17065462.
-
(2006)
J Neurosci
, vol.26
, pp. 11230-11238
-
-
Jain, S.1
Golden, J.P.2
Wozniak, D.3
Pehek, E.4
Johnson, E.M.5
Milbrandt, J.6
-
49
-
-
33947278829
-
Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system
-
10.1371/journal.pbio.0050039, 1808500, 17298183
-
Kramer ER, Aron L, Ramakers GM, Seitz S, Zhuang X, Beyer K, Smidt MP, Klein R. Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol 2007, 5:e39. 10.1371/journal.pbio.0050039, 1808500, 17298183.
-
(2007)
PLoS Biol
, vol.5
-
-
Kramer, E.R.1
Aron, L.2
Ramakers, G.M.3
Seitz, S.4
Zhuang, X.5
Beyer, K.6
Smidt, M.P.7
Klein, R.8
-
50
-
-
68049127516
-
Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
-
10.1523/JNEUROSCI.0833-09.2009, 19641128
-
Voutilainen MH, Back S, Porsti E, Toppinen L, Lindgren L, Lindholm P, Peranen J, Saarma M, Tuominen RK. Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease. J Neurosci 2009, 29:9651-9659. 10.1523/JNEUROSCI.0833-09.2009, 19641128.
-
(2009)
J Neurosci
, vol.29
, pp. 9651-9659
-
-
Voutilainen, M.H.1
Back, S.2
Porsti, E.3
Toppinen, L.4
Lindgren, L.5
Lindholm, P.6
Peranen, J.7
Saarma, M.8
Tuominen, R.K.9
-
51
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
-
10.1038/nature05957, 17611540
-
Lindholm P, Voutilainen MH, Lauren J, Peranen J, Leppanen VM, Andressoo JO, Lindahl M, Janhunen S, Kalkkinen N, Timmusk T, Tuominen RK, Saarma M. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 2007, 448:73-77. 10.1038/nature05957, 17611540.
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.H.2
Lauren, J.3
Peranen, J.4
Leppanen, V.M.5
Andressoo, J.O.6
Lindahl, M.7
Janhunen, S.8
Kalkkinen, N.9
Timmusk, T.10
Tuominen, R.K.11
Saarma, M.12
-
52
-
-
56649124807
-
Glutamate and neurotrophic factors in neuronal plasticity and disease
-
10.1196/annals.1418.005, 2614307, 19076369
-
Mattson MP. Glutamate and neurotrophic factors in neuronal plasticity and disease. Ann N Y Acad Sci 2008, 1144:97-112. 10.1196/annals.1418.005, 2614307, 19076369.
-
(2008)
Ann N Y Acad Sci
, vol.1144
, pp. 97-112
-
-
Mattson, M.P.1
-
53
-
-
53949111613
-
New insights into brain BDNF function in normal aging and Alzheimer disease
-
10.1016/j.brainresrev.2008.07.007, 18708092
-
Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S. New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev 2008, 59:201-220. 10.1016/j.brainresrev.2008.07.007, 18708092.
-
(2008)
Brain Res Rev
, vol.59
, pp. 201-220
-
-
Tapia-Arancibia, L.1
Aliaga, E.2
Silhol, M.3
Arancibia, S.4
-
54
-
-
33747891466
-
Stage-dependent BDNF serum concentrations in Alzheimer's disease
-
10.1007/s00702-005-0397-y, 16362629
-
Laske C, Stransky E, Leyhe T, Eschweiler GW, Wittorf A, Richartz E, Bartels M, Buchkremer G, Schott K. Stage-dependent BDNF serum concentrations in Alzheimer's disease. J Neural Transm 2006, 113:1217-1224. 10.1007/s00702-005-0397-y, 16362629.
-
(2006)
J Neural Transm
, vol.113
, pp. 1217-1224
-
-
Laske, C.1
Stransky, E.2
Leyhe, T.3
Eschweiler, G.W.4
Wittorf, A.5
Richartz, E.6
Bartels, M.7
Buchkremer, G.8
Schott, K.9
-
55
-
-
37849050242
-
Neurotrophic factors in Alzheimer's disease: role of axonal transport
-
2228393, 18184369
-
Schindowski K, Belarbi K, Buee L. Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes Brain Behav 2008, 7(Suppl 1):43-56. 2228393, 18184369.
-
(2008)
Genes Brain Behav
, vol.7
, Issue.SUPPL. 1
, pp. 43-56
-
-
Schindowski, K.1
Belarbi, K.2
Buee, L.3
-
56
-
-
3342908640
-
Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
-
10.1523/JNEUROSCI.5463-03.2004, 15282285
-
Tong L, Balazs R, Thornton PL, Cotman CW. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J Neurosci 2004, 24:6799-6809. 10.1523/JNEUROSCI.5463-03.2004, 15282285.
-
(2004)
J Neurosci
, vol.24
, pp. 6799-6809
-
-
Tong, L.1
Balazs, R.2
Thornton, P.L.3
Cotman, C.W.4
-
57
-
-
0028125079
-
Development of effective therapy for Alzheimer's disease based on neurotrophic factors
-
Hefti F. Development of effective therapy for Alzheimer's disease based on neurotrophic factors. Neurobiol Aging 1994, 15(Suppl 2):S193-194.
-
(1994)
Neurobiol Aging
, vol.15
, Issue.SUPPL. 2
-
-
Hefti, F.1
-
58
-
-
0043025510
-
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease
-
10.1001/archneur.60.8.1143, 12925373
-
Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST. Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Arch Neurol 2003, 60:1143-1148. 10.1001/archneur.60.8.1143, 12925373.
-
(2003)
Arch Neurol
, vol.60
, pp. 1143-1148
-
-
Mufson, E.J.1
Ikonomovic, M.D.2
Styren, S.D.3
Counts, S.E.4
Wuu, J.5
Leurgans, S.6
Bennett, D.A.7
Cochran, E.J.8
DeKosky, S.T.9
-
59
-
-
67849129074
-
Brain-derived neurotrophic factor levels in Alzheimer's disease
-
2787708, 19363274
-
O'Bryant SE, Hobson V, Hall JR, Waring SC, Chan W, Massman P, Lacritz L, Cullum CM, Diaz-Arrastia R. Brain-derived neurotrophic factor levels in Alzheimer's disease. J Alzheimers Dis 2009, 17:337-341. 2787708, 19363274.
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 337-341
-
-
O'Bryant, S.E.1
Hobson, V.2
Hall, J.R.3
Waring, S.C.4
Chan, W.5
Massman, P.6
Lacritz, L.7
Cullum, C.M.8
Diaz-Arrastia, R.9
-
60
-
-
4644268336
-
Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease
-
10.1002/ana.20233, 15455399
-
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Ann Neurol 2004, 56:520-531. 10.1002/ana.20233, 15455399.
-
(2004)
Ann Neurol
, vol.56
, pp. 520-531
-
-
Counts, S.E.1
Nadeem, M.2
Wuu, J.3
Ginsberg, S.D.4
Saragovi, H.U.5
Mufson, E.J.6
-
61
-
-
34248178972
-
The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease
-
10.1007/s11064-006-9270-0, 17404842
-
Cuello AC, Bruno MA. The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease. Neurochem Res 2007, 32:1041-1045. 10.1007/s11064-006-9270-0, 17404842.
-
(2007)
Neurochem Res
, vol.32
, pp. 1041-1045
-
-
Cuello, A.C.1
Bruno, M.A.2
-
62
-
-
75049084504
-
Cholinergic involvement in Alzheimer's disease. A link with NGF maturation and degradation
-
10.1007/s12031-009-9238-z, 19680822
-
Cuello AC, Bruno MA, Allard S, Leon W, Iulita MF. Cholinergic involvement in Alzheimer's disease. A link with NGF maturation and degradation. J Mol Neurosci 2010, 40:230-235. 10.1007/s12031-009-9238-z, 19680822.
-
(2010)
J Mol Neurosci
, vol.40
, pp. 230-235
-
-
Cuello, A.C.1
Bruno, M.A.2
Allard, S.3
Leon, W.4
Iulita, M.F.5
-
63
-
-
35748937677
-
Beta/A4-Amyloid increases nerve growth factor production in rat primary hippocampal astrocyte cultures
-
10.1016/j.ijdevneu.2007.05.010, 17646078
-
Schulte-Herbruggen O, Hamker U, Meske V, Danker-Hopfe H, Ohm TG, Hellweg R. Beta/A4-Amyloid increases nerve growth factor production in rat primary hippocampal astrocyte cultures. Int J Dev Neurosci 2007, 25:387-390. 10.1016/j.ijdevneu.2007.05.010, 17646078.
-
(2007)
Int J Dev Neurosci
, vol.25
, pp. 387-390
-
-
Schulte-Herbruggen, O.1
Hamker, U.2
Meske, V.3
Danker-Hopfe, H.4
Ohm, T.G.5
Hellweg, R.6
-
64
-
-
0034959811
-
Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain
-
10.1016/S0891-0618(01)00115-6, 11429269
-
Chauhan NB, Siegel GJ, Lee JM. Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain. J Chem Neuroanat 2001, 21:277-288. 10.1016/S0891-0618(01)00115-6, 11429269.
-
(2001)
J Chem Neuroanat
, vol.21
, pp. 277-288
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lee, J.M.3
-
65
-
-
66149096521
-
Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys
-
10.1089/hum.2008.201, 2725183,2725183, 19254173
-
Eberling JL, Kells AP, Pivirotto P, Beyer J, Bringas J, Federoff HJ, Forsayeth J, Bankiewicz KS. Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys. Hum Gene Ther 2009, 20:511-518. 10.1089/hum.2008.201, 2725183,2725183, 19254173.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 511-518
-
-
Eberling, J.L.1
Kells, A.P.2
Pivirotto, P.3
Beyer, J.4
Bringas, J.5
Federoff, H.J.6
Forsayeth, J.7
Bankiewicz, K.S.8
-
66
-
-
29144536727
-
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease
-
10.1111/j.1460-9568.2005.04503.x, 16324109
-
Ericson C, Georgievska B, Lundberg C. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. Eur J Neurosci 2005, 22:2755-2764. 10.1111/j.1460-9568.2005.04503.x, 16324109.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2755-2764
-
-
Ericson, C.1
Georgievska, B.2
Lundberg, C.3
-
67
-
-
23644437308
-
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease
-
10.1016/j.brainres.2005.05.072, 2581863, 16018990
-
Sun M, Kong L, Wang X, Lu XG, Gao Q, Geller AI. Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. Brain Res 2005, 1052:119-129. 10.1016/j.brainres.2005.05.072, 2581863, 16018990.
-
(2005)
Brain Res
, vol.1052
, pp. 119-129
-
-
Sun, M.1
Kong, L.2
Wang, X.3
Lu, X.G.4
Gao, Q.5
Geller, A.I.6
-
68
-
-
42549170505
-
Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles
-
10.1186/1471-2202-9-37, 2330056, 18402684
-
Cao H, Zhang GR, Wang X, Kong L, Geller AI. Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles. BMC Neurosci 2008, 9:37. 10.1186/1471-2202-9-37, 2330056, 18402684.
-
(2008)
BMC Neurosci
, vol.9
, pp. 37
-
-
Cao, H.1
Zhang, G.R.2
Wang, X.3
Kong, L.4
Geller, A.I.5
-
69
-
-
70350495615
-
Glial cell-line derived neurotrophic factor (GDNF) concentrations in cerebrospinal fluid and serum of patients with early Alzheimer's disease and normal controls
-
Straten G, Eschweiler GW, Maetzler W, Laske C, Leyhe T. Glial cell-line derived neurotrophic factor (GDNF) concentrations in cerebrospinal fluid and serum of patients with early Alzheimer's disease and normal controls. J Alzheimers Dis 2009, 18:331-337.
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 331-337
-
-
Straten, G.1
Eschweiler, G.W.2
Maetzler, W.3
Laske, C.4
Leyhe, T.5
-
70
-
-
70449362319
-
Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease
-
Marksteiner J, Kemmler G, Weiss EM, Knaus G, Ullrich C, Mechteriakov S, Oberbauer H, Auffinger S, Hinterholzl J, Hinterhuber H, Humpel C. Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 2009,
-
(2009)
Neurobiol Aging
-
-
Marksteiner, J.1
Kemmler, G.2
Weiss, E.M.3
Knaus, G.4
Ullrich, C.5
Mechteriakov, S.6
Oberbauer, H.7
Auffinger, S.8
Hinterholzl, J.9
Hinterhuber, H.10
Humpel, C.11
-
71
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt JG, Burchiel KJ, Comella CL, Jankovic J, Lang AE, Laws ER, Lozano AM, Penn RD, Simpson RK, Stacy M, Wooten GF. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 2003, 60:69-73.
-
(2003)
Neurology
, vol.60
, pp. 69-73
-
-
Nutt, J.G.1
Burchiel, K.J.2
Comella, C.L.3
Jankovic, J.4
Lang, A.E.5
Laws, E.R.6
Lozano, A.M.7
Penn, R.D.8
Simpson, R.K.9
Stacy, M.10
Wooten, G.F.11
-
72
-
-
61649114966
-
Plasticity in neurological disorders and challenges for noninvasive brain stimulation (NBS)
-
10.1186/1743-0003-6-4, 2649147, 19222843
-
Thickbroom GW, Mastaglia FL. Plasticity in neurological disorders and challenges for noninvasive brain stimulation (NBS). J Neuroeng Rehabil 2009, 6:4. 10.1186/1743-0003-6-4, 2649147, 19222843.
-
(2009)
J Neuroeng Rehabil
, vol.6
, pp. 4
-
-
Thickbroom, G.W.1
Mastaglia, F.L.2
-
73
-
-
67349213205
-
Synaptic degeneration in Alzheimer's disease
-
10.1007/s00401-009-0536-x, 19390859
-
Arendt T. Synaptic degeneration in Alzheimer's disease. Acta Neuropathol 2009, 118:167-179. 10.1007/s00401-009-0536-x, 19390859.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 167-179
-
-
Arendt, T.1
-
74
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
10.1016/j.neuron.2004.09.010, 15450169
-
Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 2004, 44:181-193. 10.1016/j.neuron.2004.09.010, 15450169.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
75
-
-
0037884977
-
Synaptic plasticity in animal models of early Alzheimer's disease
-
1693153, 12740129
-
Rowan MJ, Klyubin I, Cullen WK, Anwyl R. Synaptic plasticity in animal models of early Alzheimer's disease. Philos Trans R Soc Lond B Biol Sci 2003, 358:821-828. 1693153, 12740129.
-
(2003)
Philos Trans R Soc Lond B Biol Sci
, vol.358
, pp. 821-828
-
-
Rowan, M.J.1
Klyubin, I.2
Cullen, W.K.3
Anwyl, R.4
-
76
-
-
33846633336
-
Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
-
10.1523/JNEUROSCI.3501-06.2007, 17251419
-
Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 2007, 27:796-807. 10.1523/JNEUROSCI.3501-06.2007, 17251419.
-
(2007)
J Neurosci
, vol.27
, pp. 796-807
-
-
Lacor, P.N.1
Buniel, M.C.2
Furlow, P.W.3
Clemente, A.S.4
Velasco, P.T.5
Wood, M.6
Viola, K.L.7
Klein, W.L.8
-
77
-
-
0042838303
-
Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
10.1073/pnas.1834302100, 193576, 12925731
-
Gong Y, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, Krafft GA, Klein WL. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc Natl Acad Sci USA 2003, 100:10417-10422. 10.1073/pnas.1834302100, 193576, 12925731.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
Krafft, G.A.7
Klein, W.L.8
-
78
-
-
33947177730
-
Linking cell-cycle dysfunction in Alzheimer's disease to a failure of synaptic plasticity
-
Arendt T, Bruckner MK. Linking cell-cycle dysfunction in Alzheimer's disease to a failure of synaptic plasticity. Biochim Biophys Acta 2007, 1772:413-421.
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 413-421
-
-
Arendt, T.1
Bruckner, M.K.2
-
79
-
-
0032906126
-
Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation
-
10.1046/j.1460-9568.1999.00593.x, 10215928
-
Mikkonen M, Soininen H, Tapiola T, Alafuzoff I, Miettinen R. Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation. Eur J Neurosci 1999, 11:1754-1764. 10.1046/j.1460-9568.1999.00593.x, 10215928.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 1754-1764
-
-
Mikkonen, M.1
Soininen, H.2
Tapiola, T.3
Alafuzoff, I.4
Miettinen, R.5
-
80
-
-
0025033996
-
Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease
-
10.1016/0022-510X(90)90182-M, 1977892
-
Jorgensen OS, Brooksbank BW, Balazs R. Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease. J Neurol Sci 1990, 98:63-79. 10.1016/0022-510X(90)90182-M, 1977892.
-
(1990)
J Neurol Sci
, vol.98
, pp. 63-79
-
-
Jorgensen, O.S.1
Brooksbank, B.W.2
Balazs, R.3
-
81
-
-
64749084436
-
Chronic brain inflammation impairs two forms of long-term potentiation in the rat hippocampal CA1 area
-
10.1016/j.neulet.2009.03.079, 19429126
-
Min SS, Quan HY, Ma J, Han JS, Jeon BH, Seol GH. Chronic brain inflammation impairs two forms of long-term potentiation in the rat hippocampal CA1 area. Neurosci Lett 2009, 456:20-24. 10.1016/j.neulet.2009.03.079, 19429126.
-
(2009)
Neurosci Lett
, vol.456
, pp. 20-24
-
-
Min, S.S.1
Quan, H.Y.2
Ma, J.3
Han, J.S.4
Jeon, B.H.5
Seol, G.H.6
-
82
-
-
0042125603
-
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals
-
Arendt T, Stieler J, Strijkstra AM, Hut RA, Rudiger J, Van der Zee EA, Harkany T, Holzer M, Hartig W. Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals. J Neurosci 2003, 23:6972-6981.
-
(2003)
J Neurosci
, vol.23
, pp. 6972-6981
-
-
Arendt, T.1
Stieler, J.2
Strijkstra, A.M.3
Hut, R.A.4
Rudiger, J.5
Van der Zee, E.A.6
Harkany, T.7
Holzer, M.8
Hartig, W.9
-
83
-
-
60849116119
-
Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein
-
10.1016/j.neuroscience.2009.01.021, 2670358, 19361478
-
Watson JB, Hatami A, David H, Masliah E, Roberts K, Evans CE, Levine MS. Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein. Neuroscience 2009, 159:501-513. 10.1016/j.neuroscience.2009.01.021, 2670358, 19361478.
-
(2009)
Neuroscience
, vol.159
, pp. 501-513
-
-
Watson, J.B.1
Hatami, A.2
David, H.3
Masliah, E.4
Roberts, K.5
Evans, C.E.6
Levine, M.S.7
-
84
-
-
0345269239
-
Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice
-
10.1097/00001756-200302100-00012, 12598733
-
Steidl JV, Gomez-Isla T, Mariash A, Ashe KH, Boland LM. Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice. Neuroreport 2003, 14:219-223. 10.1097/00001756-200302100-00012, 12598733.
-
(2003)
Neuroreport
, vol.14
, pp. 219-223
-
-
Steidl, J.V.1
Gomez-Isla, T.2
Mariash, A.3
Ashe, K.H.4
Boland, L.M.5
-
85
-
-
47049117548
-
Striatal synaptic changes in experimental parkinsonism: role of NMDA receptor trafficking in PSD
-
Picconi B, Ghiglieri V, Bagetta V, Barone I, Sgobio C, Calabresi P. Striatal synaptic changes in experimental parkinsonism: role of NMDA receptor trafficking in PSD. Parkinsonism Relat Disord 2008, 14(Suppl 2):S145-149.
-
(2008)
Parkinsonism Relat Disord
, vol.14
, Issue.SUPPL. 2
-
-
Picconi, B.1
Ghiglieri, V.2
Bagetta, V.3
Barone, I.4
Sgobio, C.5
Calabresi, P.6
-
86
-
-
38949177433
-
Striatal plasticity and medium spiny neuron dendritic remodeling in parkinsonism
-
Deutch AY, Colbran RJ, Winder DJ. Striatal plasticity and medium spiny neuron dendritic remodeling in parkinsonism. Parkinsonism Relat Disord 2007, 13(Suppl 3):S251-258.
-
(2007)
Parkinsonism Relat Disord
, vol.13
, Issue.SUPPL. 3
-
-
Deutch, A.Y.1
Colbran, R.J.2
Winder, D.J.3
-
87
-
-
0026571233
-
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease
-
10.1073/pnas.89.2.569, 48280, 1309947
-
Mufson EJ, Kordower JH. Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease. Proc Natl Acad Sci USA 1992, 89:569-573. 10.1073/pnas.89.2.569, 48280, 1309947.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 569-573
-
-
Mufson, E.J.1
Kordower, J.H.2
-
88
-
-
0028965223
-
Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration
-
Chen KS, Gage FH. Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration. J Neurosci 1995, 15:2819-2825.
-
(1995)
J Neurosci
, vol.15
, pp. 2819-2825
-
-
Chen, K.S.1
Gage, F.H.2
-
89
-
-
0028276809
-
Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
-
10.1073/pnas.91.11.5104, 43940, 8197193
-
Frim DM, Uhler TA, Galpern WR, Beal MF, Breakefield XO, Isacson O. Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci USA 1994, 91:5104-5108. 10.1073/pnas.91.11.5104, 43940, 8197193.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5104-5108
-
-
Frim, D.M.1
Uhler, T.A.2
Galpern, W.R.3
Beal, M.F.4
Breakefield, X.O.5
Isacson, O.6
-
90
-
-
0032845156
-
Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy
-
10.1073/pnas.96.19.10893, 17979, 10485922
-
Smith DE, Roberts J, Gage FH, Tuszynski MH. Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proc Natl Acad Sci USA 1999, 96:10893-10898. 10.1073/pnas.96.19.10893, 17979, 10485922.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10893-10898
-
-
Smith, D.E.1
Roberts, J.2
Gage, F.H.3
Tuszynski, M.H.4
-
91
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
10.1038/nm1239, 15852017
-
Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, Kordower JH, Gall C, Conner J. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005, 11:551-555. 10.1038/nm1239, 15852017.
-
(2005)
Nat Med
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
U, H.S.5
Bakay, R.6
Patel, P.7
Blesch, A.8
Vahlsing, H.L.9
Ho, G.10
Tong, G.11
Potkin, S.G.12
Fallon, J.13
Hansen, L.14
Mufson, E.J.15
Kordower, J.H.16
Gall, C.17
Conner, J.18
-
92
-
-
0036729074
-
The use of foetal human brain tissue as brain implants: phenotype manipulation by genetic manipulation and biochemical induction
-
Bradford HF. The use of foetal human brain tissue as brain implants: phenotype manipulation by genetic manipulation and biochemical induction. Keio J Med 2002, 51:148-153.
-
(2002)
Keio J Med
, vol.51
, pp. 148-153
-
-
Bradford, H.F.1
-
93
-
-
0029932534
-
Long-term outcome of unilaterally transplanted parkinsonian patients. I. Clinical approach
-
Defer GL, Geny C, Ricolfi F, Fenelon G, Monfort JC, Remy P, Villafane G, Jeny R, Samson Y, Keravel Y, Gaston A, Degos JD, Peschanski M, Cesaro P, Nguyen JP. Long-term outcome of unilaterally transplanted parkinsonian patients. I. Clinical approach. Brain 1996, 119(Pt 1):41-50.
-
(1996)
Brain
, vol.119
, Issue.PART 1
, pp. 41-50
-
-
Defer, G.L.1
Geny, C.2
Ricolfi, F.3
Fenelon, G.4
Monfort, J.C.5
Remy, P.6
Villafane, G.7
Jeny, R.8
Samson, Y.9
Keravel, Y.10
Gaston, A.11
Degos, J.D.12
Peschanski, M.13
Cesaro, P.14
Nguyen, J.P.15
-
94
-
-
0033053030
-
Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
-
10.1001/archneur.56.2.179, 10025423
-
Hauser RA, Freeman TB, Snow BJ, Nauert M, Gauger L, Kordower JH, Olanow CW. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch Neurol 1999, 56:179-187. 10.1001/archneur.56.2.179, 10025423.
-
(1999)
Arch Neurol
, vol.56
, pp. 179-187
-
-
Hauser, R.A.1
Freeman, T.B.2
Snow, B.J.3
Nauert, M.4
Gauger, L.5
Kordower, J.H.6
Olanow, C.W.7
-
95
-
-
21944436225
-
Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease
-
10.1093/brain/awh510, 2610438, 15872020
-
Mendez I, Sanchez-Pernaute R, Cooper O, Vinuela A, Ferrari D, Bjorklund L, Dagher A, Isacson O. Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain 2005, 128:1498-1510. 10.1093/brain/awh510, 2610438, 15872020.
-
(2005)
Brain
, vol.128
, pp. 1498-1510
-
-
Mendez, I.1
Sanchez-Pernaute, R.2
Cooper, O.3
Vinuela, A.4
Ferrari, D.5
Bjorklund, L.6
Dagher, A.7
Isacson, O.8
-
96
-
-
43249085326
-
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
-
10.1038/nm1752, 2656682, 18391961
-
Mendez I, Vinuela A, Astradsson A, Mukhida K, Hallett P, Robertson H, Tierney T, Holness R, Dagher A, Trojanowski JQ, Isacson O. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med 2008, 14:507-509. 10.1038/nm1752, 2656682, 18391961.
-
(2008)
Nat Med
, vol.14
, pp. 507-509
-
-
Mendez, I.1
Vinuela, A.2
Astradsson, A.3
Mukhida, K.4
Hallett, P.5
Robertson, H.6
Tierney, T.7
Holness, R.8
Dagher, A.9
Trojanowski, J.Q.10
Isacson, O.11
-
97
-
-
0035826089
-
Transplantation of embryonic dopamine neurons for severe Parkinson's disease
-
10.1056/NEJM200103083441002, 11236774
-
Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, Dillon S, Winfield H, Culver S, Trojanowski JQ, Eidelberg D, Fahn S. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001, 344:710-719. 10.1056/NEJM200103083441002, 11236774.
-
(2001)
N Engl J Med
, vol.344
, pp. 710-719
-
-
Freed, C.R.1
Greene, P.E.2
Breeze, R.E.3
Tsai, W.Y.4
DuMouchel, W.5
Kao, R.6
Dillon, S.7
Winfield, H.8
Culver, S.9
Trojanowski, J.Q.10
Eidelberg, D.11
Fahn, S.12
-
98
-
-
33846919884
-
Concise review: therapeutic strategies for Parkinson disease based on the modulation of adult neurogenesis
-
10.1634/stemcells.2006-0364, 17082225
-
Geraerts M, Krylyshkina O, Debyser Z, Baekelandt V. Concise review: therapeutic strategies for Parkinson disease based on the modulation of adult neurogenesis. Stem Cells 2007, 25:263-270. 10.1634/stemcells.2006-0364, 17082225.
-
(2007)
Stem Cells
, vol.25
, pp. 263-270
-
-
Geraerts, M.1
Krylyshkina, O.2
Debyser, Z.3
Baekelandt, V.4
-
99
-
-
30944470080
-
Adult stem cells for neuronal repair
-
Barzilay R, Levy YS, Melamed E, Offen D. Adult stem cells for neuronal repair. Isr Med Assoc J 2006, 8:61-66.
-
(2006)
Isr Med Assoc J
, vol.8
, pp. 61-66
-
-
Barzilay, R.1
Levy, Y.S.2
Melamed, E.3
Offen, D.4
-
100
-
-
0037133163
-
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
-
10.1073/pnas.022438099, 122367, 11782534
-
Bjorklund LM, Sanchez-Pernaute R, Chung S, Andersson T, Chen IY, McNaught KS, Brownell AL, Jenkins BG, Wahlestedt C, Kim KS, Isacson O. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 2002, 99:2344-2349. 10.1073/pnas.022438099, 122367, 11782534.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2344-2349
-
-
Bjorklund, L.M.1
Sanchez-Pernaute, R.2
Chung, S.3
Andersson, T.4
Chen, I.Y.5
McNaught, K.S.6
Brownell, A.L.7
Jenkins, B.G.8
Wahlestedt, C.9
Kim, K.S.10
Isacson, O.11
-
101
-
-
33645803034
-
Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease
-
10.2152/jmi.53.61, 16537997
-
Wang Q, Matsumoto Y, Shindo T, Miyake K, Shindo A, Kawanishi M, Kawai N, Tamiya T, Nagao S. Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease. J Med Invest 2006, 53:61-69. 10.2152/jmi.53.61, 16537997.
-
(2006)
J Med Invest
, vol.53
, pp. 61-69
-
-
Wang, Q.1
Matsumoto, Y.2
Shindo, T.3
Miyake, K.4
Shindo, A.5
Kawanishi, M.6
Kawai, N.7
Tamiya, T.8
Nagao, S.9
-
102
-
-
67549138948
-
Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases
-
Sadan O, Shemesh N, Cohen Y, Melamed E, Offen D. Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases. Isr Med Assoc J 2009, 11:201-204.
-
(2009)
Isr Med Assoc J
, vol.11
, pp. 201-204
-
-
Sadan, O.1
Shemesh, N.2
Cohen, Y.3
Melamed, E.4
Offen, D.5
-
103
-
-
62949238951
-
The neuroprotective effect of dental pulp cells in models of Alzheimer's and Parkinson's disease
-
10.1007/s00702-008-0135-3, 18972063
-
Apel C, Forlenza OV, de Paula VJ, Talib LL, Denecke B, Eduardo CP, Gattaz WF. The neuroprotective effect of dental pulp cells in models of Alzheimer's and Parkinson's disease. J Neural Transm 2009, 116:71-78. 10.1007/s00702-008-0135-3, 18972063.
-
(2009)
J Neural Transm
, vol.116
, pp. 71-78
-
-
Apel, C.1
Forlenza, O.V.2
de Paula, V.J.3
Talib, L.L.4
Denecke, B.5
Eduardo, C.P.6
Gattaz, W.F.7
-
104
-
-
55049099234
-
Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease
-
10.1634/stemcells.2008-0074, 18535154
-
Murrell W, Wetzig A, Donnellan M, Feron F, Burne T, Meedeniya A, Kesby J, Bianco J, Perry C, Silburn P, Mackay-Sim A. Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease. Stem Cells 2008, 26:2183-2192. 10.1634/stemcells.2008-0074, 18535154.
-
(2008)
Stem Cells
, vol.26
, pp. 2183-2192
-
-
Murrell, W.1
Wetzig, A.2
Donnellan, M.3
Feron, F.4
Burne, T.5
Meedeniya, A.6
Kesby, J.7
Bianco, J.8
Perry, C.9
Silburn, P.10
Mackay-Sim, A.11
|